Distinct structural mechanisms drive gain-of-function activation of TMEM16E in gnathodiaphyseal dysplasia. [Preprint]. 2026 September. doi: 10.21203/rs.3.rs-10425456/v1.
Structural resolution of Org34167 inhibition of HCN1 channels.
Biophysical Society; 2026 February 19; Biophysical journal; c2026.
Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel.
Nat Commun.
2025 Feb 19;16(1):1769. doi: 10.1038/s41467-025-56844-4. PubMed PMID:
39971906; PubMed Central PMCID:
PMC11840039.
Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants.
Nature.
2024 Aug;632(8024):451-459. doi: 10.1038/s41586-024-07743-z. Epub 2024 Jul 31. PubMed PMID:
39085604; PubMed Central PMCID:
PMC11634041.
A pentameric TRPV3 channel with a dilated pore.
Nature.
2023 Sep;621(7977):206-214. doi: 10.1038/s41586-023-06470-1. Epub 2023 Aug 30. PubMed PMID:
37648856; PubMed Central PMCID:
PMC10584365.
Allostery in proteins: canonical models and new insights.
In:
Lennarz WJ, editor.
Encyclopedia of Biological Chemistry
3 ed. Oxford: Elsevier; 2021. Chapter 3; p.27-43.
Protein Function | Allostery in Proteins: Canonical Models and New Insights.
In:
Encyclopedia of Biological Chemistry III
[Internet]
Elsevier; 2021. 27-43p.
Available from: https://linkinghub.elsevier.com/retrieve/pii/B9780128194607002590.
Small molecule allosteric uncoupling of microtubule depolymerase activity from motility in human Kinesin-5 during mitotic spindle assembly.
Sci Rep.
2019 Dec 27;9(1):19900. doi: 10.1038/s41598-019-56173-9. PubMed PMID:
31882607; PubMed Central PMCID:
PMC6934681.
In silico modeling of the cryptic E2∼ubiquitin-binding site of E6-associated protein (E6AP)/UBE3A reveals the mechanism of polyubiquitin chain assembly.
J Biol Chem.
2017 Nov 3;292(44):18006-18023. doi: 10.1074/jbc.M117.813477. Epub 2017 Sep 18. PubMed PMID:
28924046; PubMed Central PMCID:
PMC5672028.
Allostery Wiring Map for Kinesin Energy Transduction and Its Evolution.
J Biol Chem.
2016 Sep 30;291(40):20932-20945. doi: 10.1074/jbc.M116.733675. Epub 2016 Aug 8. PubMed PMID:
27507814; PubMed Central PMCID:
PMC5076506.
Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core.
J Biol Chem.
2010 Jun 11;285(24):18650-61. doi: 10.1074/jbc.M109.092072. Epub 2010 Mar 18. PubMed PMID:
20299460; PubMed Central PMCID:
PMC2881790.
A direct visual and motor neural interface demonstration in a rat.
Proceedings from the 3rd International IEEE Engineering in Medicine and Biology Conference on Neural Engineering; 2007; Kohala Coast, HI. c2007.
Linear electrode depth estimation in a rat motor cortex by laminar analysis of ketamine-xylazine induced oscillations.
Proceedings from the 3rd International IEEE Engineering in Medicine and Biology Conference on Neural Engineering; 2007; Kohala Coast, HI. c2007.
Linear Electrode Depth Estimation in Rat Motor Cortex by Laminar Analysis of Ketamine-Xylazine-Induced Oscillations.
2007 3rd International IEEE/EMBS Conference on Neural Engineering. 2007 3rd International IEEE/EMBS Conference on Neural Engineering; ; Kohala Coast, HI. IEEE; c2007.
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