My Bibliography

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Utkina I, Fan Y, Willing BP, Parkinson J. Correction: Metabolic modeling of microbial communities in the chicken ceca reveals a landscape of competition and co-operation. Microbiome. 2025 Dec 22;13(1):256. doi: 10.1186/s40168-025-02323-3. PubMed PMID: 41430632; PubMed Central PMCID: PMC12720474.

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Utkina I, Fan Y, Willing BP, Parkinson J. Metabolic modeling of microbial communities in the chicken ceca reveals a landscape of competition and co-operation. Microbiome. 2025 Nov 27;13(1):248. doi: 10.1186/s40168-025-02241-4. PubMed PMID: 41310806; PubMed Central PMCID: PMC12661832.

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Campisi SC, Zhang F, Seo M, Muha J, Schumacher A, De Luca I, Bradley-Ridout G, Merriman K, Parkinson J, Korczak DJ. The gut microbiome and child and adolescent depression and anxiety: a systematic review and meta-analysis with youth consultation. Gut Microbiome (Camb). 2025;6:e17. doi: 10.1017/gmb.2025.10013. eCollection 2025. Review. PubMed PMID: 41079946; PubMed Central PMCID: PMC12509154.

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Alves-Ferreira EVC, Galac MR, Lorenzi HA, Ho MCW, Tjhin ET, Popovic A, Parkinson J, Grigg ME. Whole Genome Sequence of the gut commensal protist Tritrichomonas musculus isolated from laboratory mice. Sci Data. 2025 Apr 8;12(1):590. doi: 10.1038/s41597-025-04921-0. PubMed PMID: 40199934; PubMed Central PMCID: PMC11978803.

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Winsor NJ, Bayer G, Singh O, Chan JK, Li LY, Lieng BY, Foerster E, Popovic A, Tsankov BK, Maughan H, Lemire P, Tam E, Streutker C, Chen L, Heaver SL, Ley RE, Parkinson J, Montenegro-Burke JR, Birchenough GMH, Philpott DJ, Girardin SE. Cross-kingdom-mediated detection of intestinal protozoa through NLRP6. Cell Host Microbe. 2025 Mar 12;33(3):388-407.e9. doi: 10.1016/j.chom.2025.02.008. Epub 2025 Mar 4. PubMed PMID: 40043701.

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Peng H, Kotelnikov S, Egbert ME, Ofaim S, Stevens GC, Phanse S, Saccon T, Ignatov M, Dutta S, Istace Z, Moutaoufik MT, Aoki H, Kewalramani N, Sun J, Gong Y, Padhorny D, Poda G, Alekseenko A, Porter KA, Jones G, Rodionova I, Guo H, Pogoutse O, Datta S, Saier M, Crovella M, Vajda S, Moreno-Hagelsieb G, Parkinson J, Segre D, Babu M, Kozakov D, Emili A. Ligand interaction landscape of transcription factors and essential enzymes in E. coli. Cell. 2025 Mar 6;188(5):1441-1455.e15. doi: 10.1016/j.cell.2025.01.003. Epub 2025 Jan 24. PubMed PMID: 39862855.

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Cao EY, Burrows K, Chiaranunt P, Popovic A, Zhou X, Xie C, Thakur A, Britton G, Spindler M, Ngai L, Tai SL, Dasoveanu DC, Nguyen A, Faith JJ, Parkinson J, Gommerman JL, Mortha A. The protozoan commensal Tritrichomonas musculis is a natural adjuvant for mucosal IgA. J Exp Med. 2024 Dec 2;221(12). doi: 10.1084/jem.20221727. Epub 2024 Nov 13. PubMed PMID: 39535524; PubMed Central PMCID: PMC11561467.

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Wasan Y, Baxter JB, Spiegel-Feld C, Begum K, Rizvi A, Iqbal J, Hulst J, Bandsma R, Suleman S, Soofi S, Parkinson J, Bhutta ZA. Elucidating the dynamics and impact of the gut microbiome on maternal nutritional status during pregnancy, effect on pregnancy outcomes and infant health in rural Pakistan: study protocol for a prospective, longitudinal observational study. BMJ Open. 2024 Aug 12;14(8):e081629. doi: 10.1136/bmjopen-2023-081629. PubMed PMID: 39134435; PubMed Central PMCID: PMC11331926.

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Swapna LS, Stevens GC, Sardinha-Silva A, Hu LZ, Brand V, Fusca DD, Wan C, Xiong X, Boyle JP, Grigg ME, Emili A, Parkinson J. ToxoNet: A high confidence map of protein-protein interactions in Toxoplasma gondii. PLoS Comput Biol. 2024 Jun;20(6):e1012208. doi: 10.1371/journal.pcbi.1012208. eCollection 2024 Jun. PubMed PMID: 38900844; PubMed Central PMCID: PMC11219001.

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Kairmi SH, Abdelaziz K, Spahany H, Astill J, Trott D, Wang B, Wang A, Parkinson J, Sharif S. Intestinal microbiome profiles in broiler chickens raised without antibiotics exhibit altered microbiome dynamics relative to conventionally raised chickens. PLoS One. 2024;19(4):e0301110. doi: 10.1371/journal.pone.0301110. eCollection 2024. PubMed PMID: 38568936; PubMed Central PMCID: PMC10990180.

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Chan D, Cromar GL, Taj B, Parkinson J. Cell4D: a general purpose spatial stochastic simulator for cellular pathways. BMC Bioinformatics. 2024 Mar 21;25(1):121. doi: 10.1186/s12859-024-05739-0. PubMed PMID: 38515063; PubMed Central PMCID: PMC10956314.

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Verma B, Parkinson J. HiTaxon: a hierarchical ensemble framework for taxonomic classification of short reads. Bioinform Adv. 2024;4(1):vbae016. doi: 10.1093/bioadv/vbae016. eCollection 2024. PubMed PMID: 38371920; PubMed Central PMCID: PMC10873905.

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Popovic A, Cao EY, Han J, Nursimulu N, Alves-Ferreira EVC, Burrows K, Kennard A, Alsmadi N, Grigg ME, Mortha A, Parkinson J. Commensal protist Tritrichomonas musculus exhibits a dynamic life cycle that induces extensive remodeling of the gut microbiota. ISME J. 2024 Jan 8;18(1). doi: 10.1093/ismejo/wrae023. PubMed PMID: 38366179; PubMed Central PMCID: PMC10944700.

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Chieu RV, Hamilton K, Ryan PM, Copeland J, Wang PW, Retnakaran R, Guttman DS, Parkinson J, Hamilton JK. The impact of gestational diabetes on functional capacity of the infant gut microbiome is modest and transient. Gut Microbes. 2024 Jan-Dec;16(1):2356277. doi: 10.1080/19490976.2024.2356277. Epub 2024 May 26. PubMed PMID: 38798005; PubMed Central PMCID: PMC11135868.

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Romano K, Shah AN, Schumacher A, Zasowski C, Zhang T, Bradley-Ridout G, Merriman K, Parkinson J, Szatmari P, Campisi SC, Korczak DJ. The gut microbiome in children with mood, anxiety, and neurodevelopmental disorders: An umbrella review. Gut Microbiome (Camb). 2023;4:e18. doi: 10.1017/gmb.2023.16. eCollection 2023. Review. PubMed PMID: 39295902; PubMed Central PMCID: PMC11406386.

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Taj B, Adeolu M, Xiong X, Ang J, Nursimulu N, Parkinson J. MetaPro: a scalable and reproducible data processing and analysis pipeline for metatranscriptomic investigation of microbial communities. Microbiome. 2023 Jun 27;11(1):143. doi: 10.1186/s40168-023-01562-6. PubMed PMID: 37370188; PubMed Central PMCID: PMC10294448.

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Nursimulu N, Moses AM, Parkinson J. Architect: A tool for aiding the reconstruction of high-quality metabolic models through improved enzyme annotation. PLoS Comput Biol. 2022 Sep;18(9):e1010452. doi: 10.1371/journal.pcbi.1010452. eCollection 2022 Sep. PubMed PMID: 36074804; PubMed Central PMCID: PMC9488769.

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Zou A, Nadeau K, Xiong X, Wang PW, Copeland JK, Lee JY, Pierre JS, Ty M, Taj B, Brumell JH, Guttman DS, Sharif S, Korver D, Parkinson J. Systematic profiling of the chicken gut microbiome reveals dietary supplementation with antibiotics alters expression of multiple microbial pathways with minimal impact on community structure. Microbiome. 2022 Aug 15;10(1):127. doi: 10.1186/s40168-022-01319-7. PubMed PMID: 35965349; PubMed Central PMCID: PMC9377095.

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Cromar GL, Epp JR, Popovic A, Gu Y, Ha V, Walters BJ, St Pierre J, Xiong X, Howland JG, Josselyn SA, Frankland PW, Parkinson J. Toxoplasma infection in male mice alters dopamine-sensitive behaviors and host gene expression patterns associated with neuropsychiatric disease. PLoS Negl Trop Dis. 2022 Jul;16(7):e0010600. doi: 10.1371/journal.pntd.0010600. eCollection 2022 Jul. PubMed PMID: 35857765; PubMed Central PMCID: PMC9342775.

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Kairmi SH, Taha-Abdelaziz K, Yitbarek A, Sargolzaei M, Spahany H, Astill J, Shojadoost B, Alizadeh M, Kulkarni RR, Parkinson J, Sharif S. Effects of therapeutic levels of dietary antibiotics on the cecal microbiome composition of broiler chickens. Poult Sci. 2022 Jun;101(6):101864. doi: 10.1016/j.psj.2022.101864. Epub 2022 Mar 17. PubMed PMID: 35477134; PubMed Central PMCID: PMC9061639.

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Ty M, Taha-Abdelaziz K, Demey V, Castex M, Sharif S, Parkinson J. Performance of distinct microbial based solutions in a Campylobacter infection challenge model in poultry. Anim Microbiome. 2022 Jan 3;4(1):2. doi: 10.1186/s42523-021-00157-6. PubMed PMID: 34980288; PubMed Central PMCID: PMC8722297.

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Popovic A, Bourdon C, Wang PW, Guttman DS, Soofi S, Bhutta ZA, Bandsma RHJ, Parkinson J, Pell LG. Micronutrient supplements can promote disruptive protozoan and fungal communities in the developing infant gut. Nat Commun. 2021 Nov 18;12(1):6729. doi: 10.1038/s41467-021-27010-3. PubMed PMID: 34795270; PubMed Central PMCID: PMC8602372.

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Jiang JX, Wellhauser L, Laselva O, Utkina I, Bozoky Z, Gunawardena T, Ngan Z, Xia S, Di Paola M, Eckford PDW, Ratjen F, Moraes TJ, Parkinson J, Wong AP, Bear CE. A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients. Stem Cell Reports. 2021 Nov 9;16(11):2825-2837. doi: 10.1016/j.stemcr.2021.09.020. Epub 2021 Oct 21. PubMed PMID: 34678210; PubMed Central PMCID: PMC8581165.

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Dacquay LC, Tsang D, Chan D, Parkinson J, Philpott DJ, McMillen DR. E.coli Nissle increases transcription of flagella assembly and formate hydrogenlyase genes in response to colitis. Gut Microbes. 2021 Jan-Dec;13(1):1994832. doi: 10.1080/19490976.2021.1994832. PubMed PMID: 34751631; PubMed Central PMCID: PMC8583297.

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Curran DM, Grote A, Nursimulu N, Geber A, Voronin D, Jones DR, Ghedin E, Parkinson J. Modeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets. Elife. 2020 Aug 11;9. doi: 10.7554/eLife.51850. PubMed PMID: 32779567; PubMed Central PMCID: PMC7419141.

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Pourhaghighi R, Ash PEA, Phanse S, Goebels F, Hu LZM, Chen S, Zhang Y, Wierbowski SD, Boudeau S, Moutaoufik MT, Malty RH, Malolepsza E, Tsafou K, Nathan A, Cromar G, Guo H, Abdullatif AA, Apicco DJ, Becker LA, Gitler AD, Pulst SM, Youssef A, Hekman R, Havugimana PC, White CA, Blum BC, Ratti A, Bryant CD, Parkinson J, Lage K, Babu M, Yu H, Bader GD, Wolozin B, Emili A. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst. 2020 Apr 22;10(4):333-350.e14. doi: 10.1016/j.cels.2020.03.003. PubMed PMID: 32325033; PubMed Central PMCID: PMC7938770.

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Bundalovic-Torma C, Whitfield GB, Marmont LS, Howell PL, Parkinson J. A systematic pipeline for classifying bacterial operons reveals the evolutionary landscape of biofilm machineries. PLoS Comput Biol. 2020 Apr;16(4):e1007721. doi: 10.1371/journal.pcbi.1007721. eCollection 2020 Apr. PubMed PMID: 32236097; PubMed Central PMCID: PMC7112194.

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Whitfield GB, Marmont LS, Bundalovic-Torma C, Razvi E, Roach EJ, Khursigara CM, Parkinson J, Howell PL. Discovery and characterization of a Gram-positive Pel polysaccharide biosynthetic gene cluster. PLoS Pathog. 2020 Apr;16(4):e1008281. doi: 10.1371/journal.ppat.1008281. eCollection 2020 Apr. PubMed PMID: 32236137; PubMed Central PMCID: PMC7112168.

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Zou A, Nadeau K, Wang PW, Lee JY, Guttman DS, Sharif S, Korver DR, Brumell JH, Parkinson J. Accumulation of genetic variants associated with immunity in the selective breeding of broilers. BMC Genet. 2020 Jan 17;21(1):5. doi: 10.1186/s12863-020-0807-z. PubMed PMID: 31952471; PubMed Central PMCID: PMC6969402.

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Yitbarek A, Astill J, Hodgins DC, Parkinson J, Nagy É, Sharif S. Commensal gut microbiota can modulate adaptive immune responses in chickens vaccinated with whole inactivated avian influenza virus subtype H9N2. Vaccine. 2019 Oct 16;37(44):6640-6647. doi: 10.1016/j.vaccine.2019.09.046. Epub 2019 Sep 18. PubMed PMID: 31542262.

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Zhang J, Parkinson J. PopNetD3-A Network-Based Web Resource for Exploring Population Structure. Genome Biol Evol. 2019 Jul 1;11(7):1730-1735. doi: 10.1093/gbe/evz100. PubMed PMID: 31095319; PubMed Central PMCID: PMC6668580.

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Adeolu M, Parkinson J, Xiong X. Analyzing Metabolic Pathways in Microbiomes. Methods Mol Biol. 2018;1849:291-307. doi: 10.1007/978-1-4939-8728-3_18. PubMed PMID: 30298261.

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Popovic A, Parkinson J. Characterization of Eukaryotic Microbiome Using 18S Amplicon Sequencing. Methods Mol Biol. 2018;1849:29-48. doi: 10.1007/978-1-4939-8728-3_3. PubMed PMID: 30298246.

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Popovic A, Bourdon C, Wang PW, Guttman DS, Voskuijl W, Grigg ME, Bandsma RHJ, Parkinson J. Design and application of a novel two-amplicon approach for defining eukaryotic microbiota. Microbiome. 2018 Dec 20;6(1):228. doi: 10.1186/s40168-018-0612-3. PubMed PMID: 30572961; PubMed Central PMCID: PMC6302507.

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Zou A, Sharif S, Parkinson J. Lactobacillus elicits a 'Marmite effect' on the chicken cecal microbiome. NPJ Biofilms Microbiomes. 2018;4:27. doi: 10.1038/s41522-018-0070-5. eCollection 2018. PubMed PMID: 30455975; PubMed Central PMCID: PMC6226495.

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International Helminth Genomes Consortium. Comparative genomics of the major parasitic worms. Nat Genet. 2019 Jan;51(1):163-174. doi: 10.1038/s41588-018-0262-1. Epub 2018 Nov 5. PubMed PMID: 30397333; PubMed Central PMCID: PMC6349046.

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Nursimulu N, Xu LL, Wasmuth JD, Krukov I, Parkinson J. Improved enzyme annotation with EC-specific cutoffs using DETECT v2. Bioinformatics. 2018 Oct 1;34(19):3393-3395. doi: 10.1093/bioinformatics/bty368. PubMed PMID: 29722785; PubMed Central PMCID: PMC6157075.

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Yitbarek A, Taha-Abdelaziz K, Hodgins DC, Read L, Nagy É, Weese JS, Caswell JL, Parkinson J, Sharif S. Gut microbiota-mediated protection against influenza virus subtype H9N2 in chickens is associated with modulation of the innate responses. Sci Rep. 2018 Sep 4;8(1):13189. doi: 10.1038/s41598-018-31613-0. PubMed PMID: 30181578; PubMed Central PMCID: PMC6123399.

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Swapna LS, Molinaro AM, Lindsay-Mosher N, Pearson BJ, Parkinson J. Comparative transcriptomic analyses and single-cell RNA sequencing of the freshwater planarian Schmidtea mediterranea identify major cell types and pathway conservation. Genome Biol. 2018 Aug 24;19(1):124. doi: 10.1186/s13059-018-1498-x. PubMed PMID: 30143032; PubMed Central PMCID: PMC6109357.

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Yitbarek A, Alkie T, Taha-Abdelaziz K, Astill J, Rodriguez-Lecompte JC, Parkinson J, Nagy É, Sharif S. Gut microbiota modulates type I interferon and antibody-mediated immune responses in chickens infected with influenza virus subtype H9N2. Benef Microbes. 2018 Apr 25;9(3):417-427. doi: 10.3920/BM2017.0088. Epub 2018 Jan 30. PubMed PMID: 29380643.

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Yitbarek A, Weese JS, Alkie TN, Parkinson J, Sharif S. Influenza A virus subtype H9N2 infection disrupts the composition of intestinal microbiota of chickens. FEMS Microbiol Ecol. 2018 Jan 1;94(1). doi: 10.1093/femsec/fix165. PubMed PMID: 29228270.

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Babu M, Bundalovic-Torma C, Calmettes C, Phanse S, Zhang Q, Jiang Y, Minic Z, Kim S, Mehla J, Gagarinova A, Rodionova I, Kumar A, Guo H, Kagan O, Pogoutse O, Aoki H, Deineko V, Caufield JH, Holtzapple E, Zhang Z, Vastermark A, Pandya Y, Lai CC, El Bakkouri M, Hooda Y, Shah M, Burnside D, Hooshyar M, Vlasblom J, Rajagopala SV, Golshani A, Wuchty S, F Greenblatt J, Saier M, Uetz P, F Moraes T, Parkinson J, Emili A. Global landscape of cell envelope protein complexes in Escherichia coli. Nat Biotechnol. 2018 Jan;36(1):103-112. doi: 10.1038/nbt.4024. Epub 2017 Nov 27. PubMed PMID: 29176613; PubMed Central PMCID: PMC5922438.

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Malty RH, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, Minic Z, Goebels F, Musso G, Wu Z, Abou-Tok H, Meyer M, Deineko V, Kassir S, Sidhu V, Jessulat M, Scott NE, Xiong X, Vlasblom J, Prasad B, Foster LJ, Alberio T, Garavaglia B, Yu H, Bader GD, Nakamura K, Parkinson J, Babu M. A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling. Cell Syst. 2017 Dec 27;5(6):564-577.e12. doi: 10.1016/j.cels.2017.10.010. Epub 2017 Nov 8. PubMed PMID: 29128334; PubMed Central PMCID: PMC5746455.

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Xiong X, Bales ES, Ir D, Robertson CE, McManaman JL, Frank DN, Parkinson J. Perilipin-2 modulates dietary fat-induced microbial global gene expression profiles in the mouse intestine. Microbiome. 2017 Sep 6;5(1):117. doi: 10.1186/s40168-017-0327-x. PubMed PMID: 28877764; PubMed Central PMCID: PMC5588750.

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Zhang J, Khan A, Kennard A, Grigg ME, Parkinson J. PopNet: A Markov Clustering Approach to Study Population Genetic Structure. Mol Biol Evol. 2017 Jul 1;34(7):1799-1811. doi: 10.1093/molbev/msx110. PubMed PMID: 28383661; PubMed Central PMCID: PMC5850731.

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Vetere G, Kenney JW, Tran LM, Xia F, Steadman PE, Parkinson J, Josselyn SA, Frankland PW. Chemogenetic Interrogation of a Brain-wide Fear Memory Network in Mice. Neuron. 2017 Apr 19;94(2):363-374.e4. doi: 10.1016/j.neuron.2017.03.037. PubMed PMID: 28426969.

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Bertschi NL, Toenhake CG, Zou A, Niederwieser I, Henderson R, Moes S, Jenoe P, Parkinson J, Bartfai R, Voss TS. Malaria parasites possess a telomere repeat-binding protein that shares ancestry with transcription factor IIIA. Nat Microbiol. 2017 Mar 13;2:17033. doi: 10.1038/nmicrobiol.2017.33. PubMed PMID: 28288093.

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Swapna LS, Parkinson J. Genomics of apicomplexan parasites. Crit Rev Biochem Mol Biol. 2017 Jun;52(3):254-273. doi: 10.1080/10409238.2017.1290043. Epub 2017 Feb 22. Review. PubMed PMID: 28276701; PubMed Central PMCID: PMC6813780.

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Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, Ribeiro JM, Rogers MB, Stanley E, Swapna LS, Tsai IJ, Unnasch TR, Voronin D, Parkinson J, Nutman TB, Ghedin E, Berriman M, Lustigman S. The genome of Onchocerca volvulus, agent of river blindness. Nat Microbiol. 2016 Nov 21;2:16216. doi: 10.1038/nmicrobiol.2016.216. PubMed PMID: 27869790; PubMed Central PMCID: PMC5310847.

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Di Giovanni V, Bourdon C, Wang DX, Seshadri S, Senga E, Versloot CJ, Voskuijl W, Semba RD, Trehan I, Moaddel R, Ordiz MI, Zhang L, Parkinson J, Manary MJ, Bandsma RH. Metabolomic Changes in Serum of Children with Different Clinical Diagnoses of Malnutrition. J Nutr. 2016 Dec;146(12):2436-2444. doi: 10.3945/jn.116.239145. Epub 2016 Nov 2. PubMed PMID: 27807038; PubMed Central PMCID: PMC5118769.