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Accardi A, Zanni E, Alvarenga O, Rychlik N, Feng Z, Kim E, Khelashvili G. Distinct structural mechanisms drive gain-of-function activation of TMEM16E in gnathodiaphyseal dysplasia. [Preprint]. 2026 September. doi: 10.21203/rs.3.rs-10425456/v1.
Kim ED, Forster IC, Reid CA, Nimigean CM. Structural resolution of Org34167 inhibition of HCN1 channels. Biophysical Society; 2026 February 19; Biophysical journal; c2026.
Agarwal S, Kim ED, Lee S, Simon A, Accardi A, Nimigean CM. Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel. Nat Commun. 2025 Feb 19;16(1):1769. doi: 10.1038/s41467-025-56844-4. PubMed PMID: 39971906; PubMed Central PMCID: PMC11840039.
Kim ED, Wu X, Lee S, Tibbs GR, Cunningham KP, Di Zanni E, Perez ME, Goldstein PA, Accardi A, Larsson HP, Nimigean CM. Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants. Nature. 2024 Aug;632(8024):451-459. doi: 10.1038/s41586-024-07743-z. Epub 2024 Jul 31. PubMed PMID: 39085604; PubMed Central PMCID: PMC11634041.
Lansky S, Betancourt JM, Zhang J, Jiang Y, Kim ED, Paknejad N, Nimigean CM, Yuan P, Scheuring S. A pentameric TRPV3 channel with a dilated pore. Nature. 2023 Sep;621(7977):206-214. doi: 10.1038/s41586-023-06470-1. Epub 2023 Aug 30. PubMed PMID: 37648856; PubMed Central PMCID: PMC10584365.
Kim ED, Kim CD, Chaney J, Kim S. Allostery in proteins: canonical models and new insights. In: Lennarz WJ, editor. Encyclopedia of Biological Chemistry 3 ed. Oxford: Elsevier; 2021. Chapter 3; p.27-43.
Kim E, Kim C, Chaney J, Kim S. Protein Function | Allostery in Proteins: Canonical Models and New Insights. In: Encyclopedia of Biological Chemistry III [Internet] Elsevier; 2021. 27-43p. Available from: https://linkinghub.elsevier.com/retrieve/pii/B9780128194607002590.
Kim CD, Kim ED, Liu L, Buckley RS, Parameswaran S, Kim S, Wojcik EJ. Small molecule allosteric uncoupling of microtubule depolymerase activity from motility in human Kinesin-5 during mitotic spindle assembly. Sci Rep. 2019 Dec 27;9(1):19900. doi: 10.1038/s41598-019-56173-9. PubMed PMID: 31882607; PubMed Central PMCID: PMC6934681.
Ronchi VP, Kim ED, Summa CM, Klein JM, Haas AL. In silico modeling of the cryptic E2∼ubiquitin-binding site of E6-associated protein (E6AP)/UBE3A reveals the mechanism of polyubiquitin chain assembly. J Biol Chem. 2017 Nov 3;292(44):18006-18023. doi: 10.1074/jbc.M117.813477. Epub 2017 Sep 18. PubMed PMID: 28924046; PubMed Central PMCID: PMC5672028.
Richard J, Kim ED, Nguyen H, Kim CD, Kim S. Allostery Wiring Map for Kinesin Energy Transduction and Its Evolution. J Biol Chem. 2016 Sep 30;291(40):20932-20945. doi: 10.1074/jbc.M116.733675. Epub 2016 Aug 8. PubMed PMID: 27507814; PubMed Central PMCID: PMC5076506.
Kim ED, Buckley R, Learman S, Richard J, Parke C, Worthylake DK, Wojcik EJ, Walker RA, Kim S. Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core. J Biol Chem. 2010 Jun 11;285(24):18650-61. doi: 10.1074/jbc.M109.092072. Epub 2010 Mar 18. PubMed PMID: 20299460; PubMed Central PMCID: PMC2881790.
Marzullo TC, Kim ED, Lehmkuhle MJ, Kipke DR. A direct visual and motor neural interface demonstration in a rat. Proceedings from the 3rd International IEEE Engineering in Medicine and Biology Conference on Neural Engineering; 2007; Kohala Coast, HI. c2007.
Yazdan-Shahmorad A, Gage GJ, Marzullo TC, Kim ED, Kipke DR. Linear electrode depth estimation in a rat motor cortex by laminar analysis of ketamine-xylazine induced oscillations. Proceedings from the 3rd International IEEE Engineering in Medicine and Biology Conference on Neural Engineering; 2007; Kohala Coast, HI. c2007.
Yazdan-Shahmorad A, Gage G, Marzullo T, Kim E, Kipke D. Linear Electrode Depth Estimation in Rat Motor Cortex by Laminar Analysis of Ketamine-Xylazine-Induced Oscillations. 2007 3rd International IEEE/EMBS Conference on Neural Engineering. 2007 3rd International IEEE/EMBS Conference on Neural Engineering; ; Kohala Coast, HI. IEEE; c2007.
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