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van der Wal L, Bezstarosti K, Demmers JAA. A ubiquitinome analysis to study the functional roles of the proteasome associated deubiquitinating enzymes USP14 and UCH37. J Proteomics. 2022 Jun 30;262:104592. doi: 10.1016/j.jprot.2022.104592. Epub 2022 Apr 27. PubMed PMID: 35489684.
Demmers JAA. Editorial. J Proteomics. 2022 Jun 30;262:104593. doi: 10.1016/j.jprot.2022.104593. Epub 2022 Apr 20. PubMed PMID: 35483230.
Berdowski WM, van der Linde HC, Breur M, Oosterhof N, Beerepoot S, Sanderson L, Wijnands LI, de Jong P, Tsai-Meu-Chong E, de Valk W, de Witte M, van IJcken WFJ, Demmers J, van der Knaap MS, Bugiani M, Wolf NI, van Ham TJ. Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy. Acta Neuropathol. 2022 Jun 17;. doi: 10.1007/s00401-022-02440-5. [Epub ahead of print] PubMed PMID: 35713703.
Ne E, Crespo R, Izquierdo-Lara R, Rao S, Koçer S, Górska A, van Staveren T, Kan TW, van de Vijver D, Dekkers D, Rokx C, Moulos P, Hatzis P, Palstra RJ, Demmers J, Mahmoudi T. Catchet-MS identifies IKZF1-targeting thalidomide analogues as novel HIV-1 latency reversal agents. Nucleic Acids Res. 2022 Jun 10;50(10):5577-5598. doi: 10.1093/nar/gkac407. PubMed PMID: 35640596.
Schilders KAA, Edel GG, Eenjes E, Oresta B, Birkhoff J, Boerema-de Munck A, Buscop-van Kempen M, Liakopoulos P, Kolovos P, Demmers JAA, Poot R, Wijnen RMH, Tibboel D, Rottier RJ. Identification of SOX2 Interacting Proteins in the Developing Mouse Lung With Potential Implications for Congenital Diaphragmatic Hernia. Front Pediatr. 2022;10:881287. doi: 10.3389/fped.2022.881287. eCollection 2022. PubMed PMID: 35615634; PubMed Central PMCID: PMC9124971.
van Toorn M, Turkyilmaz Y, Han S, Zhou D, Kim HS, Salas-Armenteros I, Kim M, Akita M, Wienholz F, Raams A, Ryu E, Kang S, Theil AF, Bezstarosti K, Tresini M, Giglia-Mari G, Demmers JA, Schärer OD, Choi JH, Vermeulen W, Marteijn JA. Active DNA damage eviction by HLTF stimulates nucleotide excision repair. Mol Cell. 2022 Apr 7;82(7):1343-1358.e8. doi: 10.1016/j.molcel.2022.02.020. Epub 2022 Mar 9. PubMed PMID: 35271816.
Konietzny A, Grendel J, Kadek A, Bucher M, Han Y, Hertrich N, Dekkers DHW, Demmers JAA, Grünewald K, Uetrecht C, Mikhaylova M. Caldendrin and myosin V regulate synaptic spine apparatus localization via ER stabilization in dendritic spines. EMBO J. 2022 Feb 15;41(4):e106523. doi: 10.15252/embj.2020106523. Epub 2021 Dec 22. PubMed PMID: 34935159; PubMed Central PMCID: PMC8844991.
Piët ACA, Post M, Dekkers D, Demmers JAA, Fornerod M. Proximity Ligation Mapping of Microcephaly Associated SMPD4 Shows Association with Components of the Nuclear Pore Membrane. Cells. 2022 Feb 15;11(4). doi: 10.3390/cells11040674. PubMed PMID: 35203325; PubMed Central PMCID: PMC8870324.
Jadaun PK, Zhang S, Koedam M, Demmers J, Chatterjee S, van Leeuwen JP, van der Eerden BC. Inhibition of hypoxia-induced Mucin 1 alters the proteomic composition of human osteoblast-produced extracellular matrix, leading to reduced osteogenic and angiogenic potential. J Cell Physiol. 2022 Feb;237(2):1440-1454. doi: 10.1002/jcp.30617. Epub 2021 Oct 22. PubMed PMID: 34687046.
Keulers TG, Libregts SF, Beaumont JEJ, Savelkouls KG, Bussink J, Duimel H, Dubois L, Zonneveld MI, López-Iglesias C, Bezstarosti K, Demmers JA, Vooijs M, Wauben M, Rouschop KMA. Secretion of pro-angiogenic extracellular vesicles during hypoxia is dependent on the autophagy-related protein GABARAPL1. J Extracell Vesicles. 2021 Dec;10(14):e12166. doi: 10.1002/jev2.12166. PubMed PMID: 34859607; PubMed Central PMCID: PMC8640512.
Tejeda-Mora H, Leon LG, Demmers J, Baan CC, Reinders MEJ, Bleck B, Lombardo E, Merino A, Hoogduijn MJ. Proteomic Analysis of Mesenchymal Stromal Cell-Derived Extracellular Vesicles and Reconstructed Membrane Particles. Int J Mol Sci. 2021 Nov 29;22(23). doi: 10.3390/ijms222312935. PubMed PMID: 34884740; PubMed Central PMCID: PMC8657583.
Thijssen KL, van der Woude M, Davó-Martínez C, Dekkers DHW, Sabatella M, Demmers JAA, Vermeulen W, Lans H. C. elegans TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repair. Commun Biol. 2021 Nov 25;4(1):1336. doi: 10.1038/s42003-021-02875-8. PubMed PMID: 34824371; PubMed Central PMCID: PMC8617094.
Schellenbauer A, Guilly MN, Grall R, Le Bars R, Paget V, Kortulewski T, Sutcu H, Mathé C, Hullo M, Biard D, Leteurtre F, Barroca V, Corre Y, Irbah L, Rass E, Theze B, Bertrand P, Demmers JAA, Guirouilh-Barbat J, Lopez BS, Chevillard S, Delic J. Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ. Nucleic Acids Res. 2021 Nov 18;49(20):11728-11745. doi: 10.1093/nar/gkab980. PubMed PMID: 34718776; PubMed Central PMCID: PMC8599715.
Bezstarosti K, Lamers MM, Doff WAS, Wever PC, Thai KTD, van Kampen JJA, Haagmans BL, Demmers JAA. Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens. PLoS One. 2021;16(11):e0259165. doi: 10.1371/journal.pone.0259165. eCollection 2021. PubMed PMID: 34762662; PubMed Central PMCID: PMC8584957.
Tilly BC, Chalkley GE, van der Knaap JA, Moshkin YM, Kan TW, Dekkers DH, Demmers JA, Verrijzer CP. In vivo analysis reveals that ATP-hydrolysis couples remodeling to SWI/SNF release from chromatin. Elife. 2021 Jul 27;10. doi: 10.7554/eLife.69424. PubMed PMID: 34313222; PubMed Central PMCID: PMC8352592.
Geijer ME, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, Cugusi S, van Toorn M, van der Woude M, Janssens RC, Kok YP, Gong W, Raams A, Lo CSY, Lebbink JHG, Geverts B, Plummer DA, Bezstarosti K, Theil AF, Mitter R, Houtsmuller AB, Vermeulen W, Demmers JAA, Li S, van Vugt MATM, Lans H, Bernards R, Svejstrup JQ, Ray Chaudhuri A, Wyrick JJ, Marteijn JA. Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability. Nat Cell Biol. 2021 Jul;23(7):809. doi: 10.1038/s41556-021-00720-y. PubMed PMID: 34163038; PubMed Central PMCID: PMC8631712.
Lin Z, Wu B, Paul MW, Li KW, Yao Y, Smal I, Proietti Onori M, Hasanbegovic H, Bezstarosti K, Demmers J, Houtsmuller AB, Meijering E, Hoebeek FE, Schonewille M, Smit AB, Gao Z, De Zeeuw CI. Protein Phosphatase 2B Dual Function Facilitates Synaptic Integrity and Motor Learning. J Neurosci. 2021 Jun 30;41(26):5579-5594. doi: 10.1523/JNEUROSCI.1741-20.2021. Epub 2021 May 21. PubMed PMID: 34021041; PubMed Central PMCID: PMC8244972.
Geijer ME, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, Cugusi S, van Toorn M, van der Woude M, Janssens RC, Kok YP, Gong W, Raams A, Lo CSY, Lebbink JHG, Geverts B, Plummer DA, Bezstarosti K, Theil AF, Mitter R, Houtsmuller AB, Vermeulen W, Demmers JAA, Li S, van Vugt MATM, Lans H, Bernards R, Svejstrup JQ, Ray Chaudhuri A, Wyrick JJ, Marteijn JA. Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability. Nat Cell Biol. 2021 Jun;23(6):608-619. doi: 10.1038/s41556-021-00692-z. Epub 2021 Jun 9. PubMed PMID: 34108662; PubMed Central PMCID: PMC7611218.
Vaes N, Schonkeren SL, Rademakers G, Holland AM, Koch A, Gijbels MJ, Keulers TG, de Wit M, Moonen L, Van der Meer JRM, van den Boezem E, Wolfs TGAM, Threadgill DW, Demmers J, Fijneman RJA, Jimenez CR, Vanden Berghe P, Smits KM, Rouschop KMA, Boesmans W, Hofstra RMW, Melotte V. Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2. EMBO Rep. 2021 Jun 4;22(6):e51913. doi: 10.15252/embr.202051913. Epub 2021 Apr 23. PubMed PMID: 33890711; PubMed Central PMCID: PMC8183412.
Goulielmaki E, Tsekrekou M, Batsiotos N, Ascensão-Ferreira M, Ledaki E, Stratigi K, Chatzinikolaou G, Topalis P, Kosteas T, Altmüller J, Demmers JA, Barbosa-Morais NL, Garinis GA. The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing. Nat Commun. 2021 May 26;12(1):3153. doi: 10.1038/s41467-021-23505-1. PubMed PMID: 34039990; PubMed Central PMCID: PMC8155215.
Bouzid R, de Beijer MTA, Luijten RJ, Bezstarosti K, Kessler AL, Bruno MJ, Peppelenbosch MP, Demmers JAA, Buschow SI. Empirical Evaluation of the Use of Computational HLA Binding as an Early Filter to the Mass Spectrometry-Based Epitope Discovery Workflow. Cancers (Basel). 2021 May 12;13(10). doi: 10.3390/cancers13102307. PubMed PMID: 34065814; PubMed Central PMCID: PMC8150281.
Lo CSY, van Toorn M, Gaggioli V, Paes Dias M, Zhu Y, Manolika EM, Zhao W, van der Does M, Mukherjee C, G S C Souto Gonçalves J, van Royen ME, French PJ, Demmers J, Smal I, Lans H, Wheeler D, Jonkers J, Chaudhuri AR, Marteijn JA, Taneja N. SMARCAD1-mediated active replication fork stability maintains genome integrity. Sci Adv. 2021 May;7(19). doi: 10.1126/sciadv.abe7804. Print 2021 May. PubMed PMID: 33952518; PubMed Central PMCID: PMC8099181.
Lamers MM, van der Vaart J, Knoops K, Riesebosch S, Breugem TI, Mykytyn AZ, Beumer J, Schipper D, Bezstarosti K, Koopman CD, Groen N, Ravelli RBG, Duimel HQ, Demmers JAA, Verjans GMGM, Koopmans MPG, Muraro MJ, Peters PJ, Clevers H, Haagmans BL. An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells. EMBO J. 2021 Mar 1;40(5):e105912. doi: 10.15252/embj.2020105912. Epub 2021 Jan 11. PubMed PMID: 33283287; PubMed Central PMCID: PMC7883112.
Avagliano Trezza R, Punt AM, Mientjes E, van den Berg M, Zampeta FI, de Graaf IJ, van der Weegen Y, Demmers JAA, Elgersma Y, Distel B. Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function. Sci Rep. 2021 Feb 4;11(1):3007. doi: 10.1038/s41598-021-82319-9. PubMed PMID: 33542309; PubMed Central PMCID: PMC7862399.
Sap KA, Guler AT, Bury A, Dekkers D, Demmers JAA, Reits EA. Identification of Full-Length Wild-Type and Mutant Huntingtin Interacting Proteins by Crosslinking Immunoprecipitation in Mice Brain Cortex. J Huntingtons Dis. 2021;10(3):335-347. doi: 10.3233/JHD-210476. PubMed PMID: 34151850; PubMed Central PMCID: PMC8609692.
Scheenstra MR, Martínez-Botía P, Acebes-Huerta A, Brouwer RWW, Caballero-Sánchez N, Gillemans N, De Bleser P, Nota B, De Cuyper IM, Salunkhe V, Woltman AM, van de Laar L, Rijkers E, Demmers JAA, van IJcken WFJ, Philipsen S, van den Berg TK, Kuijpers TW, Gutiérrez L. Comparison of the PU.1 transcriptional regulome and interactome in human and mouse inflammatory dendritic cells. J Leukoc Biol. 2020 Dec 2;. doi: 10.1002/JLB.6A1219-711RRR. [Epub ahead of print] PubMed PMID: 33289106.
Miyata M, Gillemans N, Hockman D, Demmers JAA, Cheng JF, Hou J, Salminen M, Fisher CA, Taylor S, Gibbons RJ, Ganis JJ, Zon LI, Grosveld F, Mulugeta E, Sauka-Spengler T, Higgs DR, Philipsen S. An evolutionarily ancient mechanism for regulation of hemoglobin expression in vertebrate red cells. Blood. 2020 Jul 16;136(3):269-278. doi: 10.1182/blood.2020004826. PubMed PMID: 32396940; PubMed Central PMCID: PMC7531998.
Saha C, Mohanraju P, Stubbs A, Dugar G, Hoogstrate Y, Kremers GJ, van Cappellen WA, Horst-Kreft D, Laffeber C, Lebbink JHG, Bruens S, Gaskin D, Beerens D, Klunder M, Joosten R, Demmers JAA, van Gent D, Mouton JW, van der Spek PJ, van der Oost J, van Baarlen P, Louwen R. Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA. Sci Adv. 2020 Jun;6(25):eaaz4849. doi: 10.1126/sciadv.aaz4849. eCollection 2020 Jun. PubMed PMID: 32596446; PubMed Central PMCID: PMC7299616.
van Dijk CGM, Louzao-Martinez L, van Mulligen E, Boermans B, Demmers JAA, van den Bosch TPP, Goumans MJ, Duncker DJ, Verhaar MC, Cheng C. Extracellular Matrix Analysis of Human Renal Arteries in Both Quiescent and Active Vascular State. Int J Mol Sci. 2020 May 30;21(11). doi: 10.3390/ijms21113905. PubMed PMID: 32486169; PubMed Central PMCID: PMC7313045.
Mandemaker IK, Zhou D, Bruens ST, Dekkers DH, Verschure PJ, Edupuganti RR, Meshorer E, Demmers JAA, Marteijn JA. Histone H1 eviction by the histone chaperone SET reduces cell survival following DNA damage. J Cell Sci. 2020 May 11;133(9). doi: 10.1242/jcs.235473. PubMed PMID: 32184266.
Bezstarosti K, van der Wal L, Demmers JAA. Detection of Protein Ubiquitination Sites by Peptide Enrichment and Mass Spectrometry. J Vis Exp. 2020 Mar 23;(157). doi: 10.3791/59079. PubMed PMID: 32250355.
André LM, van Cruchten RTP, Willemse M, Bezstarosti K, Demmers JAA, van Agtmaal EL, Wansink DG, Wieringa B. Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG)n Repeat. Int J Mol Sci. 2019 Nov 13;20(22). doi: 10.3390/ijms20225685. PubMed PMID: 31766224; PubMed Central PMCID: PMC6888582.
Louzao-Martinez L, van Dijk CGM, Xu YJ, Korn A, Bekker NJ, Brouwhuis R, Nicese MN, Demmers JAA, Goumans MTH, Masereeuw R, Duncker DJ, Verhaar MC, Cheng C. A proteome comparison between human fetal and mature renal extracellular matrix identifies EMILIN1 as a regulator of renal epithelial cell adhesion. Matrix Biol Plus. 2019 Nov;4:100011. doi: 10.1016/j.mbplus.2019.100011. eCollection 2019 Nov. PubMed PMID: 33543009; PubMed Central PMCID: PMC7852202.
Magini P, Smits DJ, Vandervore L, Schot R, Columbaro M, Kasteleijn E, van der Ent M, Palombo F, Lequin MH, Dremmen M, de Wit MCY, Severino M, Divizia MT, Striano P, Ordonez-Herrera N, Alhashem A, Al Fares A, Al Ghamdi M, Rolfs A, Bauer P, Demmers J, Verheijen FW, Wilke M, van Slegtenhorst M, van der Spek PJ, Seri M, Jansen AC, Stottmann RW, Hufnagel RB, Hopkin RJ, Aljeaid D, Wiszniewski W, Gawlinski P, Laure-Kamionowska M, Alkuraya FS, Akleh H, Stanley V, Musaev D, Gleeson JG, Zaki MS, Brunetti-Pierri N, Cappuccio G, Davidov B, Basel-Salmon L, Bazak L, Shahar NR, Bertoli-Avella A, Mirzaa GM, Dobyns WB, Pippucci T, Fornerod M, Mancini GMS. Loss of SMPD4 Causes a Developmental Disorder Characterized by Microcephaly and Congenital Arthrogryposis. Am J Hum Genet. 2019 Oct 3;105(4):689-705. doi: 10.1016/j.ajhg.2019.08.006. Epub 2019 Sep 5. PubMed PMID: 31495489; PubMed Central PMCID: PMC6817560.
Sap KA, Guler AT, Bezstarosti K, Bury AE, Juenemann K, Demmers JA, Reits EA. Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains. Mol Cell Proteomics. 2019 Sep;18(9):1705-1720. doi: 10.1074/mcp.RA119.001486. Epub 2019 May 28. PubMed PMID: 31138642; PubMed Central PMCID: PMC6731087.
Konietzny A, González-Gallego J, Bär J, Perez-Alvarez A, Drakew A, Demmers JAA, Dekkers DHW, Hammer JA 3rd, Frotscher M, Oertner TG, Wagner W, Kneussel M, Mikhaylova M. Myosin V regulates synaptopodin clustering and localization in the dendrites of hippocampal neurons. J Cell Sci. 2019 Aug 22;132(16). doi: 10.1242/jcs.230177. PubMed PMID: 31371487; PubMed Central PMCID: PMC6737913.
Mukherjee C, Tripathi V, Manolika EM, Heijink AM, Ricci G, Merzouk S, de Boer HR, Demmers J, van Vugt MATM, Ray Chaudhuri A. RIF1 promotes replication fork protection and efficient restart to maintain genome stability. Nat Commun. 2019 Jul 23;10(1):3287. doi: 10.1038/s41467-019-11246-1. PubMed PMID: 31337767; PubMed Central PMCID: PMC6650494.
Quevedo M, Meert L, Dekker MR, Dekkers DHW, Brandsma JH, van den Berg DLC, Ozgür Z, van IJcken WFJ, Demmers J, Fornerod M, Poot RA. Publisher Correction: Mediator complex interaction partners organize the transcriptional network that defines neural stem cells. Nat Commun. 2019 Jul 22;10(1):3318. doi: 10.1038/s41467-019-11254-1. PubMed PMID: 31332183; PubMed Central PMCID: PMC6646368.
van de Vlekkert D, Demmers J, Nguyen XX, Campos Y, Machado E, Annunziata I, Hu H, Gomero E, Qiu X, Bongiovanni A, Feghali-Bostwick CA, d'Azzo A. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Sci Adv. 2019 Jul;5(7):eaav3270. doi: 10.1126/sciadv.aav3270. eCollection 2019 Jul. PubMed PMID: 31328155; PubMed Central PMCID: PMC6636989.
Kool MJ, Proietti Onori M, Borgesius NZ, van de Bree JE, Elgersma-Hooisma M, Nio E, Bezstarosti K, Buitendijk GHS, Aghadavoud Jolfaei M, Demmers JAA, Elgersma Y, van Woerden GM. CAMK2-Dependent Signaling in Neurons Is Essential for Survival. J Neurosci. 2019 Jul 10;39(28):5424-5439. doi: 10.1523/JNEUROSCI.1341-18.2019. Epub 2019 May 7. PubMed PMID: 31064859; PubMed Central PMCID: PMC6616294.
Brandsma I, Sato K, van Rossum-Fikkert SE, van Vliet N, Sleddens E, Reuter M, Odijk H, van den Tempel N, Dekkers DHW, Bezstarosti K, Demmers JAA, Maas A, Lebbink J, Wyman C, Essers J, van Gent DC, Baarends WM, Knipscheer P, Kanaar R, Zelensky AN. HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis. Cell Rep. 2019 Jun 25;27(13):3790-3798.e7. doi: 10.1016/j.celrep.2019.05.096. PubMed PMID: 31242413.
Quevedo M, Meert L, Dekker MR, Dekkers DHW, Brandsma JH, van den Berg DLC, Ozgür Z, van IJcken WFJ, Demmers J, Fornerod M, Poot RA. Mediator complex interaction partners organize the transcriptional network that defines neural stem cells. Nat Commun. 2019 Jun 17;10(1):2669. doi: 10.1038/s41467-019-10502-8. PubMed PMID: 31209209; PubMed Central PMCID: PMC6573065.
van Coevorden-Hameete MH, de Bruijn MAAM, de Graaff E, Bastiaansen DAEM, Schreurs MWJ, Demmers JAA, Ramberger M, Hulsenboom ESP, Nagtzaam MMP, Boukhrissi S, Veldink JH, Verschuuren JJGM, Hoogenraad CC, Sillevis Smitt PAE, Titulaer MJ. The expanded clinical spectrum of anti-GABABR encephalitis and added value of KCTD16 autoantibodies. Brain. 2019 Jun 1;142(6):1631-1643. doi: 10.1093/brain/awz094. PubMed PMID: 31009048; PubMed Central PMCID: PMC6536844.
Wienholz F, Zhou D, Turkyilmaz Y, Schwertman P, Tresini M, Pines A, van Toorn M, Bezstarosti K, Demmers JAA, Marteijn JA. FACT subunit Spt16 controls UVSSA recruitment to lesion-stalled RNA Pol II and stimulates TC-NER. Nucleic Acids Res. 2019 May 7;47(8):4011-4025. doi: 10.1093/nar/gkz055. PubMed PMID: 30715484; PubMed Central PMCID: PMC6486547.
Oosterhof N, Chang IJ, Karimiani EG, Kuil LE, Jensen DM, Daza R, Young E, Astle L, van der Linde HC, Shivaram GM, Demmers J, Latimer CS, Keene CD, Loter E, Maroofian R, van Ham TJ, Hevner RF, Bennett JT. Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia. Am J Hum Genet. 2019 May 2;104(5):936-947. doi: 10.1016/j.ajhg.2019.03.010. Epub 2019 Apr 11. PubMed PMID: 30982608; PubMed Central PMCID: PMC6506793.
Vandervore LV, Schot R, Kasteleijn E, Oegema R, Stouffs K, Gheldof A, Grochowska MM, van der Sterre MLT, van Unen LMA, Wilke M, Elfferich P, van der Spek PJ, Heijsman D, Grandone A, Demmers JAA, Dekkers DHW, Slotman JA, Kremers GJ, Schaaf GJ, Masius RG, van Essen AJ, Rump P, van Haeringen A, Peeters E, Altunoglu U, Kalayci T, Poot RA, Dobyns WB, Bahi-Buisson N, Verheijen FW, Jansen AC, Mancini GMS. Heterogeneous clinical phenotypes and cerebral malformations reflected by rotatin cellular dynamics. Brain. 2019 Apr 1;142(4):867-884. doi: 10.1093/brain/awz045. PubMed PMID: 30879067; PubMed Central PMCID: PMC6439326.
van den Tempel N, Zelensky AN, Odijk H, Laffeber C, Schmidt CK, Brandsma I, Demmers J, Krawczyk PM, Kanaar R. On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation. Cancers (Basel). 2019 Jan 15;11(1). doi: 10.3390/cancers11010097. PubMed PMID: 30650591; PubMed Central PMCID: PMC6356811.
Kenter AT, van Rossum-Fikkert SE, Salih M, Verhagen PCMS, van Leenders GJLH, Demmers JAA, Jansen G, Gribnau J, Zietse R, Hoorn EJ. Identifying cystogenic paracrine signaling molecules in cyst fluid of patients with polycystic kidney disease. Am J Physiol Renal Physiol. 2019 Jan 1;316(1):F204-F213. doi: 10.1152/ajprenal.00470.2018. Epub 2018 Nov 7. PubMed PMID: 30403162.
Gontan C, Mira-Bontenbal H, Magaraki A, Dupont C, Barakat TS, Rentmeester E, Demmers J, Gribnau J. REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice. Nat Commun. 2018 Nov 12;9(1):4752. doi: 10.1038/s41467-018-07060-w. PubMed PMID: 30420655; PubMed Central PMCID: PMC6232137.
van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane EG, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz HC, Kanaar R, Essers J. Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation. Cardiovasc Res. 2018 Nov 1;114(13):1776-1793. doi: 10.1093/cvr/cvy150. PubMed PMID: 29931197; PubMed Central PMCID: PMC6198735.
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