My Bibliography

select

Li L, Miao J, Chu D, Jin N, Tung YC, Dai CL, Hu W, Gong CX, Iqbal K, Liu F. Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation. CNS Neurosci Ther. 2022 Dec;28(12):2245-2259. doi: 10.1111/cns.13970. Epub 2022 Sep 17. PubMed PMID: 36114722; PubMed Central PMCID: PMC9627375.

select

Hu W, Dai CL, Niu J, Iqbal K. Heightened Tameness and Accelerated Handling-Habituation in 3×Tg-AD Mice on a B6;129 Genetic Background. J Alzheimers Dis Rep. 2022;6(1):245-255. doi: 10.3233/ADR-220007. eCollection 2022. PubMed PMID: 35719714; PubMed Central PMCID: PMC9198767.

select

Hu W, Liu F, Gong CX, Iqbal K. Does proteopathic tau propagate trans-synaptically in the brain?. Mol Neurodegener. 2022 Mar 16;17(1):21. doi: 10.1186/s13024-022-00527-x. PubMed PMID: 35296344; PubMed Central PMCID: PMC8925219.

select

Wu R, Gu J, Zhou D, Tung YC, Jin N, Chu D, Hu W, Wegiel J, Gong CX, Iqbal K, Liu F. Seeding-Competent Tau in Gray Matter Versus White Matter of Alzheimer's Disease Brain. J Alzheimers Dis. 2021;79(4):1647-1659. doi: 10.3233/JAD-201290. PubMed PMID: 33459649.

select

Niu J, Iqbal K, Liu F, Hu W. Rats Display Sexual Dimorphism in Phosphorylation of Brain Tau with Age. J Alzheimers Dis. 2021;82(2):855-869. doi: 10.3233/JAD-210341. PubMed PMID: 34092647.

select

Zhang T, Niu J, Wang Y, Yan J, Hu W, Mi D. The role of C-afferents in mediating neurogenic vasodilatation in plantar skin after acute sciatic nerve injury in rats. BMC Neurosci. 2020 Apr 16;21(1):15. doi: 10.1186/s12868-020-00564-6. PubMed PMID: 32299361; PubMed Central PMCID: PMC7161243.

select

Gu J, Hu W, Tan X, Qu S, Chu D, Gong CX, Iqbal K, Liu F. Elevation of casein kinase 1ε associated with TDP-43 and tau pathologies in Alzheimer's disease. Brain Pathol. 2020 Mar;30(2):283-297. doi: 10.1111/bpa.12775. Epub 2019 Aug 22. PubMed PMID: 31376192; PubMed Central PMCID: PMC8018014.

select

Zhou R, Hu W, Dai CL, Gong CX, Iqbal K, Zhu D, Liu F. Expression of Microtubule Associated Protein Tau in Mouse Pancreatic Islets Is Restricted to Autonomic Nerve Fibers. J Alzheimers Dis. 2020;75(4):1339-1349. doi: 10.3233/JAD-200101. PubMed PMID: 32417779.

select

Wang XS, Chen X, Gu TW, Wang YX, Mi DG, Hu W. Axonotmesis-evoked plantar vasodilatation as a novel assessment of C-fiber afferent function after sciatic nerve injury in rats. Neural Regen Res. 2019 Dec;14(12):2164-2172. doi: 10.4103/1673-5374.262595. PubMed PMID: 31397356; PubMed Central PMCID: PMC6788242.

select

Li L, Jiang Y, Hu W, Tung YC, Dai C, Chu D, Gong CX, Iqbal K, Liu F. Pathological Alterations of Tau in Alzheimer's Disease and 3xTg-AD Mouse Brains. Mol Neurobiol. 2019 Sep;56(9):6168-6183. doi: 10.1007/s12035-019-1507-4. Epub 2019 Feb 8. PubMed PMID: 30734228.

select

Iqbal K, Liu F, Gong C, Dai C, Hu W. Why delay in effective treatment for Alzheimer's disease and related conditions. Prog Mol Biol Transl Sci. 2019;168:243-256. doi: 10.1016/bs.pmbts.2019.08.002. Epub 2019 Aug 30. Review. PubMed PMID: 31699318.

select

Mi D, Yuan Y, Zhang Y, Niu J, Wang Y, Yan J, Yang Y, Hu W. Injection of Fluoro-Gold into the tibial nerve leads to prolonged but reversible functional deficits in rats. Sci Rep. 2019 Jul 9;9(1):9906. doi: 10.1038/s41598-019-46285-7. PubMed PMID: 31289330; PubMed Central PMCID: PMC6616333.

select

Zhang Y, Wu F, Iqbal K, Gong CX, Hu W, Liu F. Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice. Sci Rep. 2019 Mar 7;9(1):3789. doi: 10.1038/s41598-019-40678-4. PubMed PMID: 30846870; PubMed Central PMCID: PMC6405988.

select

Miao J, Shi R, Li L, Chen F, Zhou Y, Tung YC, Hu W, Gong CX, Iqbal K, Liu F. Pathological Tau From Alzheimer's Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo. Front Aging Neurosci. 2019;11:34. doi: 10.3389/fnagi.2019.00034. eCollection 2019. PubMed PMID: 30890929; PubMed Central PMCID: PMC6411797.

select

Liu D, Mi D, Zhang T, Zhang Y, Yan J, Wang Y, Tan X, Yuan Y, Yang Y, Gu X, Hu W. Tubulation repair mitigates misdirection of regenerating motor axons across a sciatic nerve gap in rats. Sci Rep. 2018 Feb 21;8(1):3443. doi: 10.1038/s41598-018-21652-y. PubMed PMID: 29467542; PubMed Central PMCID: PMC5821835.

select

Zhou Y, Shi J, Chu D, Hu W, Guan Z, Gong CX, Iqbal K, Liu F. Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer's Disease. Front Aging Neurosci. 2018;10:27. doi: 10.3389/fnagi.2018.00027. eCollection 2018. PubMed PMID: 29472853; PubMed Central PMCID: PMC5810298.

select

Gu J, Wang W, Miao S, Chen F, Wu F, Hu W, Iqbal K, Gong CX, Liu F. Protein Phosphatase 1 dephosphorylates TDP-43 and suppresses its function in tau exon 10 inclusion. FEBS Lett. 2018 Feb;592(3):402-410. doi: 10.1002/1873-3468.12976. Epub 2018 Jan 26. PubMed PMID: 29334120.

select

Dai CL, Hu W, Tung YC, Liu F, Gong CX, Iqbal K. Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice. Alzheimers Res Ther. 2018 Jan 31;10(1):13. doi: 10.1186/s13195-018-0341-7. PubMed PMID: 29386065; PubMed Central PMCID: PMC5793372.

select

Hu W, Tung YC, Zhang Y, Liu F, Iqbal K. Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain Injury. J Alzheimers Dis. 2018;64(3):709-722. doi: 10.3233/JAD-180177. PubMed PMID: 29889065; PubMed Central PMCID: PMC6087458.

select

Li Y, Chen Y, Tan L, Pan JY, Lin WW, Wu J, Hu W, Chen X, Wang XD. RNAi-mediated ephrin-B2 silencing attenuates astroglial-fibrotic scar formation and improves spinal cord axon growth. CNS Neurosci Ther. 2017 Oct;23(10):779-789. doi: 10.1111/cns.12723. Epub 2017 Aug 21. PubMed PMID: 28834283; PubMed Central PMCID: PMC6492699.

select

Hu W, Wu F, Zhang Y, Gong CX, Iqbal K, Liu F. Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis. Front Aging Neurosci. 2017;9:311. doi: 10.3389/fnagi.2017.00311. eCollection 2017. PubMed PMID: 29021756; PubMed Central PMCID: PMC5623682.

select

Gu J, Wu F, Xu W, Shi J, Hu W, Jin N, Qian W, Wang X, Iqbal K, Gong CX, Liu F. TDP-43 suppresses tau expression via promoting its mRNA instability. Nucleic Acids Res. 2017 Jun 2;45(10):6177-6193. doi: 10.1093/nar/gkx175. PubMed PMID: 28335005; PubMed Central PMCID: PMC5449590.

select

Erratum. Alzheimers Dement. 2017 Apr;13(4):498. doi: 10.1016/j.jalz.2017.03.004. PubMed PMID: 28400031.

select

Hu W, Zhang X, Tung YC, Xie S, Liu F, Iqbal K. Hyperphosphorylation determines both the spread and the morphology of tau pathology. Alzheimers Dement. 2016 Oct;12(10):1066-1077. doi: 10.1016/j.jalz.2016.01.014. Epub 2016 Apr 28. PubMed PMID: 27133892.

select

Wang Y, Zhang Y, Hu W, Xie S, Gong CX, Iqbal K, Liu F. Corrigendum: Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation. Sci Rep. 2016 Jan 7;6:17241. doi: 10.1038/srep17241. PubMed PMID: 26738441; PubMed Central PMCID: PMC4704067.

select

Wang Y, Zhao Y, Sun C, Hu W, Zhao J, Li G, Zhang L, Liu M, Liu Y, Ding F, Yang Y, Gu X. Chitosan Degradation Products Promote Nerve Regeneration by Stimulating Schwann Cell Proliferation via miR-27a/FOXO1 Axis. Mol Neurobiol. 2016 Jan;53(1):28-39. doi: 10.1007/s12035-014-8968-2. Epub 2014 Nov 18. PubMed PMID: 25399953.

select

Deng A, Liu D, Gu C, Gu X, Gu J, Hu W. Active skin perfusion and thermoregulatory response in the hand following nerve injury and repair in human upper extremities. Brain Res. 2016 Jan 1;1630:38-49. doi: 10.1016/j.brainres.2015.10.045. Epub 2015 Oct 31. PubMed PMID: 26529641.

select

Wang Y, Zhang Y, Hu W, Xie S, Gong CX, Iqbal K, Liu F. Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation. Sci Rep. 2015 Oct 29;5:15709. doi: 10.1038/srep15709. PubMed PMID: 26511732; PubMed Central PMCID: PMC4625177.

select

Bai X, Wang Y, Man L, Zhang Q, Sun C, Hu W, Liu Y, Liu M, Gu X, Wang Y. CD59 mediates cartilage patterning during spontaneous tail regeneration. Sci Rep. 2015 Aug 4;5:12798. doi: 10.1038/srep12798. PubMed PMID: 26238652; PubMed Central PMCID: PMC4523838.

select

Li S, Wang X, Gu Y, Chen C, Wang Y, Liu J, Hu W, Yu B, Wang Y, Ding F, Liu Y, Gu X. Let-7 microRNAs regenerate peripheral nerve regeneration by targeting nerve growth factor. Mol Ther. 2015 Mar;23(3):423-33. doi: 10.1038/mt.2014.220. Epub 2014 Nov 14. PubMed PMID: 25394845; PubMed Central PMCID: PMC4351454.

select

Wang Y, Wang H, Mi D, Gu X, Hu W. Periodical assessment of electrophysiological recovery following sciatic nerve crush via surface stimulation in rats. Neurol Sci. 2015 Mar;36(3):449-56. doi: 10.1007/s10072-014-2005-0. Epub 2014 Nov 14. PubMed PMID: 25394740.

select

Zhou S, Gao R, Hu W, Qian T, Wang N, Ding G, Ding F, Yu B, Gu X. MiR-9 inhibits Schwann cell migration by targeting Cthrc1 following sciatic nerve injury. J Cell Sci. 2014 Mar 1;127(Pt 5):967-76. doi: 10.1242/jcs.131672. Epub 2014 Jan 10. PubMed PMID: 24413174.

select

Zhang Y, Hu Y, Liu D, Zhao Y, Hu W. [Regeneration speed of sensory nerve fibers across sciatic nerve defects in varying length within a guidance conduit in rats]. Chinese Journal of Anatomy. 2014; 37(3):343-347.

select

Mi D, Zhang Y, Gu T, Zhao Y, Hu W. [Long-term evaluation of functional recovery and nerve regeneration following tubulation repair of nerve defects in mice]. Acta Anatomica Sinica. 2014; 45(5):599-604.

select

Hu W, Liu D, Zhang Y, Shen Z, Gu T, Gu X, Gu J. Neurological function following intra-neural injection of fluorescent neuronal tracers in rats. Neural Regen Res. 2013 May 15;8(14):1253-61. doi: 10.3969/j.issn.1673-5374.2013.14.001. PubMed PMID: 25206419; PubMed Central PMCID: PMC4107650.

select

Yu B, Zhou S, Hu W, Qian T, Gao R, Ding G, Ding F, Gu X. Altered long noncoding RNA expressions in dorsal root ganglion after rat sciatic nerve injury. Neurosci Lett. 2013 Feb 8;534:117-22. doi: 10.1016/j.neulet.2012.12.014. Epub 2012 Dec 26. PubMed PMID: 23274483.

select

Liu D, Zhang Y, Mi D, Gu J, Hu W. [A rat model of sciatic nerve deafferentation: anatomy, tracing and surgery]. Chinese Journal of Hand Surgery. 2013; 29(4):201-204.

select

Liu D, Hu W, Zhang Y, Deng A, Gu J. [Comparison on the efficacy of different retrograde tracers for the spinal motor neurons in rats]. Chinese Journal of Anatomy. 2013; 36(3):350-352.

select

Shen Z, Gu T, Hu W. [Time-lapse LDPI analysis of skin territory following sciatic nerve transection in rats]. Acta Universitatis Medicinalis Nanjing (Natural Science). 2013; 33:779-783.

select

Gu J, Hu W, Deng A, Zhao Q, Lu S, Gu X. Surgical repair of a 30 mm long human median nerve defect in the distal forearm by implantation of a chitosan-PGA nerve guidance conduit. J Tissue Eng Regen Med. 2012 Feb;6(2):163-8. doi: 10.1002/term.407. Epub 2011 Mar 3. PubMed PMID: 21370489.

select

Hu W, Yang M, Chang J, Shen Z, Gu T, Deng A, Gu X. Laser doppler perfusion imaging of skin territory to reflect autonomic functional recovery following sciatic nerve autografting repair in rats. Microsurgery. 2012 Feb;32(2):136-43. doi: 10.1002/micr.20974. Epub 2012 Jan 20. PubMed PMID: 22262542.

select

Gu J, Wang H, Hu W, Zhao W, Yang Y. [Sciatic nerve repair across a 10-mm defect bridged by a chitosan conduit reinforced with nerve growth factor in rats]. Medical Journal of Communications. 2012; 24(1):13-15.

select

Gu C, Hu W, Deng A, Gu X, Gu J. [A preliminary study on skin blood perfusion following median nerve transection at wrist in adult human patients]. Journal of Nantong University (Medical Sciences). 2012; 32(3):177-179.

select

Hu W, Wang Y, Liu D, Gu X. [Volume conduction in the electrophysiological assessment of acute sciatic nerve crush in rats]. Journal of Nantong University (Medical Sciences). 2012; 32(1):7-12.

select

Qian W, Yin X, Hu W, Shi J, Gu J, Grundke-Iqbal I, Iqbal K, Gong CX, Liu F. Activation of protein phosphatase 2B and hyperphosphorylation of Tau in Alzheimer's disease. J Alzheimers Dis. 2011;23(4):617-27. doi: 10.3233/JAD-2010-100987. PubMed PMID: 21157033; PubMed Central PMCID: PMC3377165.

select

Ding F, Wu J, Yang Y, Hu W, Zhu Q, Tang X, Liu J, Gu X. Use of tissue-engineered nerve grafts consisting of a chitosan/poly(lactic-co-glycolic acid)-based scaffold included with bone marrow mesenchymal cells for bridging 50-mm dog sciatic nerve gaps. Tissue Eng Part A. 2010 Dec;16(12):3779-90. doi: 10.1089/ten.TEA.2010.0299. Epub 2010 Sep 6. PubMed PMID: 20666610.

select

Hu W, Gu J, Deng A, Gu X. Polyglycolic acid filaments guide Schwann cell migration in vitro and in vivo. Biotechnol Lett. 2008 Nov;30(11):1937-42. doi: 10.1007/s10529-008-9795-1. Epub 2008 Jul 9. PubMed PMID: 18612593.

select

Fan W, Gu J, Hu W, Deng A, Ma Y, Liu J, Ding F, Gu X. Repairing a 35-mm-long median nerve defect with a chitosan/PGA artificial nerve graft in the human: a case study. Microsurgery. 2008;28(4):238-42. doi: 10.1002/micr.20488. PubMed PMID: 18383350.

select

Yang Y, Ding F, Wu J, Hu W, Liu W, Liu J, Gu X. Development and evaluation of silk fibroin-based nerve grafts used for peripheral nerve regeneration. Biomaterials. 2007 Dec;28(36):5526-35. doi: 10.1016/j.biomaterials.2007.09.001. Epub 2007 Sep 19. PubMed PMID: 17884161.

select

Yang YM, Hu W, Wang XD, Gu XS. The controlling biodegradation of chitosan fibers by N-acetylation in vitro and in vivo. J Mater Sci Mater Med. 2007 Nov;18(11):2117-21. doi: 10.1007/s10856-007-3013-x. Epub 2007 Jul 10. PubMed PMID: 17619982.