Skip to main page content
Accesskeys
  1. Cooke MS, Finnegan MT, Herbert KE, Lunec J. Cell cycle and dose-dependence of DNA damage and p53 expression following UVA irradiation. Biochem Soc Trans. 1995 Aug;23(3):481S. doi: 10.1042/bst023481s. PubMed PMID: 8566379.
  2. Podmore ID, Cooke MS, Herbert KE, Lunec J. Quantitative determination of cyclobutane thymine dimers in DNA by stable isotope-dilution mass spectrometry. Photochem Photobiol. 1996 Aug;64(2):310-5. doi: 10.1111/j.1751-1097.1996.tb02463.x. PubMed PMID: 8760572.
  3. Cooke MS, Mistry N, Wood C, Herbert KE, Lunec J. Immunogenicity of DNA damaged by reactive oxygen species--implications for anti-DNA antibodies in lupus. Free Radic Biol Med. 1997;22(1-2):151-9. PubMed PMID: 8958139.
  4. Cooke MS, Herbert KE, Butler PC, Lunec J. Further evidence for a possible role of conformation in the immunogenicity and antigenicity of the oxidative DNA lesion, 8-oxo-2'deoxyguanosine. Free Radic Res. 1998 May;28(5):459-69. PubMed PMID: 9702526.
  5. Cooke MS, Evans MD, Podmore ID, Herbert KE, Mistry N, Mistry P, Hickenbotham PT, Hussieni A, Griffiths HR, Lunec J. Novel repair action of vitamin C upon in vivo oxidative DNA damage. FEBS Lett. 1998 Nov 20;439(3):363-7. doi: 10.1016/s0014-5793(98)01403-3. PubMed PMID: 9845354.
  6. Evans MD, Cooke MS, Podmore ID, Zheng Q, Herbert KE, Lunec J. Discrepancies in the measurement of UVC-induced 8-oxo-2'-deoxyguanosine: implications for the analysis of oxidative DNA damage. Biochem Biophys Res Commun. 1999 Jun 7;259(2):374-8. doi: 10.1006/bbrc.1999.0801. PubMed PMID: 10362517.
  7. Ahmad J, Cooke MS, Hussieni A, Evans MD, Patel K, Burd RM, Bleiker TO, Hutchinson PE, Lunec J. Urinary thymine dimers and 8-oxo-2'-deoxyguanosine in psoriasis. FEBS Lett. 1999 Nov 5;460(3):549-53. doi: 10.1016/s0014-5793(99)01402-7. PubMed PMID: 10556533.
  8. Cooke MS, Evans MD, Herbert KE, Lunec J. Urinary 8-oxo-2'-deoxyguanosine--source, significance and supplements. Free Radic Res. 2000 May;32(5):381-97. Review. PubMed PMID: 10766407.
  9. Carty JL, Bevan R, Waller H, Mistry N, Cooke M, Lunec J, Griffiths HR. The effects of vitamin C supplementation on protein oxidation in healthy volunteers. Biochem Biophys Res Commun. 2000 Jul 5;273(2):729-35. doi: 10.1006/bbrc.2000.3014. PubMed PMID: 10873672.
  10. Evans MD, Cooke MS, Akil M, Samanta A, Lunec J. Aberrant processing of oxidative DNA damage in systemic lupus erythematosus. Biochem Biophys Res Commun. 2000 Jul 14;273(3):894-8. doi: 10.1006/bbrc.2000.3078. PubMed PMID: 10891343.
  11. Cooke MS, Mistry N, Ladapo A, Herbert KE, Lunec J. Immunochemical quantitation of UV-induced oxidative and dimeric DNA damage to human keratinocytes. Free Radic Res. 2000 Oct;33(4):369-81. PubMed PMID: 11022846.
  12. Cooke MS, Podmore ID, Evans MD, Lunec J. Antioxidant properties of vitamin C: new issues. Cancer Detect Prev. 2001;25(6):565-6; author reply 566-7. PubMed PMID: 12132877.
  13. Cooke MS, Evans MD, Burd RM, Patel K, Barnard A, Lunec J, Hutchinson PE. Induction and excretion of ultraviolet-induced 8-oxo-2'-deoxyguanosine and thymine dimers in vivo: implications for PUVA. J Invest Dermatol. 2001 Feb;116(2):281-5. doi: 10.1046/j.1523-1747.2001.01251.x. PubMed PMID: 11180005.
  14. Cooke MS, Patel K, Ahmad J, Holloway K, Evans MD, Lunec J. Monoclonal antibody to single-stranded DNA: a potential tool for DNA repair studies. Biochem Biophys Res Commun. 2001 Jun 1;284(1):232-8. doi: 10.1006/bbrc.2001.4954. PubMed PMID: 11374895.
  15. Griffiths HR, Møller L, Bartosz G, Bast A, Bertoni-Freddari C, Collins A, Cooke M, Coolen S, Haenen G, Hoberg AM, Loft S, Lunec J, Olinski R, Parry J, Pompella A, Poulsen H, Verhagen H, Astley SB. Biomarkers. Mol Aspects Med. 2002 Feb-Jun;23(1-3):101-208. Review. PubMed PMID: 12079771.
  16. Cooke MS, Evans MD, Mistry N, Lunec J. Role of dietary antioxidants in the prevention of in vivo oxidative DNA damage. Nutr Res Rev. 2002 Jun;15(1):19-42. doi: 10.1079/NRR200132. PubMed PMID: 19087397.
  17. Cooke MS, Evans MD, Lunec J. DNA repair: insights from urinary lesion analysis. Free Radic Res. 2002 Sep;36(9):929-32. Review. PubMed PMID: 12448817.
  18. Lunec J, Holloway KA, Cooke MS, Faux S, Griffiths HR, Evans MD. Urinary 8-oxo-2'-deoxyguanosine: redox regulation of DNA repair in vivo?. Free Radic Biol Med. 2002 Oct 1;33(7):875-85. Review. PubMed PMID: 12361799.
  19. Cooke MS, Lunec J, Evans MD. Progress in the analysis of urinary oxidative DNA damage. Free Radic Biol Med. 2002 Dec 15;33(12):1601-14. Review. PubMed PMID: 12488129.
  20. Lunec J, Holloway K, Cooke M, Evans M. Redox-regulation of DNA repair. Biofactors. 2003;17(1-4):315-24. Review. PubMed PMID: 12897453.
  21. Cooke MS, Mistry N, Ahmad J, Waller H, Langford L, Bevan RJ, Evans MD, Jones GD, Herbert KE, Griffiths HR, Lunec J. Deoxycytidine glyoxal: lesion induction and evidence of repair following vitamin C supplementation in vivo. Free Radic Biol Med. 2003 Jan 15;34(2):218-25. PubMed PMID: 12521603.
  22. Evans MD, Butler JM, Nicoll K, Cooke MS, Lunec J. 17 beta-Oestradiol attenuates nucleotide excision repair. FEBS Lett. 2003 Jan 30;535(1-3):153-8. doi: 10.1016/s0014-5793(02)03898-x. PubMed PMID: 12560095.
  23. Mistry N, Podmore I, Cooke M, Butler P, Griffiths H, Herbert K, Lunec J. Novel monoclonal antibody recognition of oxidative DNA damage adduct, deoxycytidine-glyoxal. Lab Invest. 2003 Feb;83(2):241-50. PubMed PMID: 12594238.
  24. Karakoula A, Evans MD, Podmore ID, Hutchinson PE, Lunec J, Cooke MS. Quantification of UVR-induced DNA damage: global- versus gene-specific levels of thymine dimers. J Immunol Methods. 2003 Jun 1;277(1-2):27-37. doi: 10.1016/s0022-1759(03)00122-4. PubMed PMID: 12799037.
  25. Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J. 2003 Jul;17(10):1195-214. doi: 10.1096/fj.02-0752rev. Review. PubMed PMID: 12832285.
  26. Cooke MS, Podmore ID, Mistry N, Evans MD, Herbert KE, Griffiths HR, Lunec J. Immunochemical detection of UV-induced DNA damage and repair. J Immunol Methods. 2003 Sep;280(1-2):125-33. doi: 10.1016/s0022-1759(03)00269-2. PubMed PMID: 12972193.
  27. Evans MD, Cooke MS. Factors contributing to the outcome of oxidative damage to nucleic acids. Bioessays. 2004 May;26(5):533-42. doi: 10.1002/bies.20027. Review. PubMed PMID: 15112233.
  28. Evans MD, Dizdaroglu M, Cooke MS. Oxidative DNA damage and disease: induction, repair and significance. Mutat Res. 2004 Sep;567(1):1-61. doi: 10.1016/j.mrrev.2003.11.001. Review. PubMed PMID: 15341901.
  29. Habayeb OM, Taylor AH, Evans MD, Cooke MS, Taylor DJ, Bell SC, Konje JC. Plasma levels of the endocannabinoid anandamide in women--a potential role in pregnancy maintenance and labor?. J Clin Endocrinol Metab. 2004 Nov;89(11):5482-7. doi: 10.1210/jc.2004-0681. PubMed PMID: 15531501.
  30. Cooke MS, Evans MD, Dove R, Rozalski R, Gackowski D, Siomek A, Lunec J, Olinski R. DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine. Mutat Res. 2005 Jul 1;574(1-2):58-66. doi: 10.1016/j.mrfmmm.2005.01.022. Epub 2005 Apr 1. Review. PubMed PMID: 15914207.
  31. Evans MD, Cooke MS. Oxidative damage to DNA in non-malignant disease: biomarker or biohazard?. Genome Dyn. 2006;1:53-66. doi: 10.1159/000092500. Review. PubMed PMID: 18724053.
  32. Cooke MS, Robson A. Immunochemical detection of UV-induced DNA damage and repair. Methods Mol Biol. 2006;314:215-28. doi: 10.1385/1-59259-973-7:215. PubMed PMID: 16673884.
  33. Cooke MS, Olinski R, Evans MD. Does measurement of oxidative damage to DNA have clinical significance?. Clin Chim Acta. 2006 Mar;365(1-2):30-49. doi: 10.1016/j.cca.2005.09.009. Epub 2005 Oct 7. Review. PubMed PMID: 16214123.
  34. Cooke MS, Rozalski R, Dove R, Gackowski D, Siomek A, Evans MD, Olinski R. Evidence for attenuated cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine removal in cancer patients. Biol Chem. 2006 Apr;387(4):393-400. doi: 10.1515/BC.2006.053. PubMed PMID: 16606337.
  35. Olinski R, Rozalski R, Gackowski D, Foksinski M, Siomek A, Cooke MS. Urinary measurement of 8-OxodG, 8-OxoGua, and 5HMUra: a noninvasive assessment of oxidative damage to DNA. Antioxid Redox Signal. 2006 May-Jun;8(5-6):1011-9. doi: 10.1089/ars.2006.8.1011. PubMed PMID: 16771691.
  36. Cooke MS, Singh R, Hall GK, Mistry V, Duarte TL, Farmer PB, Evans MD. Evaluation of enzyme-linked immunosorbent assay and liquid chromatography-tandem mass spectrometry methodology for the analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine in saliva and urine. Free Radic Biol Med. 2006 Dec 15;41(12):1829-36. doi: 10.1016/j.freeradbiomed.2006.09.009. Epub 2006 Sep 16. PubMed PMID: 17157185.
  37. Halligan EP, Lowes D, Mistry N, Dove R, Cooke M, Evans M, Lunec J. A comparison of the gene expression profiles of CRL-1807 colonocytes exposed to endogenous AAPH-generated peroxides and exogenous peroxides from heated oil. Redox Rep. 2007;12(1):86-90. doi: 10.1179/135100007X162239. PubMed PMID: 17263917.
  38. Grigg J, Cooke MS, Panickar JR. Case 3-2007: a boy with respiratory insufficiency. N Engl J Med. 2007 May 31;356(22):2329-30; author reply 2330. PubMed PMID: 17542074.
  39. Cooke MS, Evans MD. 8-Oxo-deoxyguanosine: reduce, reuse, recycle?. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13535-6. doi: 10.1073/pnas.0706878104. Epub 2007 Aug 15. PubMed PMID: 17699620; PubMed Central PMCID: PMC1959413.
  40. Kulkarni N, Cooke MS, Grigg J. Neutrophils in induced sputum from healthy children: role of interleukin-8 and oxidative stress. Respir Med. 2007 Oct;101(10):2108-12. doi: 10.1016/j.rmed.2007.05.018. Epub 2007 Jul 6. PubMed PMID: 17618102.
  41. Cooke MS, Osborne JE, Singh R, Mistry V, Farmer PB, Evans MD, Hutchinson PE. Evidence that oxidative stress is a risk factor for the development of squamous cell carcinoma in renal transplant patients. Free Radic Biol Med. 2007 Nov 1;43(9):1328-34. doi: 10.1016/j.freeradbiomed.2007.07.024. Epub 2007 Aug 3. PubMed PMID: 17893046.
  42. Cooke MS, Olinski R, Loft S. Measurement and meaning of oxidatively modified DNA lesions in urine. Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):3-14. doi: 10.1158/1055-9965.EPI-07-0751. Review. PubMed PMID: 18199707.
  43. Mistry N, Bevan RJ, Cooke MS, Evans MD, Halligan EP, Lowes DA, Nichol K, Lunec J. Antiserum detection of reactive carbonyl species-modified DNA in human colonocytes. Free Radic Res. 2008 Apr;42(4):344-53. doi: 10.1080/10715760802008106. PubMed PMID: 18404533.
  44. Loft S, Møller P, Cooke MS, Rozalski R, Olinski R. Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker?. Eur J Nutr. 2008 May;47 Suppl 2:19-28. doi: 10.1007/s00394-008-2004-0. Review. PubMed PMID: 18458832.
  45. Evans MD, Singh R, Mistry V, Sandhu K, Farmer PB, Cooke MS. Analysis of urinary 8-oxo-7,8-dihydro-purine-2'-deoxyribonucleosides by LC-MS/MS and improved ELISA. Free Radic Res. 2008 Oct;42(10):831-40. doi: 10.1080/10715760802506323. PubMed PMID: 18985483.
  46. Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study. BMJ. 2008 Nov 3;337:a2332. doi: 10.1136/bmj.a2332. PubMed PMID: 18981029; PubMed Central PMCID: PMC2577203.
  47. Cooke MS, Duarte TL, Cooper D, Chen J, Nandagopal S, Evans MD. Combination of azathioprine and UVA irradiation is a major source of cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine. DNA Repair (Amst). 2008 Dec 1;7(12):1982-9. doi: 10.1016/j.dnarep.2008.08.007. Epub 2008 Oct 1. PubMed PMID: 18793759.
  48. Duarte TL, Cooke MS, Jones GD. Gene expression profiling reveals new protective roles for vitamin C in human skin cells. Free Radic Biol Med. 2009 Jan 1;46(1):78-87. doi: 10.1016/j.freeradbiomed.2008.09.028. Epub 2008 Oct 9. PubMed PMID: 18973801.