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Lee DJ, inventor. Treatment of Autoimmune Diseases and Cancer with Protease Inhibitors. United States patent application PCT International Application No. PCT/US2024/023321. 2024 April.
Chan AA, Tran PT, Lee DJ. Quantitative Aggregation of Microbiome Sequencing Data Provides Insights into the Associations between the Skin Microbiome and Psoriasis. JID Innov. 2024 Jan;4(1):100249. doi: 10.1016/j.xjidi.2023.100249. eCollection 2024 Jan. PubMed PMID: 38282647; PubMed Central PMCID: PMC10810833.
Li W, Chan AA, Han J, Chlebowski RT, Lee DJ. Alcohol and Smoking Cessation as Potential Modulators for Smoking-Associated Psoriasis Risk in Postmenopausal Women: The Women's Health Initiative. Am J Clin Dermatol. 2023 Mar;24(2):325-332. doi: 10.1007/s40257-022-00750-8. Epub 2023 Jan 20. PubMed PMID: 36662365; PubMed Central PMCID: PMC9968247.
Chan AA, Li H, Li W, Pan K, Yee JK, Chlebowski RT, Lee DJ. Association between baseline insulin resistance and psoriasis incidence: the Women's Health Initiative. Arch Dermatol Res. 2022 Nov;314(9):869-880. doi: 10.1007/s00403-021-02298-9. Epub 2021 Nov 24. PubMed PMID: 34816303; PubMed Central PMCID: PMC9512862.
Ding L, Gosh A, Lee DJ, Emri G, Huss WJ, Bogner PN, Paragh G. Prognostic biomarkers of cutaneous melanoma. Photodermatol Photoimmunol Photomed. 2022 Sep;38(5):418-434. doi: 10.1111/phpp.12770. Epub 2022 Jan 17. Review. PubMed PMID: 34981569.
Umar S, Lullo JJ, Carter MJ, Shitabata PK, Lee DJ. Acne Keloidalis Nuchae is Associated with Cutis Verticis Gyrata. Clin Cosmet Investig Dermatol. 2022;15:1421-1427. doi: 10.2147/CCID.S369243. eCollection 2022. PubMed PMID: 35924256; PubMed Central PMCID: PMC9342927.
Kremenovic M, Chan AA, Feng B, Bäriswyl L, Robatel S, Gruber T, Tang L, Lee DJ, Schenk M. BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma. J Immunother Cancer. 2022 Jun;10(6). doi: 10.1136/jitc-2021-004133. PubMed PMID: 35732347; PubMed Central PMCID: PMC9226922.
Chan AA, Flores EA, Navarrete M, Phan Tran D, Lee DJ, Miller LG. The Effect of Systemic Antibiotics for Suppurative Skin and Soft Tissue Infections on the Skin Microbiome. Open Forum Infect Dis. 2022 May;9(5):ofac141. doi: 10.1093/ofid/ofac141. eCollection 2022 May. PubMed PMID: 35450081; PubMed Central PMCID: PMC9017368.
Chung AW, Kozielski AJ, Qian W, Zhou J, Anselme AC, Chan AA, Pan PY, Lee DJ, Chang JC. Tocilizumab overcomes chemotherapy resistance in mesenchymal stem-like breast cancer by negating autocrine IL-1A induction of IL-6. NPJ Breast Cancer. 2022 Mar 8;8(1):30. doi: 10.1038/s41523-021-00371-0. PubMed PMID: 35260569; PubMed Central PMCID: PMC8904846.
Chung AW, Anand K, Anselme AC, Chan AA, Gupta N, Venta LA, Schwartz MR, Qian W, Xu Y, Zhang L, Kuhn J, Patel T, Rodriguez AA, Belcheva A, Darcourt J, Ensor J, Bernicker E, Pan PY, Chen SH, Lee DJ, Niravath PA, Chang JC. A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer. Sci Transl Med. 2021 Dec 15;13(624):eabj5070. doi: 10.1126/scitranslmed.abj5070. Epub 2021 Dec 15. PubMed PMID: 34910551.
Li W, Le N, Lee DJ, Reuter K. Analysis of psoriasis-related posts on Twitter: An abundance of patient-driven advocacy versus a scarcity of dermatologists. J Am Acad Dermatol. 2021 Dec;85(6):1579-1581. doi: 10.1016/j.jaad.2020.11.004. Epub 2020 Nov 7. PubMed PMID: 33171165.
Chan AA, Noguti J, Yang CT, Feldman SR, Wallace RB, Shadyab AH, Manson JE, Aragaki AK, Chlebowski RT, Lee DJ. Association between menopausal hormone therapy and incidence of psoriasis: a secondary analysis from the Women's Health Initiative randomized clinical trials. Br J Dermatol. 2021 Sep;185(3):669-671. doi: 10.1111/bjd.20410. Epub 2021 Jun 14. PubMed PMID: 33913153.
Li W, Ma JE, Chan AA, Lee DJ, Smogorzewski J. Hidradenitis suppurativa through the lens of YouTube: A cross-sectional analysis. J Am Acad Dermatol. 2021 May;84(5):1398-1399. doi: 10.1016/j.jaad.2020.05.148. Epub 2020 Jun 6. PubMed PMID: 32522514.
Umar S, Lee DJ, Lullo JJ. A Retrospective Cohort Study and Clinical Classification System of Acne Keloidalis Nuchae. J Clin Aesthet Dermatol. 2021 Apr;14(4):E61-E67. Epub 2021 Apr 1. PubMed PMID: 34055191; PubMed Central PMCID: PMC8142833.
Reuter K, Lee D. Perspectives Toward Seeking Treatment Among Patients With Psoriasis: Protocol for a Twitter Content Analysis. JMIR Res Protoc. 2021 Feb 18;10(2):e13731. doi: 10.2196/13731. PubMed PMID: 33599620; PubMed Central PMCID: PMC7932841.
Walters ME, Lee DJ, Yamauchi PS. Increased Trend of Cosmetic Procedures in Patients With Psoriasis Who Attain 75% or Greater Improvement. J Drugs Dermatol. 2020 Aug 1;19(8):698-701. doi: 10.36849/JDD.2020.5104R1. PubMed PMID: 32845593.
Chen YC, Navarrete MS, Wang Y, McClintock NC, Sakurai R, Wang F, Chen KT, Chou TF, Rehan VK, Lee DJ, Diaz B. N-myristoyltransferase-1 is necessary for lysosomal degradation and mTORC1 activation in cancer cells. Sci Rep. 2020 Jul 20;10(1):11952. doi: 10.1038/s41598-020-68615-w. PubMed PMID: 32686708; PubMed Central PMCID: PMC7371688.
Kremenovic M, Rombini N, Chan AA, Gruber T, Bäriswyl L, Lee DJ, Schenk M. Characterization of a Myeloid Activation Signature that Correlates with Survival in Melanoma Patients. Cancers (Basel). 2020 May 31;12(6). doi: 10.3390/cancers12061431. PubMed PMID: 32486450; PubMed Central PMCID: PMC7352688.
Galamgam J, Lee DJ. Treatment of transient acantholytic dermatosis with liquid nitrogen. JAAD Case Rep. 2020 Apr;6(4):341-343. doi: 10.1016/j.jdcr.2020.02.027. eCollection 2020 Apr. PubMed PMID: 32258316; PubMed Central PMCID: PMC7103660.
Pan K, Nelson RA, Wactawski-Wende J, Lee DJ, Manson JE, Aragaki AK, Mortimer JE, Phillips LS, Rohan T, Ho GYF, Saquib N, Shadyab AH, Nassir R, Rhee JJ, Hurria A, Chlebowski RT. Insulin Resistance and Cancer-Specific and All-Cause Mortality in Postmenopausal Women: The Women's Health Initiative. J Natl Cancer Inst. 2020 Feb 1;112(2):170-178. doi: 10.1093/jnci/djz069. PubMed PMID: 31184362; PubMed Central PMCID: PMC7019097.
Adhikary S, Hoskin TL, Stallings-Mann ML, Arshad M, Frost MH, Winham SJ, Peña A, Lee DJ, Murphy LM, Rakoff M, Denison LA, Knutson KL, Radisky DC, Visscher DW, Degnim AC. Cytotoxic T cell depletion with increasing epithelial abnormality in women with benign breast disease. Breast Cancer Res Treat. 2020 Feb;180(1):55-61. doi: 10.1007/s10549-019-05493-5. Epub 2020 Jan 13. PubMed PMID: 31933142; PubMed Central PMCID: PMC7031204.
Reuter K, Lee D. Evaluating patients' perspectives on social media: the importance of clearly reporting data search, cleaning and processing. Br J Dermatol. 2019 Jul;181(1):222. doi: 10.1111/bjd.17868. Epub 2019 Apr 14. PubMed PMID: 30851190; PubMed Central PMCID: PMC6602796.
Chan AA, Noguti J, Pak Y, Qi L, Caan B, Going S, Han J, Chlebowski RT, Lee DJ. Interaction of body mass index or waist-to-hip ratio and sun exposure associated with nonmelanoma skin cancer: A prospective study from the Women's Health Initiative. Cancer. 2019 Apr 1;125(7):1133-1142. doi: 10.1002/cncr.31810. Epub 2018 Dec 11. PubMed PMID: 30548236.
Noguti J, Lee DJ. Association of Microbes with Breast Cancer. Microbiome and Cancer. 2019 February; :123-149. doi: 10.1007/978-3-030-04155-7_7.
Li H, Lee D. Epidemiology and Immunopathogenesis of Psoriasis and Its Comorbidities. Current Dermatology Reports. 2018 December; 7(4):321-329.
Li H, Lee D, Yuen M. Advances in Immune Pathways and Pathogenesis of Atopic Dermatitis. Current Dermatology Reports.. 2018 December; 7(4):330-337.
Kang A, Zhao D, Yeh JJ, Lee DJ. Updates on Immunotherapy for the Treatment of Skin Cancer. Current Dermatology Reports. 2018 November; 7(4):311-320. doi: 10.1007/s13671-018-0246-5.
Linfield RY, Campeau S, Injean P, Gregson A, Kaldas F, Rubin Z, Kim T, Kunz D, Chan A, Lee DJ, Humphries RM, McKinnell JA. Practical methods for effective vancomycin-resistant enterococci (VRE) surveillance: experience in a liver transplant surgical intensive care unit. Infect Control Hosp Epidemiol. 2018 Oct;39(10):1178-1182. doi: 10.1017/ice.2018.178. Epub 2018 Sep 4. PubMed PMID: 30178725.
Kang A, Yuen M, Lee DJ. Nivolumab-induced systemic vasculitis. JAAD Case Rep. 2018 Jul;4(6):606-608. doi: 10.1016/j.jdcr.2018.03.013. eCollection 2018 Jul. PubMed PMID: 30003129; PubMed Central PMCID: PMC6039753.
Noguti J, Chan AA, Bandera B, Brislawn CJ, Protic M, Sim MS, Jansson JK, Bilchik AJ, Lee DJ. Both the intratumoral immune and microbial microenvironment are linked to recurrence in human colon cancer: results from a prospective, multicenter nodal ultrastaging trial. Oncotarget. 2018 May 4;9(34):23564-23576. doi: 10.18632/oncotarget.25276. eCollection 2018 May 4. PubMed PMID: 29805756; PubMed Central PMCID: PMC5955112.
Flaherty DC, Jalas JR, Sim MS, Stojadinovic A, Protic M, Lee DJ, Bilchik AJ. The Negative Impact of Body Mass Index on the Tumor Microenvironment in Colon Cancer: Results of a Prospective Trial. Ann Surg Oncol. 2018 May;25(5):1374-1380. doi: 10.1245/s10434-018-6405-x. Epub 2018 Mar 12. PubMed PMID: 29532344.
Lardone RD, Chan AA, Lee AF, Foshag LJ, Faries MB, Sieling PA, Lee DJ. Mycobacterium bovis Bacillus Calmette-Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function. Front Immunol. 2017;8:965. doi: 10.3389/fimmu.2017.00965. eCollection 2017. PubMed PMID: 28848560; PubMed Central PMCID: PMC5554507.
Yang J, Jones MS, Ramos RI, Chan AA, Lee AF, Foshag LJ, Sieling PA, Faries MB, Lee DJ. Insights into Local Tumor Microenvironment Immune Factors Associated with Regression of Cutaneous Melanoma Metastases by Mycobacterium bovis Bacille Calmette-Guérin. Front Oncol. 2017;7:61. doi: 10.3389/fonc.2017.00061. eCollection 2017. PubMed PMID: 28424760; PubMed Central PMCID: PMC5380679.
Flaherty DC, Lavotshkin S, Jalas JR, Torisu-Itakura H, Kirchoff DD, Sim MS, Lee DJ, Bilchik AJ. Prognostic Utility of Immunoprofiling in Colon Cancer: Results from a Prospective, Multicenter Nodal Ultrastaging Trial. J Am Coll Surg. 2016 Jul;223(1):134-40. doi: 10.1016/j.jamcollsurg.2016.03.003. Epub 2016 Mar 18. PubMed PMID: 27282965.
Chan AA, Bashir M, Rivas MN, Duvall K, Sieling PA, Pieber TR, Vaishampayan PA, Love SM, Lee DJ. Characterization of the microbiome of nipple aspirate fluid of breast cancer survivors. Sci Rep. 2016 Jun 21;6:28061. doi: 10.1038/srep28061. PubMed PMID: 27324944; PubMed Central PMCID: PMC4914981.
Lardone RD, Plaisier SB, Navarrete MS, Shamonki JM, Jalas JR, Sieling PA, Lee DJ. Cross-platform comparison of independent datasets identifies an immune signature associated with improved survival in metastatic melanoma. Oncotarget. 2016 Mar 22;7(12):14415-28. doi: 10.18632/oncotarget.7361. PubMed PMID: 26883106; PubMed Central PMCID: PMC4924725.
King JK, Philips RL, Eriksson AU, Kim PJ, Halder RC, Lee DJ, Singh RR. Langerhans Cells Maintain Local Tissue Tolerance in a Model of Systemic Autoimmune Disease. J Immunol. 2015 Jul 15;195(2):464-76. doi: 10.4049/jimmunol.1402735. Epub 2015 Jun 12. PubMed PMID: 26071559; PubMed Central PMCID: PMC4562401.
Ozao-Choy J, Lee DJ, Faries MB. Melanoma vaccines: mixed past, promising future. Surg Clin North Am. 2014 Oct;94(5):1017-30, viii. doi: 10.1016/j.suc.2014.07.005. Epub 2014 Aug 7. Review. PubMed PMID: 25245965; PubMed Central PMCID: PMC4173123.
Leung AM, Lee AF, Ozao-Choy J, Ramos RI, Hamid O, O'Day SJ, Shin-Sim M, Morton DL, Faries MB, Sieling PA, Lee DJ. Clinical Benefit from Ipilimumab Therapy in Melanoma Patients may be Associated with Serum CTLA4 Levels. Front Oncol. 2014;4:110. doi: 10.3389/fonc.2014.00110. eCollection 2014. Review. PubMed PMID: 24904825; PubMed Central PMCID: PMC4032905.
Schenk M, Fabri M, Krutzik SR, Lee DJ, Vu DM, Sieling PA, Montoya D, Liu PT, Modlin RL. Interleukin-1β triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells. Immunology. 2014 Feb;141(2):174-80. doi: 10.1111/imm.12167. PubMed PMID: 24032597; PubMed Central PMCID: PMC3904238.
Xuan C, Shamonki JM, Chung A, Dinome ML, Chung M, Sieling PA, Lee DJ. Microbial dysbiosis is associated with human breast cancer. PLoS One. 2014;9(1):e83744. doi: 10.1371/journal.pone.0083744. eCollection 2014. PubMed PMID: 24421902; PubMed Central PMCID: PMC3885448.
Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science. 2013 Mar 22;339(6126):1448-53. doi: 10.1126/science.1233665. Epub 2013 Feb 28. PubMed PMID: 23449998; PubMed Central PMCID: PMC3653587.
Chung AW, Sieling PA, Schenk M, Teles RM, Krutzik SR, Hsu DK, Liu FT, Sarno EN, Rea TH, Stenger S, Modlin RL, Lee DJ. Galectin-3 regulates the innate immune response of human monocytes. J Infect Dis. 2013 Mar 15;207(6):947-56. doi: 10.1093/infdis/jis920. Epub 2012 Dec 18. PubMed PMID: 23255567; PubMed Central PMCID: PMC3571442.
Kulkarni RP, Plaisier S, Ra SH, Li X, Lee DJ, Hillman JD, Binder SW. Genetic profiling of BRAF inhibitor-induced keratoacanthomas reveals no induction of MAP kinase pathway expression. J Invest Dermatol. 2013 Mar;133(3):830-833. doi: 10.1038/jid.2012.353. Epub 2012 Sep 27. PubMed PMID: 23014342.
Lee AF, Sieling PA, Lee DJ. Immune correlates of melanoma survival in adoptive cell therapy. Oncoimmunology. 2013 Feb 1;2(2):e22889. doi: 10.4161/onci.22889. PubMed PMID: 23525606; PubMed Central PMCID: PMC3601160.
Cho JS, Guo Y, Ramos RI, Hebroni F, Plaisier SB, Xuan C, Granick JL, Matsushima H, Takashima A, Iwakura Y, Cheung AL, Cheng G, Lee DJ, Simon SI, Miller LS. Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice. PLoS Pathog. 2012;8(11):e1003047. doi: 10.1371/journal.ppat.1003047. Epub 2012 Nov 29. PubMed PMID: 23209417; PubMed Central PMCID: PMC3510260.
Kidner TB, Morton DL, Lee DJ, Hoban M, Foshag LJ, Turner RR, Faries MB. Combined intralesional Bacille Calmette-Guérin (BCG) and topical imiquimod for in-transit melanoma. J Immunother. 2012 Nov-Dec;35(9):716-20. doi: 10.1097/CJI.0b013e31827457bd. PubMed PMID: 23090081; PubMed Central PMCID: PMC3674843.
Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nat Med. 2012 Mar 25;18(4):555-63. doi: 10.1038/nm.2650. PubMed PMID: 22447076; PubMed Central PMCID: PMC3348859.
Worswick S, Pirouz A, Lee DJ. Depigmented macules following autologous bone-marrow transplant. Arch Dermatol. 2011 Dec;147(12):1460-1. doi: 10.1001/archderm.147.12.1460. PubMed PMID: 22184779.
Ochoa MT, Teles R, Haas BE, Zaghi D, Li H, Sarno EN, Rea TH, Modlin RL, Lee DJ. A role for interleukin-5 in promoting increased immunoglobulin M at the site of disease in leprosy. Immunology. 2010 Nov;131(3):405-14. doi: 10.1111/j.1365-2567.2010.03314.x. PubMed PMID: 20561085; PubMed Central PMCID: PMC2996561.
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