My Bibliography

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Yin D, Fox B, Lonetto ML, Etherton MR, Payne DJ, Holmes DJ, Rosenberg M, Ji Y. Identification of antimicrobial targets using a comprehensive genomic approach. Pharmacogenomics. 2004 Jan;5(1):101-13. doi: 10.1517/phgs.5.1.101.25679. PubMed PMID: 14683422.

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Lu Q, Yang YT, Chen CS, Davis M, Byrd JC, Etherton MR, Umar A, Chen CS. Zn2+-chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors. J Med Chem. 2004 Jan 15;47(2):467-74. doi: 10.1021/jm0303655. PubMed PMID: 14711316.

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Helfrich MR, El-Kouedi M, Etherton MR, Keating CD. Partitioning and assembly of metal particles and their bioconjugates in aqueous two-phase systems. Langmuir. 2005 Aug 30;21(18):8478-86. doi: 10.1021/la051220z. PubMed PMID: 16114960.

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Chubykin AA, Atasoy D, Etherton MR, Brose N, Kavalali ET, Gibson JR, Südhof TC. Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2. Neuron. 2007 Jun 21;54(6):919-31. doi: 10.1016/j.neuron.2007.05.029. PubMed PMID: 17582332; PubMed Central PMCID: PMC3738748.

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Tabuchi K, Blundell J, Etherton MR, Hammer RE, Liu X, Powell CM, Südhof TC. A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science. 2007 Oct 5;318(5847):71-6. doi: 10.1126/science.1146221. Epub 2007 Sep 6. PubMed PMID: 17823315; PubMed Central PMCID: PMC3235367.

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Etherton MR, Blaiss CA, Powell CM, Südhof TC. Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17998-8003. doi: 10.1073/pnas.0910297106. Epub 2009 Oct 12. PubMed PMID: 19822762; PubMed Central PMCID: PMC2764944.

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Blundell J, Blaiss CA, Etherton MR, Espinosa F, Tabuchi K, Walz C, Bolliger MF, Südhof TC, Powell CM. Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior. J Neurosci. 2010 Feb 10;30(6):2115-29. doi: 10.1523/JNEUROSCI.4517-09.2010. PubMed PMID: 20147539; PubMed Central PMCID: PMC2824441.

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Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC. Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science. 2010 Sep 24;329(5999):1663-7. doi: 10.1126/science.1195227. Epub 2010 Aug 26. PubMed PMID: 20798282; PubMed Central PMCID: PMC3235365.

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Etherton MR, Tabuchi K, Sharma M, Ko J, Südhof TC. An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus. EMBO J. 2011 Jun 3;30(14):2908-19. doi: 10.1038/emboj.2011.182. PubMed PMID: 21642956; PubMed Central PMCID: PMC3160244.

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Etherton M, Földy C, Sharma M, Tabuchi K, Liu X, Shamloo M, Malenka RC, Südhof TC. Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13764-9. doi: 10.1073/pnas.1111093108. Epub 2011 Aug 1. PubMed PMID: 21808020; PubMed Central PMCID: PMC3158170.

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Jacobs CS, Etherton MR, Lyons JL. Fungal infections of the central nervous system. Curr Infect Dis Rep. 2014 Dec;16(12):449. doi: 10.1007/s11908-014-0449-2. PubMed PMID: 25348744.

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Etherton MR, Neagu MR, Oakley DH, Koch MJ, Shin JH, Frosch MP, Berkowitz AL, Dietrich J. A 20-year-old man with back pain and lower extremity weakness. JAMA Neurol. 2015 Mar;72(3):363-6. doi: 10.1001/jamaneurol.2014.3833. PubMed PMID: 25621865.

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Etherton MR, Lyons JL, Ard KL. HIV-associated Neurocognitive Disorders and Antiretroviral Therapy: Current Concepts and Controversies. Curr Infect Dis Rep. 2015 Jun;17(6):485. doi: 10.1007/s11908-015-0485-6. PubMed PMID: 25916996.

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McKee KE, Etherton MR, Lovitch SB, Gupta AS, Micalizzi DS, Tierney T, Wadleigh M, Vaitkevicus H. A Man in His 40s With Headache, Lethargy, and Altered Mental Status. JAMA Neurol. 2015 Sep;72(9):1061-5. doi: 10.1001/jamaneurol.2015.1375. PubMed PMID: 26213984; PubMed Central PMCID: PMC5761060.

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Gupta A, Etherton MR, McKee K, Baker JM, Izzy S, Feske SK. Clinical Reasoning: A 68-year-old man with a history of lung cancer presenting with right-sided weakness and aphasia. Neurology. 2015 Oct 6;85(14):e104-7. doi: 10.1212/WNL.0000000000001992. PubMed PMID: 26438622; PubMed Central PMCID: PMC4607602.

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Levin SN, de Gusmao CM, Etherton MR, Will Rondeau M, Meredith DM, Folkerth RD, Klein JP, Nadeem O, Castillo JJ. "All the soarings of my mind begin in my blood:" central nervous system complication of Waldenström macroglobulinemia. Am J Hematol. 2016 Oct;91(10):1057-60. doi: 10.1002/ajh.24476. Epub 2016 Jul 29. PubMed PMID: 27414991.

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Etherton MR, Wu O, Rost NS. Recent Advances in Leukoaraiosis: White Matter Structural Integrity and Functional Outcomes after Acute Ischemic Stroke. Curr Cardiol Rep. 2016 Dec;18(12):123. doi: 10.1007/s11886-016-0803-0. Review. PubMed PMID: 27796861.

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Etherton MR, Wu O, Cougo P, Giese AK, Cloonan L, Fitzpatrick KM, Kanakis AS, Boulouis G, Karadeli HH, Lauer A, Rosand J, Furie KL, Rost NS. Integrity of normal-appearing white matter and functional outcomes after acute ischemic stroke. Neurology. 2017 May 2;88(18):1701-1708. doi: 10.1212/WNL.0000000000003890. Epub 2017 Apr 5. PubMed PMID: 28381507; PubMed Central PMCID: PMC5409847.

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Etherton MR, Wu O, Cougo P, Giese AK, Cloonan L, Fitzpatrick KM, Kanakis AS, Boulouis G, Karadeli HH, Lauer A, Rosand J, Furie KL, Rost NS. Structural Integrity of Normal Appearing White Matter and Sex-Specific Outcomes After Acute Ischemic Stroke. Stroke. 2017 Dec;48(12):3387-3389. doi: 10.1161/STROKEAHA.117.019258. Epub 2017 Nov 10. PubMed PMID: 29127272; PubMed Central PMCID: PMC5726524.

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Rost NS, Cougo P, Lorenzano S, Li H, Cloonan L, Bouts MJ, Lauer A, Etherton MR, Karadeli HH, Musolino PL, Copen WA, Arai K, Lo EH, Feske SK, Furie KL, Wu O. Diffuse microvascular dysfunction and loss of white matter integrity predict poor outcomes in patients with acute ischemic stroke. J Cereb Blood Flow Metab. 2018 Jan;38(1):75-86. doi: 10.1177/0271678X17706449. Epub 2017 May 8. PubMed PMID: 28481164; PubMed Central PMCID: PMC5757442.

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Snider S, Stojanovic K, Donnelly D, Etherton M, Feske SK, Izzy S. Clinical Problem-Solving: Lethargy and Fever in an Immunocompromised Patient. Neurohospitalist. 2018 Jan;8(1):38-41. doi: 10.1177/1941874417717862. Epub 2017 Jul 24. PubMed PMID: 29276563; PubMed Central PMCID: PMC5734509.

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Etherton MR, Siddiqui KA, Schwamm LH. Prestroke selective serotonin reuptake inhibitor use and functional outcomes after ischaemic stroke. Stroke Vasc Neurol. 2018 Mar;3(1):9-16. doi: 10.1136/svn-2017-000119. eCollection 2018 Mar. PubMed PMID: 29600002; PubMed Central PMCID: PMC5870643.

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Etherton MR, Schwamm LH. Telestroke for the Newly Minted Vascular Neurologist. Stroke. 2018 Apr;49(4):e162-e164. doi: 10.1161/STROKEAHA.117.020548. Epub 2018 Mar 6. Review. PubMed PMID: 29511127.

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Harris WS, Tintle NL, Etherton MR, Vasan RS. Erythrocyte long-chain omega-3 fatty acid levels are inversely associated with mortality and with incident cardiovascular disease: The Framingham Heart Study. J Clin Lipidol. 2018 May - Jun;12(3):718-727.e6. doi: 10.1016/j.jacl.2018.02.010. Epub 2018 Mar 2. PubMed PMID: 29559306; PubMed Central PMCID: PMC6034629.

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Etherton MR, Barreto AD, Schwamm LH, Wu O. Neuroimaging Paradigms to Identify Patients for Reperfusion Therapy in Stroke of Unknown Onset. Front Neurol. 2018;9:327. doi: 10.3389/fneur.2018.00327. eCollection 2018. Review. PubMed PMID: 29867736; PubMed Central PMCID: PMC5962731.

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Etherton MR, Rost NS, Wu O. Infarct topography and functional outcomes. J Cereb Blood Flow Metab. 2018 Sep;38(9):1517-1532. doi: 10.1177/0271678X17700666. Epub 2017 Mar 27. Review. PubMed PMID: 28345373; PubMed Central PMCID: PMC6125960.

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Schirmer MD, Etherton Md PhD MR, Dalca PhD AV, Giese Md AK, Cloonan MSc L, Wu PhD O, Golland PhD P, Rost Md Mph Faan NS. Effective Reserve: A Latent Variable to Improve Outcome Prediction in Stroke. J Stroke Cerebrovasc Dis. 2019 Jan;28(1):63-69. doi: 10.1016/j.jstrokecerebrovasdis.2018.09.003. Epub 2018 Sep 28. PubMed PMID: 30269881; PubMed Central PMCID: PMC6289856.

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Schirmer MD, Giese AK, Fotiadis P, Etherton MR, Cloonan L, Viswanathan A, Greenberg SM, Wu O, Rost NS. Spatial Signature of White Matter Hyperintensities in Stroke Patients. Front Neurol. 2019;10:208. doi: 10.3389/fneur.2019.00208. eCollection 2019. PubMed PMID: 30941083; PubMed Central PMCID: PMC6433778.

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Wu O, Winzeck S, Giese AK, Hancock BL, Etherton MR, Bouts MJRJ, Donahue K, Schirmer MD, Irie RE, Mocking SJT, McIntosh EC, Bezerra R, Kamnitsas K, Frid P, Wasselius J, Cole JW, Xu H, Holmegaard L, Jiménez-Conde J, Lemmens R, Lorentzen E, McArdle PF, Meschia JF, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Stanne TM, Thijs V, Vagal A, Woo D, Bevan S, Kittner SJ, Mitchell BD, Rosand J, Worrall BB, Jern C, Lindgren AG, Maguire J, Rost NS. Big Data Approaches to Phenotyping Acute Ischemic Stroke Using Automated Lesion Segmentation of Multi-Center Magnetic Resonance Imaging Data. Stroke. 2019 Jul;50(7):1734-1741. doi: 10.1161/STROKEAHA.119.025373. Epub 2019 Jun 10. PubMed PMID: 31177973; PubMed Central PMCID: PMC6728139.

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Schirmer MD, Ktena SI, Nardin MJ, Donahue KL, Giese AK, Etherton MR, Wu O, Rost NS. Rich-Club Organization: An Important Determinant of Functional Outcome After Acute Ischemic Stroke. Front Neurol. 2019;10:956. doi: 10.3389/fneur.2019.00956. eCollection 2019. PubMed PMID: 31551913; PubMed Central PMCID: PMC6748157.

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Ktena SI, Schirmer MD, Etherton MR, Giese AK, Tuozzo C, Mills BB, Rueckert D, Wu O, Rost NS. Brain Connectivity Measures Improve Modeling of Functional Outcome After Acute Ischemic Stroke. Stroke. 2019 Oct;50(10):2761-2767. doi: 10.1161/STROKEAHA.119.025738. Epub 2019 Sep 12. PubMed PMID: 31510905; PubMed Central PMCID: PMC6756947.

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Etherton MR, Wu O, Giese AK, Lauer A, Boulouis G, Mills B, Cloonan L, Donahue KL, Copen W, Schaefer P, Rost NS. White Matter Integrity and Early Outcomes After Acute Ischemic Stroke. Transl Stroke Res. 2019 Dec;10(6):630-638. doi: 10.1007/s12975-019-0689-4. Epub 2019 Jan 28. PubMed PMID: 30693424.

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Etherton MR, Wu O, Cougo P, Lorenzano S, Li H, Cloonan L, Bouts MJRJ, Lauer A, Arai K, Lo EH, Feske SK, Furie KL, Rost NS. Sex-specific differences in white matter microvascular integrity after ischaemic stroke. Stroke Vasc Neurol. 2019 Dec;4(4):198-205. doi: 10.1136/svn-2019-000268. eCollection 2019 Dec. PubMed PMID: 32030203; PubMed Central PMCID: PMC6979874.

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Etherton MR, Rost NS. Redefining Normal: The Importance of White Matter Microstructural Integrity in Poststroke Outcomes. Stroke. 2020 Feb;51(2):369-370. doi: 10.1161/STROKEAHA.119.027907. Epub 2020 Jan 7. PubMed PMID: 31906827; PubMed Central PMCID: PMC7261147.

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Sharma R, Zachrison KS, Viswanathan A, Matiello M, Estrada J, Anderson CD, Etherton M, Silverman S, Rost NS, Feske SK, Schwamm LH. Trends in Telestroke Care Delivery: A 15-Year Experience of an Academic Hub and Its Network of Spokes. Circ Cardiovasc Qual Outcomes. 2020 Mar;13(3):e005903. doi: 10.1161/CIRCOUTCOMES.119.005903. Epub 2020 Mar 4. PubMed PMID: 32126805; PubMed Central PMCID: PMC7374496.

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Rost NS, Etherton M. Cerebral Small Vessel Disease. Continuum (Minneap Minn). 2020 Apr;26(2):332-352. doi: 10.1212/CON.0000000000000841. Review. PubMed PMID: 32224755.

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Schirmer MD, Donahue KL, Nardin MJ, Dalca AV, Giese AK, Etherton MR, Mocking SJT, McIntosh EC, Cole JW, Holmegaard L, Jood K, Jimenez-Conde J, Kittner SJ, Lemmens R, Meschia JF, Rosand J, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Stanne TM, Vagal A, Wasselius J, Woo D, Bevan S, Heitsch L, Phuah CL, Strbian D, Tatlisumak T, Levi CR, Attia J, McArdle PF, Worrall BB, Wu O, Jern C, Lindgren A, Maguire J, Thijs V, Rost NS. Brain Volume: An Important Determinant of Functional Outcome After Acute Ischemic Stroke. Mayo Clin Proc. 2020 May;95(5):955-965. doi: 10.1016/j.mayocp.2020.01.027. PubMed PMID: 32370856; NIHMSID:NIHMS1679868.

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Turner AC, Schwamm LH, Etherton MR. Acute ischemic stroke: improving access to intravenous tissue plasminogen activator. Expert Rev Cardiovasc Ther. 2020 May;18(5):277-287. doi: 10.1080/14779072.2020.1759422. Epub 2020 May 5. Review. PubMed PMID: 32323590.

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Etherton MR, Gadhia RR, Schwamm LH. Thrombolysis beyond 4.5 h in Acute Ischemic Stroke. Curr Neurol Neurosci Rep. 2020 Jun 30;20(8):35. doi: 10.1007/s11910-020-01055-1. Review. PubMed PMID: 32607627.

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Dubost F, Bruijne M, Nardin M, Dalca AV, Donahue KL, Giese AK, Etherton MR, Wu O, Groot M, Niessen W, Vernooij M, Rost NS, Schirmer MD. Multi-atlas image registration of clinical data with automated quality assessment using ventricle segmentation. Med Image Anal. 2020 Jul;63:101698. doi: 10.1016/j.media.2020.101698. Epub 2020 Apr 18. Review. PubMed PMID: 32339896; PubMed Central PMCID: PMC7275913.

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Harris WS, Tintle NL, Etherton MR, Vasan RS. "Corrigendum to Erythrocyte long-chain omega-3 fatty acid levels are inversely associated with mortality and with incident cardiovascular disease: The Framingham Heart Study" Journal of Clinical Lipidology Volume 12, Issue 3, May-June 2018, Pages 718-727.e6. J Clin Lipidol. 2020 Sep - Oct;14(5):740. doi: 10.1016/j.jacl.2020.08.010. PubMed PMID: 33138960.

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Etherton MR, Fotiadis P, Giese AK, Iglesias JE, Wu O, Rost NS. White Matter Hyperintensity Burden Is Associated With Hippocampal Subfield Volume in Stroke. Front Neurol. 2020;11:588883. doi: 10.3389/fneur.2020.588883. eCollection 2020. PubMed PMID: 33193055; PubMed Central PMCID: PMC7649326.

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Simpkins AN, Busl KM, Amorim E, Barnett-Tapia C, Cervenka MC, Dhakar MB, Etherton MR, Fung C, Griggs R, Holloway RG, Kelly AG, Khan IR, Lizarraga KJ, Madagan HG, Onweni CL, Mestre H, Rabinstein AA, Rubinos C, Dionisio-Santos DA, Youn TS, Merck LH, Maciel CB. Proceedings from the Neurotherapeutics Symposium on Neurological Emergencies: Shaping the Future of Neurocritical Care. Neurocrit Care. 2020 Dec;33(3):636-645. doi: 10.1007/s12028-020-01085-0. Epub 2020 Sep 21. PubMed PMID: 32959201; PubMed Central PMCID: PMC7736003.

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Regenhardt RW, Etherton MR, Das AS, Schirmer MD, Hirsch JA, Stapleton CJ, Patel AB, Leslie-Mazwi TM, Rost NS. Infarct Growth despite Endovascular Thrombectomy Recanalization in Large Vessel Occlusive Stroke. J Neuroimaging. 2021 Jan;31(1):155-164. doi: 10.1111/jon.12796. Epub 2020 Oct 29. PubMed PMID: 33119954; PubMed Central PMCID: PMC8365346.

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Etherton MR, Wu O, Giese AK, Rost NS. Normal-appearing white matter microstructural injury is associated with white matter hyperintensity burden in acute ischemic stroke. Int J Stroke. 2021 Feb;16(2):184-191. doi: 10.1177/1747493019895707. Epub 2019 Dec 17. PubMed PMID: 31847795.

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Regenhardt RW, Etherton MR, Das AS, Schirmer MD, Hirsch JA, Stapleton CJ, Patel AB, Leslie-Mazwi TM, Rost NS. White Matter Acute Infarct Volume After Thrombectomy for Anterior Circulation Large Vessel Occlusion Stroke is Associated with Long Term Outcomes. J Stroke Cerebrovasc Dis. 2021 Mar;30(3):105567. doi: 10.1016/j.jstrokecerebrovasdis.2020.105567. Epub 2020 Dec 29. PubMed PMID: 33385939; PubMed Central PMCID: PMC7880897.

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Etherton MR, Zachrison KS, Yan Z, Sveikata L, Bretzner M, Estrada J, Viswanathan A, Singhal AB, Schwamm LH. Regional Changes in Patterns of Stroke Presentation During the COVID-19 Pandemic. Stroke. 2021 Apr;52(4):1398-1406. doi: 10.1161/STROKEAHA.120.031300. Epub 2021 Feb 16. PubMed PMID: 33588592; PubMed Central PMCID: PMC8992369.

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Bonkhoff AK, Schirmer MD, Bretzner M, Etherton M, Donahue K, Tuozzo C, Nardin M, Giese AK, Wu O, D Calhoun V, Grefkes C, Rost NS. Abnormal dynamic functional connectivity is linked to recovery after acute ischemic stroke. Hum Brain Mapp. 2021 May;42(7):2278-2291. doi: 10.1002/hbm.25366. Epub 2021 Mar 2. PubMed PMID: 33650754; PubMed Central PMCID: PMC8046120.

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Raposo N, Zanon Zotin MC, Schoemaker D, Xiong L, Fotiadis P, Charidimou A, Pasi M, Boulouis G, Schwab K, Schirmer MD, Etherton MR, Gurol ME, Greenberg SM, Duering M, Viswanathan A. Peak Width of Skeletonized Mean Diffusivity as Neuroimaging Biomarker in Cerebral Amyloid Angiopathy. AJNR Am J Neuroradiol. 2021 May;42(5):875-881. doi: 10.3174/ajnr.A7042. Epub 2021 Mar 4. PubMed PMID: 33664113; PubMed Central PMCID: PMC8115367.

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Bonkhoff AK, Schirmer MD, Bretzner M, Hong S, Regenhardt RW, Brudfors M, Donahue KL, Nardin MJ, Dalca AV, Giese AK, Etherton MR, Hancock BL, Mocking SJT, McIntosh EC, Attia J, Benavente OR, Bevan S, Cole JW, Donatti A, Griessenauer CJ, Heitsch L, Holmegaard L, Jood K, Jimenez-Conde J, Kittner SJ, Lemmens R, Levi CR, McDonough CW, Meschia JF, Phuah CL, Rolfs A, Ropele S, Rosand J, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Söderholm M, Sousa A, Stanne TM, Strbian D, Tatlisumak T, Thijs V, Vagal A, Wasselius J, Woo D, Zand R, McArdle PF, Worrall BB, Jern C, Lindgren AG, Maguire J, Bzdok D, Wu O, Rost NS. Outcome after acute ischemic stroke is linked to sex-specific lesion patterns. Nat Commun. 2021 Jun 2;12(1):3289. doi: 10.1038/s41467-021-23492-3. PubMed PMID: 34078897; PubMed Central PMCID: PMC8172535.