My Bibliography

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Ascoli C, Gottardi R, Petracchi D. Scanning probe microscopy. In: Palumbo G, Pratesi R, editors. Lasers and current optical techniques in biology London: The Royal Chemical Society; 2004. 375-427p.

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Cesare Ascoli, Riccardo Gottardi, Donatella Petracchi. Scanning probe microscopy. 2004; :375--428. doi: 10.1039/9781847551207-00375.

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Marsano A, Wendt D, Raiteri R, Gottardi R, Stolz M, Wirz D, Daniels AU, Salter D, Jakob M, Quinn TM, Martin I. Use of hydrodynamic forces to engineer cartilaginous tissues resembling the non-uniform structure and function of meniscus. Biomaterials. 2006 Dec;27(35):5927-34. doi: 10.1016/j.biomaterials.2006.08.020. Epub 2006 Sep 1. PubMed PMID: 16949667.

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The arthroscopic SFM - a minimally invasive nanotool for probing articular cartilage. 2006 December.

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Riccardo Gottardi, Robert Raiteri, Martin Stolz, Robert Kilger, Christian Candrian, Marko Loparic, Sylvie Miot, Marcel Düggelin, Daniel Mathys, Markus Dürrenberger, Laure Aeschimann, Raphael Imer, Urs Staufer, Ivan Martin, Niklaus Friederich, Ueli Aebi. ASSESSMENT OF EARLY OSTEOARTHRITIS IN HUMAN KNEE CARTILAGE BY SCANNING FORCE MICROSCOPY. Journal of Biomechanics. 2008 July; 41:S169. doi: 10.1016/s0021-9290(08)70169-6.

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Stolz M, Gottardi R, Raiteri R, Miot S, Martin I, Imer R, Staufer U, Raducanu A, Düggelin M, Baschong W, Daniels AU, Friederich NF, Aszodi A, Aebi U. Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nat Nanotechnol. 2009 Mar;4(3):186-92. doi: 10.1038/nnano.2008.410. Epub 2009 Feb 1. PubMed PMID: 19265849.

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Taffetani M, Bertarelli E, Gottardi R, Raiteri R, Vena P. Modeling of the Frequency Response to Dynamic Nanoindentation of Soft Hydrated Anisotropic Materials: Application to Articular Cartilage. Computer modeling in engineering & sciences : CMES. 2012; 87(5):433-460. doi: doi:10.3970/cmes.2012.087.433.

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Taffetani, M., Bertarelli, E., Gottardi, R., Raiteri, R., Vena, P.. Modelling of the frequency response to dynamic nanoindentation of soft hydrated anisotropic materials: Application to articular cartilage. CMES - Computer Modeling in Engineering and Sciences. 2012; 87(5):433-460.

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Kamalasanan K, Gottardi R, Tan S, Chen Y, Godugu B, Rothstein S, Balazs AC, Star A, Little SR. "Zero-dimensional" single-walled carbon nanotubes. Angew Chem Int Ed Engl. 2013 Oct 18;52(43):11308-12. doi: 10.1002/anie.201305526. Epub 2013 Sep 5. PubMed PMID: 24038731.

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Gottardi R, Douradinha B. Carbon nanotubes as a novel tool for vaccination against infectious diseases and cancer. J Nanobiotechnology. 2013 Sep 11;11:30. doi: 10.1186/1477-3155-11-30. Review. PubMed PMID: 24025216; PubMed Central PMCID: PMC3846653.

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Yang G, Rothrauff BB, Lin H, Gottardi R, Alexander PG, Tuan RS. Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix. Biomaterials. 2013 Dec;34(37):9295-306. doi: 10.1016/j.biomaterials.2013.08.054. Epub 2013 Sep 14. PubMed PMID: 24044998; PubMed Central PMCID: PMC3951997.

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Lozito TP, Alexander PG, Lin H, Gottardi R, Cheng AW, Tuan RS. Three-dimensional osteochondral microtissue to model pathogenesis of osteoarthritis. Stem Cell Res Ther. 2013;4 Suppl 1(Suppl 1):S6. doi: 10.1186/scrt367. Epub 2013 Dec 20. Review. PubMed PMID: 24564995; PubMed Central PMCID: PMC4029306.

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Thompson WR, Gottardi R, Stearns KM, Rubin J, Ambrosio F, Tuan RS. Biologics in Cartilage, Bone Repair, and Regeneration. In: Hughes C, editor. Applications of Regenerative Medicine to Orthopaedic Physical Therapy La Crosse, WI: Orthopaedic Section APTA; 2013.

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“Zero-Dimensional” Single-Walled Carbon Nanotubes. 2013. doi: 10.1002/ange.201305526.

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Taffetani M, Gottardi R, Gastaldi D, Raiteri R, Vena P. Poroelastic response of articular cartilage by nanoindentation creep tests at different characteristic lengths. Med Eng Phys. 2014 Jul;36(7):850-8. doi: 10.1016/j.medengphy.2014.03.008. Epub 2014 May 10. PubMed PMID: 24814573.

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Lin H, Lozito TP, Alexander PG, Gottardi R, Tuan RS. Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1β. Mol Pharm. 2014 Jul 7;11(7):2203-12. doi: 10.1021/mp500136b. Epub 2014 Jun 2. PubMed PMID: 24830762; PubMed Central PMCID: PMC4086740.

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Alexander PG, Gottardi R, Lin H, Lozito TP, Tuan RS. Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseases. Exp Biol Med (Maywood). 2014 Sep;239(9):1080-95. doi: 10.1177/1535370214539232. Epub 2014 Jul 3. Review. PubMed PMID: 24994814; PubMed Central PMCID: PMC5413932.

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D'Amore A, Amoroso N, Gottardi R, Hobson C, Carruthers C, Watkins S, Wagner WR, Sacks MS. From single fiber to macro-level mechanics: A structural finite-element model for elastomeric fibrous biomaterials. J Mech Behav Biomed Mater. 2014 Nov;39:146-61. doi: 10.1016/j.jmbbm.2014.07.016. Epub 2014 Aug 1. PubMed PMID: 25128869; PubMed Central PMCID: PMC4165725.

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Glowacki AJ, Gottardi R, Yoshizawa S, Cavalla F, Garlet GP, Sfeir C, Little SR. Strategies to direct the enrichment, expansion, and recruitment of regulatory cells for the treatment of disease. Ann Biomed Eng. 2015 Mar;43(3):593-602. doi: 10.1007/s10439-014-1125-2. Epub 2014 Sep 23. Review. PubMed PMID: 25245220; PubMed Central PMCID: PMC4370807.

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William R. Thompson, Riccardo Gottardi, Kristen M. Stearns, Janet Rubin, Fabrisia Ambrosio, Rocky S. Tuan. Biologics in Cartilage, Bone Repair, and Regeneration. 2014 January; :1--24. doi: 10.17832/isc.2014.23.2.5.

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Taffetani M, Raiteri R, Gottardi R, Gastaldi D, Vena P. A quantitative interpretation of the response of articular cartilage to atomic force microscopy-based dynamic nanoindentation tests. J Biomech Eng. 2015 Jul;137(7). doi: 10.1115/1.4030175. Epub 2015 Jun 2. PubMed PMID: 25807472.

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Bayer EA, Gottardi R, Fedorchak MV, Little SR. The scope and sequence of growth factor delivery for vascularized bone tissue regeneration. J Control Release. 2015 Dec 10;219:129-140. doi: 10.1016/j.jconrel.2015.08.004. Epub 2015 Aug 8. Review. PubMed PMID: 26264834.

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Gottardi R. Towards a minimally invasive sampling tool for high resolution tissue analytical mapping. Nanotechnology. 2015 Sep 18;26(37):372501. doi: 10.1088/0957-4484/26/37/372501. Epub 2015 Aug 24. PubMed PMID: 26302485.

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Guaragno ML, Gottardi R, Fedorchak MV, Roy A, Kumta PN, Little SR. One-step synthesis of fluorescently labelled, single-walled carbon nanotubes. Chem Commun (Camb). 2015 Dec 18;51(97):17233-6. doi: 10.1039/c5cc05573c. PubMed PMID: 26458421.

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Iannetti L, D'Urso G, Conoscenti G, Cutrì E, Tuan RS, Raimondi MT, Gottardi R, Zunino P. Distributed and Lumped Parameter Models for the Characterization of High Throughput Bioreactors. PLoS One. 2016;11(9):e0162774. doi: 10.1371/journal.pone.0162774. eCollection 2016. PubMed PMID: 27669413; PubMed Central PMCID: PMC5036894.

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Numpaisal PO, Rothrauff BB, Gottardi R, Chien CL, Tuan RS. Rapidly dissociated autologous meniscus tissue enhances meniscus healing: An in vitro study. Connect Tissue Res. 2017 May-Jul;58(3-4):355-365. doi: 10.1080/03008207.2016.1245727. Epub 2016 Oct 11. PubMed PMID: 27726454.

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Gottardi R, Hansen U, Raiteri R, Loparic M, Düggelin M, Mathys D, Friederich NF, Bruckner P, Stolz M. Supramolecular Organization of Collagen Fibrils in Healthy and Osteoarthritic Human Knee and Hip Joint Cartilage. PLoS One. 2016;11(10):e0163552. doi: 10.1371/journal.pone.0163552. eCollection 2016. PubMed PMID: 27780246; PubMed Central PMCID: PMC5079628.

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Rothrauff BB, Shimomura K, Gottardi R, Alexander PG, Tuan RS. Anatomical region-dependent enhancement of 3-dimensional chondrogenic differentiation of human mesenchymal stem cells by soluble meniscus extracellular matrix. Acta Biomater. 2017 Feb;49:140-151. doi: 10.1016/j.actbio.2016.11.046. Epub 2016 Nov 19. PubMed PMID: 27876676; PubMed Central PMCID: PMC5543932.

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Liou JJ, Langhans MT, Gottardi R, Tuan RS. Injury and Repair of Tendon, Ligament and Meniscus. In: Lawrence J, Baptista P, Atala A, Van Beusekom M, editors. Translating Regenerative Medicine to the Clinic Cambridge, MA: Academic Press; 2016. Chapter 6; p.75-88.

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Sun AX, Numpaisal P, Gottardi R, Shen H, Yang G, Tuan RS. Cell and Biomimetic Scaffold Based Approaches for Cartilage Regeneration. In: Musahl V, Tuan R, editors. Operative Techniques in Orthopaedics Cambridge: Elsevier; 2016. p.135-146.

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Aaron X. Sun, Piya-on Numpaisal, Riccardo Gottardi, He Shen, Guang Yang, Rocky S. Tuan. Cell and Biomimetic Scaffold-Based Approaches for Cartilage Regeneration. Operative Techniques in Orthopaedics. 2016 September; 26(3):135--146. doi: 10.1053/j.oto.2016.06.003.

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Jr-Jiun Liou, Mark T. Langhans, Riccardo Gottardi, Rocky S. Tuan. Injury and Repair of Tendon, Ligament, and Meniscus. 2016; :75--88. doi: 10.1016/b978-0-12-800548-4.00006-1.

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Liou, J.-J., Langhans, M.T., Gottardi, R., Tuan, R.S.. Injury and Repair of Tendon, Ligament, and Meniscus. In: Translating Regenerative Medicine to the Clinic 2016. 75-88p.

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Coluccino L, Peres C, Gottardi R, Bianchini P, Diaspro A, Ceseracciu L. Anisotropy in the viscoelastic response of knee meniscus cartilage. J Appl Biomater Funct Mater. 2017 Jan 26;15(1):e77-e83. doi: 10.5301/jabfm.5000319. PubMed PMID: 27647392.

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Bayer EA, Jordan J, Roy A, Gottardi R, Fedorchak MV, Kumta PN, Little SR. (*) Programmed Platelet-Derived Growth Factor-BB and Bone Morphogenetic Protein-2 Delivery from a Hybrid Calcium Phosphate/Alginate Scaffold. Tissue Eng Part A. 2017 Dec;23(23-24):1382-1393. doi: 10.1089/ten.TEA.2017.0027. Epub 2017 Jun 27. PubMed PMID: 28537482; PubMed Central PMCID: PMC5729879.

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Rothrauff BB, Coluccino L, Gottardi R, Ceseracciu L, Scaglione S, Goldoni L, Tuan RS. Efficacy of thermoresponsive, photocrosslinkable hydrogels derived from decellularized tendon and cartilage extracellular matrix for cartilage tissue engineering. J Tissue Eng Regen Med. 2018 Jan;12(1):e159-e170. doi: 10.1002/term.2465. Epub 2017 Aug 21. PubMed PMID: 28486778; PubMed Central PMCID: PMC5814356.

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Ratay ML, Bellotti E, Gottardi R, Little SR. Modern Therapeutic Approaches for Noninfectious Ocular Diseases Involving Inflammation. Adv Healthc Mater. 2017 Dec;6(23). doi: 10.1002/adhm.201700733. Epub 2017 Oct 16. Review. PubMed PMID: 29034584; PubMed Central PMCID: PMC5915344.

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Nichols DA, Sondh IS, Little SR, Zunino P, Gottardi R. Design and validation of an osteochondral bioreactor for the screening of treatments for osteoarthritis. Biomed Microdevices. 2018 Feb 14;20(1):18. doi: 10.1007/s10544-018-0264-x. PubMed PMID: 29445972; PubMed Central PMCID: PMC5813085.

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Coluccino L, Gottardi R, Ayadi F, Athanassiou A, Tuan RS, Ceseracciu L. Porous Poly(vinyl alcohol)-Based Hydrogel for Knee Meniscus Functional Repair. ACS Biomater Sci Eng. 2018 May 14;4(5):1518-1527. doi: 10.1021/acsbiomaterials.7b00879. Epub 2018 Mar 22. PubMed PMID: 33445309.

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Mittwede PN, Gottardi R, Alexander PG, Tarkin IS, Tuan RS. Clinical Applications of Bone Tissue Engineering in Orthopedic Trauma. Curr Pathobiol Rep. 2018 Jun;6(2):99-108. doi: 10.1007/s40139-018-0166-x. Epub 2018 Apr 19. PubMed PMID: 36506709; PubMed Central PMCID: PMC9733044.

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Pirosa A, Gottardi R, Alexander PG, Tuan RS. Engineering in-vitro stem cell-based vascularized bone models for drug screening and predictive toxicology. Stem Cell Res Ther. 2018 Apr 20;9(1):112. doi: 10.1186/s13287-018-0847-8. Review. PubMed PMID: 29678192; PubMed Central PMCID: PMC5910611.

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Nichols DA, Sondh IS, Little SR, Zunino P, Gottardi R. Correction to: Design and validation of an osteochondral bioreactor for the screening of treatments for osteoarthritis. Biomed Microdevices. 2018 May 8;20(2):39. doi: 10.1007/s10544-018-0283-7. PubMed PMID: 29736756; PubMed Central PMCID: PMC6828244.

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Sasaki H, Rothrauff BB, Alexander PG, Lin H, Gottardi R, Fu FH, Tuan RS. In Vitro Repair of Meniscal Radial Tear With Hydrogels Seeded With Adipose Stem Cells and TGF-β3. Am J Sports Med. 2018 Aug;46(10):2402-2413. doi: 10.1177/0363546518782973. Epub 2018 Jul 12. PubMed PMID: 30001494.

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Gottardi R, Stoddart MJ. Regenerative Rehabilitation of the Musculoskeletal System. J Am Acad Orthop Surg. 2018 Aug 1;26(15):e321-e323. doi: 10.5435/JAAOS-D-18-00220. PubMed PMID: 29985246; PubMed Central PMCID: PMC6529175.

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Iseki T, Rothrauff BB, Kihara S, Sasaki H, Yoshiya S, Fu FH, Tuan RS, Gottardi R. Dynamic Compressive Loading Improves Cartilage Repair in an In Vitro Model of Microfracture: Comparison of 2 Mechanical Loading Regimens on Simulated Microfracture Based on Fibrin Gel Scaffolds Encapsulating Connective Tissue Progenitor Cells. Am J Sports Med. 2019 Jul;47(9):2188-2199. doi: 10.1177/0363546519855645. PubMed PMID: 31307219; PubMed Central PMCID: PMC6637720.

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Gottardi R. Load-induced osteoarthritis on a chip. Nat Biomed Eng. 2019 Jul;3(7):502-503. doi: 10.1038/s41551-019-0427-y. PubMed PMID: 31278387.

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Joseph N, Lawson HD, Overholt KJ, Damodaran K, Gottardi R, Acharya AP, Little SR. Synthesis and characterization of CaSr-Metal Organic Frameworks for biodegradable orthopedic applications. Sci Rep. 2019 Sep 10;9(1):13024. doi: 10.1038/s41598-019-49536-9. PubMed PMID: 31506530; PubMed Central PMCID: PMC6736967.

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Di Gesù R, Acharya AP, Jacobs I, Gottardi R. 3D printing for tissue engineering in otolaryngology. Connect Tissue Res. 2020 Mar;61(2):117-136. doi: 10.1080/03008207.2019.1663837. Epub 2019 Sep 16. Review. PubMed PMID: 31524001.

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Rothrauff BB, Sasaki H, Kihara S, Overholt KJ, Gottardi R, Lin H, Fu FH, Tuan RS, Alexander PG. Point-of-Care Procedure for Enhancement of Meniscal Healing in a Goat Model Utilizing Infrapatellar Fat Pad-Derived Stromal Vascular Fraction Cells Seeded in Photocrosslinkable Hydrogel. Am J Sports Med. 2019 Dec;47(14):3396-3405. doi: 10.1177/0363546519880468. Epub 2019 Oct 23. PubMed PMID: 31644307.

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Lapomarda A, De Acutis A, Chiesa I, Fortunato GM, Montemurro F, De Maria C, Mattioli Belmonte M, Gottardi R, Vozzi G. Pectin-GPTMS-Based Biomaterial: toward a Sustainable Bioprinting of 3D scaffolds for Tissue Engineering Application. Biomacromolecules. 2020 Feb 10;21(2):319-327. doi: 10.1021/acs.biomac.9b01332. Epub 2019 Dec 17. PubMed PMID: 31808680.