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Kang D, Wahl C, Kim J. Synthesis of push-pull-activated ynol ethers and their evaluation in the bioorthogonal hydroamination reaction. Org Biomol Chem. 2022 Nov 30;20(46):9217-9221. doi: 10.1039/d2ob01917e. PubMed PMID: 36367436; PubMed Central PMCID: PMC9769999.
Kang D, Lee S, Kim J. Bioorthogonal Click and Release: A General, Rapid, Chemically Revertible Bioconjugation Strategy Employing Enamine N-oxides. Chem. 2022 Aug 11;8(8):2260-2277. doi: 10.1016/j.chempr.2022.05.018. Epub 2022 Jun 15. PubMed PMID: 36176744; PubMed Central PMCID: PMC9514142.
Kang D, Cheung ST, Kim J. Bioorthogonal Hydroamination of Push-Pull-Activated Linear Alkynes. Angew Chem Int Ed Engl. 2021 Jul 26;60(31):16947-16952. doi: 10.1002/anie.202104863. Epub 2021 Jun 24. PubMed PMID: 34019705; PubMed Central PMCID: PMC8292212.
Kang D, Cheung ST, Wong-Rolle A, Kim J. Enamine N-Oxides: Synthesis and Application to Hypoxia-Responsive Prodrugs and Imaging Agents. ACS Cent Sci. 2021 Apr 28;7(4):631-640. doi: 10.1021/acscentsci.0c01586. Epub 2021 Mar 29. PubMed PMID: 34056093; PubMed Central PMCID: PMC8155465.
Kang D, Kim J. Bioorthogonal Retro-Cope Elimination Reaction of N,N-Dialkylhydroxylamines and Strained Alkynes. J Am Chem Soc. 2021 Apr 21;143(15):5616-5621. doi: 10.1021/jacs.1c00885. Epub 2021 Apr 8. PubMed PMID: 33829777; PubMed Central PMCID: PMC8483621.
Hu JJ, Liu X, Xia S, Zhang Z, Zhang Y, Zhao J, Ruan J, Luo X, Lou X, Bai Y, Wang J, Hollingsworth LR, Magupalli VG, Zhao L, Luo HR, Kim J, Lieberman J, Wu H. FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation. Nat Immunol. 2020 Jul;21(7):736-745. doi: 10.1038/s41590-020-0669-6. Epub 2020 May 4. PubMed PMID: 32367036; PubMed Central PMCID: PMC7316630.
Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, Bassik MC, Aigner L, Wyss-Coray T. Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. Nat Neurosci. 2020 Feb;23(2):194-208. doi: 10.1038/s41593-019-0566-1. Epub 2020 Jan 20. PubMed PMID: 31959936; PubMed Central PMCID: PMC7595134.
Haines BE, Nelson BM, Grandner JM, Kim J, Houk KN, Movassaghi M, Musaev DG. Mechanism of Permanganate-Promoted Dihydroxylation of Complex Diketopiperazines: Critical Roles of Counter-cation and Ion-Pairing. J Am Chem Soc. 2018 Oct 17;140(41):13375-13386. doi: 10.1021/jacs.8b08371. Epub 2018 Oct 8. PubMed PMID: 30295476; PubMed Central PMCID: PMC6209109.
Kim J, Bertozzi CR. A Bioorthogonal Reaction of N-Oxide and Boron Reagents. Angew Chem Int Ed Engl. 2015 Dec 21;54(52):15777-81. doi: 10.1002/anie.201508861. Epub 2015 Nov 16. PubMed PMID: 26568479; PubMed Central PMCID: PMC4715665.
Kim J, Movassaghi M. Biogenetically-inspired total synthesis of epidithiodiketopiperazines and related alkaloids. Acc Chem Res. 2015 Apr 21;48(4):1159-71. doi: 10.1021/ar500454v. Epub 2015 Apr 6. PubMed PMID: 25843276; PubMed Central PMCID: PMC4408872.
Yang G, Lindovska P, Zhu D, Kim J, Wang P, Tang RY, Movassaghi M, Yu JQ. Pd(II)-catalyzed meta-C-H olefination, arylation, and acetoxylation of indolines using a U-shaped template. J Am Chem Soc. 2014 Jul 30;136(30):10807-13. doi: 10.1021/ja505737x. Epub 2014 Jul 22. PubMed PMID: 25007097.
Compounds, Conjugates and Compositions of Epipolythiodiketopiperazines and Polythiodiketopiperazines. US patent application 14/096,158. 2013 December.
Coste A, Kim J, Adams TC, Movassaghi M. Concise Total Synthesis of (+)-Bionectins A and C. Chem Sci. 2013 Aug;4(8):3191-3197. doi: 10.1039/C3SC51150B. PubMed PMID: 23878720; PubMed Central PMCID: PMC3713796.
Boyer N, Morrison KC, Kim J, Hergenrother PJ, Movassaghi M. Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids. Chem Sci. 2013 Apr 1;4(4):1646-1657. doi: 10.1039/C3SC50174D. PubMed PMID: 23914293; PubMed Central PMCID: PMC3728915.
Kim J, Movassaghi M. (+)-11,11'-Dideoxyverticillin A. In: Li JJ, Corey EJ, editors. Total Synthesis of Natural Products Berlin Heidelberg: Springer; 2012. Chapter 9; p.211-233. 279p.
Lathrop SP, Kim J, Movassaghi M. Radical-mediated dimerization and oxidation reactions for the synthesis of complex alkaloids. Chimia (Aarau). 2012;66(6):389-93. doi: 10.2533/chimia.2012.389. Review. PubMed PMID: 22871281; PubMed Central PMCID: PMC3507436.
Kim J, Movassaghi M. Concise total synthesis and stereochemical revision of (+)-naseseazines A and B: regioselective arylative dimerization of diketopiperazine alkaloids. J Am Chem Soc. 2011 Sep 28;133(38):14940-3. doi: 10.1021/ja206743v. Epub 2011 Sep 2. PubMed PMID: 21875056; PubMed Central PMCID: PMC3369503.
Kim J, Movassaghi M. General approach to epipolythiodiketopiperazine alkaloids: total synthesis of (+)-chaetocins A and C and (+)-12,12'-dideoxychetracin A. J Am Chem Soc. 2010 Oct 20;132(41):14376-8. doi: 10.1021/ja106869s. PubMed PMID: 20866039; PubMed Central PMCID: PMC2987664.
Kim J, Movassaghi M. Biogenetically inspired syntheses of alkaloid natural products. Chem Soc Rev. 2009 Nov;38(11):3035-50. doi: 10.1039/b819925f. Epub 2009 Sep 23. Review. PubMed PMID: 19847339.
Kim J, Ashenhurst JA, Movassaghi M. Total synthesis of (+)-11,11'-dideoxyverticillin A. Science. 2009 Apr 10;324(5924):238-41. doi: 10.1126/science.1170777. PubMed PMID: 19359584; PubMed Central PMCID: PMC4238916.
Kim J, Thomson RJ. Enantioselective total synthesis of the osteoclastogenesis inhibitor (+)-symbioimine. Angew Chem Int Ed Engl. 2007;46(17):3104-6. doi: 10.1002/anie.200605160. PubMed PMID: 17366505.
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