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  1. Khosravi MA, Abbasalipour M, Concordet JP, Berg JV, Zeinali S, Arashkia A, Azadmanesh K, Buch T, Karimipoor M. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease. Eur J Pharmacol. 2019 Apr 27;854:398-405. doi: 10.1016/j.ejphar.2019.04.042. [Epub ahead of print] PubMed PMID: 31039344.
  2. Ferreira FM, Palle P, Vom Berg J, Prajwal P, Laman JD, Buch T. Bone marrow chimeras-a vital tool in basic and translational research. J Mol Med (Berl). 2019 Apr 26;. doi: 10.1007/s00109-019-01783-z. [Epub ahead of print] Review. PubMed PMID: 31028417.
  3. Buch T, Moos K, Ferreira FM, Fröhlich H, Gebhard C, Tresch A. Benefits of a factorial design focusing on inclusion of female and male animals in one experiment. J Mol Med (Berl). 2019 Apr 13;. doi: 10.1007/s00109-019-01774-0. [Epub ahead of print] PubMed PMID: 30980104.
  4. Sparber F, De Gregorio C, Steckholzer S, Ferreira FM, Dolowschiak T, Ruchti F, Kirchner FR, Mertens S, Prinz I, Joller N, Buch T, Glatz M, Sallusto F, LeibundGut-Landmann S. The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation. Cell Host Microbe. 2019 Mar 13;25(3):389-403.e6. doi: 10.1016/j.chom.2019.02.002. PubMed PMID: 30870621.
  5. Boeck A, Landgraf-Rauf K, Vogelsang V, Siemens D, Prazeres da Costa O, Klucker E, von Mutius E, Buch T, Mansmann U, Schaub B. Ca2+ and innate immune pathways are activated and differentially expressed in childhood asthma phenotypes. Pediatr Allergy Immunol. 2018 Dec;29(8):823-833. doi: 10.1111/pai.12971. Epub 2018 Oct 9. PubMed PMID: 30102794.
  6. Seehawer M, Heinzmann F, D'Artista L, Harbig J, Roux PF, Hoenicke L, Dang H, Klotz S, Robinson L, Doré G, Rozenblum N, Kang TW, Chawla R, Buch T, Vucur M, Roth M, Zuber J, Luedde T, Sipos B, Longerich T, Heikenwälder M, Wang XW, Bischof O, Zender L. Author Correction: Necroptosis microenvironment directs lineage commitment in liver cancer. Nature. 2018 Dec;564(7735):E9. doi: 10.1038/s41586-018-0723-9. PubMed PMID: 30410124.
  7. Cruz-Aguliar RM, Wantia N, Clavel T, Vehreschild MJGT, Buch T, Bajbouj M, Haller D, Busch D, Schmid RM, Stein-Thoeringer CK. An Open-Labeled Study on Fecal Microbiota Transfer in Irritable Bowel Syndrome Patients Reveals Improvement in Abdominal Pain Associated with the Relative Abundance of Akkermansia Muciniphila. Digestion. 2018 Nov 13;:1-12. doi: 10.1159/000494252. [Epub ahead of print] PubMed PMID: 30423561.
  8. Stickel F, Buch S, Nischalke HD, Weiss KH, Gotthardt D, Fischer J, Rosendahl J, Marot A, Elamly M, Casper M, Lammert F, McQuillin A, Zopf S, Spengler U, Marhenke S, Kirstein MM, Vogel A, Eyer F, von Felden J, Wege H, Buch T, Schafmayer C, Braun F, Deltenre P, Berg T, Morgan MY, Hampe J. Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis. Am J Gastroenterol. 2018 Oct;113(10):1475-1483. doi: 10.1038/s41395-018-0041-8. Epub 2018 Mar 13. PubMed PMID: 29535416.
  9. Seehawer M, Heinzmann F, D'Artista L, Harbig J, Roux PF, Hoenicke L, Dang H, Klotz S, Robinson L, Doré G, Rozenblum N, Kang TW, Chawla R, Buch T, Vucur M, Roth M, Zuber J, Luedde T, Sipos B, Longerich T, Heikenwälder M, Wang XW, Bischof O, Zender L. Necroptosis microenvironment directs lineage commitment in liver cancer. Nature. 2018 Oct;562(7725):69-75. doi: 10.1038/s41586-018-0519-y. Epub 2018 Sep 12. PubMed PMID: 30209397.
  10. Stickel F, Buch S, Nischalke HD, Weiss KH, Gotthardt D, Fischer J, Rosendahl J, Marot A, Elamly M, Casper M, Lammert F, McQuillin A, Zopf S, Spengler U, Marhenke S, Kirstein MM, Vogel A, Eyer F, von Felden J, Wege H, Buch T, Schafmayer C, Braun F, Deltenre P, Berg T, Morgan MY, Hampe J. Correction: Genetic Variants in PNPLA3 and TM6SF2 Predispose to the Development of Hepatocellular Carcinoma in Individuals With Alcohol-Related Cirrhosis. Am J Gastroenterol. 2018 Jul;113(7):1099. doi: 10.1038/s41395-018-0118-4. PubMed PMID: 29895985.
  11. Wartewig T, Kurgyis Z, Keppler S, Pechloff K, Hameister E, Öllinger R, Maresch R, Buch T, Steiger K, Winter C, Rad R, Ruland J. Erratum: PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis. Nature. 2018 Jan 11;553(7687):238. doi: 10.1038/nature25142. Epub 2017 Nov 29. PubMed PMID: 29186126.
  12. Hahn M, Bürckert JP, Luttenberger CA, Klebow S, Hess M, Al-Maarri M, Vogt M, Reißig S, Hallek M, Wienecke-Baldacchino A, Buch T, Muller CP, Pallasch CP, Wunderlich FT, Waisman A, Hövelmeyer N. Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-κB signaling. Leukemia. 2018 Jan;32(1):72-82. doi: 10.1038/leu.2017.168. Epub 2017 Jun 1. PubMed PMID: 28566736.
  13. Wartewig T, Kurgyis Z, Keppler S, Pechloff K, Hameister E, Öllinger R, Maresch R, Buch T, Steiger K, Winter C, Rad R, Ruland J. PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis. Nature. 2017 Dec 7;552(7683):121-125. doi: 10.1038/nature24649. Epub 2017 Nov 15. PubMed PMID: 29143824; PubMed Central PMCID: PMC5821214.
  14. Palle P, Ferreira FM, Methner A, Buch T. The more the merrier? Scoring, statistics and animal welfare in experimental autoimmune encephalomyelitis. Lab Anim. 2016 Dec;50(6):427-432. doi: 10.1177/0023677216675008. PubMed PMID: 27909192.
  15. Sujino T, London M, Hoytema van Konijnenburg DP, Rendon T, Buch T, Silva HM, Lafaille JJ, Reis BS, Mucida D. Tissue adaptation of regulatory and intraepithelial CD4⁺ T cells controls gut inflammation. Science. 2016 Jun 24;352(6293):1581-6. doi: 10.1126/science.aaf3892. Epub 2016 Jun 2. PubMed PMID: 27256884; PubMed Central PMCID: PMC4968079.
  16. Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Sander J, Lehmann C, Thabet Y, Shinde PV, Schmidleithner L, Köhne M, Trebicka J, Schierwagen R, Hofmann A, Popov A, Lang KS, Oxenius A, Buch T, Kurts C, Heikenwalder M, Fätkenheuer G, Lang PA, Hartmann P, Knolle PA, Schultze JL. Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infection. Nat Immunol. 2016 May;17(5):593-603. doi: 10.1038/ni.3399. Epub 2016 Mar 7. PubMed PMID: 26950238.
  17. Janowski R, Heinz GA, Schlundt A, Wommelsdorf N, Brenner S, Gruber AR, Blank M, Buch T, Buhmann R, Zavolan M, Niessing D, Heissmeyer V, Sattler M. Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40. Nat Commun. 2016 Mar 24;7:11032. doi: 10.1038/ncomms11032. PubMed PMID: 27010430; PubMed Central PMCID: PMC5603727.
  18. Beil-Wagner J, Dössinger G, Schober K, vom Berg J, Tresch A, Grandl M, Palle P, Mair F, Gerhard M, Becher B, Busch DH, Buch T. T cell-specific inactivation of mouse CD2 by CRISPR/Cas9. Sci Rep. 2016 Feb 23;6:21377. doi: 10.1038/srep21377. PubMed PMID: 26903281; PubMed Central PMCID: PMC4763270.
  19. Hensel T, Giorgi C, Schmidt O, Calzada-Wack J, Neff F, Buch T, Niggli FK, Schäfer BW, Burdach S, Richter GH. Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma. Oncotarget. 2016 Jan 12;7(2):1451-63. doi: 10.18632/oncotarget.6385. PubMed PMID: 26623725; PubMed Central PMCID: PMC4811472.
  20. Agelopoulos K, Richter GH, Schmidt E, Dirksen U, von Heyking K, Moser B, Klein HU, Kontny U, Dugas M, Poos K, Korsching E, Buch T, Weckesser M, Schulze I, Besoke R, Witten A, Stoll M, Köhler G, Hartmann W, Wardelmann E, Rossig C, Baumhoer D, Jürgens H, Burdach S, Berdel WE, Müller-Tidow C. Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma. Clin Cancer Res. 2015 Nov 1;21(21):4935-46. doi: 10.1158/1078-0432.CCR-14-2744. Epub 2015 Jul 15. PubMed PMID: 26179511.
  21. Dufner A, Kisser A, Niendorf S, Basters A, Reissig S, Schönle A, Aichem A, Kurz T, Schlosser A, Yablonski D, Groettrup M, Buch T, Waisman A, Schamel WW, Prinz M, Knobeloch KP. The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells. Nat Immunol. 2015 Sep;16(9):950-60. doi: 10.1038/ni.3230. Epub 2015 Jul 27. PubMed PMID: 26214742.
  22. Stenger B, Zehfuss F, Mückter H, Schmidt A, Balszuweit F, Schäfer E, Büch T, Gudermann T, Thiermann H, Steinritz D. Activation of the chemosensing transient receptor potential channel A1 (TRPA1) by alkylating agents. Arch Toxicol. 2015 Sep;89(9):1631-43. doi: 10.1007/s00204-014-1414-4. Epub 2014 Nov 14. PubMed PMID: 25395009.
  23. Zoller V, Laguna AL, Prazeres Da Costa O, Buch T, Göke B, Storr M. [Fecal microbiota transfer (FMT) in a patient with refractory irritable bowel syndrome]. Dtsch Med Wochenschr. 2015 Aug;140(16):1232-6. doi: 10.1055/s-0041-103798. Epub 2015 Aug 11. PubMed PMID: 26261935.
  24. Erny D, Hrabě de Angelis AL, Jaitin D, Wieghofer P, Staszewski O, David E, Keren-Shaul H, Mahlakoiv T, Jakobshagen K, Buch T, Schwierzeck V, Utermöhlen O, Chun E, Garrett WS, McCoy KD, Diefenbach A, Staeheli P, Stecher B, Amit I, Prinz M. Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci. 2015 Jul;18(7):965-77. doi: 10.1038/nn.4030. Epub 2015 Jun 1. PubMed PMID: 26030851; PubMed Central PMCID: PMC5528863.
  25. Locatelli G, Baggiolini A, Schreiner B, Palle P, Waisman A, Becher B, Buch T. Mature oligodendrocytes actively increase in vivo cytoskeletal plasticity following CNS damage. J Neuroinflammation. 2015 Apr 2;12:62. doi: 10.1186/s12974-015-0271-2. PubMed PMID: 25889302; PubMed Central PMCID: PMC4404661.
  26. Kong B, Bruns P, Raulefs S, Rieder S, Paul L, Prazeresda Costa O, Buch T, Theis FJ, Michalski CW, Kleeff J. Metabolism gene signatures and surgical site infections in abdominal surgery. Int J Surg. 2015 Feb;14:67-74. doi: 10.1016/j.ijsu.2015.01.009. Epub 2015 Jan 16. PubMed PMID: 25599917.
  27. Raedler D, Ballenberger N, Klucker E, Böck A, Otto R, Prazeres da Costa O, Holst O, Illig T, Buch T, von Mutius E, Schaub B. Identification of novel immune phenotypes for allergic and nonallergic childhood asthma. J Allergy Clin Immunol. 2015 Jan;135(1):81-91. doi: 10.1016/j.jaci.2014.07.046. Epub 2014 Sep 13. PubMed PMID: 25226851.
  28. Straubinger K, Paul S, Prazeres da Costa O, Ritter M, Buch T, Busch DH, Layland LE, Prazeres da Costa CU. Maternal immune response to helminth infection during pregnancy determines offspring susceptibility to allergic airway inflammation. J Allergy Clin Immunol. 2014 Dec;134(6):1271-1279.e10. doi: 10.1016/j.jaci.2014.05.034. Epub 2014 Jul 18. PubMed PMID: 25042744.
  29. Vahl JC, Drees C, Heger K, Heink S, Fischer JC, Nedjic J, Ohkura N, Morikawa H, Poeck H, Schallenberg S, Rieß D, Hein MY, Buch T, Polic B, Schönle A, Zeiser R, Schmitt-Gräff A, Kretschmer K, Klein L, Korn T, Sakaguchi S, Schmidt-Supprian M. Continuous T cell receptor signals maintain a functional regulatory T cell pool. Immunity. 2014 Nov 20;41(5):722-36. doi: 10.1016/j.immuni.2014.10.012. Epub 2014 Nov 6. PubMed PMID: 25464853.
  30. Hu D, Barajas-Martínez H, Pfeiffer R, Dezi F, Pfeiffer J, Buch T, Betzenhauser MJ, Belardinelli L, Kahlig KM, Rajamani S, DeAntonio HJ, Myerburg RJ, Ito H, Deshmukh P, Marieb M, Nam GB, Bhatia A, Hasdemir C, Haïssaguerre M, Veltmann C, Schimpf R, Borggrefe M, Viskin S, Antzelevitch C. Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome. J Am Coll Cardiol. 2014 Jul 8;64(1):66-79. doi: 10.1016/j.jacc.2014.04.032. PubMed PMID: 24998131; PubMed Central PMCID: PMC4116276.
  31. Turqueti-Neves A, Otte M, Prazeres da Costa O, Höpken UE, Lipp M, Buch T, Voehringer D. B-cell-intrinsic STAT6 signaling controls germinal center formation. Eur J Immunol. 2014 Jul;44(7):2130-8. doi: 10.1002/eji.201344203. Epub 2014 May 21. PubMed PMID: 24777733.
  32. Heinemann C, Heink S, Petermann F, Vasanthakumar A, Rothhammer V, Doorduijn E, Mitsdoerffer M, Sie C, Prazeres da Costa O, Buch T, Hemmer B, Oukka M, Kallies A, Korn T. IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1. Nat Commun. 2014 May 6;5:3770. doi: 10.1038/ncomms4770. PubMed PMID: 24796719.
  33. Prazeres da Costa O, Hoffman A, Rey JW, Mansmann U, Buch T, Tresch A. Selection of higher order regression models in the analysis of multi-factorial transcription data. PLoS One. 2014;9(3):e91840. doi: 10.1371/journal.pone.0091840. eCollection 2014. PubMed PMID: 24658540; PubMed Central PMCID: PMC3962375.
  34. Beil J, Buch T. Generation of bacterial artificial chromosome (BAC) transgenic mice. Methods Mol Biol. 2014;1194:157-69. doi: 10.1007/978-1-4939-1215-5_8. PubMed PMID: 25064102.
  35. Sledzińska A, Fairbairn L, Buch T. Manipulation of T cell function and conditional gene targeting in T cells. Methods Mol Biol. 2014;1193:153-69. doi: 10.1007/978-1-4939-1212-4_15. PubMed PMID: 25151005.
  36. Grunewald TG, Willier S, Janik D, Unland R, Reiss C, Prazeres da Costa O, Buch T, Dirksen U, Richter GH, Neff F, Burdach S, Butt E. The Zyxin-related protein thyroid receptor interacting protein 6 (TRIP6) is overexpressed in Ewing's sarcoma and promotes migration, invasion and cell growth. Biol Cell. 2013 Nov;105(11):535-47. doi: 10.1111/boc.201300041. Epub 2013 Sep 18. PubMed PMID: 24033704.
  37. Sledzińska A, Hemmers S, Mair F, Gorka O, Ruland J, Fairbairn L, Nissler A, Müller W, Waisman A, Becher B, Buch T. TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function. PLoS Biol. 2013 Oct;11(10):e1001674. doi: 10.1371/journal.pbio.1001674. Epub 2013 Oct 8. PubMed PMID: 24115907; PubMed Central PMCID: PMC3792861.
  38. Kreslavsky T, Kim HJ, Koralov SB, Ghitza D, Buch T, Cantor H, Rajewsky K, von Boehmer H. Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes. J Exp Med. 2013 Sep 23;210(10):1911-8. doi: 10.1084/jem.20130876. Epub 2013 Aug 26. PubMed PMID: 23980099; PubMed Central PMCID: PMC3782038.
  39. Bäck CM, Stohr S, Schäfer EA, Biebermann H, Boekhoff I, Breit A, Gudermann T, Büch TR. TSH induces metallothionein 1 in thyrocytes via Gq/11- and PKC-dependent signaling. J Mol Endocrinol. 2013;51(1):79-90. doi: 10.1530/JME-12-0200. Print 2013. PubMed PMID: 23613280.
  40. Demircik F, Buch T, Waisman A. Efficient B cell depletion via diphtheria toxin in CD19-Cre/iDTR mice. PLoS One. 2013;8(3):e60643. doi: 10.1371/journal.pone.0060643. Epub 2013 Mar 27. PubMed PMID: 23544158; PubMed Central PMCID: PMC3609725.
  41. Buch TN, Holm J, Munck LK. [Extensive thromboembolism after cardioversion in a patient treated with dabigatran]. Ugeskr Laeger. 2013 Feb 4;175(6):333-4. PubMed PMID: 23402235.
  42. Kowalska E, Ripperger JA, Hoegger DC, Bruegger P, Buch T, Birchler T, Mueller A, Albrecht U, Contaldo C, Brown SA. NONO couples the circadian clock to the cell cycle. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1592-9. doi: 10.1073/pnas.1213317110. Epub 2012 Dec 24. PubMed PMID: 23267082; PubMed Central PMCID: PMC3562797.
  43. Hauer K, Calzada-Wack J, Steiger K, Grunewald TG, Baumhoer D, Plehm S, Buch T, Prazeres da Costa O, Esposito I, Burdach S, Richter GH. DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma. Cancer Res. 2013 Jan 15;73(2):967-77. doi: 10.1158/0008-5472.CAN-12-1492. Epub 2012 Nov 30. PubMed PMID: 23204234.
  44. Huber M, Heink S, Pagenstecher A, Reinhard K, Ritter J, Visekruna A, Guralnik A, Bollig N, Jeltsch K, Heinemann C, Wittmann E, Buch T, Prazeres da Costa O, Brüstle A, Brenner D, Mak TW, Mittrücker HW, Tackenberg B, Kamradt T, Lohoff M. IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. J Clin Invest. 2013 Jan;123(1):247-60. doi: 10.1172/JCI63681. Epub 2012 Dec 10. PubMed PMID: 23221338; PubMed Central PMCID: PMC3533283.
  45. Hermann M, Maeder ML, Rector K, Ruiz J, Becher B, Bürki K, Khayter C, Aguzzi A, Joung JK, Buch T, Pelczar P. Evaluation of OPEN zinc finger nucleases for direct gene targeting of the ROSA26 locus in mouse embryos. PLoS One. 2012;7(9):e41796. doi: 10.1371/journal.pone.0041796. Epub 2012 Sep 6. PubMed PMID: 22970113; PubMed Central PMCID: PMC3435328.
  46. Beil J, Fairbairn L, Pelczar P, Buch T. Is BAC transgenesis obsolete? State of the art in the era of designer nucleases. J Biomed Biotechnol. 2012;2012:308414. doi: 10.1155/2012/308414. Epub 2012 Jul 30. PubMed PMID: 22899885; PubMed Central PMCID: PMC3413995.
  47. Krautler NJ, Kana V, Kranich J, Tian Y, Perera D, Lemm D, Schwarz P, Armulik A, Browning JL, Tallquist M, Buch T, Oliveira-Martins JB, Zhu C, Hermann M, Wagner U, Brink R, Heikenwalder M, Aguzzi A. Follicular dendritic cells emerge from ubiquitous perivascular precursors. Cell. 2012 Jul 6;150(1):194-206. doi: 10.1016/j.cell.2012.05.032. PubMed PMID: 22770220; PubMed Central PMCID: PMC3704230.
  48. Fu Q, Gremeaux L, Luque RM, Liekens D, Chen J, Buch T, Waisman A, Kineman R, Vankelecom H. The adult pituitary shows stem/progenitor cell activation in response to injury and is capable of regeneration. Endocrinology. 2012 Jul;153(7):3224-35. doi: 10.1210/en.2012-1152. Epub 2012 Apr 19. PubMed PMID: 22518061.
  49. Frankenberger M, Hofer TP, Marei A, Dayyani F, Schewe S, Strasser C, Aldraihim A, Stanzel F, Lang R, Hoffmann R, Prazeres da Costa O, Buch T, Ziegler-Heitbrock L. Transcript profiling of CD16-positive monocytes reveals a unique molecular fingerprint. Eur J Immunol. 2012 Apr;42(4):957-74. doi: 10.1002/eji.201141907. PubMed PMID: 22531920.
  50. Linneberg A, Rasmussen M, Buch TF, Wester A, Malm L, Fannikke G, Vest S. A randomised study of the effects of supplemental exercise sessions after a 7-week chronic obstructive pulmonary disease rehabilitation program. Clin Respir J. 2012 Apr;6(2):112-9. doi: 10.1111/j.1752-699X.2011.00256.x. Epub 2011 Jul 6. PubMed PMID: 21651747.