My Bibliography

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Rosenhouse-Dantsker A, editor. Cholesterol and PI(4,5)P2 in Vital Biological Functions: From Coexistence to Crosstalk. Switzerland: Springer Nature; 2023.

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Bukiya AN, Rosenhouse-Dantsker A. From Crosstalk to Synergism: The Combined Effect of Cholesterol and PI(4,5)P(2) on Inwardly Rectifying Potassium Channels. Adv Exp Med Biol. 2023;1422:169-191. doi: 10.1007/978-3-031-21547-6_6. Review. PubMed PMID: 36988881.

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Cologna SM, Pathmasiri KC, Pergande MR, Rosenhouse-Dantsker A. Alterations in Cholesterol and Phosphoinositides Levels in the Intracellular Cholesterol Trafficking Disorder NPC. Adv Exp Med Biol. 2023;1422:143-165. doi: 10.1007/978-3-031-21547-6_5. PubMed PMID: 36988880.

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Rosenhouse-Dantsker A, Gazgalis D, Logothetis DE. PI(4,5)P(2) and Cholesterol: Synthesis, Regulation, and Functions. Adv Exp Med Biol. 2023;1422:3-59. doi: 10.1007/978-3-031-21547-6_1. PubMed PMID: 36988876.

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Rosenhouse-Dantsker A, Slayden A, Bukiya AN. Approaches for modifying cellular cholesterol levels and their application to mechanistic studies: Examples from the ion channel field. In: Bukiya AN, Dopico AM, editors. Cholesterol: From Chemistry and Biophysics to the Clinic. USA: Academic Press; 2022. Chapter 13; p.289-340.

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Wierzchowski A, Wink DJ, Zhang H, Kambanis K, Rojas Robles JO, Rosenhouse-Dantsker A. CoLab: A Workshop-Based Undergraduate Research Experience for Entering College Students. J Chem. Ed. 2022; 99:4085.

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Corradi V, Bukiya AN, Miranda WE, Cui M, Plant LD, Logothetis DE, Tieleman DP, Noskov SY, Rosenhouse-Dantsker A. A molecular switch controls the impact of cholesterol on a Kir channel. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2109431119. doi: 10.1073/pnas.2109431119. Epub 2022 Mar 25. PubMed PMID: 35333652; PubMed Central PMCID: PMC9060494.

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Pathmasiri KC, Pergande MR, Tobias F, Rebiai R, Rosenhouse-Dantsker A, Bongarzone ER, Cologna SM. Mass spectrometry imaging and LC/MS reveal decreased cerebellar phosphoinositides in Niemann-Pick type C1-null mice. J Lipid Res. 2020 Jul;61(7):1004-1013. doi: 10.1194/jlr.RA119000606. Epub 2020 May 5. PubMed PMID: 32371566; PubMed Central PMCID: PMC7328050.

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Slayden A, North K, Bisen S, Dopico AM, Bukiya AN, Rosenhouse-Dantsker A. Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol. J Vis Exp. 2020 Mar 25;(157). doi: 10.3791/60734. PubMed PMID: 32281977.

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Cologna SM, Rosenhouse-Dantsker A. Insights into the Molecular Mechanisms of Cholesterol Binding to the NPC1 and NPC2 Proteins. Adv Exp Med Biol. 2019;1135:139-160. doi: 10.1007/978-3-030-14265-0_8. Review. PubMed PMID: 31098815.

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Rosenhouse-Dantsker A. Cholesterol Binding Sites in Inwardly Rectifying Potassium Channels. Adv Exp Med Biol. 2019;1135:119-138. doi: 10.1007/978-3-030-14265-0_7. Review. PubMed PMID: 31098814.

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Wang C, Ralko A, Ren Z, Rosenhouse-Dantsker A, Yang X. Modes of Cholesterol Binding in Membrane Proteins: A Joint Analysis of 73 Crystal Structures. Adv Exp Med Biol. 2019;1135:67-86. doi: 10.1007/978-3-030-14265-0_4. Review. PubMed PMID: 31098811.

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Ounjian J, Bukiya AN, Rosenhouse-Dantsker A. Molecular Determinants of Cholesterol Binding to Soluble and Transmembrane Protein Domains. Adv Exp Med Biol. 2019;1135:47-66. doi: 10.1007/978-3-030-14265-0_3. Review. PubMed PMID: 31098810.

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Rosenhouse-Dantsker A, Bukiya AN, editors. Direct Mechanisms in Cholesterol Modulation of Protein Function. Switzerland: Springer Nature; 2019.

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Rosenhouse-Dantsker A, Bukiya AN, editors. Cholesterol Modulation of Protein function: Sterol Specificity and Indirect Mechanisms. Switzerland: Springer Nature; 2019.

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Bukiya AN, Blank PS, Rosenhouse-Dantsker A. Cholesterol intake and statin use regulate neuronal G protein-gated inwardly rectifying potassium channels. J Lipid Res. 2019 Jan;60(1):19-29. doi: 10.1194/jlr.M081240. Epub 2018 Nov 12. PubMed PMID: 30420402; PubMed Central PMCID: PMC6314255.

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Rosenhouse-Dantsker A. Cholesterol-Binding Sites in GIRK Channels: The Devil is in the Details. Lipid Insights. 2018;11:1178635317754071. doi: 10.1177/1178635317754071. eCollection 2018. PubMed PMID: 29467578; PubMed Central PMCID: PMC5815411.

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Rosenhouse-Dantsker A. Insights Into the Molecular Requirements for Cholesterol Binding to Ion Channels. Curr Top Membr. 2017;80:187-208. doi: 10.1016/bs.ctm.2017.05.003. Epub 2017 Jul 27. Review. PubMed PMID: 28863816.

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Bukiya AN, Rosenhouse-Dantsker A. Synergistic activation of G protein-gated inwardly rectifying potassium channels by cholesterol and PI(4,5)P(2). Biochim Biophys Acta Biomembr. 2017 Jul;1859(7):1233-1241. doi: 10.1016/j.bbamem.2017.03.023. Epub 2017 Apr 1. PubMed PMID: 28377218.

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Bukiya AN, Durdagi S, Noskov S, Rosenhouse-Dantsker A. Cholesterol up-regulates neuronal G protein-gated inwardly rectifying potassium (GIRK) channel activity in the hippocampus. J Biol Chem. 2017 Apr 14;292(15):6135-6147. doi: 10.1074/jbc.M116.753350. Epub 2017 Feb 17. PubMed PMID: 28213520; PubMed Central PMCID: PMC5391746.

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Levitan I, Ahn SJ, Fancher I, Rosenhouse-Dantsker A. Physiological roles and cholesterol sensitivity of endothelial inwardly-rectifying K+ channels: specific cholesterol-protein interactions through non annular binding sites. In: Levitan I, Dopico A, editors. Vascular Ion Channels in Physiology and Disease. Switzerland: Springer; 2016. Chapter 15; p.327-347.

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Cheng KT, Rosenhouse-Dantsker A, Malik AB. Contribution and Regulation of Calcium channels in Endothelial Cells. In: Levitan I, Dopico A, editors. Vascular Ion Channels in Physiology and Disease. Switzerland: Springer; 2016. Chapter 2; p.37-62.

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Bukiya AN, Rosenhouse-Dantsker A. Hypercholesterolemia effect on potassium channels. In: Kumar SA, editor. Hypercholesterolemia Croatia: Intech; 2015. Chapter 5; p.95-119.

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Bukiya AN, Osborn CV, Kuntamallappanavar G, Toth PT, Baki L, Kowalsky G, Oh MJ, Dopico AM, Levitan I, Rosenhouse-Dantsker A. Cholesterol increases the open probability of cardiac KACh currents. Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):2406-13. doi: 10.1016/j.bbamem.2015.07.007. Epub 2015 Jul 18. PubMed PMID: 26196595.

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Xu Y, Wang Y, Zhang M, Jiang M, Rosenhouse-Dantsker A, Wassenaar T, Tseng GN. Probing binding sites and mechanisms of action of an I(Ks) activator by computations and experiments. Biophys J. 2015 Jan 6;108(1):62-75. doi: 10.1016/j.bpj.2014.10.059. PubMed PMID: 25564853; PubMed Central PMCID: PMC4286593.

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Rosenhouse-Dantsker A, Epshtein Y, Levitan I. Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2. Comput Struct Biotechnol J. 2014 Sep;11(19):131-7. doi: 10.1016/j.csbj.2014.09.007. eCollection 2014 Sep. PubMed PMID: 25408847; PubMed Central PMCID: PMC4232564.

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Han H, Rosenhouse-Dantsker A, Gnanasambandam R, Epshtein Y, Chen Z, Sachs F, Minshall RD, Levitan I. Silencing of Kir2 channels by caveolin-1: cross-talk with cholesterol. J Physiol. 2014 Sep 15;592(18):4025-38. doi: 10.1113/jphysiol.2014.273177. Epub 2014 Jul 18. PubMed PMID: 25038242; PubMed Central PMCID: PMC4198012.

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Levitan I, Singh DK, Rosenhouse-Dantsker A. Cholesterol binding to ion channels. Front Physiol. 2014;5:65. doi: 10.3389/fphys.2014.00065. eCollection 2014. Review. PubMed PMID: 24616704; PubMed Central PMCID: PMC3935357.

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Rosenhouse-Dantsker A, Noskov S, Durdagi S, Logothetis DE, Levitan I. Identification of novel cholesterol-binding regions in Kir2 channels. J Biol Chem. 2013 Oct 25;288(43):31154-64. doi: 10.1074/jbc.M113.496117. Epub 2013 Sep 9. PubMed PMID: 24019518; PubMed Central PMCID: PMC3829427.

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Rosenhouse-Dantsker A, Noskov S, Logothetis DE, Levitan I. Cholesterol sensitivity of KIR2.1 depends on functional inter-links between the N and C termini. Channels (Austin). 2013 Jul-Aug;7(4):303-12. doi: 10.4161/chan.25437. Epub 2013 Jun 27. PubMed PMID: 23807091; PubMed Central PMCID: PMC3989358.

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Rosenhouse-Dantsker A, Levitan I. Insights into structural determinants of cholesterol sensitivity of Kir channels. In: Levitan I, Barrantes F, editors. Cholesterol regulation of Ion Channels and Receptors. New-Jersey: Wiley-Blackwell; 2012. Chapter 3; p.47-67.

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Rosenhouse-Dantsker A, Noskov S, Han H, Adney SK, Tang QY, Rodríguez-Menchaca AA, Kowalsky GB, Petrou VI, Osborn CV, Logothetis DE, Levitan I. Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)). J Biol Chem. 2012 Nov 23;287(48):40266-78. doi: 10.1074/jbc.M111.336339. Epub 2012 Sep 20. PubMed PMID: 22995912; PubMed Central PMCID: PMC3504743.

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Rodriguez-Menchaca AA, Adney SK, Tang QY, Meng XY, Rosenhouse-Dantsker A, Cui M, Logothetis DE. PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4-S5 linker. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):E2399-408. doi: 10.1073/pnas.1207901109. Epub 2012 Aug 13. PubMed PMID: 22891352; PubMed Central PMCID: PMC3437867.

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Rosenhouse-Dantsker A, Mehta D, Levitan I. Regulation of ion channels by membrane lipids. Compr Physiol. 2012 Jan;2(1):31-68. doi: 10.1002/cphy.c110001. Review. PubMed PMID: 23728970.

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Deng W, Bukiya AN, Rodríguez-Menchaca AA, Zhang Z, Baumgarten CM, Logothetis DE, Levitan I, Rosenhouse-Dantsker A. Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4,5-bisphosphate and Gβγ. J Biol Chem. 2012 Feb 10;287(7):4925-35. doi: 10.1074/jbc.M111.306134. Epub 2011 Dec 15. PubMed PMID: 22174416; PubMed Central PMCID: PMC3281659.

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Rosenhouse-Dantsker A, Logothetis DE, Levitan I. Cholesterol sensitivity of KIR2.1 is controlled by a belt of residues around the cytosolic pore. Biophys J. 2011 Jan 19;100(2):381-9. doi: 10.1016/j.bpj.2010.11.086. PubMed PMID: 21244834; PubMed Central PMCID: PMC3021658.

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Levitan I, Fang Y, Rosenhouse-Dantsker A, Romanenko V. Cholesterol and ion channels. Subcell Biochem. 2010;51:509-49. doi: 10.1007/978-90-481-8622-8_19. Review. PubMed PMID: 20213557; PubMed Central PMCID: PMC2895485.

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Williams DM, Lopes CM, Rosenhouse-Dantsker A, Connelly HL, Matavel A, O-Uchi J, McBeath E, Gray DA. Molecular basis of decreased Kir4.1 function in SeSAME/EAST syndrome. J Am Soc Nephrol. 2010 Dec;21(12):2117-29. doi: 10.1681/ASN.2009121227. Epub 2010 Nov 18. PubMed PMID: 21088294; PubMed Central PMCID: PMC3014025.

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Zhang Z, Rosenhouse-Dantsker A, Tang QY, Noskov S, Logothetis DE. The RCK2 domain uses a coordination site present in Kir channels to confer sodium sensitivity to Slo2.2 channels. J Neurosci. 2010 Jun 2;30(22):7554-62. doi: 10.1523/JNEUROSCI.0525-10.2010. PubMed PMID: 20519529; PubMed Central PMCID: PMC3277328.

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Rosenhouse-Dantsker A, Leal-Pinto E, Logothetis DE, Levitan I. Comparative analysis of cholesterol sensitivity of Kir channels: role of the CD loop. Channels (Austin). 2010 Jan-Feb;4(1):63-6. doi: 10.4161/chan.4.1.10366. Epub 2010 Jan 20. PubMed PMID: 19923917; PubMed Central PMCID: PMC2907253.

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Singh DK, Rosenhouse-Dantsker A, Nichols CG, Enkvetchakul D, Levitan I. Direct regulation of prokaryotic Kir channel by cholesterol. J Biol Chem. 2009 Oct 30;284(44):30727-36. doi: 10.1074/jbc.M109.011221. Epub 2009 Sep 9. PubMed PMID: 19740741; PubMed Central PMCID: PMC2781626.

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Epshtein Y, Chopra AP, Rosenhouse-Dantsker A, Kowalsky GB, Logothetis DE, Levitan I. Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterol. Proc Natl Acad Sci U S A. 2009 May 12;106(19):8055-60. doi: 10.1073/pnas.0809847106. Epub 2009 Apr 29. PubMed PMID: 19416905; PubMed Central PMCID: PMC2683107.

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Rosenhouse-Dantsker A, Sui JL, Zhao Q, Rusinova R, Rodríguez-Menchaca AA, Zhang Z, Logothetis DE. A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P(2). Nat Chem Biol. 2008 Oct;4(10):624-31. doi: 10.1038/nchembio.112. Epub 2008 Sep 14. PubMed PMID: 18794864; PubMed Central PMCID: PMC4100997.

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Jin T, Sui JL, Rosenhouse-Dantsker A, Chan KW, Jan LY, Logothetis DE. Stoichiometry of Kir channels with phosphatidylinositol bisphosphate. Channels (Austin). 2008 Jan-Feb;2(1):19-33. doi: 10.4161/chan.2.1.5942. Epub 2008 Mar 20. PubMed PMID: 18690051.

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Gibor G, Yakubovich D, Rosenhouse-Dantsker A, Peretz A, Schottelndreier H, Seebohm G, Dascal N, Logothetis DE, Paas Y, Attali B. An inactivation gate in the selectivity filter of KCNQ1 potassium channels. Biophys J. 2007 Dec 15;93(12):4159-72. doi: 10.1529/biophysj.107.107987. Epub 2007 Aug 17. PubMed PMID: 17704175; PubMed Central PMCID: PMC2098732.

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Rosenhouse-Dantsker A, Logothetis DE. Molecular characteristics of phosphoinositide binding. Pflugers Arch. 2007 Oct;455(1):45-53. doi: 10.1007/s00424-007-0291-6. Epub 2007 Jun 23. Review. PubMed PMID: 17588168.

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Logothetis DE, Jin T, Lupyan D, Rosenhouse-Dantsker A. Phosphoinositide-mediated gating of inwardly rectifying K(+) channels. Pflugers Arch. 2007 Oct;455(1):83-95. doi: 10.1007/s00424-007-0276-5. Epub 2007 May 23. Review. PubMed PMID: 17520276.

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Logothetis DE, Lupyan D, Rosenhouse-Dantsker A. Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding. J Physiol. 2007 Aug 1;582(Pt 3):953-65. doi: 10.1113/jphysiol.2007.133157. Epub 2007 May 10. Review. PubMed PMID: 17495041; PubMed Central PMCID: PMC2075264.

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Rosenhouse-Dantsker A, Logothetis DE. Potassium channel gating in the absence of the highly conserved glycine of the inner transmembrane helix. Channels (Austin). 2007 May-Jun;1(3):189-97. doi: 10.4161/chan.4475. Epub 2007 May 23. PubMed PMID: 18690025.

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Lopes CM, Remon JI, Matavel A, Sui JL, Keselman I, Medei E, Shen Y, Rosenhouse-Dantsker A, Rohacs T, Logothetis DE. Protein kinase A modulates PLC-dependent regulation and PIP2-sensitivity of K+ channels. Channels (Austin). 2007 Mar-Apr;1(2):124-34. doi: 10.4161/chan.4322. Epub 2007 Apr 23. PubMed PMID: 18690021.