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Li ZB, Pu L. BINOL-Salen-catalyzed highly enantioselective alkyne additions to aromatic aldehydes. Org Lett. 2004 Mar 18;6(6):1065-8. doi: 10.1021/ol0498139. PubMed PMID: 15012101.
Li ZB, Lin J, Zhang HC, Sabat M, Hyacinth M, Pu L. Macrocyclic bisbinaphthyl fluorophores and their acyclic analogues: signal amplification and chiral recognition. J Org Chem. 2004 Sep 17;69(19):6284-93. doi: 10.1021/jo049366a. PubMed PMID: 15357587.
Li ZB, Lin J, Pu L. A cyclohexyl-1,2-diamine-derived bis(binaphthyl) macrocycle: enhanced sensitivity and enantioselectivity in the fluorescent recognition of mandelic acid. Angew Chem Int Ed Engl. 2005 Mar 4;44(11):1690-3. doi: 10.1002/anie.200462471. PubMed PMID: 15688352.
Li ZB, Lin J, Qin YC, Pu L. Enantioselective fluorescent recognition of a soluble "supported" chiral acid: toward a new method for chiral catalyst screening. Org Lett. 2005 Aug 4;7(16):3441-4. doi: 10.1021/ol0510163. PubMed PMID: 16048312.
Cai W, Hsu AR, Li ZB, Chen X. Are quantum dots ready for in vivo imaging in human subjects?. Nanoscale Res Lett. 2007 Jun;2(6):265-281. doi: 10.1007/s11671-007-9061-9. PubMed PMID: 21394238; PubMed Central PMCID: PMC3050636.
Li ZB, Liu TD, Pu L. Chiral macrocycle-catalyzed highly enantioselective phenylacetylene addition to aliphatic and vinyl aldehydes. J Org Chem. 2007 Jun 8;72(12):4340-3. doi: 10.1021/jo070091j. Epub 2007 May 11. PubMed PMID: 17497801.
Li ZB, Lin J, Sabat M, Hyacinth M, Pu L. Enantioselective fluorescent recognition of chiral acids by cyclohexane-1,2-diamine-based bisbinaphthyl molecules. J Org Chem. 2007 Jun 22;72(13):4905-16. doi: 10.1021/jo0704715. Epub 2007 May 27. PubMed PMID: 17530897; PubMed Central PMCID: PMC2536617.
Li ZB, Cai W, Cao Q, Chen K, Wu Z, He L, Chen X. (64)Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor alpha(v)beta(3) integrin expression. J Nucl Med. 2007 Jul;48(7):1162-71. doi: 10.2967/jnumed.107.039859. Epub 2007 Jun 15. PubMed PMID: 17574975.
Wu Z, Li ZB, Chen K, Cai W, He L, Chin FT, Li F, Chen X. microPET of tumor integrin alphavbeta3 expression using 18F-labeled PEGylated tetrameric RGD peptide (18F-FPRGD4). J Nucl Med. 2007 Sep;48(9):1536-44. doi: 10.2967/jnumed.107.040816. Epub 2007 Aug 17. PubMed PMID: 17704249; PubMed Central PMCID: PMC4183663.
Wang J, Yang CT, Kim YS, Sreerama SG, Cao Q, Li ZB, He Z, Chen X, Liu S. 64Cu-Labeled triphenylphosphonium and triphenylarsonium cations as highly tumor-selective imaging agents. J Med Chem. 2007 Oct 18;50(21):5057-69. doi: 10.1021/jm0704088. Epub 2007 Sep 15. PubMed PMID: 17867662.
Cai W, Chen K, Li ZB, Gambhir SS, Chen X. Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature. J Nucl Med. 2007 Nov;48(11):1862-70. doi: 10.2967/jnumed.107.043216. Epub 2007 Oct 17. PubMed PMID: 17942800.
Cao Q, Cai W, Li ZB, Chen K, He L, Li HC, Hui M, Chen X. PET imaging of acute and chronic inflammation in living mice. Eur J Nucl Med Mol Imaging. 2007 Nov;34(11):1832-42. doi: 10.1007/s00259-007-0451-0. Epub 2007 May 31. PubMed PMID: 17541586.
Wu Z, Li ZB, Cai W, He L, Chin FT, Li F, Chen X. 18F-labeled mini-PEG spacered RGD dimer (18F-FPRGD2): synthesis and microPET imaging of alphavbeta3 integrin expression. Eur J Nucl Med Mol Imaging. 2007 Nov;34(11):1823-1831. doi: 10.1007/s00259-007-0427-0. Epub 2007 May 5. PubMed PMID: 17492285; PubMed Central PMCID: PMC4167588.
Li ZB, Wu Z, Chen K, Chin FT, Chen X. Click chemistry for (18)F-labeling of RGD peptides and microPET imaging of tumor integrin alphavbeta3 expression. Bioconjug Chem. 2007 Nov-Dec;18(6):1987-94. doi: 10.1021/bc700226v. Epub 2007 Nov 21. PubMed PMID: 18030991; PubMed Central PMCID: PMC4183694.
Li ZB, Wu Z, Chen K, Ryu EK, Chen X. 18F-labeled BBN-RGD heterodimer for prostate cancer imaging. J Nucl Med. 2008 Mar;49(3):453-61. doi: 10.2967/jnumed.107.048009. Epub 2008 Feb 20. PubMed PMID: 18287274.
Li ZB, Wu Z, Cao Q, Dick DW, Tseng JR, Gambhir SS, Chen X. The synthesis of 18F-FDS and its potential application in molecular imaging. Mol Imaging Biol. 2008 Mar-Apr;10(2):92-98. doi: 10.1007/s11307-007-0125-0. Epub 2007 Dec 21. PubMed PMID: 18097725; PubMed Central PMCID: PMC4143166.
Rodriguez-Porcel M, Cai W, Gheysens O, Willmann JK, Chen K, Wang H, Chen IY, He L, Wu JC, Li ZB, Mohamedali KA, Kim S, Rosenblum MG, Chen X, Gambhir SS. Imaging of VEGF receptor in a rat myocardial infarction model using PET. J Nucl Med. 2008 Apr;49(4):667-73. doi: 10.2967/jnumed.107.040576. PubMed PMID: 18375924; PubMed Central PMCID: PMC2853914.
Alam MR, Dixit V, Kang H, Li ZB, Chen X, Trejo J, Fisher M, Juliano RL. Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis. Nucleic Acids Res. 2008 May;36(8):2764-76. doi: 10.1093/nar/gkn115. Epub 2008 Mar 26. PubMed PMID: 18367474; PubMed Central PMCID: PMC2377441.
Wang H, Chen K, Cai W, Li Z, He L, Kashefi A, Chen X. Integrin-targeted imaging and therapy with RGD4C-TNF fusion protein. Mol Cancer Ther. 2008 May;7(5):1044-53. doi: 10.1158/1535-7163.MCT-07-2084. PubMed PMID: 18483294.
Kim YS, Yang CT, Wang J, Wang L, Li ZB, Chen X, Liu S. Effects of targeting moiety, linker, bifunctional chelator, and molecular charge on biological properties of 64Cu-labeled triphenylphosphonium cations. J Med Chem. 2008 May 22;51(10):2971-84. doi: 10.1021/jm7015045. Epub 2008 Apr 18. PubMed PMID: 18419113.
Li ZB, Chen K, Chen X. (68)Ga-labeled multimeric RGD peptides for microPET imaging of integrin alpha(v)beta (3) expression. Eur J Nucl Med Mol Imaging. 2008 Jun;35(6):1100-8. doi: 10.1007/s00259-007-0692-y. Epub 2008 Jan 19. PubMed PMID: 18204838.
Li ZB, Niu G, Wang H, He L, Yang L, Ploug M, Chen X. Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET. Clin Cancer Res. 2008 Aug 1;14(15):4758-66. doi: 10.1158/1078-0432.CCR-07-4434. PubMed PMID: 18676745.
Cao Q, Li ZB, Chen K, Wu Z, He L, Neamati N, Chen X. Evaluation of biodistribution and anti-tumor effect of a dimeric RGD peptide-paclitaxel conjugate in mice with breast cancer. Eur J Nucl Med Mol Imaging. 2008 Aug;35(8):1489-98. doi: 10.1007/s00259-008-0744-y. Epub 2008 Mar 29. PubMed PMID: 18373091.
Lee HY, Li Z, Chen K, Hsu AR, Xu C, Xie J, Sun S, Chen X. PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles. J Nucl Med. 2008 Aug;49(8):1371-9. doi: 10.2967/jnumed.108.051243. Epub 2008 Jul 16. PubMed PMID: 18632815.
Yang CT, Kim YS, Wang J, Wang L, Shi J, Li ZB, Chen X, Fan M, Li JJ, Liu S. 64Cu-labeled 2-(diphenylphosphoryl)ethyldiphenylphosphonium cations as highly selective tumor imaging agents: effects of linkers and chelates on radiotracer biodistribution characteristics. Bioconjug Chem. 2008 Oct;19(10):2008-22. doi: 10.1021/bc8002056. Epub 2008 Sep 3. PubMed PMID: 18763821; PubMed Central PMCID: PMC2637998.
Chen K, Li ZB, Wang H, Cai W, Chen X. Dual-modality optical and positron emission tomography imaging of vascular endothelial growth factor receptor on tumor vasculature using quantum dots. Eur J Nucl Med Mol Imaging. 2008 Dec;35(12):2235-44. doi: 10.1007/s00259-008-0860-8. Epub 2008 Jun 20. PubMed PMID: 18566815.
Cai W, Guzman R, Hsu AR, Wang H, Chen K, Sun G, Gera A, Choi R, Bliss T, He L, Li ZB, Maag AL, Hori N, Zhao H, Moseley M, Steinberg GK, Chen X. Positron emission tomography imaging of poststroke angiogenesis. Stroke. 2009 Jan;40(1):270-7. doi: 10.1161/STROKEAHA.108.517474. Epub 2008 Oct 23. PubMed PMID: 18948613.
Chen K, Cai W, Li ZB, Wang H, Chen X. Quantitative PET imaging of VEGF receptor expression. Mol Imaging Biol. 2009 Jan-Feb;11(1):15-22. doi: 10.1007/s11307-008-0172-1. Epub 2008 Sep 11. PubMed PMID: 18784964.
Li ZB, Chen X. MicroPET, MicroSPECT, and NIR fluorescence imaging of biomolecules in vivo. Methods Mol Biol. 2009;544:461-81. doi: 10.1007/978-1-59745-483-4_31. PubMed PMID: 19488719.
Cao F, Li Z, Lee A, Liu Z, Chen K, Wang H, Cai W, Chen X, Wu JC. Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation. Cancer Res. 2009 Apr 1;69(7):2709-13. doi: 10.1158/0008-5472.CAN-08-4122. Epub 2009 Mar 24. PubMed PMID: 19318556; PubMed Central PMCID: PMC2866177.
Niu G, Li Z, Xie J, Le QT, Chen X. PET of EGFR antibody distribution in head and neck squamous cell carcinoma models. J Nucl Med. 2009 Jul;50(7):1116-23. doi: 10.2967/jnumed.109.061820. Epub 2009 Jun 12. PubMed PMID: 19525473; PubMed Central PMCID: PMC6435376.
Liu Z, Li ZB, Cao Q, Liu S, Wang F, Chen X. Small-animal PET of tumors with (64)Cu-labeled RGD-bombesin heterodimer. J Nucl Med. 2009 Jul;50(7):1168-77. doi: 10.2967/jnumed.108.061739. Epub 2009 Jun 12. PubMed PMID: 19525469.
Niu G, Li Z, Cao Q, Chen X. Monitoring therapeutic response of human ovarian cancer to 17-DMAG by noninvasive PET imaging with (64)Cu-DOTA-trastuzumab. Eur J Nucl Med Mol Imaging. 2009 Sep;36(9):1510-9. doi: 10.1007/s00259-009-1158-1. Epub 2009 May 14. PubMed PMID: 19440708; PubMed Central PMCID: PMC3596115.
Li ZB, Chen K, Wu Z, Wang H, Niu G, Chen X. 64Cu-labeled PEGylated polyethylenimine for cell trafficking and tumor imaging. Mol Imaging Biol. 2009 Nov-Dec;11(6):415-23. doi: 10.1007/s11307-009-0228-x. Epub 2009 May 9. PubMed PMID: 19430846.
Cai H, Li Z, Huang CW, Park R, Shahinian AH, Conti PS. An improved synthesis and biological evaluation of a new cage-like bifunctional chelator, 4-((8-amino-3,6,10,13,16,19-hexaazabicyclo[6.6.6]icosane-1-ylamino)methyl)benzoic acid, for 64Cu radiopharmaceuticals. Nucl Med Biol. 2010 Jan;37(1):57-65. doi: 10.1016/j.nucmedbio.2009.09.001. Epub 2009 Oct 12. PubMed PMID: 20122669.
Cai H, Li Z, Huang CW, Shahinian AH, Wang H, Park R, Conti PS. Evaluation of copper-64 labeled AmBaSar conjugated cyclic RGD peptide for improved microPET imaging of integrin alphavbeta3 expression. Bioconjug Chem. 2010 Aug 18;21(8):1417-24. doi: 10.1021/bc900537f. PubMed PMID: 20666401.
Li Z, Conti PS. Radiopharmaceutical chemistry for positron emission tomography. Adv Drug Deliv Rev. 2010 Aug 30;62(11):1031-51. doi: 10.1016/j.addr.2010.09.007. Epub 2010 Sep 18. Review. PubMed PMID: 20854860.
MacKay JA, Li Z. Theranostic agents that co-deliver therapeutic and imaging agents?. Adv Drug Deliv Rev. 2010 Aug 30;62(11):1003-4. doi: 10.1016/j.addr.2010.10.001. Epub 2010 Oct 16. PubMed PMID: 20937334.
Li Z, Cai H, Hassink M, Blackman ML, Brown RC, Conti PS, Fox JM. Tetrazine-trans-cyclooctene ligation for the rapid construction of 18F labeled probes. Chem Commun (Camb). 2010 Nov 14;46(42):8043-5. doi: 10.1039/c0cc03078c. Epub 2010 Sep 22. PubMed PMID: 20862423; PubMed Central PMCID: PMC3230320.
Cai H, Li Z, Huang CW, Park R, Conti PS. (64)Cu labeled AmBaSar-RGD2 for micro-PET imaging of integrin αvβ3 expression. Curr Radiopharm. 2011 Jan;4(1):68-74. doi: 10.2174/1874471011104010068. PubMed PMID: 22191616.
Li Z, Cai H, Conti PS. Improved synthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-β-D-arabinofuranosyluracil ([18F]FMAU). Curr Radiopharm. 2011 Jan;4(1):24-30. doi: 10.2174/1874471011104010024. PubMed PMID: 22191612.
Li Z, Cai H, Conti PS. Automated synthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-β-D-arabinofuranosyluracil ([18F]-FMAU) using a one reactor radiosynthesis module. Nucl Med Biol. 2011 Feb;38(2):201-6. doi: 10.1016/j.nucmedbio.2010.08.010. Epub 2010 Dec 3. PubMed PMID: 21315275.
Huang CW, Li Z, Cai H, Shahinian T, Conti PS. Biological stability evaluation of the α2β1 receptor imaging agents: diamsar and DOTA conjugated DGEA peptide. Bioconjug Chem. 2011 Feb 16;22(2):256-63. doi: 10.1021/bc100388g. Epub 2011 Jan 18. PubMed PMID: 21244039.
Cai H, Li Z, Conti PS. The improved syntheses of 5-substituted 2'-[18F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([18F]FAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU and [18F]FIAU) using a multistep one-pot strategy. Nucl Med Biol. 2011 Jul;38(5):659-66. doi: 10.1016/j.nucmedbio.2011.01.003. Epub 2011 Mar 30. PubMed PMID: 21718941.
Huang CW, Li Z, Cai H, Chen K, Shahinian T, Conti PS. Design, synthesis and validation of integrin α2β1-targeted probe for microPET imaging of prostate cancer. Eur J Nucl Med Mol Imaging. 2011 Jul;38(7):1313-22. doi: 10.1007/s00259-011-1752-x. Epub 2011 Feb 25. PubMed PMID: 21350963.
Huang CW, Li Z, Cai H, Shahinian T, Conti PS. Novel α(2)β(1) integrin-targeted peptide probes for prostate cancer imaging. Mol Imaging. 2011 Aug;10(4):284-94. doi: 10.2310/7290.2010.00044. Epub 2011 Apr 1. PubMed PMID: 21486537.
Wu Z, Todorov I, Li L, Bading JR, Li Z, Nair I, Ishiyama K, Colcher D, Conti PE, Fraser SE, Shively JE, Kandeel F. In vivo imaging of transplanted islets with 64Cu-DO3A-VS-Cys40-Exendin-4 by targeting GLP-1 receptor. Bioconjug Chem. 2011 Aug 17;22(8):1587-94. doi: 10.1021/bc200132t. Epub 2011 Jul 14. PubMed PMID: 21692471.
Selvaraj R, Liu S, Hassink M, Huang CW, Yap LP, Park R, Fox JM, Li Z, Conti PS. Tetrazine-trans-cyclooctene ligation for the rapid construction of integrin αvβ₃ targeted PET tracer based on a cyclic RGD peptide. Bioorg Med Chem Lett. 2011 Sep 1;21(17):5011-4. doi: 10.1016/j.bmcl.2011.04.116. Epub 2011 May 4. PubMed PMID: 21601452; PubMed Central PMCID: PMC3230322.
Liu S, Li Z, Yap LP, Huang CW, Park R, Conti PS. Efficient preparation and biological evaluation of a novel multivalency bifunctional chelator for 64Cu radiopharmaceuticals. Chemistry. 2011 Sep 5;17(37):10222-5. doi: 10.1002/chem.201101894. Epub 2011 Aug 4. PubMed PMID: 21815227; PubMed Central PMCID: PMC5367772.
Li Z, Lin TP, Liu S, Huang CW, Hudnall TW, Gabbaï FP, Conti PS. Rapid aqueous [18F]-labeling of a bodipy dye for positron emission tomography/fluorescence dual modality imaging. Chem Commun (Camb). 2011 Sep 7;47(33):9324-6. doi: 10.1039/c1cc13089g. Epub 2011 Jul 21. PubMed PMID: 21779546.
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