My Bibliography

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Wang C, Pan Y, Dong R, Zhou W, Meng X, Kang X, Nistala R, Hammer RD, Li L, Kang X. Longitudinal localization of leukaemic stem cells between the metaphysis and central marrow governs their behaviour. Nat Cell Biol. 2026 May;28(5):890-902. doi: 10.1038/s41556-026-01939-3. Epub 2026 Apr 24. PubMed PMID: 42032313; PubMed Central PMCID: PMC13179134.

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Wang J, Zhang H, Augenreich M, Martinez-Lemus A L, Liu Z, Kang X, Lu B, Chang HM, Yeh ETH, Cata J, Rangaraju S, Wulff H, Li DP. Microglia-Mediated Synaptic Dysfunction Contributes to Chemotherapy-Related Cognitive Impairment. J Neurochem. 2025 Mar;169(3):e70024. doi: 10.1111/jnc.70024. PubMed PMID: 40019120; PubMed Central PMCID: PMC11927766.

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Chen X, Li D, Su Q, Ling X, Ding S, Xu R, Liu Z, Qin Y, Zhang J, Yang Z, Kang X, Qi Y, Wu H. MicroRNA-145-5p inhibits the tumorigenesis of breast cancer through SENP2-regulated ubiquitination of ERK2. Cell Mol Life Sci. 2024 Nov 23;81(1):461. doi: 10.1007/s00018-024-05505-8. PubMed PMID: 39578257; PubMed Central PMCID: PMC11584840.

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Urban-Gedamke E, Conkling M, Goodman C, Han X, Pomponi SA. Novel use of a - 20°C cryoprotectant yields high viability and improved aggregation of marine sponge cells. In Vitro Cell Dev Biol Anim. 2025 May;61(5):511-514. doi: 10.1007/s11626-024-00959-3. Epub 2024 Aug 2. PubMed PMID: 39093367.

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Pan Y, Wang C, Zhou W, Shi Y, Meng X, Muhammad Y, Hammer RD, Jia B, Zheng H, Li DP, Liu Z, Hildebrandt G, Kang X. Inhibiting AGTR1 reduces AML burden and protects the heart from cardiotoxicity in mouse models. Sci Transl Med. 2024 Jun 19;16(752):eadl5931. doi: 10.1126/scitranslmed.adl5931. Epub 2024 Jun 19. PubMed PMID: 38896605; PubMed Central PMCID: PMC11250918.

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Zhou W, Wang C, Shi Y, Pan Y, Meng X, Kang X, Han X. Novel cryopreservation medium for enhanced stability of T cells at −80°C. Frontiers in Hematology. 2024 June; 3. doi: 10.1007/s00018-024-05505-8.

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Pan Y, Kang X. Limited dsRNA editing impedes leukemia stem cells. Trends Cancer. 2024 Apr;10(4):280-282. doi: 10.1016/j.trecan.2024.02.005. Epub 2024 Mar 7. PubMed PMID: 38458943; PubMed Central PMCID: PMC11047023.

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Xu X, Yu Y, Zhang W, Ma W, He C, Qiu G, Wang X, Liu Q, Zhao M, Xie J, Tao F, Perry JM, Liu Q, Rao S, Kang X, Zhao M, Jiang L. SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming. Nat Cell Biol. 2024 Mar;26(3):464-477. doi: 10.1038/s41556-024-01349-3. Epub 2024 Feb 6. PubMed PMID: 38321204.

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Sheng ZF, Zhang H, Phaup JG, Zheng P, Kang X, Liu Z, Chang HM, Yeh ETH, Johnson AK, Pan HL, Li DP. Corticotropin-releasing hormone neurons in the central nucleus of amygdala are required for chronic stress-induced hypertension. Cardiovasc Res. 2023 Jul 6;119(8):1751-1762. doi: 10.1093/cvr/cvad056. PubMed PMID: 37041718; PubMed Central PMCID: PMC10325697.

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Zhang H, Zhou JJ, Shao JY, Sheng ZF, Wang J, Zheng P, Kang X, Liu Z, Cheng ZJ, Kline DD, Li DP. Hypothalamic Corticotropin-Releasing Hormone Contributes to Hypertension in Spontaneously Hypertensive Rats. J Neurosci. 2023 Jun 14;43(24):4513-4524. doi: 10.1523/JNEUROSCI.2343-22.2023. Epub 2023 May 9. PubMed PMID: 37160364; PubMed Central PMCID: PMC10278672.

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Wang C, Nistala R, Cao M, Pan Y, Behrens M, Doll D, Hammer RD, Nistala P, Chang HM, Yeh ETH, Kang X. Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells. Cell Rep. 2023 Feb 28;42(2):112105. doi: 10.1016/j.celrep.2023.112105. Epub 2023 Feb 17. PubMed PMID: 36807138; PubMed Central PMCID: PMC10432577.

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Wang C, Nistala R, Cao M, Li DP, Pan Y, Golzy M, Cui Y, Liu Z, Kang X. Repair of Limb Ischemia Is Dependent on Hematopoietic Stem Cell Specific-SHP-1 Regulation of TGF-β1. Arterioscler Thromb Vasc Biol. 2023 Jan;43(1):92-108. doi: 10.1161/ATVBAHA.122.318205. Epub 2022 Nov 22. PubMed PMID: 36412197; PubMed Central PMCID: PMC10037747.

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Li C, Wu B, Li Y, Liu Y, Wang J, Xie J, Xu X, Tian X, Ye Z, Guan J, Chen J, Xie S, Zhang B, Cai B, Wang Q, Yu H, Lan T, Man CH, Kang X, Qian P, Perry JM, He A, Jiang L, Zhao M. Loss of sphingosine kinase 2 promotes the expansion of hematopoietic stem cells by improving their metabolic fitness. Blood. 2022 Oct 13;140(15):1686-1701. doi: 10.1182/blood.2022016112. PubMed PMID: 35881840.

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Zhang H, Sheng ZF, Wang J, Zheng P, Kang X, Chang HM, Yeh ETH, Li DP. Signaling pathways involved in NMDA-induced suppression of M-channels in corticotropin-releasing hormone neurons in central amygdala. J Neurochem. 2022 Jun;161(6):478-491. doi: 10.1111/jnc.15647. Epub 2022 May 30. PubMed PMID: 35583089; PubMed Central PMCID: PMC10210974.

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Cui C, Wang C, Cao M, Kang X. Ca(2+)/calmodulin-dependent Protein Kinases in Leukemia Development. J Cell Immunol. 2021;3(3):144-150. doi: 10.33696/immunology.3.091. PubMed PMID: 34263253; PubMed Central PMCID: PMC8276974.

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Hao F, Sholy C, Wang C, Cao M, Kang X. The Role of T Cell Immunotherapy in Acute Myeloid Leukemia. Cells. 2021 Dec 1;10(12). doi: 10.3390/cells10123376. Review. PubMed PMID: 34943884; PubMed Central PMCID: PMC8699747.

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Hao F, Wang C, Sholy C, Cao M, Kang X. Strategy for Leukemia Treatment Targeting SHP-1,2 and SHIP. Front Cell Dev Biol. 2021;9:730400. doi: 10.3389/fcell.2021.730400. eCollection 2021. Review. PubMed PMID: 34490276; PubMed Central PMCID: PMC8417302.

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Zhang LS, Kang X, Lu J, Zhang Y, Wu X, Wu G, Zheng J, Tuladhar R, Shi H, Wang Q, Morlock L, Yao H, Huang LJ, Maire P, Kim J, Williams N, Xu J, Chen C, Zhang CC, Lum L. Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9. EBioMedicine. 2019 Jan;39:145-158. doi: 10.1016/j.ebiom.2018.11.039. Epub 2018 Dec 6. PubMed PMID: 30528456; PubMed Central PMCID: PMC6354558.

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Jiang L, Han X, Wang J, Wang C, Sun X, Xie J, Wu G, Phan H, Liu Z, Yeh ETH, Zhang C, Zhao M, Kang X. Correction: SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling. J Exp Med. 2018 Aug 6;215(8):2227. doi: 10.1084/jem.2017147706252018c. Epub 2018 Jul 13. PubMed PMID: 30006358; PubMed Central PMCID: PMC6080911.

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Jiang L, Han X, Wang J, Wang C, Sun X, Xie J, Wu G, Phan H, Liu Z, Yeh ETH, Zhang C, Zhao M, Kang X. SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling. J Exp Med. 2018 May 7;215(5):1337-1347. doi: 10.1084/jem.20171477. Epub 2018 Apr 18. PubMed PMID: 29669741; PubMed Central PMCID: PMC5940262.

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Kang X, Cui C, Wang C, Wu G, Chen H, Lu Z, Chen X, Wang L, Huang J, Geng H, Zhao M, Chen Z, Müschen M, Wang HY, Zhang CC. CAMKs support development of acute myeloid leukemia. J Hematol Oncol. 2018 Feb 27;11(1):30. doi: 10.1186/s13045-018-0574-8. PubMed PMID: 29482582; PubMed Central PMCID: PMC5828341.

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Kang X, Kim J, Deng M, John S, Chen H, Wu G, Phan H, Zhang CC. Inhibitory leukocyte immunoglobulin-like receptors: Immune checkpoint proteins and tumor sustaining factors. Cell Cycle. 2016;15(1):25-40. doi: 10.1080/15384101.2015.1121324. Review. PubMed PMID: 26636629; PubMed Central PMCID: PMC4825776.

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Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC. Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation. Nat Med. 2017 Jan;23(1):79-90. doi: 10.1038/nm.4252. Epub 2016 Dec 12. PubMed PMID: 27941793; PubMed Central PMCID: PMC6956990.

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Dong B, Gao Y, Kang X, Gao H, Zhang J, Guo H, You MJ, Xue W, Cheng J, Huang Y. SENP1 promotes proliferation of clear cell renal cell carcinoma through activation of glycolysis. Oncotarget. 2016 Dec 6;7(49):80435-80449. doi: 10.18632/oncotarget.12606. PubMed PMID: 27741516; PubMed Central PMCID: PMC5348332.

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Xu F, Gao Y, Wang Y, Pan J, Sha J, Shao X, Kang X, Qin J, You MJ, Huang Y, Dong B, Xue W. Decreased TSPAN1 promotes prostate cancer progression and is a marker for early biochemical recurrence after radical prostatectomy. Oncotarget. 2016 Sep 27;7(39):63294-63305. doi: 10.18632/oncotarget.11448. PubMed PMID: 27556508; PubMed Central PMCID: PMC5325364.

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Zhang F, Zheng J, Kang X, Deng M, Lu Z, Kim J, Zhang C. Inhibitory leukocyte immunoglobulin-like receptors in cancer development. Sci China Life Sci. 2015 Dec;58(12):1216-25. doi: 10.1007/s11427-015-4925-1. Epub 2015 Nov 14. Review. PubMed PMID: 26566804.

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Kang X, Lu Z, Cui C, Deng M, Fan Y, Dong B, Han X, Xie F, Tyner JW, Coligan JE, Collins RH, Xiao X, You MJ, Zhang CC. The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development. Nat Cell Biol. 2015 May;17(5):665-77. doi: 10.1038/ncb3158. Epub 2015 Apr 27. PubMed PMID: 25915125; PubMed Central PMCID: PMC4417000.

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Zheng J, Lu Z, Kocabas F, Böttcher RT, Costell M, Kang X, Liu X, Deberardinis RJ, Wang Q, Chen GQ, Sadek H, Zhang CC. Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow. Blood. 2014 Feb 13;123(7):992-1001. doi: 10.1182/blood-2013-04-498469. Epub 2014 Jan 2. PubMed PMID: 24385538; PubMed Central PMCID: PMC3924932.

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Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang C, Huynh H, Kang X, Silvany R, Wan X, Ye J, Cantó AP, Chen SH, Wang HY, Ward ES, Zhang CC. Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development. Nature. 2012 May 30;485(7400):656-60. doi: 10.1038/nature11095. PubMed PMID: 22660330; PubMed Central PMCID: PMC3367397.

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Yan S, Sun X, Xiang B, Cang H, Kang X, Chen Y, Li H, Shi G, Yeh ET, Wang B, Wang X, Yi J. Redox regulation of the stability of the SUMO protease SENP3 via interactions with CHIP and Hsp90. EMBO J. 2010 Nov 17;29(22):3773-86. doi: 10.1038/emboj.2010.245. Epub 2010 Oct 5. PubMed PMID: 20924358; PubMed Central PMCID: PMC2989103.

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Xu Y, Zuo Y, Zhang H, Kang X, Yue F, Yi Z, Liu M, Yeh ET, Chen G, Cheng J. Induction of SENP1 in endothelial cells contributes to hypoxia-driven VEGF expression and angiogenesis. J Biol Chem. 2010 Nov 19;285(47):36682-8. doi: 10.1074/jbc.M110.164236. Epub 2010 Sep 14. PubMed PMID: 20841360; PubMed Central PMCID: PMC2978597.

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Kang X, Li J, Zou Y, Yi J, Zhang H, Cao M, Yeh ET, Cheng J. PIASy stimulates HIF1α SUMOylation and negatively regulates HIF1α activity in response to hypoxia. Oncogene. 2010 Oct 14;29(41):5568-78. doi: 10.1038/onc.2010.297. Epub 2010 Jul 26. PubMed PMID: 20661221.

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Kang X, Qi Y, Zuo Y, Wang Q, Zou Y, Schwartz RJ, Cheng J, Yeh ET. SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Mol Cell. 2010 Apr 23;38(2):191-201. doi: 10.1016/j.molcel.2010.03.005. PubMed PMID: 20417598; PubMed Central PMCID: PMC2879644.

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Cheng J, Kang X, Zhang S, Yeh ET. SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell. 2007 Nov 2;131(3):584-95. doi: 10.1016/j.cell.2007.08.045. PubMed PMID: 17981124; PubMed Central PMCID: PMC2128732.

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Yang J, Li H, Chen YY, Wang XJ, Shi GY, Hu QS, Kang XL, Lu Y, Tang XM, Guo QS, Yi J. Anthraquinones sensitize tumor cells to arsenic cytotoxicity in vitro and in vivo via reactive oxygen species-mediated dual regulation of apoptosis. Free Radic Biol Med. 2004 Dec 15;37(12):2027-41. doi: 10.1016/j.freeradbiomed.2004.09.016. PubMed PMID: 15544921.

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Novel cryopreservation medium for enhanced stability of T cells at −80°C. Frontiers in hematology. . NIHMSID: NIHMS2206131.doi: 10.3389/frhem.2024.1346627.