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Stein A, Voigt W, Jordan K. Chemotherapy-induced diarrhea: pathophysiology, frequency and guideline-based management. Ther Adv Med Oncol. 2010 Jan;2(1):51-63. doi: 10.1177/1758834009355164. PubMed PMID: 21789126; PubMed Central PMCID: PMC3126005.
Peinert S, Grothe W, Stein A, Müller LP, Ruessel J, Voigt W, Schmoll HJ, Arnold D. Safety and efficacy of weekly 5-fluorouracil/folinic acid/oxaliplatin/irinotecan in the first-line treatment of gastrointestinal cancer. Ther Adv Med Oncol. 2010 May;2(3):161-74. doi: 10.1177/1758834010365061. PubMed PMID: 21789132; PubMed Central PMCID: PMC3126013.
Stein A, Rüssel J, Peinert S, Arnold D. The role of peri-operative treatment in resectable liver metastases of colorectal cancer. Ther Adv Med Oncol. 2010 Nov;2(6):389-98. doi: 10.1177/1758834010375095. PubMed PMID: 21789150; PubMed Central PMCID: PMC3126028.
Arnold D, Stöltzing O, Timm S, Stein A, Geissler M, Lang H. [Resectable colorectal liver metastases: pro neoadjuvant therapy - contra neoadjuvant therapy]. Z Gastroenterol. 2010 Dec;48(12):1375-83. doi: 10.1055/s-0029-1245715. Epub 2010 Dec 1. PubMed PMID: 21125514.
Jordan K, Jahn F, Jahn P, Behlendorf T, Stein A, Ruessel J, Kegel T, Schmoll HJ. The NK-1 receptor-antagonist aprepitant in high-dose chemotherapy (high-dose melphalan and high-dose T-ICE: paclitaxel, ifosfamide, carboplatin, etoposide): efficacy and safety of a triple antiemetic combination. Bone Marrow Transplant. 2011 Jun;46(6):784-9. doi: 10.1038/bmt.2010.205. Epub 2010 Sep 13. PubMed PMID: 20838387.
Rüssel J, Stein A, Behrmann C, Hauptmann S, Krummenerl P, Schmoll HJ, Arnold D. Inflammatory lesions of the peritoneum mimic carcinomatosis after treatment with intravenous chemotherapy and intraperitoneal catumaxomab. J Clin Oncol. 2011 Aug 1;29(22):e644-6. doi: 10.1200/JCO.2010.34.3939. Epub 2011 May 23. PubMed PMID: 21606410.
Stein A, Atanackovic D, Bokemeyer C. Current standards and new trends in the primary treatment of colorectal cancer. Eur J Cancer. 2011 Sep;47 Suppl 3:S312-4. doi: 10.1016/S0959-8049(11)70183-6. Review. PubMed PMID: 21943995.
Stein A, Hiemer S, Schmoll HJ. Adjuvant therapy for early colon cancer: current status. Drugs. 2011 Dec 3;71(17):2257-75. doi: 10.2165/11594490-000000000-00000. Review. PubMed PMID: 22085384.
Stein A, Arnold D. Oxaliplatin: a review of approved uses. Expert Opin Pharmacother. 2012 Jan;13(1):125-37. doi: 10.1517/14656566.2012.643870. Review. PubMed PMID: 22149372.
Arnold D, Stein A. Personalized treatment of colorectal cancer. Onkologie. 2012;35 Suppl 1:42-8. doi: 10.1159/000334821. Epub 2012 Jan 20. PubMed PMID: 22286587.
Stein A, Glockzin G, Wienke A, Arnold D, Edelmann T, Hildebrandt B, Hollerbach S, Illerhaus G, Königsrainer A, Richter M, Schlitt HJ, Schmoll HJ. Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature. BMC Cancer. 2012 Aug 16;12:356. doi: 10.1186/1471-2407-12-356. Review. PubMed PMID: 22897915; PubMed Central PMCID: PMC3503684.
Schmoll HJ, Van Cutsem E, Stein A, Valentini V, Glimelius B, Haustermans K, Nordlinger B, van de Velde CJ, Balmana J, Regula J, Nagtegaal ID, Beets-Tan RG, Arnold D, Ciardiello F, Hoff P, Kerr D, Köhne CH, Labianca R, Price T, Scheithauer W, Sobrero A, Tabernero J, Aderka D, Barroso S, Bodoky G, Douillard JY, El Ghazaly H, Gallardo J, Garin A, Glynne-Jones R, Jordan K, Meshcheryakov A, Papamichail D, Pfeiffer P, Souglakos I, Turhal S, Cervantes A. ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making. Ann Oncol. 2012 Oct;23(10):2479-2516. doi: 10.1093/annonc/mds236. PubMed PMID: 23012255.
Quidde J, Arnold D, Stein A. Clinical management of localized colon cancer with capecitabine. Clin Med Insights Oncol. 2012;6:363-73. doi: 10.4137/CMO.S8194. Epub 2012 Nov 5. PubMed PMID: 23170068; PubMed Central PMCID: PMC3498969.
Stein A, Schmoll HJ. Systemic treatment of liver metastases from colorectal cancer. Ther Adv Med Oncol. 2013 May;5(3):193-203. doi: 10.1177/1758834012473347. PubMed PMID: 23634197; PubMed Central PMCID: PMC3630480.
Arnold D, Stein A. New developments in the second-line treatment of metastatic colorectal cancer: potential place in therapy. Drugs. 2013 Jun;73(9):883-91. doi: 10.1007/s40265-013-0076-5. Review. PubMed PMID: 23743737.
Hubert E, Schulte N, Belle S, Gerhardt A, Merx K, Hofmann WK, Stein A, Burkholder I, Hofheinz RD, Kripp M. Cancer patients and advance directives: a survey of patients in a hematology and oncology outpatient clinic. Onkologie. 2013;36(7-8):398-402. doi: 10.1159/000353604. Epub 2013 Jul 8. PubMed PMID: 23921757.
Stein A, Kretzschmar A, Behringer D, Wolff T, Zimber J, Hegewisch-Becker S, Kettner E, Pflüger KH, Kirsch A, Arnold D. Capecitabine and bevacizumab for non-resectable metastatic colorectal cancer patients: final results from phase II AIO KRK 0105 trial. BMC Cancer. 2013 Oct 4;13:454. doi: 10.1186/1471-2407-13-454. PubMed PMID: 24090011; PubMed Central PMCID: PMC3850951.
Stein A, Bokemeyer C. How to select the optimal treatment for first line metastatic colorectal cancer. World J Gastroenterol. 2014 Jan 28;20(4):899-907. doi: 10.3748/wjg.v20.i4.899. Review. PubMed PMID: 24574764; PubMed Central PMCID: PMC3921543.
Schmoll HJ, Stein A. Colorectal cancer in 2013: Towards improved drugs, combinations and patient selection. Nat Rev Clin Oncol. 2014 Feb;11(2):79-80. doi: 10.1038/nrclinonc.2013.254. Epub 2014 Jan 21. Review. PubMed PMID: 24445520.
Burandt E, Schreiber M, Stein A, Minner S, Clauditz TS, Bokemeyer C, Jänicke F, Fisch M, Izbicki JR, Knecht R, Sauter G, Stahl PR. Continuous tissue microarray based identification of cancers with homogeneous target expression for successful targeted therapy in clinical routine practice. Genes Chromosomes Cancer. 2014 Mar;53(3):228-39. doi: 10.1002/gcc.22130. Epub 2013 Dec 5. PubMed PMID: 24311521.
Stein A, Arnold D, Thuss-Patience PC, Moehler M, Grothe W, Seufferlein T, Reinacher-Schick A, Geissler M, Hofheinz RD, Schmoll HJ. Docetaxel, oxaliplatin and capecitabine (TEX regimen) in patients with metastatic gastric or gastro-esophageal cancer: results of a multicenter phase I/II study. Acta Oncol. 2014 Mar;53(3):392-8. doi: 10.3109/0284186X.2013.833346. Epub 2013 Sep 12. PubMed PMID: 24024696.
Jensen W, Baumann FT, Stein A, Bloch W, Bokemeyer C, de Wit M, Oechsle K. Exercise training in patients with advanced gastrointestinal cancer undergoing palliative chemotherapy: a pilot study. Support Care Cancer. 2014 Jul;22(7):1797-806. doi: 10.1007/s00520-014-2139-x. Epub 2014 Feb 15. PubMed PMID: 24531742.
Hofheinz R, Petersen V, Kindler M, Schulze M, Seraphin J, Hoeffkes HG, Valdix AR, Schroeder J, Herrenberger J, Stein A, Hinke A, Arnold D. Bevacizumab in first-line treatment of elderly patients with metastatic colorectal cancer: German community-based observational cohort study results. BMC Cancer. 2014 Oct 13;14:761. doi: 10.1186/1471-2407-14-761. PubMed PMID: 25311943; PubMed Central PMCID: PMC4198800.
Kuehnle MC, Attig S, Britten CM, Schulze-Bergkamen H, Lordick F, von Wichert G, Thuss-Patience P, Stein A, Schuler M, Bassermann F, Sahin U, Türeci O. Phenotyping of peripheral blood mononuclear cells of patients with advanced heavily pre-treated adenocarcinoma of the stomach and gastro-esophageal junction. Cancer Immunol Immunother. 2014 Dec;63(12):1273-84. doi: 10.1007/s00262-014-1596-x. Epub 2014 Aug 28. PubMed PMID: 25164876.
Stein A, Petersen V, Schulze M, Seraphin J, Hoeffkes HG, Valdix AR, Schroeder J, Herrenberger J, Boxberger F, Leutgeb B, Hinke A, Kutscheidt A, Arnold D. Bevacizumab plus chemotherapy as first-line treatment for patients with metastatic colorectal cancer: results from a large German community-based observational cohort study. Acta Oncol. 2015 Feb;54(2):171-8. doi: 10.3109/0284186X.2014.961649. Epub 2014 Oct 13. PubMed PMID: 25307517.
Zinser ME, Salzer HJ, Stein A, von Petersdorff M, Koops A, Holzhüter J. [A 73-year-old female patient after liver and kidney transplantation with dull pain in the epigastrium and recurrent epistaxis]. Internist (Berl). 2015 May;56(5):566-72. doi: 10.1007/s00108-015-3700-5. PubMed PMID: 25874738.
Braig F, März M, Schieferdecker A, Schulte A, Voigt M, Stein A, Grob T, Alawi M, Indenbirken D, Kriegs M, Engel E, Vanhoefer U, Grundhoff A, Loges S, Riecken K, Fehse B, Bokemeyer C, Binder M. Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer. Oncotarget. 2015 May 20;6(14):12035-47. doi: 10.18632/oncotarget.3574. PubMed PMID: 26059438; PubMed Central PMCID: PMC4494921.
Stein A, Arnold D, Bridgewater J, Goldstein D, Jensen LH, Klümpen HJ, Lohse AW, Nashan B, Primrose J, Schrum S, Shannon J, Vettorazzi E, Wege H. Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma (ACTICCA-1 trial) - a randomized, multidisciplinary, multinational phase III trial. BMC Cancer. 2015 Jul 31;15:564. doi: 10.1186/s12885-015-1498-0. PubMed PMID: 26228433; PubMed Central PMCID: PMC4520064.
Stein A, Atanackovic D, Hildebrandt B, Stübs P, Brugger W, Hapke G, Steffens CC, Illerhaus G, Bluemner E, Stöhlmacher J, Bokemeyer C. Upfront FOLFOXIRI+bevacizumab followed by fluoropyrimidin and bevacizumab maintenance in patients with molecularly unselected metastatic colorectal cancer. Br J Cancer. 2015 Sep 15;113(6):872-7. doi: 10.1038/bjc.2015.299. Epub 2015 Sep 3. PubMed PMID: 26335608; PubMed Central PMCID: PMC4578090.
Bokemeyer C, Stein A, Ridwelski K, Atanackovic D, Arnold D, Wöll E, Ulrich A, Fischer R, Krüger C, Schuhmacher C. A phase II study of catumaxomab administered intra- and postoperatively as part of a multimodal approach in primarily resectable gastric cancer. Gastric Cancer. 2015 Oct;18(4):833-42. doi: 10.1007/s10120-014-0423-6. Epub 2014 Sep 12. PubMed PMID: 25214034.
Farschtschi S, Kollmann P, Dalchow C, Stein A, Mautner VF. Reduced dosage of bevacizumab in treatment of vestibular schwannomas in patients with neurofibromatosis type 2. Eur Arch Otorhinolaryngol. 2015 Dec;272(12):3857-60. doi: 10.1007/s00405-015-3604-y. Epub 2015 Mar 21. PubMed PMID: 25794543.
Stein A, Quidde J, Schröder JK, Göhler T, Tschechne B, Valdix AR, Höffkes HG, Schirrmacher-Memmel S, Wohlfarth T, Hinke A, Engelen A, Arnold D. Capecitabine in the routine first-line treatment of elderly patients with advanced colorectal cancer--results from a non-interventional observation study. BMC Cancer. 2016 Feb 10;16:82. doi: 10.1186/s12885-016-2113-8. PubMed PMID: 26865161; PubMed Central PMCID: PMC4750193.
Creutzfeldt A, Suling A, Oechsle K, Mehnert A, Atanackovic D, Kripp M, Arnold D, Stein A, Quidde J. Integrating patient reported measures as predictive parameters into decisionmaking about palliative chemotherapy: a pilot study. BMC Palliat Care. 2016 Mar 1;15:25. doi: 10.1186/s12904-016-0101-z. PubMed PMID: 26928745; PubMed Central PMCID: PMC4772352.
Quidde J, Azémar M, Bokemeyer C, Arnold D, Stein A. Treatment approach in patients with hyperbilirubinemia secondary to liver metastases in gastrointestinal malignancies: a case series and review of literature. Ther Adv Med Oncol. 2016 May;8(3):144-52. doi: 10.1177/1758834016637585. Epub 2016 Mar 17. PubMed PMID: 27239232; PubMed Central PMCID: PMC4872252.
Gorges TM, Stein A, Quidde J, Hauch S, Röck K, Riethdorf S, Joosse SA, Pantel K. Improved Detection of Circulating Tumor Cells in Metastatic Colorectal Cancer by the Combination of the CellSearch® System and the AdnaTest®. PLoS One. 2016;11(5):e0155126. doi: 10.1371/journal.pone.0155126. eCollection 2016. PubMed PMID: 27182774; PubMed Central PMCID: PMC4868337.
Loupakis F, Stein A, Ychou M, Hermann F, Salud A, Österlund P. A Review of Clinical Studies and Practical Guide for the Administration of Triplet Chemotherapy Regimens with Bevacizumab in First-line Metastatic Colorectal Cancer. Target Oncol. 2016 Jun;11(3):293-308. doi: 10.1007/s11523-015-0400-y. Review. PubMed PMID: 26687849; PubMed Central PMCID: PMC4901088.
Stein A, Schwenke C, Folprecht G, Arnold D. Effect of Application and Intensity of Bevacizumab-based Maintenance After Induction Chemotherapy With Bevacizumab for Metastatic Colorectal Cancer: A Meta-analysis. Clin Colorectal Cancer. 2016 Jun;15(2):e29-39. doi: 10.1016/j.clcc.2015.12.005. Epub 2015 Dec 18. PubMed PMID: 26781523.
Hvichia GE, Parveen Z, Wagner C, Janning M, Quidde J, Stein A, Müller V, Loges S, Neves RP, Stoecklein NH, Wikman H, Riethdorf S, Pantel K, Gorges TM. A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells. Int J Cancer. 2016 Jun 15;138(12):2894-904. doi: 10.1002/ijc.30007. Epub 2016 Feb 26. PubMed PMID: 26789903; PubMed Central PMCID: PMC5069649.
Tachezy M, Gebauer F, Janot M, Uhl W, Zerbi A, Montorsi M, Perinel J, Adham M, Dervenis C, Agalianos C, Malleo G, Maggino L, Stein A, Izbicki JR, Bockhorn M. Synchronous resections of hepatic oligometastatic pancreatic cancer: Disputing a principle in a time of safe pancreatic operations in a retrospective multicenter analysis. Surgery. 2016 Jul;160(1):136-144. doi: 10.1016/j.surg.2016.02.019. Epub 2016 Apr 3. PubMed PMID: 27048934.
Quidde J, von Grundherr J, Koch B, Bokemeyer C, Escherich G, Valentini L, Buchholz D, Schilling G, Stein A. Improved nutrition in adolescents and young adults after childhood cancer - INAYA study. BMC Cancer. 2016 Nov 8;16(1):872. doi: 10.1186/s12885-016-2896-7. PubMed PMID: 27825320; PubMed Central PMCID: PMC5101649.
Quidde J, Denne L, Kutscheidt A, Kindler M, Kirsch A, Kripp M, Petersen V, Schulze M, Seraphin J, Tummes D, Arnold D, Stein A. Baseline and On-Treatment Markers Determining Prognosis of First-Line Chemotherapy in Combination with Bevacizumab in Patients with Metastatic Colorectal Cancer. Oncol Res Treat. 2017;40(1-2):21-26. doi: 10.1159/000454774. Epub 2017 Jan 18. PubMed PMID: 28192780.
Schrader J, Henes FO, Perez D, Burdak-Rothkamm S, Stein A, Izbicki JR, Lohse AW. Successful mTOR inhibitor therapy for a metastastic neuroendocrine tumour in a patient with a germline TSC2 mutation. Ann Oncol. 2017 Apr 1;28(4):904-905. doi: 10.1093/annonc/mdx007. PubMed PMID: 28327903.
Akyüz N, Brandt A, Stein A, Schliffke S, Mährle T, Quidde J, Goekkurt E, Loges S, Haalck T, Ford CT, Asemissen AM, Thiele B, Radloff J, Thenhausen T, Krohn-Grimberghe A, Bokemeyer C, Binder M. T-cell diversification reflects antigen selection in the blood of patients on immune checkpoint inhibition and may be exploited as liquid biopsy biomarker. Int J Cancer. 2017 Jun 1;140(11):2535-2544. doi: 10.1002/ijc.30549. Epub 2017 Mar 6. PubMed PMID: 27925177.
Kripp M, Prasnikar N, Vehling-Kaiser U, Quidde J, Al-Batran SE, Stein A, Neben K, Hannig CV, Tessen HW, Trarbach T, Hinke A, Hofheinz RD. AIO LQ-0110: a randomized phase II trial comparing oral doxycycline versus local administration of erythromycin as preemptive treatment strategies of panitumumab-mediated skin toxicity in patients with metastatic colorectal cancer. Oncotarget. 2017 Dec 1;8(62):105061-105071. doi: 10.18632/oncotarget.21249. eCollection 2017 Dec 1. PubMed PMID: 29285233; PubMed Central PMCID: PMC5739620.
Arnold D, Prager GW, Quintela A, Stein A, Moreno Vera S, Mounedji N, Taieb J. Beyond second-line therapy in patients with metastatic colorectal cancer: a systematic review. Ann Oncol. 2018 Apr 1;29(4):835-856. doi: 10.1093/annonc/mdy038. PubMed PMID: 29452346; PubMed Central PMCID: PMC5913602.
Stein A, Folprecht G. Immunotherapy of Colon Cancer. Oncol Res Treat. 2018;41(5):282-285. doi: 10.1159/000488918. Epub 2018 Apr 26. PubMed PMID: 29705788.
Quidde J, Pan Y, Salm M, Hendi A, Nilsson S, Oechsle K, Stein A, Nestoriuc Y. Preventing adverse events of chemotherapy by educating patients about the nocebo effect (RENNO study) - study protocol of a randomized controlled trial with gastrointestinal cancer patients. BMC Cancer. 2018 Sep 24;18(1):916. doi: 10.1186/s12885-018-4814-7. PubMed PMID: 30249191; PubMed Central PMCID: PMC6154808.
Stein A, Moehler M, Trojan J, Goekkurt E, Vogel A. Immuno-oncology in GI tumours: Clinical evidence and emerging trials of PD-1/PD-L1 antagonists. Crit Rev Oncol Hematol. 2018 Oct;130:13-26. doi: 10.1016/j.critrevonc.2018.07.001. Epub 2018 Jul 11. Review. PubMed PMID: 30196908.
Samsen A, von der Heyde S, Bokemeyer C, David KA, Flath B, Graap M, Grebenstein B, Heflik L, Hollburg W, Layer P, von Leitner E, Overkamp F, Saeger W, Schneider S, von Seydewitz CU, Stang A, Stein A, Zornig C, Juhl H. Multi-omic based molecular profiling of advanced cancer identifies treatable targets and improves survival in individual patients. Oncotarget. 2018 Oct 5;9(78):34794-34809. doi: 10.18632/oncotarget.26198. eCollection 2018 Oct 5. PubMed PMID: 30410678; PubMed Central PMCID: PMC6205171.
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