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Chambers KT, Cooper MA, Swearingen AR, Brookheart RT, Schweitzer GG, Weinheimer CJ, Kovacs A, Koves TR, Muoio DM, McCommis KS, Finck BN. Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations. JCI Insight. 2021 May 10;6(9). doi: 10.1172/jci.insight.134340. PubMed PMID: 33986192; PubMed Central PMCID: PMC8262319.
Liss KHH, Ek SE, Lutkewitte AJ, Pietka TA, He M, Skaria P, Tycksen E, Ferguson D, Blanc V, Graham MJ, Hall AM, McGill MR, McCommis KS, Finck BN. Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis. Liver Transpl. 2021 Jan;27(1):116-133. doi: 10.1002/lt.25886. Epub 2020 Oct 22. PubMed PMID: 32916011; PubMed Central PMCID: PMC7785593.
Kumar S, Peterson TR. Moonshots for aging. Nutr Healthy Aging. 2020 Nov 3;5(4):239-246. doi: 10.3233/NHA-190064. Review. PubMed PMID: 33344796; PubMed Central PMCID: PMC7740370.
McCommis KS, Kovacs A, Weinheimer CJ, Shew TM, Koves TR, Ilkayeva OR, Kamm DR, Pyles KD, King MT, Veech RL, DeBosch BJ, Muoio DM, Gross RW, Finck BN. Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice. Nat Metab. 2020 Nov;2(11):1232-1247. doi: 10.1038/s42255-020-00296-1. Epub 2020 Oct 26. PubMed PMID: 33106690; PubMed Central PMCID: PMC7957960.
Surface LE, Burrow DT, Li J, Park J, Kumar S, Lyu C, Song N, Yu Z, Rajagopal A, Bae Y, Lee BH, Mumm S, Gu CC, Baker JC, Mohseni M, Sum M, Huskey M, Duan S, Bijanki VN, Civitelli R, Gardner MJ, McAndrew CM, Ricci WM, Gurnett CA, Diemer K, Wan F, Costantino CL, Shannon KM, Raje N, Dodson TB, Haber DA, Carette JE, Varadarajan M, Brummelkamp TR, Birsoy K, Sabatini DM, Haller G, Peterson TR. ATRAID regulates the action of nitrogen-containing bisphosphonates on bone. Sci Transl Med. 2020 May 20;12(544). doi: 10.1126/scitranslmed.aav9166. PubMed PMID: 32434850; PubMed Central PMCID: PMC7882121.
Kumar S, Peterson TR. Moonshots for aging. Nutrition and Healthy Aging. 2019 July; pre-press(pre-press):1-8. doi: 10.3233/NHA-190064.
Oughli H, Lenze EJ, Locke AE, Yingling MD, Zhong Y, Miller JP, Reynolds CF 3rd, Mulsant BH, Newcomer JW, Peterson TR, Müller DJ, Nicol GE. Getting to precision psychopharmacology: Combining clinical and genetic information to predict fat gain from aripiprazole. J Psychiatr Res. 2019 Jul;114:67-74. doi: 10.1016/j.jpsychires.2019.04.017. Epub 2019 Apr 23. PubMed PMID: 31039482; PubMed Central PMCID: PMC6546502.
Park J, Jacobs N, Peterson TR. Cell fitness is an omniphenotype. Version: 3. doi [preprint]. 2018 December; [revised 2019 August]: 10.1101/487157Available from: doi: 10.1101/487157.
Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. Mapping the Genetic Landscape of Human Cells. Cell. 2018 Aug 9;174(4):953-967.e22. doi: 10.1016/j.cell.2018.06.010. Epub 2018 Jul 19. PubMed PMID: 30033366; PubMed Central PMCID: PMC6426455.
Rotroff DM, Yee SW, Zhou K, Marvel SW, Shah HS, Jack JR, Havener TM, Hedderson MM, Kubo M, Herman MA, Gao H, Mychaleckyi JC, McLeod HL, Doria A, Giacomini KM, Pearson ER, Wagner MJ, Buse JB, Motsinger-Reif AA. Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes. Diabetes. 2018 Jul;67(7):1428-1440. doi: 10.2337/db17-1164. Epub 2018 Apr 12. PubMed PMID: 29650774; PubMed Central PMCID: PMC6014560.
Surface LE, Park J, Kumar S, Burrow D, Li J, Song NJ, Peterson TR. ATRAID, a genetic factor that regulates the clinical action of nitrogen-containing bisphosphonates on bone. Version: 1. doi [Preprint]. 2018 June. 10.1101/338350Available from: doi: 10.1101/338350.
Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates. Elife. 2018 May 10;7. doi: 10.7554/eLife.36620. PubMed PMID: 29745899; PubMed Central PMCID: PMC6021172.
Rawson KS, Dixon D, Civitelli R, Peterson TR, Mulsant BH, Reynolds CF 3rd, Lenze EJ. Bone Turnover with Venlafaxine Treatment in Older Adults with Depression. J Am Geriatr Soc. 2017 Sep;65(9):2057-2063. doi: 10.1111/jgs.14936. Epub 2017 May 26. PubMed PMID: 28555718; PubMed Central PMCID: PMC5626017.
Civitelli R, Peterson T. Toward personalized calcium and vitamin D supplementation. Am J Clin Nutr. 2017 Apr;105(4):777-778. doi: 10.3945/ajcn.117.154278. Epub 2017 Mar 22. PubMed PMID: 28330910; PubMed Central PMCID: PMC5366059.
Birsoy K, Wang T, Possemato R, Yilmaz OH, Koch CE, Chen WW, Hutchins AW, Gultekin Y, Peterson TR, Carette JE, Brummelkamp TR, Clish CB, Sabatini DM. MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors. Nat Genet. 2013 Jan;45(1):104-8. doi: 10.1038/ng.2471. Epub 2012 Dec 2. PubMed PMID: 23202129; PubMed Central PMCID: PMC3530647.
Wan M, Leavens KF, Saleh D, Easton RM, Guertin DA, Peterson TR, Kaestner KH, Sabatini DM, Birnbaum MJ. Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c. Cell Metab. 2011 Oct 5;14(4):516-27. doi: 10.1016/j.cmet.2011.09.001. PubMed PMID: 21982711; PubMed Central PMCID: PMC3190164.
Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, Sabatini DM. mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. Cell. 2011 Aug 5;146(3):408-20. doi: 10.1016/j.cell.2011.06.034. PubMed PMID: 21816276; PubMed Central PMCID: PMC3336367.
Hsu PP, Kang SA, Rameseder J, Zhang Y, Ottina KA, Lim D, Peterson TR, Choi Y, Gray NS, Yaffe MB, Marto JA, Sabatini DM. The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science. 2011 Jun 10;332(6035):1317-22. doi: 10.1126/science.1199498. PubMed PMID: 21659604; PubMed Central PMCID: PMC3177140.
Chen CH, Shaikenov T, Peterson TR, Aimbetov R, Bissenbaev AK, Lee SW, Wu J, Lin HK, Sarbassov dos D. ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor. Sci Signal. 2011 Feb 22;4(161):ra10. doi: 10.1126/scisignal.2001731. PubMed PMID: 21343617; NIHMSID:NIHMS342593.
Sengupta S, Peterson TR, Laplante M, Oh S, Sabatini DM. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature. 2010 Dec 23;468(7327):1100-4. doi: 10.1038/nature09584. PubMed PMID: 21179166.
Sengupta S, Peterson TR, Sabatini DM. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol Cell. 2010 Oct 22;40(2):310-22. doi: 10.1016/j.molcel.2010.09.026. Review. PubMed PMID: 20965424; PubMed Central PMCID: PMC2993060.
Boulbes D, Chen CH, Shaikenov T, Agarwal NK, Peterson TR, Addona TA, Keshishian H, Carr SA, Magnuson MA, Sabatini DM, Sarbassov dos D. Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2. Mol Cancer Res. 2010 Jun;8(6):896-906. doi: 10.1158/1541-7786.MCR-09-0409. Epub 2010 May 25. PubMed PMID: 20501647; PubMed Central PMCID: PMC2896829.
Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell. 2009 May 29;137(5):873-86. doi: 10.1016/j.cell.2009.03.046. Epub 2009 May 14. PubMed PMID: 19446321; PubMed Central PMCID: PMC2758791.
Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008 Jun 13;320(5882):1496-501. doi: 10.1126/science.1157535. Epub 2008 May 22. PubMed PMID: 18497260; PubMed Central PMCID: PMC2475333.
Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM. PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Mol Cell. 2007 Mar 23;25(6):903-15. doi: 10.1016/j.molcel.2007.03.003. PubMed PMID: 17386266; NIHMSID:NIHMS350071.
Dib A, Peterson TR, Raducha-Grace L, Zingone A, Zhan F, Hanamura I, Barlogie B, Shaughnessy J Jr, Kuehl WM. Paradoxical expression of INK4c in proliferative multiple myeloma tumors: bi-allelic deletion vs increased expression. Cell Div. 2006 Oct 18;1:23. doi: 10.1186/1747-1028-1-23. PubMed PMID: 17049078; PubMed Central PMCID: PMC1634742.
Peterson TR, Sabatini DM. eIF3: a connecTOR of S6K1 to the translation preinitiation complex. Mol Cell. 2005 Dec 9;20(5):655-7. doi: 10.1016/j.molcel.2005.11.016. Review. PubMed PMID: 16337588.
Simosa HF, Wang G, Sui X, Peterson T, Narra V, Altieri DC, Conte MS. Survivin expression is up-regulated in vascular injury and identifies a distinct cellular phenotype. J Vasc Surg. 2005 Apr;41(4):682-90. doi: 10.1016/j.jvs.2005.01.006. PubMed PMID: 15874934.
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