My Bibliography

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Jiang Y, Scott KL, Kwak SJ, Chen R, Mardon G. Sds22/PP1 links epithelial integrity and tumor suppression via regulation of myosin II and JNK signaling. Oncogene. 2011 Jul 21;30(29):3248-60. doi: 10.1038/onc.2011.46. Epub 2011 Mar 14. PubMed PMID: 21399659; PubMed Central PMCID: PMC3141090.

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Jiang Y, Jo AY, Graff JM. SnapShot: adipocyte life cycle. Cell. 2012 Jul 6;150(1):234-234.e2. doi: 10.1016/j.cell.2012.06.022. PubMed PMID: 22770223.

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Atkins M, Jiang Y, Sansores-Garcia L, Jusiak B, Halder G, Mardon G. Dynamic rewiring of the Drosophila retinal determination network switches its function from selector to differentiation. PLoS Genet. 2013 Aug;9(8):e1003731. doi: 10.1371/journal.pgen.1003731. Epub 2013 Aug 29. PubMed PMID: 24009524; PubMed Central PMCID: PMC3757064.

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Li Y, Jiang Y, Chen Y, Karandikar U, Hoffman K, Chattopadhyay A, Mardon G, Chen R. optix functions as a link between the retinal determination network and the dpp pathway to control morphogenetic furrow progression in Drosophila. Dev Biol. 2013 Sep 1;381(1):50-61. doi: 10.1016/j.ydbio.2013.06.015. Epub 2013 Jun 20. PubMed PMID: 23792115; PubMed Central PMCID: PMC3742619.

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Jiang Y, Berry DC, Tang W, Graff JM. Independent stem cell lineages regulate adipose organogenesis and adipose homeostasis. Cell Rep. 2014 Nov 6;9(3):1007-22. doi: 10.1016/j.celrep.2014.09.049. Epub 2014 Oct 23. PubMed PMID: 25437556; PubMed Central PMCID: PMC4250841.

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Berry DC, Jiang Y, Graff JM. Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function. Nat Commun. 2016 Jan 5;7:10184. doi: 10.1038/ncomms10184. PubMed PMID: 26729601; PubMed Central PMCID: PMC4728429.

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Berry DC, Jiang Y, Graff JM. Emerging Roles of Adipose Progenitor Cells in Tissue Development, Homeostasis, Expansion and Thermogenesis. Trends Endocrinol Metab. 2016 Aug;27(8):574-585. doi: 10.1016/j.tem.2016.05.001. Epub 2016 Jun 1. Review. PubMed PMID: 27262681; PubMed Central PMCID: PMC10947416.

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Berry DC, Jiang Y, Arpke RW, Close EL, Uchida A, Reading D, Berglund ED, Kyba M, Graff JM. Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans. Cell Metab. 2017 Jan 10;25(1):166-181. doi: 10.1016/j.cmet.2016.10.023. Epub 2016 Nov 23. PubMed PMID: 27889388; PubMed Central PMCID: PMC5226893.

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Jiang Y, Berry DC, Jo A, Tang W, Arpke RW, Kyba M, Graff JM. A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion. Nat Commun. 2017 Jun 26;8:15926. doi: 10.1038/ncomms15926. PubMed PMID: 28649987; PubMed Central PMCID: PMC5490270.

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Jiang Y, Berry DC, Graff JM. Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation. Elife. 2017 Oct 11;6. doi: 10.7554/eLife.30329. PubMed PMID: 29019320; PubMed Central PMCID: PMC5667933.

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Acharya A, Berry DC, Zhang H, Jiang Y, Jones BT, Hammer RE, Graff JM, Mendell JT. miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19. Genes Dev. 2019 Oct 1;33(19-20):1367-1380. doi: 10.1101/gad.328955.119. Epub 2019 Sep 5. PubMed PMID: 31488578; PubMed Central PMCID: PMC6771383.

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Yuan Y, Xu P, Jiang Q, Cai X, Wang T, Peng W, Sun J, Zhu C, Zhang C, Yue D, He Z, Yang J, Zeng Y, Du M, Zhang F, Ibrahimi L, Schaul S, Jiang Y, Wang J, Sun J, Wang Q, Liu L, Wang S, Wang L, Zhu X, Gao P, Xi Q, Yin C, Li F, Xu G, Zhang Y, Shu G. Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation. EMBO J. 2020 Apr 1;39(7):e103304. doi: 10.15252/embj.2019103304. Epub 2020 Feb 27. PubMed PMID: 32104923; PubMed Central PMCID: PMC7110140.

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Shin S, Pang Y, Park J, Liu L, Lukas BE, Kim SH, Kim KW, Xu P, Berry DC, Jiang Y. Dynamic control of adipose tissue development and adult tissue homeostasis by platelet-derived growth factor receptor alpha. Elife. 2020 Jun 19;9. doi: 10.7554/eLife.56189. PubMed PMID: 32553115; PubMed Central PMCID: PMC7338051.

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Shin S, El-Sabbagh AS, Lukas BE, Tanneberger SJ, Jiang Y. Adipose stem cells in obesity: challenges and opportunities. Biosci Rep. 2020 Jun 26;40(6). doi: 10.1042/BSR20194076. Review. PubMed PMID: 32452515; PubMed Central PMCID: PMC7284323.

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Park J, Shin S, Liu L, Jahan I, Ong SG, Xu P, Berry DC, Jiang Y. Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue. Dev Cell. 2021 Apr 5;56(7):985-999.e4. doi: 10.1016/j.devcel.2021.02.018. Epub 2021 Mar 11. PubMed PMID: 33711247; PubMed Central PMCID: PMC8026751.

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Paris S, Ekeanyanwu R, Jiang Y, Davis D, Spechler SJ, Souza RF. Obesity and its effects on the esophageal mucosal barrier. Am J Physiol Gastrointest Liver Physiol. 2021 Sep 1;321(3):G335-G343. doi: 10.1152/ajpgi.00199.2021. Epub 2021 Aug 18. Review. PubMed PMID: 34405732.

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Wang Z, Peet NP, Zhang P, Jiang Y, Rong L. Current Development of Glioblastoma Therapeutic Agents. Mol Cancer Ther. 2021 Sep;20(9):1521-1532. doi: 10.1158/1535-7163.MCT-21-0159. Epub 2021 Jun 25. Review. PubMed PMID: 34172531.

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Griffiths A, Wang J, Song Q, Iyamu ID, Liu L, Park J, Jiang Y, Huang R, Song Z. Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes. Am J Physiol Cell Physiol. 2021 Sep 1;321(3):C585-C595. doi: 10.1152/ajpcell.00195.2021. Epub 2021 Aug 11. PubMed PMID: 34378991; PubMed Central PMCID: PMC8461816.

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Ye H, Feng B, Wang C, Saito K, Yang Y, Ibrahimi L, Schaul S, Patel N, Saenz L, Luo P, Lai P, Torres V, Kota M, Dixit D, Cai X, Qu N, Hyseni I, Yu K, Jiang Y, Tong Q, Sun Z, Arenkiel BR, He Y, Xu P, Xu Y. An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity. Sci Adv. 2022 Jan 21;8(3):eabk0185. doi: 10.1126/sciadv.abk0185. Epub 2022 Jan 19. PubMed PMID: 35044814; PubMed Central PMCID: PMC8769556.

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Wang Z, Kim J, Zhang P, Galvan Achi JM, Jiang Y, Rong L. Current therapy and development of therapeutic agents for lung cancer. Cell Insight. 2022 Apr;1(2):100015. doi: 10.1016/j.cellin.2022.100015. eCollection 2022 Apr. Review. PubMed PMID: 37193130; PubMed Central PMCID: PMC10120308.

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Yuan Y, Zhu C, Wang Y, Sun J, Feng J, Ma Z, Li P, Peng W, Yin C, Xu G, Xu P, Jiang Y, Jiang Q, Shu G. α-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling. Sci Adv. 2022 May 6;8(18):eabn2879. doi: 10.1126/sciadv.abn2879. Epub 2022 May 4. PubMed PMID: 35507647; PubMed Central PMCID: PMC9067931.

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Torres Irizarry VC, Jiang Y, He Y, Xu P. Hypothalamic Estrogen Signaling and Adipose Tissue Metabolism in Energy Homeostasis. Front Endocrinol (Lausanne). 2022;13:898139. doi: 10.3389/fendo.2022.898139. eCollection 2022. Review. PubMed PMID: 35757435; PubMed Central PMCID: PMC9218066.

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Song Q, Chen Y, Ding Q, Griffiths A, Liu L, Park J, Liew CW, Nieto N, Li S, Dou X, Jiang Y, Song Z. mTORC1 inhibition uncouples lipolysis and thermogenesis in white adipose tissue to contribute to alcoholic liver disease. Hepatol Commun. 2023 Mar 1;7(3):e0059. doi: 10.1097/HC9.0000000000000059. eCollection 2023 Mar 1. PubMed PMID: 36757400; PubMed Central PMCID: PMC9915967.

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Benvie AM, Lee D, Steiner BM, Xue S, Jiang Y, Berry DC. Age-dependent Pdgfrβ signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice. Nat Commun. 2023 Mar 31;14(1):1806. doi: 10.1038/s41467-023-37386-z. PubMed PMID: 37002214; PubMed Central PMCID: PMC10066302.

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Wu R, Park J, Qian Y, Shi Z, Hu R, Yuan Y, Xiong S, Wang Z, Yan G, Ong SG, Song Q, Song Z, Mahmoud AM, Xu P, He C, Arpke RW, Kyba M, Shu G, Jiang Q, Jiang Y. Genetically prolonged beige fat in male mice confers long-lasting metabolic health. Nat Commun. 2023 May 12;14(1):2731. doi: 10.1038/s41467-023-38471-z. PubMed PMID: 37169793; PubMed Central PMCID: PMC10175245.

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Yuan Y, Shi Z, Xiong S, Hu R, Song Q, Song Z, Ong SG, Jiang Y. Differential roles of insulin receptor in adipocyte progenitor cells in mice. Mol Cell Endocrinol. 2023 Aug 1;573:111968. doi: 10.1016/j.mce.2023.111968. Epub 2023 May 25. PubMed PMID: 37244600; PubMed Central PMCID: PMC10846871.

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Park J, Hu R, Xiong S, Qian Y, El-Sabbagh AS, Ibrahim M, Song Q, Yan G, Song Z, Mahmoud AM, He Y, Layden BT, Chen J, Ong SG, Xu P, Jiang Y. Estrogen prevents age-dependent beige adipogenesis failure through NAMPT-controlled ER stress pathway. bioRxiv. 2023 Sep 1;. doi: 10.1101/2023.08.31.555821. PubMed PMID: 37693431; PubMed Central PMCID: PMC10491185.

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Benvie AM, Lee D, Jiang Y, Berry DC. Platelet-derived growth factor receptor beta is required for embryonic specification and confinement of the adult white adipose lineage. iScience. 2024 Jan 19;27(1):108682. doi: 10.1016/j.isci.2023.108682. eCollection 2024 Jan 19. PubMed PMID: 38235323; PubMed Central PMCID: PMC10792241.

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Song Q, Hwang CL, Li Y, Wang J, Park J, Lee SM, Sun Z, Sun J, Xia Y, Nieto N, Cordoba-Chacon J, Jiang Y, Dou X, Song Z. Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation. Metabolism. 2024 Feb;151:155740. doi: 10.1016/j.metabol.2023.155740. Epub 2023 Nov 22. PubMed PMID: 37995805; PubMed Central PMCID: PMC11905506.

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Shi Z, Xiong S, Hu R, Wang Z, Park J, Qian Y, Wang J, Bhalla P, Velupally N, Song Q, Song Z, Jeon MS, Zhang KK, Xie L, Layden BT, Ong SG, Jiang Y. The Notch-PDGFRβ axis suppresses brown adipocyte progenitor differentiation in early post-natal mice. Dev Cell. 2024 May 20;59(10):1233-1251.e5. doi: 10.1016/j.devcel.2024.03.012. Epub 2024 Apr 2. PubMed PMID: 38569546; PubMed Central PMCID: PMC11874136.

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Lee D, Benvie AM, Steiner BM, Kolba NJ, Ford JG, McCabe SM, Jiang Y, Berry DC. Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue. Cell Rep. 2024 May 28;43(5):114169. doi: 10.1016/j.celrep.2024.114169. Epub 2024 Apr 27. PubMed PMID: 38678562; PubMed Central PMCID: PMC11413973.

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Park J, Hu R, Qian Y, Xiong S, El-Sabbagh AS, Ibrahim M, Wang J, Xu Z, Chen Z, Song Q, Song Z, Yan G, Mahmoud AM, He Y, Layden BT, Chen J, Ong SG, Xu P, Jiang Y. Estrogen counteracts age-related decline in beige adipogenesis through the NAMPT-regulated ER stress response. Nat Aging. 2024 Jun;4(6):839-853. doi: 10.1038/s43587-024-00633-z. Epub 2024 Jun 10. PubMed PMID: 38858606; PubMed Central PMCID: PMC11829733.

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Yuan Y, Hu R, Park J, Xiong S, Wang Z, Qian Y, Shi Z, Wu R, Han Z, Ong SG, Lin S, Varady KA, Xu P, Berry DC, Shu G, Jiang Y. Macrophage-derived chemokine CCL22 establishes local LN-mediated adaptive thermogenesis and energy expenditure. Sci Adv. 2024 Jun 28;10(26):eadn5229. doi: 10.1126/sciadv.adn5229. Epub 2024 Jun 26. PubMed PMID: 38924414; PubMed Central PMCID: PMC11204298.

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Yuan Y, Shin S, Shi Z, Shu G, Jiang Y. Postnatal Tamoxifen Exposure Induces Long-Lasting Changes to Adipose Tissue in Adult Mice. Mol Biotechnol. 2024 Sep;66(9):2322-2331. doi: 10.1007/s12033-023-00828-6. Epub 2023 Aug 29. PubMed PMID: 37642828; NIHMSID:NIHMS1957647.

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Munoz M, Solis C, McCann M, Park J, Rafael-Clyke K, Chowdhury SAK, Jiang Y, Rosas PC. P21-activated kinase-1 signaling is required to preserve adipose tissue homeostasis and cardiac function. Mol Cell Biochem. 2025 Jan;480(1):249-263. doi: 10.1007/s11010-024-04968-4. Epub 2024 Mar 2. PubMed PMID: 38430300; PubMed Central PMCID: PMC11371416.

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Guo R, Li Y, Song Q, Huang R, Ge X, Nieto N, Jiang Y, Song Z. Increasing cellular NAD(+) protects hepatocytes against palmitate-induced lipotoxicity by preventing PARP-1 inhibition and the mTORC1-p300 pathway activation. Am J Physiol Cell Physiol. 2025 Mar 1;328(3):C776-C790. doi: 10.1152/ajpcell.00946.2024. Epub 2025 Jan 27. PubMed PMID: 39871470; PubMed Central PMCID: PMC12168241.

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Kim YM, Sanborn MA, Vijeth S, Gajwani P, Wang X, Jung D, Valyi-Nagy T, Chakraborty S, Mancinelli G, Toth PT, Phillips EH, Grippo P, Salahudeen AA, Park J, Yeon SY, Ananthanarayanan V, Jiang Y, Lee SS, Valyi-Nagy K, Rehman J. Skeletal muscle endothelial dysfunction through the activin A-PGC1α axis drives progression of cancer cachexia. Nat Cancer. 2025 May 26;. doi: 10.1038/s43018-025-00975-6. [Epub ahead of print] PubMed PMID: 40419762; NIHMSID:NIHMS2088498.

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Li Y, Song Q, Guo R, Qian Y, Jiang Y, Song Z. Glucose metabolism through the hexosamine biosynthetic pathway drives hepatic de novo lipogenesis via promoting N-linked protein glycosylation. Am J Physiol Gastrointest Liver Physiol. 2025 Jun 1;328(6):G746-G759. doi: 10.1152/ajpgi.00056.2025. Epub 2025 May 7. PubMed PMID: 40331866.