My Bibliography

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Holloway JK, Mohan S, Balmus G, Sun X, Modzelewski A, Borst PL, Freire R, Weiss RS, Cohen PE. Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis. PLoS Genet. 2011 Jun;7(6):e1002094. doi: 10.1371/journal.pgen.1002094. Epub 2011 Jun 2. PubMed PMID: 21655083; PubMed Central PMCID: PMC3107204.

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Modzelewski AJ, Holmes RJ, Hilz S, Grimson A, Cohen PE. AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline. Dev Cell. 2012 Aug 14;23(2):251-64. doi: 10.1016/j.devcel.2012.07.003. Epub 2012 Aug 2. PubMed PMID: 22863743; PubMed Central PMCID: PMC3470808.

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Lyndaker AM, Modzelewski AJ, Welsh IC. Reproductive and developmental genomics retreat at Cornell University, 2012. Mol Reprod Dev. 2012 Sep;79(9):588-91. doi: 10.1002/mrd.22081. Epub 2012 Aug 29. Review. PubMed PMID: 22933246; PubMed Central PMCID: PMC4104196.

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Zhang J, Bonasio R, Strino F, Kluger Y, Holloway JK, Modzelewski AJ, Cohen PE, Reinberg D. SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors. Genes Dev. 2013 Apr 1;27(7):749-66. doi: 10.1101/gad.210963.112. PubMed PMID: 23592795; PubMed Central PMCID: PMC3639416.

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Modzelewski AJ, Hilz S, Crate EA, Schweidenback CT, Fogarty EA, Grenier JK, Freire R, Cohen PE, Grimson A. Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males. J Cell Sci. 2015 Jun 15;128(12):2314-27. doi: 10.1242/jcs.167148. Epub 2015 May 1. PubMed PMID: 25934699; PubMed Central PMCID: PMC4487015.

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Sun X, Brieño-Enríquez MA, Cornelius A, Modzelewski AJ, Maley TT, Campbell-Peterson KM, Holloway JK, Cohen PE. FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice. Chromosoma. 2016 Jun;125(2):237-52. doi: 10.1007/s00412-015-0549-2. Epub 2015 Oct 21. PubMed PMID: 26490168; PubMed Central PMCID: PMC5415080.

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Chen S, Lee B, Lee AY, Modzelewski AJ, He L. Highly Efficient Mouse Genome Editing by CRISPR Ribonucleoprotein Electroporation of Zygotes. J Biol Chem. 2016 Jul 8;291(28):14457-67. doi: 10.1074/jbc.M116.733154. Epub 2016 May 5. PubMed PMID: 27151215; PubMed Central PMCID: PMC4938170.

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Hilz S, Modzelewski AJ, Cohen PE, Grimson A. The roles of microRNAs and siRNAs in mammalian spermatogenesis. Development. 2016 Sep 1;143(17):3061-73. doi: 10.1242/dev.136721. Review. PubMed PMID: 27578177; PubMed Central PMCID: PMC5047671.

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Hilz S, Fogarty EA, Modzelewski AJ, Cohen PE, Grimson A. Transcriptome profiling of the developing male germ line identifies the miR-29 family as a global regulator during meiosis. RNA Biol. 2017 Feb;14(2):219-235. doi: 10.1080/15476286.2016.1270002. Epub 2016 Dec 16. PubMed PMID: 27981880; PubMed Central PMCID: PMC5324742.

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Modzelewski AJ, Chen S, Willis BJ, Lloyd KCK, Wood JA, He L. Efficient mouse genome engineering by CRISPR-EZ technology. Nat Protoc. 2018 Jun;13(6):1253-1274. doi: 10.1038/nprot.2018.012. Epub 2018 May 10. PubMed PMID: 29748649; PubMed Central PMCID: PMC6296855.

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Tsitsiklis A, Bangs DJ, Lutes LK, Chan SW, Geiger KM, Modzelewski AJ, Labarta-Bajo L, Wang Y, Zuniga EI, Dai S, Robey EA. An Unusual MHC Molecule Generates Protective CD8+ T Cell Responses to Chronic Infection. Front Immunol. 2020;11:1464. doi: 10.3389/fimmu.2020.01464. eCollection 2020. PubMed PMID: 32733483; PubMed Central PMCID: PMC7360836.

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Rosàs-Canyelles E, Modzelewski AJ, Geldert A, He L, Herr AE. Multimodal detection of protein isoforms and nucleic acids from mouse pre-implantation embryos. Nat Protoc. 2021 Feb;16(2):1062-1088. doi: 10.1038/s41596-020-00449-2. Epub 2021 Jan 15. PubMed PMID: 33452502; PubMed Central PMCID: PMC7954398.

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Modzelewski A, Shao W, Chen J, Lee A, Qi X, Noon M, Tjokro K, Sales G, Biton A, Speed T, Xuan Z, Wang T, Risso D, He L. A species-specific retrotransposon drives a conserved <i>Cdk2ap1</i> isoform essential for preimplantation development. [Preprint]. 2021 March. doi: 10.1101/2021.03.24.436683.

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Rosàs-Canyelles E, Modzelewski AJ, Gomez Martinez AE, Geldert A, Gopal A, He L, Herr AE. Multimodal detection of protein isoforms and nucleic acids from low starting cell numbers. Lab Chip. 2021 Jun 15;21(12):2427-2436. doi: 10.1039/d1lc00073j. PubMed PMID: 33978041; PubMed Central PMCID: PMC8206029.

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Björkgren I, Chung DH, Mendoza S, Gabelev-Khasin L, Petersen NT, Modzelewski A, He L, Lishko PV. Alpha/Beta Hydrolase Domain-Containing Protein 2 Regulates the Rhythm of Follicular Maturation and Estrous Stages of the Female Reproductive Cycle. Front Cell Dev Biol. 2021;9:710864. doi: 10.3389/fcell.2021.710864. eCollection 2021. PubMed PMID: 34568325; PubMed Central PMCID: PMC8455887.

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Modzelewski AJ, Shao W, Chen J, Lee A, Qi X, Noon M, Tjokro K, Sales G, Biton A, Anand A, Speed TP, Xuan Z, Wang T, Risso D, He L. A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development. Cell. 2021 Oct 28;184(22):5541-5558.e22. doi: 10.1016/j.cell.2021.09.021. Epub 2021 Oct 12. PubMed PMID: 34644528; PubMed Central PMCID: PMC8787082.

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Modzelewski AJ, Gan Chong J, Wang T, He L. Mammalian genome innovation through transposon domestication. Nat Cell Biol. 2022 Sep;24(9):1332-1340. doi: 10.1038/s41556-022-00970-4. Epub 2022 Aug 25. Review. PubMed PMID: 36008480; PubMed Central PMCID: PMC9729749.

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Diallo CK, Modzelewski AJ. Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes. J Vis Exp. 2022 Dec 16;(190). doi: 10.3791/64302. PubMed PMID: 36591999; PubMed Central PMCID: PMC13186264.

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Guo Y, Li TD, Modzelewski AJ, Siomi H. Retrotransposon renaissance in early embryos. Trends Genet. 2024 Jan;40(1):39-51. doi: 10.1016/j.tig.2023.10.010. Epub 2023 Nov 8. Review. PubMed PMID: 37949723; PubMed Central PMCID: PMC12123636.

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Basavaraja R, Zhang H, Holczbauer Á, Lu Z, Radaelli E, Assenmacher CA, George SS, Nallamala VC, Beiting DP, Meyer-Ficca ML, Meyer RG, Guo W, Fan Y, Modzelewski AJ, Spiegelman VS, Cohen MS, Fuchs SY. PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies. Cell Rep Med. 2024 Jul 16;5(7):101649. doi: 10.1016/j.xcrm.2024.101649. PubMed PMID: 39019005; PubMed Central PMCID: PMC11293321.

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Li TD, Toohill K, Modzelewski AJ. From Junk DNA to Genomic Treasure: Impacts of Transposable Element DNA, RNA, and Protein in Mammalian Development and Disease. Wiley Interdiscip Rev RNA. 2025 Jul-Aug;16(4):e70022. doi: 10.1002/wrna.70022. Review. PubMed PMID: 40804709; PubMed Central PMCID: PMC12350819.

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Guo Y, Modzelewski AJ. A retrotransposon caught red-handed in a curious case of missing digits. Nat Genet. 2025 Jul;57(7):1571-1573. doi: 10.1038/s41588-025-02147-9. PubMed PMID: 40634705.

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Kang Z, Guo R, Han S, Yang F, Zhang J, Wang Y, Nelson KA, Nallamala VC, Leu NA, Li Z, Liu J, Liang H, Lan Y, Faustino A, Tang HY, Modzelewski AJ, Ye L, Wang PJ. Stage-dependent dual mechanisms of MORC2 in retrotransposon silencing and sex chromosome inactivation in germ cells. Nucleic Acids Res. 2025 Nov 26;53(22). doi: 10.1093/nar/gkaf1362. PubMed PMID: 41414675; PubMed Central PMCID: PMC12714561.