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Dai T, Pikkula BM, Tunnell JW, Chang DW, Anvari B. Thermal response of human skin epidermis to 595-nm laser irradiation at high incident dosages and long pulse durations in conjunction with cryogen spray cooling: an ex-vivo study. Lasers Surg Med. 2003;33(1):16-24. doi: 10.1002/lsm.10183. PubMed PMID: 12866117.
Dai T, Pikkula BM, Wang LV, Anvari B. Comparison of human skin opto-thermal response to near-infrared and visible laser irradiations: a theoretical investigation. Phys Med Biol. 2004 Nov 7;49(21):4861-77. doi: 10.1088/0031-9155/49/21/002. PubMed PMID: 15584524.
Pikkula BM, Chang DW, Dai T, Anvari B. Epidermal and vascular damage analysis of in vivo human skin in response to 595 nm pulsed laser irradiation. Lasers Surg Med. 2005 Jul;37(1):19-28. doi: 10.1002/lsm.20191. PubMed PMID: 15971245.
Dai T, Diagaradjane P, Yaseen MA, Pikkula BM, Thomsen S, Anvari B. Laser-induced thermal injury to dermal blood vessels: analysis of wavelength (585 nm vs. 595 nm), cryogen spray cooling, and wound healing effects. Lasers Surg Med. 2005 Sep;37(3):210-8. doi: 10.1002/lsm.20217. PubMed PMID: 16175632.
Behroozan DS, Goldberg LH, Glaich AS, Dai T, Friedman PM. Fractional photothermolysis for treatment of poikiloderma of civatte. Dermatol Surg. 2006 Feb;32(2):298-301. doi: 10.1111/j.1524-4725.2006.32061.x. PubMed PMID: 16442059.
Behroozan DS, Goldberg LH, Dai T, Geronemus RG, Friedman PM. Fractional photothermolysis for the treatment of surgical scars: a case report. J Cosmet Laser Ther. 2006 Apr;8(1):35-8. doi: 10.1080/14764170600607251. PubMed PMID: 16581684.
Dai T, Yaseen MA, Diagaradjane P, Chang DW, Anvari B. Comparative study of cryogen spray cooling with R-134a and R-404a: implications for laser treatment of dark human skin. J Biomed Opt. 2006 Jul-Aug;11(4):041116. doi: 10.1117/1.2338001. PubMed PMID: 16965144.
Glaich AS, Goldberg LH, Dai T, Friedman PM. Fractional photothermolysis for the treatment of telangiectatic matting: a case report. J Cosmet Laser Ther. 2007 Jun;9(2):101-3. doi: 10.1080/14764170701218586. PubMed PMID: 17558760.
Castano AP, Dai T, Yaroslavsky I, Cohen R, Apruzzese WA, Smotrich MH, Hamblin MR. Low-level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time. Lasers Surg Med. 2007 Jul;39(6):543-50. doi: 10.1002/lsm.20516. PubMed PMID: 17659584; PubMed Central PMCID: PMC2935792.
Glaich AS, Goldberg LH, Dai T, Kunishige JH, Friedman PM. Fractional resurfacing: a new therapeutic modality for Becker's nevus. Arch Dermatol. 2007 Dec;143(12):1488-90. doi: 10.1001/archderm.143.12.1488. PubMed PMID: 18086996.
Dai T, Tegos GP, Rolz-Cruz G, Cumbie WE, Hamblin MR. Ultraviolet C inactivation of dermatophytes: implications for treatment of onychomycosis. Br J Dermatol. 2008 Jun;158(6):1239-46. doi: 10.1111/j.1365-2133.2008.08549.x. Epub 2008 Apr 10. PubMed PMID: 18410410; PubMed Central PMCID: PMC2808700.
Dai T, Tegos GP, Burkatovskaya M, Castano AP, Hamblin MR. Chitosan acetate bandage as a topical antimicrobial dressing for infected burns. Antimicrob Agents Chemother. 2009 Feb;53(2):393-400. doi: 10.1128/AAC.00760-08. Epub 2008 Nov 17. PubMed PMID: 19015341; PubMed Central PMCID: PMC2630614.
Dai T, Tegos GP, Lu Z, Huang L, Zhiyentayev T, Franklin MJ, Baer DG, Hamblin MR. Photodynamic therapy for Acinetobacter baumannii burn infections in mice. Antimicrob Agents Chemother. 2009 Sep;53(9):3929-34. doi: 10.1128/AAC.00027-09. Epub 2009 Jun 29. PubMed PMID: 19564369; PubMed Central PMCID: PMC2737832.
Dai T, Huang YY, Hamblin MR. Photodynamic therapy for localized infections--state of the art. Photodiagnosis Photodyn Ther. 2009 Sep-Dec;6(3-4):170-88. doi: 10.1016/j.pdpdt.2009.10.008. Review. PubMed PMID: 19932449; PubMed Central PMCID: PMC2811240.
Dai T, Tegos GP, Zhiyentayev T, Mylonakis E, Hamblin MR. Photodynamic therapy for methicillin-resistant Staphylococcus aureus infection in a mouse skin abrasion model. Lasers Surg Med. 2010 Jan;42(1):38-44. doi: 10.1002/lsm.20887. PubMed PMID: 20077489; PubMed Central PMCID: PMC2820267.
Huang L, Dai T, Hamblin MR. Antimicrobial photodynamic inactivation and photodynamic therapy for infections. Methods Mol Biol. 2010;635:155-73. doi: 10.1007/978-1-60761-697-9_12. PubMed PMID: 20552347; PubMed Central PMCID: PMC2933785.
Hamblin MR, Dai T. Can surgical site infections be treated by photodynamic therapy?. Photodiagnosis Photodyn Ther. 2010 Jun;7(2):134-6. doi: 10.1016/j.pdpdt.2010.04.004. PubMed PMID: 20510311; PubMed Central PMCID: PMC2945525.
Ragàs X, Dai T, Tegos GP, Agut M, Nonell S, Hamblin MR. Photodynamic inactivation of Acinetobacter baumannii using phenothiazinium dyes: in vitro and in vivo studies. Lasers Surg Med. 2010 Jul;42(5):384-90. doi: 10.1002/lsm.20922. PubMed PMID: 20583252; PubMed Central PMCID: PMC2935797.
Katz TM, Glaich AS, Goldberg LH, Firoz BF, Dai T, Friedman PM. Treatment of melasma using fractional photothermolysis: a report of eight cases with long-term follow-up. Dermatol Surg. 2010 Aug;36(8):1273-80. doi: 10.1111/j.1524-4725.2010.01621.x. PubMed PMID: 20666816.
Ragàs X, Sánchez-García D, Ruiz-González R, Dai T, Agut M, Hamblin MR, Nonell S. Cationic porphycenes as potential photosensitizers for antimicrobial photodynamic therapy. J Med Chem. 2010 Nov 11;53(21):7796-803. doi: 10.1021/jm1009555. PubMed PMID: 20936792; PubMed Central PMCID: PMC2981434.
Lu Z, Dai T, Huang L, Kurup DB, Tegos GP, Jahnke A, Wharton T, Hamblin MR. Photodynamic therapy with a cationic functionalized fullerene rescues mice from fatal wound infections. Nanomedicine (Lond). 2010 Dec;5(10):1525-33. doi: 10.2217/nnm.10.98. PubMed PMID: 21143031; PubMed Central PMCID: PMC3047412.
Sharma SK, Dai T, Kharkwal GB, Huang YY, Huang L, De Arce VJ, Tegos GP, Hamblin MR. Drug discovery of antimicrobial photosensitizers using animal models. Curr Pharm Des. 2011;17(13):1303-19. doi: 10.2174/138161211795703735. Review. PubMed PMID: 21504410; PubMed Central PMCID: PMC3463379.
Dai T, Tegos GP, St Denis TG, Anderson D, Sinofsky E, Hamblin MR. Ultraviolet-C irradiation for prevention of central venous catheter-related infections: an in vitro study. Photochem Photobiol. 2011 Jan-Feb;87(1):250-5. doi: 10.1111/j.1751-1097.2010.00819.x. Epub 2010 Nov 12. PubMed PMID: 21073470; PubMed Central PMCID: PMC3010268.
Dai T, Kharkwal GB, Zhao J, St Denis TG, Wu Q, Xia Y, Huang L, Sharma SK, d'Enfert C, Hamblin MR. Ultraviolet-C light for treatment of Candida albicans burn infection in mice. Photochem Photobiol. 2011 Mar-Apr;87(2):342-9. doi: 10.1111/j.1751-1097.2011.00886.x. Epub 2011 Feb 10. PubMed PMID: 21208209; PubMed Central PMCID: PMC3048910.
St Denis TG, Huang L, Dai T, Hamblin MR. Analysis of the bacterial heat shock response to photodynamic therapy-mediated oxidative stress. Photochem Photobiol. 2011 May-Jun;87(3):707-13. doi: 10.1111/j.1751-1097.2011.00902.x. Epub 2011 Feb 22. PubMed PMID: 21261628; PubMed Central PMCID: PMC3082629.
Dai T, Tanaka M, Huang YY, Hamblin MR. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert Rev Anti Infect Ther. 2011 Jul;9(7):857-79. doi: 10.1586/eri.11.59. Review. PubMed PMID: 21810057; PubMed Central PMCID: PMC3188448.
Huang L, Dai T, Xuan Y, Tegos GP, Hamblin MR. Synergistic combination of chitosan acetate with nanoparticle silver as a topical antimicrobial: efficacy against bacterial burn infections. Antimicrob Agents Chemother. 2011 Jul;55(7):3432-8. doi: 10.1128/AAC.01803-10. Epub 2011 Apr 18. PubMed PMID: 21502618; PubMed Central PMCID: PMC3122390.
Wainwright M, Dai T, Hamblin MR. Antimicrobial photodynamic therapy in the colon: delivering a light punch to the guts?. Photochem Photobiol. 2011 Jul-Aug;87(4):754-6. doi: 10.1111/j.1751-1097.2011.00925.x. Epub 2011 Apr 12. PubMed PMID: 21418077; PubMed Central PMCID: PMC3132272.
Dai T, Kharkwal GB, Tanaka M, Huang YY, Bil de Arce VJ, Hamblin MR. Animal models of external traumatic wound infections. Virulence. 2011 Jul-Aug;2(4):296-315. doi: 10.4161/viru.2.4.16840. Epub 2011 Jul 1. Review. PubMed PMID: 21701256; PubMed Central PMCID: PMC3173676.
Kharkwal GB, Sharma SK, Huang YY, Dai T, Hamblin MR. Photodynamic therapy for infections: clinical applications. Lasers Surg Med. 2011 Sep;43(7):755-67. doi: 10.1002/lsm.21080. Review. PubMed PMID: 22057503; PubMed Central PMCID: PMC3449167.
Ando T, Xuan W, Xu T, Dai T, Sharma SK, Kharkwal GB, Huang YY, Wu Q, Whalen MJ, Sato S, Obara M, Hamblin MR. Comparison of therapeutic effects between pulsed and continuous wave 810-nm wavelength laser irradiation for traumatic brain injury in mice. PLoS One. 2011;6(10):e26212. doi: 10.1371/journal.pone.0026212. Epub 2011 Oct 18. PubMed PMID: 22028832; PubMed Central PMCID: PMC3196530.
St Denis TG, Dai T, Izikson L, Astrakas C, Anderson RR, Hamblin MR, Tegos GP. All you need is light: antimicrobial photoinactivation as an evolving and emerging discovery strategy against infectious disease. Virulence. 2011 Nov-Dec;2(6):509-20. doi: 10.4161/viru.2.6.17889. Epub 2011 Nov 1. Review. PubMed PMID: 21971183; PubMed Central PMCID: PMC3260545.
Mroz P, Xia Y, Asanuma D, Konopko A, Zhiyentayev T, Huang YY, Sharma SK, Dai T, Khan UJ, Wharton T, Hamblin MR. Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma. Nanomedicine. 2011 Dec;7(6):965-74. doi: 10.1016/j.nano.2011.04.007. Epub 2011 May 19. PubMed PMID: 21645643; PubMed Central PMCID: PMC3183379.
Dai T, Bil de Arce VJ, Tegos GP, Hamblin MR. Blue dye and red light, a dynamic combination for prophylaxis and treatment of cutaneous Candida albicans infections in mice. Antimicrob Agents Chemother. 2011 Dec;55(12):5710-7. doi: 10.1128/AAC.05404-11. Epub 2011 Sep 19. PubMed PMID: 21930868; PubMed Central PMCID: PMC3232820.
Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hirayama T, Dai T, Huang L, Hamblin MR, Morimoto Y. Optimal photosensitizers for photodynamic therapy of infections should kill bacteria but spare neutrophils. Photochem Photobiol. 2012 Jan-Feb;88(1):227-32. doi: 10.1111/j.1751-1097.2011.01005.x. Epub 2011 Oct 31. PubMed PMID: 21950417; PubMed Central PMCID: PMC3253242.
Dai T, Vrahas MS, Murray CK, Hamblin MR. Ultraviolet C irradiation: an alternative antimicrobial approach to localized infections?. Expert Rev Anti Infect Ther. 2012 Feb;10(2):185-95. doi: 10.1586/eri.11.166. Review. PubMed PMID: 22339192; PubMed Central PMCID: PMC3292282.
Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng. 2012 Feb;40(2):516-33. doi: 10.1007/s10439-011-0454-7. Epub 2011 Nov 2. Review. PubMed PMID: 22045511; PubMed Central PMCID: PMC3288797.
Dai T, Fuchs BB, Coleman JJ, Prates RA, Astrakas C, St Denis TG, Ribeiro MS, Mylonakis E, Hamblin MR, Tegos GP. Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform. Front Microbiol. 2012;3:120. doi: 10.3389/fmicb.2012.00120. eCollection 2012. PubMed PMID: 22514547; PubMed Central PMCID: PMC3322354.
Vera DM, Haynes MH, Ball AR, Dai T, Astrakas C, Kelso MJ, Hamblin MR, Tegos GP. Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes. Photochem Photobiol. 2012 May-Jun;88(3):499-511. doi: 10.1111/j.1751-1097.2012.01087.x. Epub 2012 Feb 13. Review. PubMed PMID: 22242675; PubMed Central PMCID: PMC3345078.
Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Nemoto K, Shinomiya N, Seki S, Hamblin MR. Photodynamic therapy can induce a protective innate immune response against murine bacterial arthritis via neutrophil accumulation. PLoS One. 2012;7(6):e39823. doi: 10.1371/journal.pone.0039823. Epub 2012 Jun 26. PubMed PMID: 22761911; PubMed Central PMCID: PMC3383702.
Dai T, Garcia B, Murray CK, Vrahas MS, Hamblin MR. UVC light prophylaxis for cutaneous wound infections in mice. Antimicrob Agents Chemother. 2012 Jul;56(7):3841-8. doi: 10.1128/AAC.00161-12. Epub 2012 May 7. PubMed PMID: 22564833; PubMed Central PMCID: PMC3393382.
Dai T, Gupta A, Murray CK, Vrahas MS, Tegos GP, Hamblin MR. Blue light for infectious diseases: Propionibacterium acnes, Helicobacter pylori, and beyond?. Drug Resist Updat. 2012 Aug;15(4):223-36. doi: 10.1016/j.drup.2012.07.001. Epub 2012 Jul 28. Review. PubMed PMID: 22846406; PubMed Central PMCID: PMC3438385.
Dai T, Murray CK, Vrahas MS, Baer DG, Tegos GP, Hamblin MR. Ultraviolet C light for Acinetobacter baumannii wound infections in mice: potential use for battlefield wound decontamination?. J Trauma Acute Care Surg. 2012 Sep;73(3):661-7. doi: 10.1097/TA.0b013e31825c149c. PubMed PMID: 22929495; PubMed Central PMCID: PMC3463377.
Sharma SK, Mroz P, Dai T, Huang YY, St Denis TG, Hamblin MR. Photodynamic Therapy for Cancer and for Infections: What Is the Difference?. Isr J Chem. 2012 Sep;52(8-9):691-705. doi: 10.1002/ijch.201100062. PubMed PMID: 23248387; PubMed Central PMCID: PMC3522418.
St Denis TG, Dai T, Hamblin MR. Killing bacterial spores with blue light: when innate resistance meets the power of light. Photochem Photobiol. 2013 Jan-Feb;89(1):2-4. doi: 10.1111/j.1751-1097.2012.01233.x. Epub 2012 Oct 12. PubMed PMID: 22946878; PubMed Central PMCID: PMC3556167.
Xuan W, Vatansever F, Huang L, Wu Q, Xuan Y, Dai T, Ando T, Xu T, Huang YY, Hamblin MR. Transcranial low-level laser therapy improves neurological performance in traumatic brain injury in mice: effect of treatment repetition regimen. PLoS One. 2013;8(1):e53454. doi: 10.1371/journal.pone.0053454. Epub 2013 Jan 7. PubMed PMID: 23308226; PubMed Central PMCID: PMC3538543.
Baxter RM, Dai T, Kimball J, Wang E, Hamblin MR, Wiesmann WP, McCarthy SJ, Baker SM. Chitosan dressing promotes healing in third degree burns in mice: gene expression analysis shows biphasic effects for rapid tissue regeneration and decreased fibrotic signaling. J Biomed Mater Res A. 2013 Feb;101(2):340-8. doi: 10.1002/jbm.a.34328. Epub 2012 Jul 30. PubMed PMID: 22847951; PubMed Central PMCID: PMC3488117.
Dai T, Gupta A, Huang YY, Yin R, Murray CK, Vrahas MS, Sherwood ME, Tegos GP, Hamblin MR. Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action. Antimicrob Agents Chemother. 2013 Mar;57(3):1238-45. doi: 10.1128/AAC.01652-12. Epub 2012 Dec 21. PubMed PMID: 23262998; PubMed Central PMCID: PMC3591931.
Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hamblin MR. Linezolid and vancomycin decrease the therapeutic effect of methylene blue-photodynamic therapy in a mouse model of MRSA bacterial arthritis. Photochem Photobiol. 2013 May-Jun;89(3):679-82. doi: 10.1111/php.12040. Epub 2013 Feb 19. PubMed PMID: 23311407; PubMed Central PMCID: PMC3636181.
Sperandio FF, Sharma SK, Wang M, Jeon S, Huang YY, Dai T, Nayka S, de Sousa SC, Chiang LY, Hamblin MR. Photoinduced electron-transfer mechanisms for radical-enhanced photodynamic therapy mediated by water-soluble decacationic C₇₀ and C₈₄O₂ Fullerene Derivatives. Nanomedicine. 2013 May;9(4):570-9. doi: 10.1016/j.nano.2012.09.005. Epub 2012 Oct 29. PubMed PMID: 23117043; PubMed Central PMCID: PMC3582824.
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