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Gupta S, Das BC, Schafmeister CE. Synthesis of a pipecolic acid-based bis-amino acid and its assembly into a spiro ladder oligomer. Org Lett. 2005 Jul 7;7(14):2861-4. doi: 10.1021/ol0507672. PubMed PMID: 15987155.
Liu F, Evans T, Das BC. Synthesis of 2-substituted 2H-chromenes using potassium vinyltrifluoroborates. Tetrahedron Lett. 2008 Mar 3;49(10):1578-1581. doi: 10.1016/j.tetlet.2008.01.008. PubMed PMID: 21753857; PubMed Central PMCID: PMC3132890.
Das BC, Smith ME, Kalpana GV. Design and synthesis of 4-HPR derivatives for rhabdoid tumors. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3805-8. doi: 10.1016/j.bmcl.2008.05.021. Epub 2008 May 9. PubMed PMID: 18515102.
Das BC, Smith ME, Kalpana GV. Design, synthesis of novel peptidomimetic derivatives of 4-HPR for rhabdoid tumors. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4177-80. doi: 10.1016/j.bmcl.2008.05.097. Epub 2008 May 29. PubMed PMID: 18556204.
Das BC, Madhukumar AV, Anguiano J, Kim S, Sinz M, Zvyaga TA, Power EC, Ganellin CR, Mani S. Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR). Bioorg Med Chem Lett. 2008 Jul 15;18(14):3974-7. doi: 10.1016/j.bmcl.2008.06.018. Epub 2008 Jun 10. PubMed PMID: 18583127.
Zhou L, Nguyen AN, Sohal D, Ying Ma J, Pahanish P, Gundabolu K, Hayman J, Chubak A, Mo Y, Bhagat TD, Das B, Kapoun AM, Navas TA, Parmar S, Kambhampati S, Pellagatti A, Braunchweig I, Zhang Y, Wickrema A, Medicherla S, Boultwood J, Platanias LC, Higgins LS, List AF, Bitzer M, Verma A. Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS. Blood. 2008 Oct 15;112(8):3434-43. doi: 10.1182/blood-2008-02-139824. Epub 2008 May 12. PubMed PMID: 18474728; PubMed Central PMCID: PMC2569182.
Torregroza I, Evans T, Das BC. A forward chemical screen using zebrafish embryos with novel 2-substituted 2H-chromene derivatives. Chem Biol Drug Des. 2009 Mar;73(3):339-45. doi: 10.1111/j.1747-0285.2009.00782.x. PubMed PMID: 19207470; PubMed Central PMCID: PMC3133956.
Das BC, Mahalingam SM, Evans T, Kabalka GW, Anguiano J, Hema K. Design and synthesis of (E)-1-((3-ethyl-2,4,4-trimethylcyclohex-2-enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1-enyl)ethanol. Chem Commun (Camb). 2009 Apr 28;(16):2133-5. doi: 10.1039/b823063c. Epub 2009 Mar 9. PubMed PMID: 19360170; PubMed Central PMCID: PMC3140768.
Das BC, Mahalingam SM, Evans T. Design and synthesis of novel pinacolylboronate containing combretastatin 'antimitotic agent' analogues. Tetrahedron Lett. 2009 Jun 24;50(25):3031-3034. doi: 10.1016/j.tetlet.2009.04.003. PubMed PMID: 20037629; PubMed Central PMCID: PMC2791373.
Das BC, Madhukumar AV, Anguiano J, Mani S. Design, synthesis and biological evaluation of 2H-benzo[b][1,4] oxazine derivatives as hypoxia targeted compounds for cancer therapeutics. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4204-6. doi: 10.1016/j.bmcl.2009.05.110. Epub 2009 Jun 2. PubMed PMID: 19515559; PubMed Central PMCID: PMC2882196.
Kotla V, Goel S, Nischal S, Heuck C, Vivek K, Das B, Verma A. Mechanism of action of lenalidomide in hematological malignancies. J Hematol Oncol. 2009 Aug 12;2:36. doi: 10.1186/1756-8722-2-36. Review. PubMed PMID: 19674465; PubMed Central PMCID: PMC2736171.
Das BC, Mahalingam SM, Panda L, Wang B, Campbell P, Evans T. Design and Synthesis of Potential New Apoptosis Agents: Hybrid Compounds Containing Perillyl Alcohol and New Constrained Retinoids. Tetrahedron Lett. 2010 Mar 17;51(11):1462-1466. doi: 10.1016/j.tetlet.2010.01.003. PubMed PMID: 20379349; PubMed Central PMCID: PMC2849109.
Das BC, McCartin K, Liu TC, Peterson RT, Evans T. A forward chemical screen in zebrafish identifies a retinoic acid derivative with receptor specificity. PLoS One. 2010 Apr 2;5(4):e10004. doi: 10.1371/journal.pone.0010004. PubMed PMID: 20368991; PubMed Central PMCID: PMC2848850.
Das BC, Mohapatra S, Campbell PD, Nayak S, Mahalingam SM, Evans T. Synthesis of function-oriented 2-phenyl-2H-chromene derivatives using L-pipecolinic acid and substituted guanidine organocatalysts. Tetrahedron Lett. 2010 May 1;51(19):2567-2570. doi: 10.1016/j.tetlet.2010.02.143. PubMed PMID: 21785516; PubMed Central PMCID: PMC3140427.
Schinke C, Goel S, Bhagat TD, Zhou L, Mo Y, Gallagher R, Kabalka GW, Platanias LC, Verma A, Das B. Design and synthesis of novel derivatives of all-trans retinoic acid demonstrate the combined importance of acid moiety and conjugated double bonds in its binding to PML-RAR-alpha oncogene in acute promyelocytic leukemia. Leuk Lymphoma. 2010 Jun;51(6):1108-14. doi: 10.3109/10428191003786766. PubMed PMID: 20536349; PubMed Central PMCID: PMC4104194.
Bao Y, Weiss LM, Ma YF, Lisanti MP, Tanowitz HB, Das BC, Zheng R, Huang H. Molecular cloning and characterization of mitogen-activated protein kinase 2 in Trypanosoma cruzi. Cell Cycle. 2010 Jul 15;9(14):2888-96. doi: 10.4161/cc.9.14.12372. Epub 2010 Jul 13. PubMed PMID: 20603604; PubMed Central PMCID: PMC3040964.
Koba W, Kim K, Lipton ML, Jelicks L, Das B, Herbst L, Fine E. Imaging devices for use in small animals. Semin Nucl Med. 2011 May;41(3):151-65. doi: 10.1053/j.semnuclmed.2010.12.003. Review. PubMed PMID: 21440693.
Das BC, Tang XY, Sanyal S, Mohapatra S, Rogler P, Nayak S, Evans T. Design and Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazole Containing Retinoids from a Retinoic Acid Receptor Agonist. Tetrahedron Lett. 2011 May 11;52(19):2433-2435. doi: 10.1016/j.tetlet.2011.03.011. PubMed PMID: 21765558; PubMed Central PMCID: PMC3135900.
Jubinsky PT, Short MK, Ghanem M, Das BC. Design, synthesis, and biological activity of novel Magmas inhibitors. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3479-82. doi: 10.1016/j.bmcl.2011.03.050. Epub 2011 Mar 21. PubMed PMID: 21514823.
Venkatesh M, Wang H, Cayer J, Leroux M, Salvail D, Das B, Wrobel JE, Mani S. In vivo and in vitro characterization of a first-in-class novel azole analog that targets pregnane X receptor activation. Mol Pharmacol. 2011 Jul;80(1):124-35. doi: 10.1124/mol.111.071787. Epub 2011 Apr 4. PubMed PMID: 21464197; PubMed Central PMCID: PMC3127530.
Das BC, Zhao X, Tang XY, Yang F. Design, synthesis and biological study of pinacolyl boronate-substituted stilbenes as novel lipogenic inhibitors. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5638-41. doi: 10.1016/j.bmcl.2011.05.124. Epub 2011 Jun 28. PubMed PMID: 21798740; PubMed Central PMCID: PMC3440444.
Smith ME, Das BC, Kalpana GV. In vitro activities of novel 4-HPR derivatives on a panel of rhabdoid and other tumor cell lines. Cancer Cell Int. 2011 Sep 27;11:34. doi: 10.1186/1475-2867-11-34. PubMed PMID: 21951911; PubMed Central PMCID: PMC3204277.
Zhong Y, Wu Y, Liu R, Li Z, Chen Y, Evans T, Chuang P, Das B, He JC. Novel retinoic acid receptor alpha agonists for treatment of kidney disease. PLoS One. 2011;6(11):e27945. doi: 10.1371/journal.pone.0027945. Epub 2011 Nov 18. PubMed PMID: 22125642; PubMed Central PMCID: PMC3220717.
Das BC, Tang XY, Evans T. Design and synthesis of boron containing potential pan-RAR inverse agonists. Tetrahedron Lett. 2012 Mar 14;53(11):1316-1318. doi: 10.1016/j.tetlet.2011.12.118. Epub 2012 Jan 3. PubMed PMID: 23180890; PubMed Central PMCID: PMC3505081.
Das BC, Tang XY, Rogler P, Evans T. Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs. Tetrahedron Lett. 2012 Aug 1;53(31):3947-3950. doi: 10.1016/j.tetlet.2012.02.110. PubMed PMID: 24039307; PubMed Central PMCID: PMC3771381.
Narayanan A, Kehn-Hall K, Senina S, Lundberg L, Van Duyne R, Guendel I, Das R, Baer A, Bethel L, Turell M, Hartman AL, Das B, Bailey C, Kashanchi F. Curcumin inhibits Rift Valley fever virus replication in human cells. J Biol Chem. 2012 Sep 28;287(40):33198-214. doi: 10.1074/jbc.M112.356535. Epub 2012 Jul 30. PubMed PMID: 22847000; PubMed Central PMCID: PMC3460426.
Das BC, Thapa P, Karki R, Schinke C, Das S, Kambhampati S, Banerjee SK, Van Veldhuizen P, Verma A, Weiss LM, Evans T. Boron chemicals in diagnosis and therapeutics. Future Med Chem. 2013 Apr;5(6):653-76. doi: 10.4155/fmc.13.38. Review. PubMed PMID: 23617429; PubMed Central PMCID: PMC3703777.
Anguiano J, Garner TP, Mahalingam M, Das BC, Gavathiotis E, Cuervo AM. Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives. Nat Chem Biol. 2013 Jun;9(6):374-82. doi: 10.1038/nchembio.1230. Epub 2013 Apr 14. PubMed PMID: 23584676; PubMed Central PMCID: PMC3661710.
Das BC, McCormick L, Thapa P, Karki R, Evans T. Use of zebrafish in chemical biology and drug discovery. Future Med Chem. 2013 Nov;5(17):2103-16. doi: 10.4155/fmc.13.170. Review. PubMed PMID: 24215349.
Das BC, Thapa P, Karki R, Das S, Mahapatra S, Liu TC, Torregroza I, Wallace DP, Kambhampati S, Van Veldhuizen P, Verma A, Ray SK, Evans T. Retinoic acid signaling pathways in development and diseases. Bioorg Med Chem. 2014 Jan 15;22(2):673-83. doi: 10.1016/j.bmc.2013.11.025. Epub 2013 Nov 22. Review. PubMed PMID: 24393720; PubMed Central PMCID: PMC4447240.
Soriano-Ursúa MA, Das BC, Trujillo-Ferrara JG. Boron-containing compounds: chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy. Expert Opin Ther Pat. 2014 May;24(5):485-500. doi: 10.1517/13543776.2014.881472. Epub 2014 Jan 24. Review. PubMed PMID: 24456081.
Zhao X, Xiaoli, Zong H, Abdulla A, Yang ES, Wang Q, Ji JY, Pessin JE, Das BC, Yang F. Inhibition of SREBP transcriptional activity by a boron-containing compound improves lipid homeostasis in diet-induced obesity. Diabetes. 2014 Jul;63(7):2464-73. doi: 10.2337/db13-0835. Epub 2014 Mar 7. PubMed PMID: 24608444; PubMed Central PMCID: PMC4066337.
Brun PJ, Grijalva A, Rausch R, Watson E, Yuen JJ, Das BC, Shudo K, Kagechika H, Leibel RL, Blaner WS. Retinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and β-cell mass. FASEB J. 2015 Feb;29(2):671-83. doi: 10.1096/fj.14-256743. Epub 2014 Nov 11. PubMed PMID: 25389133; PubMed Central PMCID: PMC4314234.
Mai Y, Yu JJ, Bartholdy B, Xu-Monette ZY, Knapp EE, Yuan F, Chen H, Ding BB, Yao Z, Das B, Zou Y, Young KH, Parekh S, Ye BH. An oxidative stress-based mechanism of doxorubicin cytotoxicity suggests new therapeutic strategies in ABC-DLBCL. Blood. 2016 Dec 15;128(24):2797-2807. doi: 10.1182/blood-2016-03-705814. Epub 2016 Oct 13. PubMed PMID: 27737889; PubMed Central PMCID: PMC5159702.
Solingapuram Sai KK, Das BC, Sattiraju A, Almaguel FG, Craft S, Mintz A. Radiolabeling and initial biological evaluation of [(18)F]KBM-1 for imaging RAR-α receptors in neuroblastoma. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1425-1427. doi: 10.1016/j.bmcl.2017.01.093. Epub 2017 Feb 1. PubMed PMID: 28216044; PubMed Central PMCID: PMC5724519.
Liu R, Das B, Xiao W, Li Z, Li H, Lee K, He JC. A Novel Inhibitor of Homeodomain Interacting Protein Kinase 2 Mitigates Kidney Fibrosis through Inhibition of the TGF-β1/Smad3 Pathway. J Am Soc Nephrol. 2017 Jul;28(7):2133-2143. doi: 10.1681/ASN.2016080841. Epub 2017 Feb 20. PubMed PMID: 28220029; PubMed Central PMCID: PMC5491283.
Raghava N, Das BC, Ray SK. Neuroprotective effects of estrogen in CNS injuries: insights from animal models. Neurosci Neuroecon. 2017;6:15-29. doi: 10.2147/NAN.S105134. Epub 2017 Jul 4. PubMed PMID: 28845391; PubMed Central PMCID: PMC5567743.
Pérez-Rodríguez M, García-Mendoza E, Farfán-García ED, Das BC, Ciprés-Flores FJ, Trujillo-Ferrara JG, Tamay-Cach F, Soriano-Ursúa MA. Not all boronic acids with a five-membered cycle induce tremor, neuronal damage and decreased dopamine. Neurotoxicology. 2017 Sep;62:92-99. doi: 10.1016/j.neuro.2017.06.004. Epub 2017 Jun 6. PubMed PMID: 28595910.
Mendelson K, Pandey S, Hisano Y, Carellini F, Das BC, Hla T, Evans T. The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis. Elife. 2017 Sep 28;6. doi: 10.7554/eLife.21992. PubMed PMID: 28956531; PubMed Central PMCID: PMC5650468.
Akgul A, Al-Janabi N, Das B, Lawrence M, Karsi A. Small molecules targeting LapB protein prevent Listeria attachment to catfish muscle. PLoS One. 2017;12(12):e0189809. doi: 10.1371/journal.pone.0189809. eCollection 2017. PubMed PMID: 29253892; PubMed Central PMCID: PMC5734760.
Hong Q, Zhang L, Das B, Li Z, Liu B, Cai G, Chen X, Chuang PY, He JC, Lee K. Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury. Kidney Int. 2018 Jun;93(6):1330-1343. doi: 10.1016/j.kint.2017.12.008. Epub 2018 Feb 22. PubMed PMID: 29477240; PubMed Central PMCID: PMC5967974.
Wei C, Banu K, Garzon F, Basgen JM, Philippe N, Yi Z, Liu R, Choudhuri J, Fribourg M, Liu T, Cumpelik A, Wong J, Khan M, Das B, Keung K, Salem F, Campbell KN, Kaufman L, Cravedi P, Zhang W, O'Connell PJ, He JC, Murphy B, Menon MC. SHROOM3-FYN Interaction Regulates Nephrin Phosphorylation and Affects Albuminuria in Allografts. J Am Soc Nephrol. 2018 Nov;29(11):2641-2657. doi: 10.1681/ASN.2018060573. Epub 2018 Oct 19. PubMed PMID: 30341149; PubMed Central PMCID: PMC6218856.
Taylor MA, Das BC, Ray SK. Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma. Apoptosis. 2018 Dec;23(11-12):563-575. doi: 10.1007/s10495-018-1480-9. Review. PubMed PMID: 30171377; PubMed Central PMCID: PMC6193815.
Di K, Lomeli N, Bota DA, Das BC. Magmas inhibition as a potential treatment strategy in malignant glioma. J Neurooncol. 2019 Jan;141(2):267-276. doi: 10.1007/s11060-018-03040-8. Epub 2018 Nov 9. PubMed PMID: 30414099; PubMed Central PMCID: PMC6474352.
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