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Kichkin E, Visvanathan A, Lovicu FJ, Shu DY, Das SJ, Reddel SW, McCann EP, Zhang KY, Williams KL, Blair IP, Phillips WD. Postnatal Development of Spasticity Following Transgene Insertion in the Mouse βIV Spectrin Gene (SPTBN4). J Neuromuscul Dis. 2017;4(2):159-164. doi: 10.3233/JND-160197. PubMed PMID: 28582869.
Shu DY, Wojciechowski MC, Lovicu FJ. Bone Morphogenetic Protein-7 Suppresses TGFβ2-Induced Epithelial-Mesenchymal Transition in the Lens: Implications for Cataract Prevention. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):781-796. doi: 10.1167/iovs.16-20611. PubMed PMID: 28152139; PubMed Central PMCID: PMC5295783.
Shu DY, Ong K, Lovicu FJ. Histopathology of Subcapsular Cataract in a Patient with Atopic Dermatitis. Optom Vis Sci. 2017 Feb;94(2):270-276. doi: 10.1097/OPX.0000000000001011. PubMed PMID: 27801692.
Wojciechowski MC, Mahmutovic L, Shu DY, Lovicu FJ. ERK1/2 signaling is required for the initiation but not progression of TGFβ-induced lens epithelial to mesenchymal transition (EMT). Exp Eye Res. 2017 Jun;159:98-113. doi: 10.1016/j.exer.2017.03.012. Epub 2017 Mar 30. PubMed PMID: 28365272; PubMed Central PMCID: PMC5476419.
Shu DY, Lovicu FJ. Myofibroblast transdifferentiation: The dark force in ocular wound healing and fibrosis. Prog Retin Eye Res. 2017 Sep;60:44-65. doi: 10.1016/j.preteyeres.2017.08.001. Epub 2017 Aug 12. Review. PubMed PMID: 28807717; PubMed Central PMCID: PMC5600870.
Wojciechowski MC, Shu DY, Lovicu FJ. ERK1/2-Dependent Gene Expression Contributing to TGFβ-Induced Lens EMT. Curr Eye Res. 2018 Aug;43(8):986-997. doi: 10.1080/02713683.2018.1464193. Epub 2018 Apr 23. PubMed PMID: 29652528.
Shu DY, Wojciechowski M, Lovicu FJ. ERK1/2-mediated EGFR-signaling is required for TGFβ-induced lens epithelial-mesenchymal transition. Exp Eye Res. 2019 Jan;178:108-121. doi: 10.1016/j.exer.2018.09.021. Epub 2018 Oct 2. PubMed PMID: 30290164.
Shu DY, Hutcheon AEK, Zieske JD, Guo X. Epidermal Growth Factor Stimulates Transforming Growth Factor-Beta Receptor Type II Expression In Corneal Epithelial Cells. Sci Rep. 2019 May 30;9(1):8079. doi: 10.1038/s41598-019-42969-2. PubMed PMID: 31147562; PubMed Central PMCID: PMC6542834.
Rosales MAB, Shu DY, Iacovelli J, Saint-Geniez M. Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration. Life Sci Alliance. 2019 Jun;2(3). doi: 10.26508/lsa.201800212. Print 2019 Jun. PubMed PMID: 31101737; PubMed Central PMCID: PMC6526284.
Shu DY, Lovicu FJ. Enhanced EGF receptor-signaling potentiates TGFβ-induced lens epithelial-mesenchymal transition. Exp Eye Res. 2019 Aug;185:107693. doi: 10.1016/j.exer.2019.107693. Epub 2019 Jun 12. PubMed PMID: 31201806.
Shu DY, Butcher E, Saint-Geniez M. EMT and EndMT: Emerging Roles in Age-Related Macular Degeneration. Int J Mol Sci. 2020 Jun 16;21(12). doi: 10.3390/ijms21124271. Review. PubMed PMID: 32560057; PubMed Central PMCID: PMC7349630.
Shu DY, Butcher ER, Saint-Geniez M. Suppression of PGC-1α Drives Metabolic Dysfunction in TGFβ2-Induced EMT of Retinal Pigment Epithelial Cells. Int J Mol Sci. 2021 Apr 29;22(9). doi: 10.3390/ijms22094701. PubMed PMID: 33946753; PubMed Central PMCID: PMC8124188.
Shu DY, Ng K, Wishart TFL, Chui J, Lundmark M, Flokis M, Lovicu FJ. Contrasting roles for BMP-4 and ventromorphins (BMP agonists) in TGFβ-induced lens EMT. Exp Eye Res. 2021 May;206:108546. doi: 10.1016/j.exer.2021.108546. Epub 2021 Mar 24. PubMed PMID: 33773977.
Wishart TFL, Flokis M, Shu DY, Das SJ, Lovicu FJ. Hallmarks of lens aging and cataractogenesis. Exp Eye Res. 2021 Sep;210:108709. doi: 10.1016/j.exer.2021.108709. Epub 2021 Jul 30. PubMed PMID: 34339681.
Shu DY, Lovicu FJ. Insights into Bone Morphogenetic Protein-(BMP-) Signaling in Ocular Lens Biology and Pathology. Cells. 2021 Sep 30;10(10). doi: 10.3390/cells10102604. Review. PubMed PMID: 34685584; PubMed Central PMCID: PMC8533954.
Shu DY, Frank SI, Fitch TC, Karg MM, Butcher ER, Nnuji-John E, Kim LA, Saint-Geniez M. Dimethyl Fumarate Blocks Tumor Necrosis Factor-Alpha-Driven Inflammation and Metabolic Rewiring in the Retinal Pigment Epithelium. Front Mol Neurosci. 2022;15:896786. doi: 10.3389/fnmol.2022.896786. eCollection 2022. PubMed PMID: 35813071; PubMed Central PMCID: PMC9259930.
Shu DY, Chaudhary S, Cho KS, Lennikov A, Miller WP, Thorn DC, Yang M, McKay TB. Role of Oxidative Stress in Ocular Diseases: A Balancing Act. Metabolites. 2023 Jan 27;13(2). doi: 10.3390/metabo13020187. Review. PubMed PMID: 36837806; PubMed Central PMCID: PMC9960073.
Ng PQ, Saint-Geniez M, Kim LA, Shu DY. Divergent Metabolomic Signatures of TGFβ2 and TNFα in the Induction of Retinal Epithelial-Mesenchymal Transition. Metabolites. 2023 Jan 31;13(2). doi: 10.3390/metabo13020213. PubMed PMID: 36837832; PubMed Central PMCID: PMC9966219.
Fitch TC, Frank SI, Li YK, Saint-Geniez M, Kim LA, Shu DY. Real-Time Analysis of Bioenergetics in Primary Human Retinal Pigment Epithelial Cells Using High-Resolution Respirometry. J Vis Exp. 2023 Feb 3;(192). doi: 10.3791/64572. PubMed PMID: 36804905.
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