Near-infrared fluorescence imaging and histology confirm anomalous edematous signal distribution detected in the rat lung by MRI after allergen challenge.
J Magn Reson Imaging.
2004 Dec;20(6):967-74. doi: 10.1002/jmri.20203. PubMed PMID:
15558573.
Effects of endotoxin and allergen alone and in combination on the sensitivity of the rat airways to adenosine.
Auton Autacoid Pharmacol.
2005 Oct;25(4):167-70. doi: 10.1111/j.1474-8673.2005.00346.x. PubMed PMID:
16176448.
Identification with MRI of the pleura as a major site of the acute inflammatory effects induced by ovalbumin and endotoxin challenge in the airways of the rat.
Am J Physiol Lung Cell Mol Physiol.
2006 Oct;291(4):L651-7. doi: 10.1152/ajplung.00303.2005. Epub 2006 May 25. PubMed PMID:
16728527.
Lung inflammation and vascular remodeling after repeated allergen challenge detected noninvasively by MRI.
Am J Physiol Lung Cell Mol Physiol.
2007 Mar;292(3):L644-53. doi: 10.1152/ajplung.00122.2006. Epub 2006 Nov 3. PubMed PMID:
17085517.
Proton MRI as a noninvasive tool to assess elastase-induced lung damage in spontaneously breathing rats.
Magn Reson Med.
2006 Dec;56(6):1242-50. doi: 10.1002/mrm.21051. PubMed PMID:
17029230.
Capsaicin-induced mucus secretion in rat airways assessed in vivo and non-invasively by magnetic resonance imaging.
Br J Pharmacol.
2007 Apr;150(8):1022-30. doi: 10.1038/sj.bjp.0707168. Epub 2007 Mar 12. PubMed PMID:
17351665; PubMed Central PMCID:
PMC2013907.
In vivo mouse imaging and spectroscopy in drug discovery.
NMR Biomed.
2007 May;20(3):154-85. doi: 10.1002/nbm.1153. Review. PubMed PMID:
17451175.
Bleomycin-induced lung injury assessed noninvasively and in spontaneously breathing rats by proton MRI.
J Magn Reson Imaging.
2007 Oct;26(4):941-9. doi: 10.1002/jmri.21100. PubMed PMID:
17896392.
Lung MRI for experimental drug research.
Eur J Radiol.
2007 Dec;64(3):381-96. doi: 10.1016/j.ejrad.2007.08.012. Epub 2007 Oct 10. Review. PubMed PMID:
17931813.
In vivo pharmacological evaluation of compound 48/80-induced airways oedema by MRI.
Br J Pharmacol.
2008 Jul;154(5):1063-72. doi: 10.1038/bjp.2008.174. Epub 2008 May 12. PubMed PMID:
18469845; PubMed Central PMCID:
PMC2451044.
Allergen-induced lung inflammation in actively sensitized mice assessed with MR imaging.
Radiology.
2008 Sep;248(3):834-43. doi: 10.1148/radiol.2482071452. Epub 2008 Jul 22. PubMed PMID:
18647843.
Time course of airway remodelling after an acute chlorine gas exposure in mice.
Respir Res.
2008 Aug 14;9(1):61. doi: 10.1186/1465-9921-9-61. PubMed PMID:
18702818; PubMed Central PMCID:
PMC2531104.
In vivo assessments of mucus dynamics in the rat lung using a Gd-Cy5.5-bilabeled contrast agent for magnetic resonance and optical imaging.
Magn Reson Med.
2009 Nov;62(5):1164-74. doi: 10.1002/mrm.22130. PubMed PMID:
19780168.
Sustained steroid release in pulmonary inflammation model.
Biomaterials.
2010 Aug;31(23):6050-9. doi: 10.1016/j.biomaterials.2010.04.025. Epub 2010 May 15. PubMed PMID:
20472285.
Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma.
Respir Res.
2010 Oct 6;11(1):138. doi: 10.1186/1465-9921-11-138. PubMed PMID:
20925946; PubMed Central PMCID:
PMC2965137.
Distinct roles for the A2B adenosine receptor in acute and chronic stages of bleomycin-induced lung injury.
J Immunol.
2011 Jan 15;186(2):1097-106. doi: 10.4049/jimmunol.1002907. Epub 2010 Dec 13. PubMed PMID:
21149612; PubMed Central PMCID:
PMC3607290.
Interleukin-6 contributes to inflammation and remodeling in a model of adenosine mediated lung injury.
PLoS One.
2011;6(7):e22667. doi: 10.1371/journal.pone.0022667. Epub 2011 Jul 25. PubMed PMID:
21799929; PubMed Central PMCID:
PMC3143181.
Treatment with a sphingosine-1-phosphate analog inhibits airway remodeling following repeated allergen exposure.
Am J Physiol Lung Cell Mol Physiol.
2012 Apr 15;302(8):L736-45. doi: 10.1152/ajplung.00050.2011. Epub 2012 Jan 27. PubMed PMID:
22287614.
The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease.
FASEB J.
2012 Jun;26(6):2546-57. doi: 10.1096/fj.11-200907. Epub 2012 Mar 13. PubMed PMID:
22415303; PubMed Central PMCID:
PMC3650483.
Immunomodulatory effects of feeding with Bifidobacterium longum on allergen-induced lung inflammation in the mouse.
Pulm Pharmacol Ther.
2012 Aug;25(4):325-34. doi: 10.1016/j.pupt.2012.05.011. Epub 2012 Jun 13. PubMed PMID:
22705947.
Adenosine signaling during acute and chronic disease states.
J Mol Med (Berl).
2013 Feb;91(2):173-81. doi: 10.1007/s00109-013-0997-1. Epub 2013 Jan 23. Review. PubMed PMID:
23340998; PubMed Central PMCID:
PMC3606047.
Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease.
FASEB J.
2013 May;27(5):2013-26. doi: 10.1096/fj.12-222067. Epub 2013 Feb 7. PubMed PMID:
23392349; PubMed Central PMCID:
PMC4046114.
Adenosine A2B receptor and hyaluronan modulate pulmonary hypertension associated with chronic obstructive pulmonary disease.
Am J Respir Cell Mol Biol.
2013 Dec;49(6):1038-47. doi: 10.1165/rcmb.2013-0089OC. PubMed PMID:
23855769; PubMed Central PMCID:
PMC5459551.
Muc5b is required for airway defence.
Nature.
2014 Jan 16;505(7483):412-6. doi: 10.1038/nature12807. Epub 2013 Dec 8. PubMed PMID:
24317696; PubMed Central PMCID:
PMC4001806.
Effect of antigen sensitization and challenge on oscillatory mechanics of the lung and pulmonary inflammation in obese carboxypeptidase E-deficient mice.
Am J Physiol Regul Integr Comp Physiol.
2014 Sep 15;307(6):R621-33. doi: 10.1152/ajpregu.00205.2014. Epub 2014 Jul 9. PubMed PMID:
25009214; PubMed Central PMCID:
PMC4166760.
Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis.
J Immunol.
2014 Oct 1;193(7):3755-68. doi: 10.4049/jimmunol.1302470. Epub 2014 Aug 29. PubMed PMID:
25172494; PubMed Central PMCID:
PMC4169999.
Adenosine promotes vascular barrier function in hyperoxic lung injury.
Physiol Rep.
2014 Sep 1;2(9). doi: 10.14814/phy2.12155. Print 2014 Sep 1. PubMed PMID:
25263205; PubMed Central PMCID:
PMC4270235.
Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension.
FASEB J.
2015 Jan;29(1):50-60. doi: 10.1096/fj.14-260182. Epub 2014 Oct 15. PubMed PMID:
25318478; PubMed Central PMCID:
PMC4763976.
Hypoxia-induced deoxycytidine kinase contributes to epithelial proliferation in pulmonary fibrosis.
Am J Respir Crit Care Med.
2014 Dec 15;190(12):1402-12. doi: 10.1164/rccm.201404-0744OC. PubMed PMID:
25358054; PubMed Central PMCID:
PMC4299646.
Alveolar Epithelial A2B Adenosine Receptors in Pulmonary Protection during Acute Lung Injury.
J Immunol.
2015 Aug 15;195(4):1815-24. doi: 10.4049/jimmunol.1401957. Epub 2015 Jul 17. PubMed PMID:
26188061; PubMed Central PMCID:
PMC4530072.
STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation.
FASEB J.
2016 Jan;30(1):129-40. doi: 10.1096/fj.15-273953. Epub 2015 Aug 31. PubMed PMID:
26324850; PubMed Central PMCID:
PMC4684532.
Extracellular adenosine levels are associated with the progression and exacerbation of pulmonary fibrosis.
FASEB J.
2016 Feb;30(2):874-83. doi: 10.1096/fj.15-274845. Epub 2015 Nov 2. PubMed PMID:
26527068; PubMed Central PMCID:
PMC4714555.
Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung Fibrosis.
Cancer Res.
2016 May 15;76(10):3045-56. doi: 10.1158/0008-5472.CAN-15-2310. Epub 2016 Feb 26. PubMed PMID:
26921334; PubMed Central PMCID:
PMC4960984.
Altered Hypoxic-Adenosine Axis and Metabolism in Group III Pulmonary Hypertension.
Am J Respir Cell Mol Biol.
2016 Apr;54(4):574-83. doi: 10.1165/rcmb.2015-0145OC. PubMed PMID:
26414702; PubMed Central PMCID:
PMC4821053.
Sustained Elevated Adenosine via ADORA2B Promotes Chronic Pain through Neuro-immune Interaction.
Cell Rep.
2016 Jun 28;16(1):106-119. doi: 10.1016/j.celrep.2016.05.080. Epub 2016 Jun 16. PubMed PMID:
27320922; PubMed Central PMCID:
PMC5662192.
Macrophage bone morphogenic protein receptor 2 depletion in idiopathic pulmonary fibrosis and Group III pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol.
2016 Aug 1;311(2):L238-54. doi: 10.1152/ajplung.00142.2016. Epub 2016 Jun 17. PubMed PMID:
27317687; PubMed Central PMCID:
PMC6425517.
Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia.
Circulation.
2016 Aug 2;134(5):405-21. doi: 10.1161/CIRCULATIONAHA.116.021311. PubMed PMID:
27482003; PubMed Central PMCID:
PMC6168195.
Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent.
Nat Commun.
2017 Feb 7;8:14108. doi: 10.1038/ncomms14108. PubMed PMID:
28169986; PubMed Central PMCID:
PMC5309698.
Pulmonary Hypertension Associated with Idiopathic Pulmonary Fibrosis: Current and Future Perspectives.
Can Respir J.
2017;2017:1430350. doi: 10.1155/2017/1430350. Epub 2017 Feb 13. Review. PubMed PMID:
28286407; PubMed Central PMCID:
PMC5327768.
Rapamycin nanoparticles localize in diseased lung vasculature and prevent pulmonary arterial hypertension.
Int J Pharm.
2017 May 30;524(1-2):257-267. doi: 10.1016/j.ijpharm.2017.03.069. Epub 2017 Mar 28. PubMed PMID:
28359821.
Use of airway epithelial cell culture to unravel the pathogenesis and study treatment in obstructive airway diseases.
Pulm Pharmacol Ther.
2017 Aug;45:101-113. doi: 10.1016/j.pupt.2017.05.008. Epub 2017 May 11. Review. PubMed PMID:
28502841.
The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease.
Oncotarget.
2017 May 30;8(22):35962-35972. doi: 10.18632/oncotarget.16414. PubMed PMID:
28415591; PubMed Central PMCID:
PMC5482630.
HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis.
FASEB J.
2017 Nov;31(11):4745-4758. doi: 10.1096/fj.201700219R. Epub 2017 Jul 12. PubMed PMID:
28701304; PubMed Central PMCID:
PMC5636704.
Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis.
Br J Pharmacol.
2017 Oct;174(19):3284-3301. doi: 10.1111/bph.13947. Epub 2017 Aug 17. PubMed PMID:
28688167; PubMed Central PMCID:
PMC5595757.
P2Y(6) Receptor Activation Promotes Inflammation and Tissue Remodeling in Pulmonary Fibrosis.
Front Immunol.
2017;8:1028. doi: 10.3389/fimmu.2017.01028. eCollection 2017. PubMed PMID:
28878780; PubMed Central PMCID:
PMC5572280.
Loss of CD73-mediated extracellular adenosine production exacerbates inflammation and abnormal alveolar development in newborn mice exposed to prolonged hyperoxia.
Pediatr Res.
2017 Aug 23;. doi: 10.1038/pr.2017.176. [Epub ahead of print] PubMed PMID:
28832580.
Early Career Members at the ERS International Congress 2017: highlights from the Assemblies.
Breathe (Sheff).
2017 Dec;13(4):e121-e129. doi: 10.1183/20734735.017617. PubMed PMID:
29928461; PubMed Central PMCID:
PMC6003269.
Transforming Growth Factor-β and Bone Morphogenetic Protein 2 Regulation of MicroRNA-200 Family in Chronic Pancreatitis.
Pancreas.
2018 Feb;47(2):252-256. doi: 10.1097/MPA.0000000000000980. PubMed PMID:
29303912; PubMed Central PMCID:
PMC5776736.
Comprehensive Characterization of Alternative Polyadenylation in Human Cancer.
J Natl Cancer Inst.
2018 Apr 1;110(4):379-389. doi: 10.1093/jnci/djx223. PubMed PMID:
29106591; PubMed Central PMCID:
PMC6059203.
Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension.
Front Physiol.
2018;9:555. doi: 10.3389/fphys.2018.00555. eCollection 2018. PubMed PMID:
29910735; PubMed Central PMCID:
PMC5992271.
What would you like to do?