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Valanparambil RM, Lai L, Johns MA, Davis-Gardner M, Linderman SL, McPherson TO, Chang A, Akhtar A, Gamarra ELB, Matia H, McCook-Veal AA, Switchenko J, Nasti TH, Green F, Saini M, Wieland A, Pinsky BA, Solis D, Dhodapkar MV, Carlisle J, Ramalingam S, Ahmed R, Suthar MS. BA.5 bivalent booster vaccination enhances neutralization of XBB.1.5, XBB.1.16 and XBB.1.9 variants in patients with lung cancer. NPJ Vaccines. 2023 Nov 21;8(1):179. doi: 10.1038/s41541-023-00779-8. PubMed PMID: 37990024; PubMed Central PMCID: PMC10663480.
Seong CS, Huang C, Boese AC, Hou Y, Koo J, Mouw JK, Rupji M, Joseph G, Johnston HR, Claussen H, Switchenko JM, Behera M, Churchman M, Kolesar JM, Arnold SM, Kerrigan K, Akerley W, Colman H, Johns MA, Arciero C, Zhou W, Marcus AI, Ramalingam SS, Fu H, Gilbert-Ross M. Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis. bioRxiv. 2023 Jan 27;. doi: 10.1101/2023.01.26.525772. PubMed PMID: 36747658; PubMed Central PMCID: PMC9900931.
Valanparambil RM, Carlisle J, Linderman SL, Akthar A, Millett RL, Lai L, Chang A, McCook-Veal AA, Switchenko J, Nasti TH, Saini M, Wieland A, Manning KE, Ellis M, Moore KM, Foster SL, Floyd K, Davis-Gardner ME, Edara VV, Patel M, Steur C, Nooka AK, Green F, Johns MA, O'Brein F, Shanmugasundaram U, Zarnitsyna VI, Ahmed H, Nyhoff LE, Mantus G, Garett M, Edupuganti S, Behra M, Antia R, Wrammert J, Suthar MS, Dhodapkar MV, Ramalingam S, Ahmed R. Antibody Response to COVID-19 mRNA Vaccine in Patients With Lung Cancer After Primary Immunization and Booster: Reactivity to the SARS-CoV-2 WT Virus and Omicron Variant. J Clin Oncol. 2022 Nov 20;40(33):3808-3816. doi: 10.1200/JCO.21.02986. Epub 2022 Jun 27. PubMed PMID: 35759727; PubMed Central PMCID: PMC9671759.
Valanparambil R, Carlisle J, Linderman S, Akthar A, Millett RL, Lai L, Chang A, McCook A, Switchenko J, Nasti T, Saini M, Andreas Wieland AW, Manning K, Ellis M, Moore K, Foster S, Floyd K, Davis-Gardner M, Viswanadh Edara V, Patel M, Steur C, Nooka A, Green F, Johns M, O Brein F, Shanmugasundaram U, Zarnitsyna V, Ahmed H, Nyhoff L, Mantus G, Garett M, Edupuganti S, Behra M, Antia R, Wrammert J, Suthar M, Dhodapkar M, Ramalingam S, Ahmed R. Antibody response to SARS-CoV-2 mRNA vaccine in lung cancer patients: Reactivity to vaccine antigen and variants of concern. medRxiv. 2022 Jan 23;. doi: 10.1101/2022.01.03.22268599. PubMed PMID: 35018383; PubMed Central PMCID: PMC8750706.
Ivanov AA, Revennaugh B, Rusnak L, Gonzalez-Pecchi V, Mo X, Johns MA, Du Y, Cooper LAD, Moreno CS, Khuri FR, Fu H. The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery. Bioinformatics. 2018 Apr 1;34(7):1183-1191. doi: 10.1093/bioinformatics/btx743. PubMed PMID: 29186335; PubMed Central PMCID: PMC6030952.
Ivanov AA, Gonzalez-Pecchi V, Khuri LF, Niu Q, Wang Y, Xu Y, Bai Y, Mo X, Prochownik EV, Johns MA, Du Y, Khuri FR, Fu H. OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc. Oncogene. 2017 Oct 19;36(42):5852-5860. doi: 10.1038/onc.2017.180. Epub 2017 Jun 19. PubMed PMID: 28628118; PubMed Central PMCID: PMC5648601.
Li Z, Ivanov AA, Su R, Gonzalez-Pecchi V, Qi Q, Liu S, Webber P, McMillan E, Rusnak L, Pham C, Chen X, Mo X, Revennaugh B, Zhou W, Marcus A, Harati S, Chen X, Johns MA, White MA, Moreno CS, Cooper LAD, Du Y, Khuri FR, Fu H. Corrigendum: The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nat Commun. 2017 Apr 18;8:15350. doi: 10.1038/ncomms15350. PubMed PMID: 28416792; PubMed Central PMCID: PMC5399281.
Li Z, Ivanov AA, Su R, Gonzalez-Pecchi V, Qi Q, Liu S, Webber P, McMillan E, Rusnak L, Pham C, Chen X, Mo X, Revennaugh B, Zhou W, Marcus A, Harati S, Chen X, Johns MA, White MA, Moreno C, Cooper LA, Du Y, Khuri FR, Fu H. The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nat Commun. 2017 Feb 16;8:14356. doi: 10.1038/ncomms14356. PubMed PMID: 28205554; PubMed Central PMCID: PMC5316855.
Harati S, Cooper LA, Moran JD, Giuste FO, Du Y, Ivanov AA, Johns MA, Khuri FR, Fu H, Moreno CS. MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development. PLoS One. 2017;12(1):e0170339. doi: 10.1371/journal.pone.0170339. eCollection 2017. PubMed PMID: 28118365; PubMed Central PMCID: PMC5261804.
Mo X, Qi Q, Ivanov AA, Niu Q, Luo Y, Havel J, Goetze R, Bell S, Moreno CS, Cooper LA, Johns MA, Khuri FR, Du Y, Fu H. AKT1, LKB1, and YAP1 Revealed as MYC Interactors with NanoLuc-Based Protein-Fragment Complementation Assay. Mol Pharmacol. 2017 Apr;91(4):339-347. doi: 10.1124/mol.116.107623. Epub 2017 Jan 13. PubMed PMID: 28087810; PubMed Central PMCID: PMC5363710.
Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JSK, Kales SC, Mott BT, Rai G, Jansen DJ, Henderson MJ, Urban DJ, Hall MD, Simeonov A, Maloney DJ, Johns MA, Fu H, Jadhav A, Vertino PM, Yan Q, Cheng X. Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chem Biol. 2016 Jul 21;23(7):769-781. doi: 10.1016/j.chembiol.2016.06.006. Epub 2016 Jul 14. PubMed PMID: 27427228; PubMed Central PMCID: PMC4958579.
Cancer Target Discovery and Development Network. Transforming Big Data into Cancer-Relevant Insight: An Initial, Multi-Tier Approach to Assess Reproducibility and Relevance. Mol Cancer Res. 2016 Aug;14(8):675-82. doi: 10.1158/1541-7786.MCR-16-0090. Epub 2016 Jul 11. PubMed PMID: 27401613; PubMed Central PMCID: PMC4987219.
Horton JR, Engstrom A, Zoeller EL, Liu X, Shanks JR, Zhang X, Johns MA, Vertino PM, Fu H, Cheng X. Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases. J Biol Chem. 2016 Feb 5;291(6):2631-46. doi: 10.1074/jbc.M115.698449. Epub 2015 Dec 8. PubMed PMID: 26645689; PubMed Central PMCID: PMC4742734.
Johns MA, Meyerkord-Belton CL, Du Y, Fu H. The Emory Chemical Biology Discovery Center: leveraging academic innovation to advance novel targets through HTS and beyond. Comb Chem High Throughput Screen. 2014 Mar;17(3):290-6. doi: 10.2174/1386207317666140109125415. PubMed PMID: 24409950.
Findlay B, Johns MA. The International Chemical Biology Society's global mission crystallizes in Kyoto. ACS Chem Biol. 2014 Jan 17;9(1):21-7. doi: 10.1021/cb400938n. PubMed PMID: 24432753.
Johns MA. ICBS2012 catalyzes robust response from global chemical biology community. ACS Chem Biol. 2013 Jan 18;8(1):12-8. doi: 10.1021/cb3007049. Epub 2012 Dec 28. PubMed PMID: 23273421.
Johns M, Russ A, Fu H. Current Drug Targets and the Druggable Genome. In: Fu H, editor. Chemical Genomics [Internet] 1 ed. Cambridge University Press; 2012-06. Chapter Chapter 23; 320-332p. Available from: https://www.cambridge.org/core/product/identifier/CBO9781139021500A034/type/book_part.
Johns MA. The international chemical biology community synthesizes a new society. ACS Chem Biol. 2012 Jan 20;7(1):14-9. doi: 10.1021/cb200507f. PubMed PMID: 22260495.
Johns Margaret Ann, Moldover Brian, Offord James David, inventors. alpha-2/delta gene. US US 7262052 B1. 2007 August.
Johns Margaret Ann, Tafuri Sherrie Rae, Wang Minghan, inventors. Gene encoding abc-1 paralogs and the polypeptides derived therefrom. US US 2004/0048250 A1. 2004 March.
Carter MG, Johns MA, Zeng X, Zhou L, Zink MC, Mankowski JL, Donovan DM, Baylin SB. Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome. Hum Mol Genet. 2000 Feb 12;9(3):413-9. doi: 10.1093/hmg/9.3.413. PubMed PMID: 10655551.
Fujii H, Biel MA, Zhou W, Weitzman SA, Baylin SB, Gabrielson E. Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer. Oncogene. 1998 Apr 23;16(16):2159-64. doi: 10.1038/sj.onc.1201976. PubMed PMID: 9572497.
Chen H, Biel MA, Borges MW, Thiagalingam A, Nelkin BD, Baylin SB, Ball DW. Tissue-specific expression of human achaete-scute homologue-1 in neuroendocrine tumors: transcriptional regulation by dual inhibitory regions. Cell Growth Differ. 1997 Jun;8(6):677-86. PubMed PMID: 9186001.
Issa JP, Zehnbauer BA, Kaufmann SH, Biel MA, Baylin SB. HIC1 hypermethylation is a late event in hematopoietic neoplasms. Cancer Res. 1997 May 1;57(9):1678-81. PubMed PMID: 9135007.
Wales MM, Biel MA, el Deiry W, Nelkin BD, Issa JP, Cavenee WK, Kuerbitz SJ, Baylin SB. p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3. Nat Med. 1995 Jun;1(6):570-7. doi: 10.1038/nm0695-570. PubMed PMID: 7585125.
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