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Aksenov NA, Aksenov AV, Kirilov NK, Arutiunov NA, Aksenov DA, Maslivetc V, Zhao Z, Du L, Rubin M, Kornienko A. Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity. Org Biomol Chem. 2020 Sep 14;18(34):6651-6664. doi: 10.1039/d0ob01007c. Epub 2020 Aug 19. PubMed PMID: 32813002; PubMed Central PMCID: PMC7857362.
Eyong KO, Ketsemen HL, Zhao Z, Du L, Mathieu V, Kornienko A, Hull KG, Folefoc GN, Baskaran S, Romo D. Antiproliferative activity of naphthoquinones and indane carboxylic acids from lapachol against a panel of human cancer cell lines. Medicinal Chemistry Research. 2020 April; 29:1058.
Zhao Z, Shelton SD, Oviedo A, Baker AL, Bryant CP, Omidvarnia S, Du L. The PLAGL2/MYCN/miR-506-3p interplay regulates neuroblastoma cell fate and associates with neuroblastoma progression. J Exp Clin Cancer Res. 2020 Feb 22;39(1):41. doi: 10.1186/s13046-020-1531-2. PubMed PMID: 32087738; PubMed Central PMCID: PMC7036248.
Kosti A, Du L, Shivram H, Qiao M, Burns S, Garcia JG, Pertsemlidis A, Iyer VR, Kokovay E, Penalva LOF. ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State. Mol Cancer Res. 2020 Jan;18(1):68-78. doi: 10.1158/1541-7786.MCR-19-0187. Epub 2019 Oct 17. PubMed PMID: 31624087; PubMed Central PMCID: PMC6942226.
Aksenov AV, Aksenov DA, Arutiunov NA, Aksenov NA, Aleksandrova EV, Zhao Z, Du L, Kornienko A, Rubin M. Synthesis of Spiro[indole-3,5'-isoxazoles] with Anticancer Activity via a Formal [4 + 1]-Spirocyclization of Nitroalkenes to Indoles. J Org Chem. 2019 Jun 7;84(11):7123-7137. doi: 10.1021/acs.joc.9b00808. Epub 2019 May 22. PubMed PMID: 31070030.
Zhao Z, Partridge V, Sousares M, Shelton SD, Holland CL, Pertsemlidis A, Du L. microRNA-2110 functions as an onco-suppressor in neuroblastoma by directly targeting Tsukushi. PLoS One. 2018;13(12):e0208777. doi: 10.1371/journal.pone.0208777. eCollection 2018. PubMed PMID: 30550571; PubMed Central PMCID: PMC6294380.
Du L, Zhao Z, Suraokar M, Shelton SS, Ma X, Hsiao TH, Minna JD, Wistuba I, Pertsemlidis A. LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer. Oncotarget. 2018 Jul 3;9(51):29601-29618. doi: 10.18632/oncotarget.25642. eCollection 2018 Jul 3. PubMed PMID: 30038707; PubMed Central PMCID: PMC6049873.
Yu X, Zhang Y, Cavazos D, Ma X, Zhao Z, Du L, Pertsemlidis A. miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer. Cell Death Dis. 2018 Feb 7;9(2):193. doi: 10.1038/s41419-017-0219-9. PubMed PMID: 29416000; PubMed Central PMCID: PMC5833354.
Rastogi SK, Zhao Z, Barrett SL, Shelton SD, Zafferani M, Anderson HE, Blumenthal MO, Jones LR, Wang L, Li X, Streu CN, Du L, Brittain WJ. Photoresponsive azo-combretastatin A-4 analogues. Eur J Med Chem. 2018 Jan 1;143:1-7. doi: 10.1016/j.ejmech.2017.11.012. Epub 2017 Nov 10. PubMed PMID: 29172077.
Sousares M, Partridge V, Weigum S, Du L. MicroRNAs in neuroblastoma differentiation and differentiation therapy. Adv Mod Oncol Res. 2017 October; 3(5):213-222. doi: 10.18282/amor.v3.i5.233.
Li LY, Ma RL, Du L, Wu AS. Ozonated autohemotherapy modulates the serum levels of inflammatory cytokines in gouty patients. Open Access Rheumatol. 2017;9:159-165. doi: 10.2147/OARRR.S119749. eCollection 2017. PubMed PMID: 28860878; PubMed Central PMCID: PMC5565251.
Partridge V, Sousares M, Zhao Z, Du L. Current Understanding on the Role of Cell Cycle Regulators in Neuroblastoma Cell Differentiation. Med One. 2017 June; 2:e170010. doi: 10.20900/mo.20170010.
Zhao Z, Ma X, Shelton SD, Sung DC, Li M, Hernandez D, Zhang M, Losiewicz MD, Chen Y, Pertsemlidis A, Yu X, Liu Y, Du L. A combined gene expression and functional study reveals the crosstalk between N-Myc and differentiation-inducing microRNAs in neuroblastoma cells. Oncotarget. 2016 Nov 29;7(48):79372-79387. doi: 10.18632/oncotarget.12676. PubMed PMID: 27764804; PubMed Central PMCID: PMC5346721.
Borkowski R, Du L, Zhao Z, McMillan E, Kosti A, Yang CR, Suraokar M, Wistuba II, Gazdar AF, Minna JD, White MA, Pertsemlidis A. Genetic mutation of p53 and suppression of the miR-17∼92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D Signaling. Cancer Res. 2015 Feb 15;75(4):666-75. doi: 10.1158/0008-5472.CAN-14-1329. Epub 2014 Dec 17. PubMed PMID: 25519225; PubMed Central PMCID: PMC4333022.
Zhao Z, Ma X, Sung D, Li M, Kosti A, Lin G, Chen Y, Pertsemlidis A, Hsiao TH, Du L. microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest. RNA Biol. 2015;12(5):538-54. doi: 10.1080/15476286.2015.1023495. PubMed PMID: 25760387; PubMed Central PMCID: PMC4615578.
Du L, Zhao Z, Ma X, Hsiao TH, Chen Y, Young E, Suraokar M, Wistuba I, Minna JD, Pertsemlidis A. miR-93-directed downregulation of DAB2 defines a novel oncogenic pathway in lung cancer. Oncogene. 2014 Aug 21;33(34):4307-15. doi: 10.1038/onc.2013.381. Epub 2013 Sep 16. PubMed PMID: 24037530; PubMed Central PMCID: PMC4281941.
Zhao Z, Ma X, Hsiao TH, Lin G, Kosti A, Yu X, Suresh U, Chen Y, Tomlinson GE, Pertsemlidis A, Du L. A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation. Oncotarget. 2014 May 15;5(9):2499-512. doi: 10.18632/oncotarget.1703. PubMed PMID: 24811707; PubMed Central PMCID: PMC4058022.
Du L, Borkowski R, Zhao Z, Ma X, Yu X, Xie XJ, Pertsemlidis A. A high-throughput screen identifies miRNA inhibitors regulating lung cancer cell survival and response to paclitaxel. RNA Biol. 2013 Nov;10(11):1700-13. doi: 10.4161/rna.26541. Epub 2013 Sep 30. PubMed PMID: 24157646; PubMed Central PMCID: PMC3907480.
Du L, Pertsemlidis A. microRNA regulation of cell viability and drug sensitivity in lung cancer. Expert Opin Biol Ther. 2012 Sep;12(9):1221-39. doi: 10.1517/14712598.2012.697149. Epub 2012 Jun 26. Review. PubMed PMID: 22731874.
Du L, Subauste MC, DeSevo C, Zhao Z, Baker M, Borkowski R, Schageman JJ, Greer R, Yang CR, Suraokar M, Wistuba II, Gazdar AF, Minna JD, Pertsemlidis A. miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. PLoS One. 2012;7(6):e39167. doi: 10.1371/journal.pone.0039167. Epub 2012 Jun 18. PubMed PMID: 22723956; PubMed Central PMCID: PMC3377607.
Nikolic D, Calderon L, Du L, Post SR. SR-A ligand and M-CSF dynamically regulate SR-A expression and function in primary macrophages via p38 MAPK activation. BMC Immunol. 2011 Jul 7;12:37. doi: 10.1186/1471-2172-12-37. PubMed PMID: 21736734; PubMed Central PMCID: PMC3141791.
Du L, Pertsemlidis A. Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation. J Mol Cell Biol. 2011 Jun;3(3):176-80. doi: 10.1093/jmcb/mjq058. Epub 2011 Jan 28. Review. PubMed PMID: 21278200; PubMed Central PMCID: PMC3104012.
Subauste MC, Ventura-Holman T, Lu D, Du L, Sansom OJ, Maher JF. Fem1b antigen in the stool of ApcMin mice as a biomarker of early Wnt signaling activation in intestinal neoplasia. Cancer Epidemiol. 2011 Feb;35(1):97-100. doi: 10.1016/j.canep.2010.09.007. Epub 2010 Oct 16. PubMed PMID: 20952268.
Du L, Schageman JJ, Irnov, Girard L, Hammond SM, Minna JD, Gazdar AF, Pertsemlidis A. MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs. J Exp Clin Cancer Res. 2010 Jun 17;29:75. doi: 10.1186/1756-9966-29-75. PubMed PMID: 20624269; PubMed Central PMCID: PMC2907339.
Du L, Pertsemlidis A. microRNAs and lung cancer: tumors and 22-mers. Cancer Metastasis Rev. 2010 Mar;29(1):109-22. doi: 10.1007/s10555-010-9204-9. Review. PubMed PMID: 20130964; PubMed Central PMCID: PMC2884965.
Subauste MC, Sansom OJ, Porecha N, Raich N, Du L, Maher JF. Fem1b, a proapoptotic protein, mediates proteasome inhibitor-induced apoptosis of human colon cancer cells. Mol Carcinog. 2010 Feb;49(2):105-13. doi: 10.1002/mc.20594. PubMed PMID: 19908242.
Subauste MC, Ventura-Holman T, Du L, Subauste JS, Chan SL, Yu VC, Maher JF. RACK1 downregulates levels of the pro-apoptotic protein Fem1b in apoptosis-resistant colon cancer cells. Cancer Biol Ther. 2009 Dec;8(23):2297-305. doi: 10.4161/cbt.8.23.10262. Epub 2009 Dec 7. PubMed PMID: 19855191.
Gibbons DL, Lin W, Creighton CJ, Rizvi ZH, Gregory PA, Goodall GJ, Thilaganathan N, Du L, Zhang Y, Pertsemlidis A, Kurie JM. Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev. 2009 Sep 15;23(18):2140-51. doi: 10.1101/gad.1820209. PubMed PMID: 19759262; PubMed Central PMCID: PMC2751985.
Du L, Schageman JJ, Subauste MC, Saber B, Hammond SM, Prudkin L, Wistuba II, Ji L, Roth JA, Minna JD, Pertsemlidis A. miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1. Mol Cancer Res. 2009 Aug;7(8):1234-43. doi: 10.1158/1541-7786.MCR-08-0507. Epub 2009 Aug 11. PubMed PMID: 19671678; PubMed Central PMCID: PMC2741087.
Du L, Post SR. Macrophage colony-stimulating factor differentially regulates low density lipoprotein and transferrin receptors. J Lipid Res. 2004 Sep;45(9):1733-40. doi: 10.1194/jlr.M400140-JLR200. Epub 2004 Jun 21. PubMed PMID: 15210846.
Du L, Cheng W, Shi K, Jin H. Effect of selenium on the immune responses in normal-immune and immune suppressed mice. J Shanghai 2nd Med Univ. 2000; 20(1):29-31.
Du L, Cheng W, Shi K, Gao M. Toxic effects of selenium on normal-immune and immune-suppressed mice. Shanghai Trace Elements. 2000; 1(3):18-21.
Du L, Cheng W. Selenium and Immune Responses. Foreign Med Sci (Pub Health). 1999; 26(2):91-94.
Du L, Cheng W. Clinical use of selenium in parenteral nutrition. Foreign Med Sci (Medical Geology). 1998; 19(1):4-8.
Tian M, Ye K, Du L, Li Y. Assay of hemoagglutinin inhabitation antibody to hemorrhaghic fever virus. Shanghai J Med Lab Sci. 1994; 9(1):40-41.
Ye K, Du L, Tian M, Zhou L, Li Y, Xu Z. An investigation on wild animal reservoir infected with epidemic hemorraghic fever. Chinese J Pub Health. 1993; 12(6):352-354.
Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity. Organic & biomolecular chemistry. . NIHMSID: NIHMS1667602.
Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity. Organic & biomolecular chemistry. . NIHMSID: NIHMS1669448.
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