My Bibliography

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Gasonoo M, Guin S, Teixeira JE, Oboh E, Gokanapalle A, Miller P, Oliva J, Sverdrup FM, Huston CD, Meyers MJ. Discovery of an Orally Efficacious Pyrazolo[3,4-d]pyrimidine Benzoxaborole as a Potent Inhibitor of Cryptosporidium. J Med Chem. 2025 Jan 9;68(1):832-849. doi: 10.1021/acs.jmedchem.4c02805. Epub 2024 Dec 23. PubMed PMID: 39714730.

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Guin S, Montoya MC, Wang X, Zarnowski R, Andes DR, Meyers MJ, Williams NS, Krysan DJ. Analogs of the anti-malaria drug mefloquine have broad-spectrum antifungal activity and are efficacious in a model of disseminated Candida auris infection. Antimicrob Agents Chemother. 2024 Nov 6;68(11):e0130124. doi: 10.1128/aac.01301-24. Epub 2024 Oct 4. PubMed PMID: 39365066; PubMed Central PMCID: PMC11539235.

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Ajiboye J, Teixeira JE, Gasonoo M, Mattice EB, Korwin-Mihavics B, Miller P, Cameron AC, Stebbins E, Campbell SD, Griggs DW, Spangenberg T, Meyers MJ, Huston CD. Identification of potent and orally efficacious phosphodiesterase inhibitors in Cryptosporidium parvum-infected immunocompromised male mice. Nat Commun. 2024 Sep 27;15(1):8272. doi: 10.1038/s41467-024-52658-y. PubMed PMID: 39333545; PubMed Central PMCID: PMC11436873.

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Tu T, Wettengel J, Xia Y, Testoni B, Littlejohn M, Le Bert N, Ebert G, Verrier ER, Tavis JE, Cohen C. Major open questions in the hepatitis B and D field - Proceedings of the inaugural International emerging hepatitis B and hepatitis D researchers workshop. Virology. 2024 Jul;595:110089. doi: 10.1016/j.virol.2024.110089. Epub 2024 Apr 16. PubMed PMID: 38640789; PubMed Central PMCID: PMC11517827.

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Moianos D, Makri M, Prifti GM, Chiotellis A, Pappas A, Woodson ME, Tajwar R, Tavis JE, Zoidis G. N-Hydroxypiridinedione: A Privileged Heterocycle for Targeting the HBV RNase H. Molecules. 2024 Jun 20;29(12). doi: 10.3390/molecules29122942. PubMed PMID: 38931006; PubMed Central PMCID: PMC11206691.

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Guin S, Alden KM, Krysan DJ, Meyers MJ. Synthesis and Antifungal Activity of Stereoisomers of Mefloquine Analogs. ACS Med Chem Lett. 2024 Jun 13;15(6):822-827. doi: 10.1021/acsmedchemlett.4c00031. eCollection 2024 Jun 13. PubMed PMID: 38894917; PubMed Central PMCID: PMC11181485.

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Cancilla D, Rettig MP, Karpova D, Thakellapalli H, Singh M, Meyers MJ, Ruminski PG, Christ S, Chendamarai E, Gao F, Gehrs L, Ritchey JK, Prinsen M, DiPersio JF. Targeting CXCR4, VLA-4, and CXCR2 for hematopoietic stem cell mobilization. Blood Adv. 2024 Mar 26;8(6):1379-1383. doi: 10.1182/bloodadvances.2023011653. PubMed PMID: 38190608; PubMed Central PMCID: PMC10945136.

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Giannakopoulou E, Pardali V, Edwards TC, Woodson M, Tajwar R, Tavis JE, Zoidis G. Identification and assessment of the 1,6-dihydroxy-pyridin-2-one moiety as privileged scaffold for HBV ribonuclease H inhibition. Antiviral Res. 2024 Mar;223:105833. doi: 10.1016/j.antiviral.2024.105833. Epub 2024 Feb 5. PubMed PMID: 38325606; PubMed Central PMCID: PMC11533872.

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Keroack CD, Elsworth B, Tennessen JA, Paul AS, Hua R, Ramirez-Ramirez L, Ye S, Moreira CK, Meyers MJ, Zarringhalam K, Duraisingh MT. Comparative chemical genomics in Babesia species identifies the alkaline phosphatase PhoD as a determinant of antiparasitic resistance. Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2312987121. doi: 10.1073/pnas.2312987121. Epub 2024 Feb 20. PubMed PMID: 38377214; PubMed Central PMCID: PMC10907312.

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Li Q, Tavis JE. In Vitro Enzymatic and Cell Culture-Based Assays for Measuring Activity of HBV Ribonuclease H Inhibitors. Methods Mol Biol. 2024;2837:257-270. doi: 10.1007/978-1-0716-4027-2_22. PubMed PMID: 39044091; PubMed Central PMCID: PMC11514518.

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Woodson ME, Mottaleb MA, Murelli RP, Tavis JE. In vitro evaluation of tropolone absorption, metabolism, and clearance. Antiviral Res. 2023 Dec;220:105762. doi: 10.1016/j.antiviral.2023.105762. Epub 2023 Nov 22. PubMed PMID: 37996012; PubMed Central PMCID: PMC10843707.

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Miron-Ocampo A, Beattie SR, Guin S, Conway T, Meyers MJ, Moye-Rowley WS, Krysan DJ. CWHM-974 is a fluphenazine derivative with improved antifungal activity against Candida albicans due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms. Antimicrob Agents Chemother. 2023 Oct 18;67(10):e0056723. doi: 10.1128/aac.00567-23. Epub 2023 Sep 13. PubMed PMID: 37702508; PubMed Central PMCID: PMC10583685.

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Vanneste M, Venzke A, Guin S, Fuller AJ, Jezewski AJ, Beattie SR, Krysan DJ, Meyers MJ, Henry MD. The anti-cancer efficacy of a novel phenothiazine derivative is independent of dopamine and serotonin receptor inhibition. Front Oncol. 2023;13:1295185. doi: 10.3389/fonc.2023.1295185. eCollection 2023. PubMed PMID: 37909019; PubMed Central PMCID: PMC10613967.

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Gilbert IH, Vinayak S, Striepen B, Manjunatha UH, Khalil IA, Van Voorhis WC. Safe and effective treatments are needed for cryptosporidiosis, a truly neglected tropical disease. BMJ Glob Health. 2023 Aug;8(8). doi: 10.1136/bmjgh-2023-012540. PubMed PMID: 37541693; PubMed Central PMCID: PMC10407372.

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Wang X, Edwards RL, Ball HS, Heidel KM, Brothers RC, Johnson C, Haymond A, Girma M, Dailey A, Roma JS, Boshoff HI, Osbourn DM, Meyers MJ, Couch RD, Odom John AR, Dowd CS. MEPicides: α,β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase. ACS Infect Dis. 2023 Jul 14;9(7):1387-1395. doi: 10.1021/acsinfecdis.3c00132. Epub 2023 Jun 13. PubMed PMID: 37310810; PubMed Central PMCID: PMC10880585.

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Schubert TJ, Oboh E, Peek H, Philo E, Teixeira JE, Stebbins EE, Miller P, Oliva J, Sverdrup FM, Griggs DW, Huston CD, Meyers MJ. Structure-Activity Relationship Studies of the Aryl Acetamide Triazolopyridazines against Cryptosporidium Reveals Remarkable Role of Fluorine. J Med Chem. 2023 Jun 22;66(12):7834-7848. doi: 10.1021/acs.jmedchem.3c00110. Epub 2023 Jun 2. PubMed PMID: 37267631; PubMed Central PMCID: PMC11103792.

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Keroack CD, Elsworth B, Tennessen JA, Paul AS, Hua R, Ramirez-Ramirez L, Ye S, Moreira CM, Meyers MJ, Zarringhalam K, Duraisingh MT. Comparative chemical genomics in Babesia species identifies the alkaline phosphatase phoD as a novel determinant of resistance. bioRxiv. 2023 Jun 13;. doi: 10.1101/2023.06.13.544849. PubMed PMID: 37398106; PubMed Central PMCID: PMC10312741.

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Oboh E, Teixeira JE, Schubert TJ, Maribona AS, Denman BN, Patel R, Huston CD, Meyers MJ. Structure-Activity relationships of replacements for the triazolopyridazine of Anti-Cryptosporidium lead SLU-2633. Bioorg Med Chem. 2023 May 15;86:117295. doi: 10.1016/j.bmc.2023.117295. Epub 2023 Apr 28. PubMed PMID: 37148788; PubMed Central PMCID: PMC10201403.

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Wang S, Ren Y, Li Q, Wang Y, Jiang X, Xu S, Zhang X, Zhao S, Bradley DP, Woodson ME, Zhao F, Wu S, Li Y, Tian Y, Liu X, Tavis JE, Zhan P. Design, synthesis, and biological evaluation of novel sulfamoylbenzamide derivatives as HBV capsid assembly modulators. Bioorg Chem. 2022 Dec;129:106192. doi: 10.1016/j.bioorg.2022.106192. Epub 2022 Oct 13. PubMed PMID: 36265355; PubMed Central PMCID: PMC10591450.

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Tajwar R, Bradley DP, Ponzar NL, Tavis JE. Predicted structure of the hepatitis B virus polymerase reveals an ancient conserved protein fold. Protein Sci. 2022 Oct;31(10):e4421. doi: 10.1002/pro.4421. PubMed PMID: 36173165; PubMed Central PMCID: PMC9601786.

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Zangi M, Donald KA, Casals AG, Franson AD, Yu AJ, Marker EM, Woodson ME, Campbell SD, Mottaleb MA, Narayana Hajay Kumar TV, Reddy MS, Raghava Reddy LV, Sadhukhan SK, Griggs DW, Morrison LA, Meyers MJ. Synthetic derivatives of the antifungal drug ciclopirox are active against herpes simplex virus 2. Eur J Med Chem. 2022 Aug 5;238:114443. doi: 10.1016/j.ejmech.2022.114443. Epub 2022 May 14. PubMed PMID: 35635945; PubMed Central PMCID: PMC11103786.

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Donlin MJ, Meyers MJ. Repurposing and optimization of drugs for discovery of novel antifungals. Drug Discov Today. 2022 Jul;27(7):2008-2014. doi: 10.1016/j.drudis.2022.04.021. Epub 2022 Apr 27. Review. PubMed PMID: 35489676; PubMed Central PMCID: PMC11182377.

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Kirby SA, Dowd CS. Phosphoryl Prodrugs: Characteristics to Improve Drug Development. Med Chem Res. 2022 Feb;31(2):207-216. doi: 10.1007/s00044-021-02766-x. Epub 2021 Jul 23. PubMed PMID: 35492863; PubMed Central PMCID: PMC9053384.

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Miller JJ, Shah IT, Hatten J, Barekatain Y, Mueller EA, Moustafa AM, Edwards RL, Dowd CS, Hoops GC, Johnson RJ, Planet P, Muller FL, Jez J, Odom John AR. Correction: Structure-guided microbial targeting of antistaphylococcal prodrugs. Elife. 2021 Nov 25;10. doi: 10.7554/eLife.75743. PubMed PMID: 34821554; PubMed Central PMCID: PMC8616559.

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Chauhan R, Li Q, Woodson ME, Gasonoo M, Meyers MJ, Tavis JE. Efficient Inhibition of Hepatitis B Virus (HBV) Replication and cccDNA Formation by HBV Ribonuclease H Inhibitors during Infection. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0146021. doi: 10.1128/AAC.01460-21. Epub 2021 Sep 13. PubMed PMID: 34516242; PubMed Central PMCID: PMC8597750.

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Girma MB, Ball HS, Wang X, Brothers RC, Jackson ER, Meyers MJ, Dowd CS, Couch RD. Mechanism of Action of N-Acyl and N-Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria. ACS Omega. 2021 Oct 26;6(42):27630-27639. doi: 10.1021/acsomega.1c01711. eCollection 2021 Oct 26. PubMed PMID: 34722963; PubMed Central PMCID: PMC8552233.

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Oboh E, Schubert TJ, Teixeira JE, Stebbins EE, Miller P, Philo E, Thakellapalli H, Campbell SD, Griggs DW, Huston CD, Meyers MJ. Optimization of the Urea Linker of Triazolopyridazine MMV665917 Results in a New Anticryptosporidial Lead with Improved Potency and Predicted hERG Safety Margin. J Med Chem. 2021 Aug 12;64(15):11729-11745. doi: 10.1021/acs.jmedchem.1c01136. Epub 2021 Aug 3. PubMed PMID: 34342443; PubMed Central PMCID: PMC8792998.

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Miller JJ, Shah IT, Hatten J, Barekatain Y, Mueller EA, Moustafa AM, Edwards RL, Dowd CS, Hoops GC, Johnson RJ, Planet PJ, Muller FL, Jez JM, Odom John AR. Structure-guided microbial targeting of antistaphylococcal prodrugs. Elife. 2021 Jul 19;10. doi: 10.7554/eLife.66657. PubMed PMID: 34279224; PubMed Central PMCID: PMC8318587.

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Huston CD. The Clofazimine for Treatment of Cryptosporidiosis in HIV-Infected Adults (CRYPTOFAZ) and Lessons Learned for Anticryptosporidial Drug Development. Clin Infect Dis. 2021 Jul 15;73(2):192-194. doi: 10.1093/cid/ciaa425. PubMed PMID: 32277815; PubMed Central PMCID: PMC8427724.

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Hasan MM, Stebbins EE, Choy RKM, Gillespie JR, de Hostos EL, Miller P, Mushtaq A, Ranade RM, Teixeira JE, Verlinde CLMJ, Sateriale A, Zhang Z, Osbourn DM, Griggs DW, Fan E, Buckner FS, Huston CD. Spontaneous Selection of Cryptosporidium Drug Resistance in a Calf Model of Infection. Antimicrob Agents Chemother. 2021 May 18;65(6). doi: 10.1128/AAC.00023-21. Print 2021 May 18. PubMed PMID: 33753338; PubMed Central PMCID: PMC8316126.

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Prifti GM, Moianos D, Giannakopoulou E, Pardali V, Tavis JE, Zoidis G. Recent Advances in Hepatitis B Treatment. Pharmaceuticals (Basel). 2021 May 1;14(5). doi: 10.3390/ph14050417. Review. PubMed PMID: 34062711; PubMed Central PMCID: PMC8147224.

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Lin J, Zangi M, Kumar TVNH, Shakar Reddy M, Reddy LVR, Sadhukhan SK, Bradley DP, Moreira-Walsh B, Edwards TC, O'Dea AT, Tavis JE, Meyers MJ, Donlin MJ. Synthetic Derivatives of Ciclopirox are Effective Inhibitors of Cryptococcus neoformans. ACS Omega. 2021 Mar 30;6(12):8477-8487. doi: 10.1021/acsomega.1c00273. eCollection 2021 Mar 30. PubMed PMID: 33817509; PubMed Central PMCID: PMC8015083.

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Mikati MO, Miller JJ, Osbourn DM, Barekatain Y, Ghebremichael N, Shah IT, Burnham CD, Heidel KM, Yan VC, Muller FL, Dowd CS, Edwards RL, Odom John AR. Antimicrobial Prodrug Activation by the Staphylococcal Glyoxalase GloB. ACS Infect Dis. 2020 Nov 13;6(11):3064-3075. doi: 10.1021/acsinfecdis.0c00582. Epub 2020 Oct 29. PubMed PMID: 33118347; PubMed Central PMCID: PMC8543975.

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Choy RKM, Huston CD. Cryptosporidiosis should be designated as a tropical disease by the US Food and Drug Administration. PLoS Negl Trop Dis. 2020 Jul;14(7):e0008252. doi: 10.1371/journal.pntd.0008252. eCollection 2020 Jul. PubMed PMID: 32614819; PubMed Central PMCID: PMC7332027.

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Edwards RL, Heueck I, Lee SG, Shah IT, Miller JJ, Jezewski AJ, Mikati MO, Wang X, Brothers RC, Heidel KM, Osbourn DM, Burnham CD, Alvarez S, Fritz SA, Dowd CS, Jez JM, Odom John AR. Potent, specific MEPicides for treatment of zoonotic staphylococci. PLoS Pathog. 2020 Jun;16(6):e1007806. doi: 10.1371/journal.ppat.1007806. eCollection 2020 Jun. PubMed PMID: 32497104; PubMed Central PMCID: PMC7297381.

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Harrison GA, Mayer Bridwell AE, Singh M, Jayaraman K, Weiss LA, Kinsella RL, Aneke JS, Flentie K, Schene ME, Gaggioli M, Solomon SD, Wildman SA, Meyers MJ, Stallings CL. Identification of 4-Amino-Thieno[2,3-d]Pyrimidines as QcrB Inhibitors in Mycobacterium tuberculosis. mSphere. 2019 Sep 11;4(5). doi: 10.1128/mSphere.00606-19. PubMed PMID: 31511370; PubMed Central PMCID: PMC6739496.

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Oliva J, Galasinski S, Richey A, Campbell AE, Meyers MJ, Modi N, Zhong JW, Tawil R, Tapscott SJ, Sverdrup FM. Clinically Advanced p38 Inhibitors Suppress DUX4 Expression in Cellular and Animal Models of Facioscapulohumeral Muscular Dystrophy. J Pharmacol Exp Ther. 2019 Aug;370(2):219-230. doi: 10.1124/jpet.119.259663. Epub 2019 Jun 12. PubMed PMID: 31189728; PubMed Central PMCID: PMC6652132.

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Heidel KM, Dowd CS. Phosphonate prodrugs: an overview and recent advances. Future Med Chem. 2019 Jul;11(13):1625-1643. doi: 10.4155/fmc-2018-0591. Review. PubMed PMID: 31469328; PubMed Central PMCID: PMC6722485.

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Meyers MJ, Liu J, Liu Z, Ma H, Dai L, Adah D, Zhao S, Li X, Liu X, Lu Y, Huang Y, Tu Z, Chen X, Tortorella MD. 4-Aryl Pyrrolidines as Novel Orally Efficacious Antimalarial Agents. Part 2: 2-Aryl-N-(4-arylpyrrolidin-3-yl)acetamides. ACS Med Chem Lett. 2019 Jun 13;10(6):966-971. doi: 10.1021/acsmedchemlett.9b00123. eCollection 2019 Jun 13. PubMed PMID: 31223456; PubMed Central PMCID: PMC6580545.

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Karpova D, Rettig MP, Ritchey J, Cancilla D, Christ S, Gehrs L, Chendamarai E, Evbuomwan MO, Holt M, Zhang J, Abou-Ezzi G, Celik H, Wiercinska E, Yang W, Gao F, Eissenberg LG, Heier RF, Arnett SD, Meyers MJ, Prinsen MJ, Griggs DW, Trumpp A, Ruminski PG, Morrow DM, Bonig HB, Link DC, DiPersio JF. Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells. J Clin Invest. 2019 May 14;129(7):2745-2759. doi: 10.1172/JCI124738. PubMed PMID: 31085833; PubMed Central PMCID: PMC6597242.

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Tavis JE, Zoidis G, Meyers MJ, Murelli RP. Chemical Approaches to Inhibiting the Hepatitis B Virus Ribonuclease H. ACS Infect Dis. 2019 May 10;5(5):655-658. doi: 10.1021/acsinfecdis.8b00045. Epub 2018 Mar 22. Review. PubMed PMID: 29565562; PubMed Central PMCID: PMC7202671.

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Meyers MJ, Liu J, Xu J, Leng F, Guan J, Liu Z, McNitt SA, Qin L, Dai L, Ma H, Adah D, Zhao S, Li X, Polino AJ, Nasamu AS, Goldberg DE, Liu X, Lu Y, Tu Z, Chen X, Tortorella MD. 4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides. J Med Chem. 2019 Apr 11;62(7):3503-3512. doi: 10.1021/acs.jmedchem.8b01972. Epub 2019 Mar 22. PubMed PMID: 30856324; PubMed Central PMCID: PMC6727846.

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Xu P, Ganaie SS, Wang X, Wang Z, Kleiboeker S, Horton NC, Heier RF, Meyers MJ, Tavis JE, Qiu J. Endonuclease Activity Inhibition of the NS1 Protein of Parvovirus B19 as a Novel Target for Antiviral Drug Development. Antimicrob Agents Chemother. 2019 Mar;63(3). doi: 10.1128/AAC.01879-18. Print 2019 Mar. PubMed PMID: 30530599; PubMed Central PMCID: PMC6395930.

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Schnute ME, Wennerstål M, Alley J, Bengtsson M, Blinn JR, Bolten CW, Braden T, Bonn T, Carlsson B, Caspers N, Chen M, Choi C, Collis LP, Crouse K, Färnegårdh M, Fennell KF, Fish S, Flick AC, Goos-Nilsson A, Gullberg H, Harris PK, Heasley SE, Hegen M, Hromockyj AE, Hu X, Husman B, Janosik T, Jones P, Kaila N, Kallin E, Kauppi B, Kiefer JR, Knafels J, Koehler K, Kruger L, Kurumbail RG, Kyne RE Jr, Li W, Löfstedt J, Long SA, Menard CA, Mente S, Messing D, Meyers MJ, Napierata L, Nöteberg D, Nuhant P, Pelc MJ, Prinsen MJ, Rhönnstad P, Backström-Rydin E, Sandberg J, Sandström M, Shah F, Sjöberg M, Sundell A, Taylor AP, Thorarensen A, Trujillo JI, Trzupek JD, Unwalla R, Vajdos FF, Weinberg RA, Wood DC, Xing L, Zamaratski E, Zapf CW, Zhao Y, Wilhelmsson A, Berstein G. Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist. J Med Chem. 2018 Dec 13;61(23):10415-10439. doi: 10.1021/acs.jmedchem.8b00392. Epub 2018 Sep 9. PubMed PMID: 30130103.

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Cao F, Orth C, Donlin MJ, Adegboyega P, Meyers MJ, Murelli RP, Elagawany M, Elgendy B, Tavis JE. Synthesis and Evaluation of Troponoids as a New Class of Antibiotics. ACS Omega. 2018 Nov 30;3(11):15125-15133. doi: 10.1021/acsomega.8b01754. Epub 2018 Nov 8. PubMed PMID: 30533576; PubMed Central PMCID: PMC6275967.

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Wang X, Edwards RL, Ball H, Johnson C, Haymond A, Girma M, Manikkam M, Brothers RC, McKay KT, Arnett SD, Osbourn DM, Alvarez S, Boshoff HI, Meyers MJ, Couch RD, Odom John AR, Dowd CS. MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria. J Med Chem. 2018 Oct 11;61(19):8847-8858. doi: 10.1021/acs.jmedchem.8b01026. Epub 2018 Sep 24. PubMed PMID: 30192536; PubMed Central PMCID: PMC6300130.

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Montoya MC, DiDone L, Heier RF, Meyers MJ, Krysan DJ. Antifungal Phenothiazines: Optimization, Characterization of Mechanism, and Modulation of Neuroreceptor Activity. ACS Infect Dis. 2018 Apr 13;4(4):499-507. doi: 10.1021/acsinfecdis.7b00157. Epub 2017 Nov 2. PubMed PMID: 29058407; PubMed Central PMCID: PMC8994671.

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Jumani RS, Bessoff K, Love MS, Miller P, Stebbins EE, Teixeira JE, Campbell MA, Meyers MJ, Zambriski JA, Nunez V, Woods AK, McNamara CW, Huston CD. A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box. Antimicrob Agents Chemother. 2018 Apr;62(4). doi: 10.1128/AAC.01505-17. Print 2018 Apr. PubMed PMID: 29339392; PubMed Central PMCID: PMC5913971.

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Stebbins E, Jumani RS, Klopfer C, Barlow J, Miller P, Campbell MA, Meyers MJ, Griggs DW, Huston CD. Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model. PLoS Negl Trop Dis. 2018 Jan;12(1):e0006183. doi: 10.1371/journal.pntd.0006183. eCollection 2018 Jan. PubMed PMID: 29309415; PubMed Central PMCID: PMC5774826.

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Nasamu AS, Glushakova S, Russo I, Vaupel B, Oksman A, Kim AS, Fremont DH, Tolia N, Beck JR, Meyers MJ, Niles JC, Zimmerberg J, Goldberg DE. Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion. Science. 2017 Oct 27;358(6362):518-522. doi: 10.1126/science.aan1478. PubMed PMID: 29074774; PubMed Central PMCID: PMC5928414.