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Hyle EP, Wattananimitgul N, Mukerji SS, Foote JHA, Reddy KP, Thielking A, Yu L, Viswanathan A, Rubin LH, Shebl FM, Althoff KN, Freedberg KA. Age-associated dementia among older people aging with HIV in the US: a modeling study. AIDS. 2024 Feb 8;. doi: 10.1097/QAD.0000000000003862. [Epub ahead of print] PubMed PMID: 38329107; NIHMSID:NIHMS1964340.
Novotna K, Thomas AG, Stepanek O, Murphy B, Hin N, Skacel J, Mueller L, Tenora L, Pal A, Alt J, Wu Y, Paule J, Rais R, Slusher BS, Tsukamoto T. Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold. Eur J Med Chem. 2023 Nov 5;259:115674. doi: 10.1016/j.ejmech.2023.115674. Epub 2023 Jul 26. PubMed PMID: 37536209; PubMed Central PMCID: PMC10529203.
Rubin LH, O'Halloran JA, Williams DW, Li Y, Fitzgerald KC, Dastgheyb R, Damron AL, Maki PM, Spence AB, Sharma A, Gustafson DR, Milam J, Weber KM, Adimora AA, Ofotokun I, Fischl MA, Konkle-Parker D, Xu Y. Integrase Inhibitors are Associated with Neuropsychiatric Symptoms in Women with HIV. J Neuroimmune Pharmacol. 2023 Jun;18(1-2):1-8. doi: 10.1007/s11481-021-10042-3. Epub 2022 Feb 17. PubMed PMID: 35178611; PubMed Central PMCID: PMC9381649.
Veenhuis RT, Abreu CM, Costa PAG, Ferreira EA, Ratliff J, Pohlenz L, Shirk EN, Rubin LH, Blankson JN, Gama L, Clements JE. Monocyte-derived macrophages contain persistent latent HIV reservoirs. Nat Microbiol. 2023 May;8(5):833-844. doi: 10.1038/s41564-023-01349-3. Epub 2023 Mar 27. PubMed PMID: 36973419; PubMed Central PMCID: PMC10159852.
Rubin LH, Maki PM, Dastgheyb RM, Steigman PJ, Burke-Miller J, Xu Y, Jin W, Sosanya O, Gustafson D, Merenstein D, Milam J, Weber KM, Springer G, Cook JA. Trauma Across the Life Span and Multisystem Morbidity in Women With HIV. Psychosom Med. 2023 May 1;85(4):341-350. doi: 10.1097/PSY.0000000000001192. Epub 2023 Mar 15. PubMed PMID: 36961349; PubMed Central PMCID: PMC10450638.
Njie-Carr VPS, Zhu S, Stafford KA, Tong W, Plankey M, Sharma A, Milam J, Cohen M, Diaz MM, Rubtsova AA, Fischl MA, Konkle-Parker D, Gustafson D, Rubin LH. Intersectionality of Socioecological Factors Associated With Cognitive Function Among Older Women With HIV in the United States: A Structural Equation Model Analysis Using Data From the Women's Interagency HIV Study. J Assoc Nurses AIDS Care. 2023 Jan-Feb 01;34(1):83-95. doi: 10.1097/JNC.0000000000000376. Epub 2022 Dec 12. PubMed PMID: 36656093; PubMed Central PMCID: PMC10079306.
Castell N, Guerrero-Martin SM, Rubin LH, Shirk EN, Brockhurst JK, Lyons CE, Najarro KM, Queen SE, Carlson BW, Adams RJ, Morrell CN, Gama L, Graham DR, Zink C, Mankowski JL, Clements JE, Metcalf Pate KA. Effect of Single Housing on Innate Immune Activation in Immunodeficiency Virus-Infected Pigtail Macaques ( Macaca nemestrina ) as a Model of Psychosocial Stress in Acute HIV Infection. Psychosom Med. 2022 Oct 1;84(8):966-975. doi: 10.1097/PSY.0000000000001132. Epub 2022 Sep 7. PubMed PMID: 36162063; PubMed Central PMCID: PMC9553260.
Shortell DD, Rubin LH, Murphy AJ, Cohen RA, Porges EC. The Association Between Peripheral Oxytocin Levels and Depressive Symptoms in People With HIV. Psychosom Med. 2022 Oct 1;84(8):885-892. doi: 10.1097/PSY.0000000000001122. Epub 2022 Aug 16. PubMed PMID: 35980773; PubMed Central PMCID: PMC9553265.
Rubin LH, Bhattacharya D, Fuchs J, Matthews A, Abdellah S, Veenhuis RT, Langenecker SA, Weber KM, Nazarloo HP, Keating SM, Carter CS, Maki PM. Early Life Trauma and Social Processing in HIV: The Role of Neuroendocrine Factors and Inflammation. Psychosom Med. 2022 Oct 1;84(8):874-884. doi: 10.1097/PSY.0000000000001124. Epub 2022 Aug 20. PubMed PMID: 36044606; PubMed Central PMCID: PMC9553269.
Zhu X, Hollinger KR, Huang Y, Borjabad A, Kim BH, Arab T, Thomas AG, Moniruzzaman M, Lovell L, Turchinovich A, Witwer KW, Volsky DJ, Haughey NJ, Slusher BS. Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV. Neurobiol Dis. 2022 Jul;169:105734. doi: 10.1016/j.nbd.2022.105734. Epub 2022 Apr 21. PubMed PMID: 35462006; PubMed Central PMCID: PMC9202342.
Tallon C, Picciolini S, Yoo SW, Thomas AG, Pal A, Alt J, Carlomagno C, Gualerzi A, Rais R, Haughey NJ, Bedoni M, Slusher BS. Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury. Biochem Pharmacol. 2021 Dec;194:114796. doi: 10.1016/j.bcp.2021.114796. Epub 2021 Oct 20. PubMed PMID: 34678224; PubMed Central PMCID: PMC8919377.
Gao RD, Hin N, Prchalová E, Pal A, Lam J, Rais R, Slusher BS, Tsukamoto T. Model studies towards prodrugs of the glutamine antagonist 6-diazo-5-oxo-l-norleucine (DON) containing a diazo precursor. Bioorg Med Chem Lett. 2021 Oct 15;50:128321. doi: 10.1016/j.bmcl.2021.128321. Epub 2021 Aug 13. PubMed PMID: 34400301; PubMed Central PMCID: PMC8607733.
Kamkwalala AR, Maki PM, Langenecker SA, Phan KL, Weber KM, Rubin LH. Sex-specific effects of low-dose hydrocortisone on threat detection in HIV. J Neurovirol. 2021 Oct;27(5):716-726. doi: 10.1007/s13365-021-01007-6. Epub 2021 Sep 24. PubMed PMID: 34559394; PubMed Central PMCID: PMC10478032.
Massanett Aparicio J, Xu Y, Li Y, Colantuoni C, Dastgheyb R, Williams DW, Asahchop EL, McMillian JM, Power C, Fujiwara E, Gill MJ, Rubin LH. Plasma microRNAs are associated with domain-specific cognitive function in people with HIV. AIDS. 2021 Sep 1;35(11):1795-1804. doi: 10.1097/QAD.0000000000002966. PubMed PMID: 34074816; PubMed Central PMCID: PMC8524348.
Nakasujja N, Vecchio AC, Saylor D, Lofgren S, Nakigozi G, Boulware DR, Kisakye A, Batte J, Mayanja R, Anok A, Reynolds SJ, Quinn TC, Pardo CA, Kumar A, Gray RH, Wawer MJ, Sacktor N, Rubin LH. Improvement in depressive symptoms after antiretroviral therapy initiation in people with HIV in Rakai, Uganda. J Neurovirol. 2021 Aug;27(4):519-530. doi: 10.1007/s13365-020-00920-6. Epub 2021 Jul 31. PubMed PMID: 34333739; PubMed Central PMCID: PMC8524346.
Nowakowski S, Meers JM. Cognitive-behavior therapy for sleep disorders at midlife. Menopause. 2021 May 24;28(7):833-835. doi: 10.1097/GME.0000000000001771. PubMed PMID: 34033600.
O'Halloran JA, Wang K, Spence AB, Williams DW, Dastgheyb R, Fitzgerald KC, Kamkwalala AR, Maki PM, Sharma A, Gustafson DR, Milam J, Weber KM, Adimora AA, Ofotokun I, Fischl MA, Konkle-Parker D, Lahiri CD, Sheth AN, Xu Y, Rubin LH. Integrase Strand Transfer Inhibitor Start or Switch Impacts Learning in Women With HIV. J Acquir Immune Defic Syndr. 2021 Apr 15;86(5):593-599. doi: 10.1097/QAI.0000000000002608. PubMed PMID: 33394812; PubMed Central PMCID: PMC8319920.
Tran A, Thakur KT, Nakasujja N, Nakigozi G, Kisakye A, Batte J, Mayanja R, Anok A, Gray RH, Wawer MJ, Rubin LH, Sacktor N, Saylor D. Evaluation of a screening tool for the identification of neurological disorders in rural Uganda. J Neurol Sci. 2021 Feb 15;421:117273. doi: 10.1016/j.jns.2020.117273. Epub 2020 Dec 24. PubMed PMID: 33423010; PubMed Central PMCID: PMC7914201.
Skácel J, Slusher BS, Tsukamoto T. Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network. J Med Chem. 2021 Jan 14;64(1):279-297. doi: 10.1021/acs.jmedchem.0c01664. Epub 2021 Jan 4. Review. PubMed PMID: 33395289; PubMed Central PMCID: PMC8023021.
Maki PM, Springer G, Anastos K, Gustafson DR, Weber K, Vance D, Dykxhoorn D, Milam J, Adimora AA, Kassaye SG, Waldrop D, Rubin LH. Cognitive changes during the menopausal transition: a longitudinal study in women with and without HIV. Menopause. 2021 Jan 11;28(4):360-368. doi: 10.1097/GME.0000000000001725. PubMed PMID: 33438895; PubMed Central PMCID: PMC8576848.
Kamkwalala AR, Wang K, O'Halloran J, Williams DW, Dastgheyb R, Fitzgerald KC, Spence AB, Maki PM, Gustafson DR, Milam J, Sharma A, Weber KM, Adimora AA, Ofotokun I, Sheth AN, Lahiri CD, Fischl MA, Konkle-Parker D, Xu Y, Rubin LH. Starting or Switching to an Integrase Inhibitor-Based Regimen Affects PTSD Symptoms in Women with HIV. AIDS Behav. 2021 Jan;25(1):225-236. doi: 10.1007/s10461-020-02967-2. PubMed PMID: 32638219; PubMed Central PMCID: PMC7948485.
Duvall B, Zimmermann SC, Gao RD, Thomas AG, Kalčic F, Veeravalli V, Elgogary A, Rais R, Rojas C, Le A, Slusher BS, Tsukamoto T. Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker. Bioorg Med Chem. 2020 Oct 15;28(20):115698. doi: 10.1016/j.bmc.2020.115698. Epub 2020 Aug 6. PubMed PMID: 33069080; PubMed Central PMCID: PMC9115729.
Braxton AM, Chalmin AL, Najarro KM, Brockhurst JK, Johnson KT, Lyons CE, Daly B, Cryer CG, Vijay S, Cyphers G, Guerrero-Martin SM, Aston SA, McGee K, Su YP, Arav-Boger R, Metcalf Pate KA. Platelet-endothelial associations may promote cytomegalovirus replication in the salivary gland in mice. Platelets. 2020 Oct 2;31(7):860-868. doi: 10.1080/09537104.2019.1689383. Epub 2019 Nov 14. PubMed PMID: 31726921; PubMed Central PMCID: PMC7220825.
Holroyd KB, Vishnevetsky A, Srinivasan M, Saylor D. Neurologic Complications of Acute HIV Infection. Curr Treat Options Infect Dis. 2020 Sep;12(3):227-242. doi: 10.1007/s40506-020-00228-3. Epub 2020 Jun 8. PubMed PMID: 33551684; PubMed Central PMCID: PMC7864540.
Vornov JJ, Peters D, Nedelcovych M, Hollinger K, Rais R, Slusher BS. Looking for Drugs in All the Wrong Places: Use of GCPII Inhibitors Outside the Brain. Neurochem Res. 2020 Jun;45(6):1256-1267. doi: 10.1007/s11064-019-02909-y. Epub 2019 Nov 20. Review. PubMed PMID: 31749072; PubMed Central PMCID: PMC7237296.
Deme P, Rojas C, Slusher BS, Rais R, Afghah Z, Geiger JD, Haughey NJ. Bioenergetic adaptations to HIV infection. Could modulation of energy substrate utilization improve brain health in people living with HIV-1?. Exp Neurol. 2020 May;327:113181. doi: 10.1016/j.expneurol.2020.113181. Epub 2020 Jan 11. Review. PubMed PMID: 31930991; PubMed Central PMCID: PMC7233457.
Kamkwalala AR, Wang X, Maki PM, Williams DW, Valcour VG, Damron A, Tien PC, Weber KM, Cohen MH, Sundermann EE, Meyer VJ, Little DM, Xu Y, Rubin LH. Brief Report: Higher Peripheral Monocyte Activation Markers Are Associated With Smaller Frontal and Temporal Cortical Volumes in Women With HIV. J Acquir Immune Defic Syndr. 2020 May 1;84(1):54-59. doi: 10.1097/QAI.0000000000002283. PubMed PMID: 31914004; PubMed Central PMCID: PMC7388688.
Rubin LH, Langenecker SA, Phan KL, Keating SM, Neigh GN, Weber KM, Maki PM. Remitted depression and cognition in HIV: The role of cortisol and inflammation. Psychoneuroendocrinology. 2020 Apr;114:104609. doi: 10.1016/j.psyneuen.2020.104609. Epub 2020 Feb 7. PubMed PMID: 32062371; PubMed Central PMCID: PMC7254879.
Awori V, Nakigozi G, Kisakye A, Batte J, Anok A, Mayanja R, Nakasujja N, Robertson KR, Gray RH, Wawer MJ, Sacktor N, Saylor D. The Veterans Aging Cohort Study Index is not associated with HIV-associated neurocognitive disorders in Uganda. J Neurovirol. 2020 Apr;26(2):252-256. doi: 10.1007/s13365-019-00806-2. Epub 2019 Nov 12. PubMed PMID: 31721082; PubMed Central PMCID: PMC8012007.
Saleem M, Herrmann N, Dinoff A, Marzolini S, Mielke MM, Andreazza A, Oh PI, Vattem Venkata SL, Haughey NJ, Lanctôt KL. Association Between Sphingolipids and Cardiopulmonary Fitness in Coronary Artery Disease Patients Undertaking Cardiac Rehabilitation. J Gerontol A Biol Sci Med Sci. 2020 Mar 9;75(4):671-679. doi: 10.1093/gerona/gly273. PubMed PMID: 30535238; PubMed Central PMCID: PMC7931966.
Molinaro M, Sacktor N, Nakigozi G, Anok A, Batte J, Kisakye A, Myanja R, Nakasujja N, Robertson KR, Gray RH, Wawer MJ, Saylor D. Utility of the International HIV Dementia Scale for HIV-Associated Neurocognitive Disorder. J Acquir Immune Defic Syndr. 2020 Mar 1;83(3):278-283. doi: 10.1097/QAI.0000000000002257. PubMed PMID: 32032278; PubMed Central PMCID: PMC7197883.
Saylor D, Kumar A, Nakigozi G, Anok A, Batte J, Kisakye A, Mayanja R, Nakasujja N, Robertson KR, Gray RH, Wawer MJ, Pardo CA, Sacktor N. Interleukin-6 is associated with mortality and neuropsychiatric outcomes in antiretroviral-naïve adults in Rakai, Uganda. J Neurovirol. 2019 Dec;25(6):735-740. doi: 10.1007/s13365-019-00759-6. Epub 2019 Jun 4. PubMed PMID: 31165368; PubMed Central PMCID: PMC6891138.
Rubin LH, Saylor D, Nakigozi G, Nakasujja N, Robertson K, Kisakye A, Batte J, Mayanja R, Anok A, Lofgren SM, Boulware DR, Dastgheyb R, Reynolds SJ, Quinn TC, Gray RH, Wawer MJ, Sacktor N. Heterogeneity in neurocognitive change trajectories among people with HIV starting antiretroviral therapy in Rakai, Uganda. J Neurovirol. 2019 Dec;25(6):800-813. doi: 10.1007/s13365-019-00768-5. Epub 2019 Jun 19. PubMed PMID: 31218522; PubMed Central PMCID: PMC7296988.
Cotto B, Natarajaseenivasan K, Langford D. Astrocyte activation and altered metabolism in normal aging, age-related CNS diseases, and HAND. J Neurovirol. 2019 Oct;25(5):722-733. doi: 10.1007/s13365-019-00721-6. Epub 2019 Jan 22. Review. PubMed PMID: 30671779; PubMed Central PMCID: PMC6646105.
Rojas C, Sala M, Thomas AG, Datta Chaudhuri A, Yoo SW, Li Z, Dash RP, Rais R, Haughey NJ, Nencka R, Slusher B. A novel and potent brain penetrant inhibitor of extracellular vesicle release. Br J Pharmacol. 2019 Oct;176(19):3857-3870. doi: 10.1111/bph.14789. Epub 2019 Sep 4. PubMed PMID: 31273753; PubMed Central PMCID: PMC6780992.
Nedelcovych MT, Kim BH, Zhu X, Lovell LE, Manning AA, Kelschenbach J, Hadas E, Chao W, Prchalová E, Dash RP, Wu Y, Alt J, Thomas AG, Rais R, Kamiya A, Volsky DJ, Slusher BS. Glutamine Antagonist JHU083 Normalizes Aberrant Glutamate Production and Cognitive Deficits in the EcoHIV Murine Model of HIV-Associated Neurocognitive Disorders. J Neuroimmune Pharmacol. 2019 Sep;14(3):391-400. doi: 10.1007/s11481-019-09859-w. Epub 2019 Jun 17. PubMed PMID: 31209775; PubMed Central PMCID: PMC8207835.
Rubin LH, Springer G, Martin EM, Seaberg EC, Sacktor NC, Levine A, Valcour VG, Young MA, Becker JT, Maki PM. Elevated Depressive Symptoms Are a Stronger Predictor of Executive Dysfunction in HIV-Infected Women Than in Men. J Acquir Immune Defic Syndr. 2019 Jul 1;81(3):274-283. doi: 10.1097/QAI.0000000000002029. PubMed PMID: 30893126; PubMed Central PMCID: PMC7254882.
Kisakye A, Saylor D, Sacktor N, Nakigozi G, Nakasujja N, Robertson K, Anok A, Wawer M, Gray R. Caregiver versus self-reported activities of daily living among HIV-positive persons in Rakai, Uganda. AIDS Care. 2019 Jul;31(7):836-839. doi: 10.1080/09540121.2018.1557591. Epub 2018 Dec 15. PubMed PMID: 30554522; PubMed Central PMCID: PMC6510610.
Saylor D, Nakigozi G, Pardo CA, Kisakye A, Kumar A, Nakasujja N, Robertson KR, Gray RH, Wawer MJ, Sacktor N. Vitamin D is not associated with HIV-associated neurocognitive disorder in Rakai, Uganda. J Neurovirol. 2019 Jun;25(3):410-414. doi: 10.1007/s13365-018-00719-6. Epub 2019 Jan 22. PubMed PMID: 30671778; PubMed Central PMCID: PMC6635069.
Sacktor N, Saylor D, Nakigozi G, Nakasujja N, Robertson K, Grabowski MK, Kisakye A, Batte J, Mayanja R, Anok A, Gray RH, Wawer MJ. Effect of HIV Subtype and Antiretroviral Therapy on HIV-Associated Neurocognitive Disorder Stage in Rakai, Uganda. J Acquir Immune Defic Syndr. 2019 Jun 1;81(2):216-223. doi: 10.1097/QAI.0000000000001992. PubMed PMID: 30865184; PubMed Central PMCID: PMC6522269.
Stepanek O, Hin N, Thomas AG, Dash RP, Alt J, Rais R, Rojas C, Slusher BS, Tsukamoto T. Neutral sphingomyelinase 2 inhibitors based on the 4-(1H-imidazol-2-yl)-2,6-dialkoxyphenol scaffold. Eur J Med Chem. 2019 May 15;170:276-289. doi: 10.1016/j.ejmech.2019.03.015. Epub 2019 Mar 9. PubMed PMID: 30921693; PubMed Central PMCID: PMC9850959.
Robertson KR, Jiang H, Kumwenda J, Supparatpinyo K, Marra CM, Berzins B, Hakim J, Sacktor N, Campbell TB, Schouten J, Mollan K, Tripathy S, Kumarasamy N, La Rosa A, Santos B, Silva MT, Kanyama C, Firhnhaber C, Murphy R, Hall C, Marcus C, Naini L, Masih R, Hosseinipour MC, Mngqibisa R, Badal-Faesen S, Yosief S, Vecchio A, Nair A. Human Immunodeficiency Virus-associated Neurocognitive Impairment in Diverse Resource-limited Settings. Clin Infect Dis. 2019 May 2;68(10):1733-1738. doi: 10.1093/cid/ciy767. PubMed PMID: 30219843; PubMed Central PMCID: PMC6495019.
Kim BH, Kelschenbach J, Borjabad A, Hadas E, He H, Potash MJ, Nedelcovych MT, Rais R, Haughey NJ, McArthur JC, Slusher BS, Volsky DJ. Intranasal insulin therapy reverses hippocampal dendritic injury and cognitive impairment in a model of HIV-associated neurocognitive disorders in EcoHIV-infected mice. AIDS. 2019 May 1;33(6):973-984. doi: 10.1097/QAD.0000000000002150. PubMed PMID: 30946151; PubMed Central PMCID: PMC6457131.
Zhu X, Nedelcovych MT, Thomas AG, Hasegawa Y, Moreno-Megui A, Coomer W, Vohra V, Saito A, Perez G, Wu Y, Alt J, Prchalova E, Tenora L, Majer P, Rais R, Rojas C, Slusher BS, Kamiya A. Correction: JHU-083 selectively blocks glutaminase activity in brain CD11b(+) cells and prevents depression-associated behaviors induced by chronic social defeat stress. Neuropsychopharmacology. 2019 May;44(6):1178. doi: 10.1038/s41386-019-0354-3. Epub 2019 Mar 13. PubMed PMID: 30862949; PubMed Central PMCID: PMC6461747.
Sohail S, Nakigozi G, Anok A, Batte J, Kisakye A, Mayanja R, Nakasujja N, Robertson KR, Gray RH, Wawer MJ, Sacktor N, Saylor D. Headache prevalence and its functional impact among HIV-infected adults in rural Rakai District, Uganda. J Neurovirol. 2019 Apr;25(2):248-253. doi: 10.1007/s13365-018-0710-9. Epub 2019 Jan 3. PubMed PMID: 30607892; PubMed Central PMCID: PMC6506364.
Khuder SS, Chen S, Letendre S, Marcotte T, Grant I, Franklin D, Rubin LH, Margolick JB, Jacobson LP, Sacktor N, D'Souza G, Stosor V, Lake JE, Rapocciolo G, McArthur JC, Dickens AM, Haughey NJ. Impaired insulin sensitivity is associated with worsening cognition in HIV-infected patients. Neurology. 2019 Mar 19;92(12):e1344-e1353. doi: 10.1212/WNL.0000000000007125. Epub 2019 Feb 20. PubMed PMID: 30787163; PubMed Central PMCID: PMC6511093.
Zhu X, Nedelcovych MT, Thomas AG, Hasegawa Y, Moreno-Megui A, Coomer W, Vohra V, Saito A, Perez G, Wu Y, Alt J, Prchalova E, Tenora L, Majer P, Rais R, Rojas C, Slusher BS, Kamiya A. JHU-083 selectively blocks glutaminase activity in brain CD11b(+) cells and prevents depression-associated behaviors induced by chronic social defeat stress. Neuropsychopharmacology. 2019 Mar;44(4):683-694. doi: 10.1038/s41386-018-0177-7. Epub 2018 Aug 13. PubMed PMID: 30127344; PubMed Central PMCID: PMC6372721.
Rubin LH, Maki PM. HIV, Depression, and Cognitive Impairment in the Era of Effective Antiretroviral Therapy. Curr HIV/AIDS Rep. 2019 Feb;16(1):82-95. doi: 10.1007/s11904-019-00421-0. Review. PubMed PMID: 30661180; PubMed Central PMCID: PMC6420829.
Barinka C, Novakova Z, Hin N, Bím D, Ferraris DV, Duvall B, Kabarriti G, Tsukamoto R, Budesinsky M, Motlova L, Rojas C, Slusher BS, Rokob TA, Rulíšek L, Tsukamoto T. Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors. Bioorg Med Chem. 2019 Jan 15;27(2):255-264. doi: 10.1016/j.bmc.2018.11.022. Epub 2018 Nov 14. PubMed PMID: 30552009; PubMed Central PMCID: PMC6374116.
Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer M, Slusher BS. DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation. Sci Rep. 2018 Dec 7;8(1):17715. doi: 10.1038/s41598-018-36144-2. PubMed PMID: 30531925; PubMed Central PMCID: PMC6286365.
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