My Bibliography

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Vukovich MJ, Shiakolas AR, Lindenberger J, Richardson RA, Bass LE, Barr M, Liu Y, Go EP, Park CS, May AJ, Sammour S, Kambarami C, Huang X, Janowska K, Edwards RJ, Mansouri K, Spence TN, Abu-Shmais AA, Manamela NP, Richardson SI, Leonard SEW, Gripenstraw KR, Setliff I, Saunders KO, Bonami RH, Ross TM, Desaire H, Moore PL, Parks R, Haynes BF, Sheward DJ, Acharya P, Sautto GA, Georgiev IS. Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral families. PLoS Pathog. 2024 Sep;20(9):e1012499. doi: 10.1371/journal.ppat.1012499. eCollection 2024 Sep. PubMed PMID: 39292703; PubMed Central PMCID: PMC11410209.

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Obare LM, Bonami RH, Doran AC, Wanjalla CN. B cells and atherosclerosis: A HIV perspective. J Cell Physiol. 2024 Jun;239(6):e31270. doi: 10.1002/jcp.31270. Epub 2024 Apr 23. Review. PubMed PMID: 38651687; PubMed Central PMCID: PMC11209796.

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Bass LE, Bonami RH. Factors Governing B Cell Recognition of Autoantigen and Function in Type 1 Diabetes. Antibodies (Basel). 2024 Apr 1;13(2). doi: 10.3390/antib13020027. Review. PubMed PMID: 38651407; PubMed Central PMCID: PMC11036271.

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Alleva DG, Delpero AR, Sathiyaseelan T, Murikipudi S, Lancaster TM, Atkinson MA, Wasserfall CH, Yu L, Ragupathy R, Bonami RH, Zion TC. An antigen-specific immunotherapeutic, AKS-107, deletes insulin-specific B cells and prevents murine autoimmune diabetes. Front Immunol. 2024;15:1367514. doi: 10.3389/fimmu.2024.1367514. eCollection 2024. PubMed PMID: 38515750; PubMed Central PMCID: PMC10954819.

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McNitt DH, Joosse BA, Thomas JW, Bonami RH. Productive Germinal Center Responses Depend on the Nature of Stimuli Received by Anti-Insulin B Cells in Type 1 Diabetes-Prone Mice. Immunohorizons. 2023 Jun 1;7(6):384-397. doi: 10.4049/immunohorizons.2300036. PubMed PMID: 37261716; PubMed Central PMCID: PMC10448785.

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Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker LM, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE Jr, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine. Nat Commun. 2022 Jun 16;13(1):3466. doi: 10.1038/s41467-022-31142-5. PubMed PMID: 35710908; PubMed Central PMCID: PMC9201272.

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Wilfong EM, Vowell KN, Bunn KE, Rizzi E, Annapureddy N, Dudenhofer RB, Barnado A, Bonami RH, Johnson JE, Crofford LJ, Kendall PL. CD19 + CD21(lo/neg) cells are increased in systemic sclerosis-associated interstitial lung disease. Clin Exp Med. 2022 May;22(2):209-220. doi: 10.1007/s10238-021-00745-5. Epub 2021 Aug 10. PubMed PMID: 34374937; PubMed Central PMCID: PMC8828801.

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Bonami RH, Thurman CE, Verma S, Westlake CS, Nyhoff LE, Barron BB, Reboldi A, Kendall PL. Bruton's Tyrosine Kinase Supports Gut Mucosal Immunity and Commensal Microbiome Recognition in Autoimmune Arthritis. Front Immunol. 2022;13:748284. doi: 10.3389/fimmu.2022.748284. eCollection 2022. PubMed PMID: 35422819; PubMed Central PMCID: PMC9002138.

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Wilfong EM, Bartkowiak T, Vowell KN, Westlake CS, Irish JM, Kendall PL, Crofford LJ, Bonami RH. High-Dimensional Analysis Reveals Distinct Endotypes in Patients With Idiopathic Inflammatory Myopathies. Front Immunol. 2022;13:756018. doi: 10.3389/fimmu.2022.756018. eCollection 2022. PubMed PMID: 35371068; PubMed Central PMCID: PMC8964392.

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Nyhoff LE, Griffith AS, Clark ES, Thomas JW, Khan WN, Kendall PL. Btk Supports Autoreactive B Cell Development and Protects against Apoptosis but Is Expendable for Antigen Presentation. J Immunol. 2021 Dec 15;207(12):2922-2932. doi: 10.4049/jimmunol.2000558. Epub 2021 Nov 19. PubMed PMID: 34799428; PubMed Central PMCID: PMC9117567.

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Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker L, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine. bioRxiv. 2021 Jul 28;. doi: 10.1101/2021.07.28.453981. PubMed PMID: 34341788; PubMed Central PMCID: PMC8328055.

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Joosse BA, Jackson JH, Cisneros A, Santhin AB, Smith SA, Moore DJ, Crofford LJ, Wilfong EM, Bonami RH. High-Throughput Detection of Autoantigen-Specific B Cells Among Distinct Functional Subsets in Autoimmune Donors. Front Immunol. 2021;12:685718. doi: 10.3389/fimmu.2021.685718. eCollection 2021. PubMed PMID: 34234784; PubMed Central PMCID: PMC8256427.

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Young-Glazer J, Cisneros A 3rd, Wilfong EM, Smith SA, Crofford LJ, Bonami RH. Jo-1 autoantigen-specific B cells are skewed towards distinct functional B cell subsets in anti-synthetase syndrome patients. Arthritis Res Ther. 2021 Jan 19;23(1):33. doi: 10.1186/s13075-020-02412-8. PubMed PMID: 33468230; PubMed Central PMCID: PMC7814460.

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Felton JL, Conway H, Bonami RH. B Quiet: Autoantigen-Specific Strategies to Silence Raucous B Lymphocytes and Halt Cross-Talk with T Cells in Type 1 Diabetes. Biomedicines. 2021 Jan 6;9(1). doi: 10.3390/biomedicines9010042. Review. PubMed PMID: 33418839; PubMed Central PMCID: PMC7824835.

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Bonami RH, Nyhoff LE, McNitt DH, Hulbert C, Felton JL, Kendall PL, Thomas JW. T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein. J Immunol. 2020 Dec 15;205(12):3263-3276. doi: 10.4049/jimmunol.1900464. Epub 2020 Nov 16. PubMed PMID: 33199538; PubMed Central PMCID: PMC7725913.

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Jackson MA, Bedingfield SK, Yu F, Stokan ME, Miles RE, Curvino EJ, Hoogenboezem EN, Bonami RH, Patel SS, Kendall PL, Giorgio TD, Duvall CL. Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes. Biomaterials. 2019 Feb;192:245-259. doi: 10.1016/j.biomaterials.2018.11.010. Epub 2018 Nov 10. PubMed PMID: 30458360; PubMed Central PMCID: PMC6534819.

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Wilson CS, Chhabra P, Marshall AF, Morr CV, Stocks BT, Hoopes EM, Bonami RH, Poffenberger G, Brayman KL, Moore DJ. Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice. Diabetes. 2018 Nov;67(11):2349-2360. doi: 10.2337/db18-0456. Epub 2018 Aug 21. PubMed PMID: 30131391; PubMed Central PMCID: PMC6198348.

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Felton JL, Maseda D, Bonami RH, Hulbert C, Thomas JW. Anti-Insulin B Cells Are Poised for Antigen Presentation in Type 1 Diabetes. J Immunol. 2018 Aug 1;201(3):861-873. doi: 10.4049/jimmunol.1701717. Epub 2018 Jun 27. PubMed PMID: 29950508; PubMed Central PMCID: PMC7029791.

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Nyhoff LE, Clark ES, Barron BL, Bonami RH, Khan WN, Kendall PL. Bruton's Tyrosine Kinase Is Not Essential for B Cell Survival beyond Early Developmental Stages. J Immunol. 2018 Apr 1;200(7):2352-2361. doi: 10.4049/jimmunol.1701489. Epub 2018 Feb 26. PubMed PMID: 29483358; PubMed Central PMCID: PMC6177684.

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Nyhoff LE, Barron BL, Johnson EM, Bonami RH, Maseda D, Fensterheim BA, Han W, Blackwell TS, Crofford LJ, Kendall PL. Bruton's Tyrosine Kinase Deficiency Inhibits Autoimmune Arthritis in Mice but Fails to Block Immune Complex-Mediated Inflammatory Arthritis. Arthritis Rheumatol. 2016 Aug;68(8):1856-68. doi: 10.1002/art.39657. PubMed PMID: 26945549; PubMed Central PMCID: PMC5668904.

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Itani HA, McMaster WG Jr, Saleh MA, Nazarewicz RR, Mikolajczyk TP, Kaszuba AM, Konior A, Prejbisz A, Januszewicz A, Norlander AE, Chen W, Bonami RH, Marshall AF, Poffenberger G, Weyand CM, Madhur MS, Moore DJ, Harrison DG, Guzik TJ. Activation of Human T Cells in Hypertension: Studies of Humanized Mice and Hypertensive Humans. Hypertension. 2016 Jul;68(1):123-32. doi: 10.1161/HYPERTENSIONAHA.116.07237. Epub 2016 May 23. PubMed PMID: 27217403; PubMed Central PMCID: PMC4900908.

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Bonami RH, Thomas JW. Targeting Anti-Insulin B Cell Receptors Improves Receptor Editing in Type 1 Diabetes-Prone Mice. J Immunol. 2015 Nov 15;195(10):4730-41. doi: 10.4049/jimmunol.1500438. Epub 2015 Oct 2. PubMed PMID: 26432895; PubMed Central PMCID: PMC4637270.

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Williams JM, Bonami RH, Hulbert C, Thomas JW. Reversing Tolerance in Isotype Switch-Competent Anti-Insulin B Lymphocytes. J Immunol. 2015 Aug 1;195(3):853-64. doi: 10.4049/jimmunol.1403114. Epub 2015 Jun 24. PubMed PMID: 26109644; PubMed Central PMCID: PMC4506889.

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Case JB, Bonami RH, Nyhoff LE, Steinberg HE, Sullivan AM, Kendall PL. Bruton's Tyrosine Kinase Synergizes with Notch2 To Govern Marginal Zone B Cells in Nonobese Diabetic Mice. J Immunol. 2015 Jul 1;195(1):61-70. doi: 10.4049/jimmunol.1400803. Epub 2015 Jun 1. PubMed PMID: 26034172; PubMed Central PMCID: PMC4551465.

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Bonami RH, Wolfle WT, Thomas JW, Kendall PL. NFATc2 (NFAT1) assists BCR-mediated anergy in anti-insulin B cells. Mol Immunol. 2014 Dec;62(2):321-8. doi: 10.1016/j.molimm.2014.01.003. Epub 2014 Feb 6. PubMed PMID: 24507801; PubMed Central PMCID: PMC4125564.

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Maseda D, Bonami RH, Crofford LJ. Regulation of B lymphocytes and plasma cells by innate immune mechanisms and stromal cells in rheumatoid arthritis. Expert Rev Clin Immunol. 2014 Jun;10(6):747-62. doi: 10.1586/1744666X.2014.907744. Epub 2014 Apr 16. Review. PubMed PMID: 24734886; PubMed Central PMCID: PMC5073792.

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Bonami RH, Sullivan AM, Case JB, Steinberg HE, Hoek KL, Khan WN, Kendall PL. Bruton's tyrosine kinase promotes persistence of mature anti-insulin B cells. J Immunol. 2014 Feb 15;192(4):1459-70. doi: 10.4049/jimmunol.1300125. Epub 2014 Jan 22. PubMed PMID: 24453243; PubMed Central PMCID: PMC4083749.

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Henry-Bonami RA, Williams JM, Rachakonda AB, Karamali M, Kendall PL, Thomas JW. B lymphocyte "original sin" in the bone marrow enhances islet autoreactivity in type 1 diabetes-prone nonobese diabetic mice. J Immunol. 2013 Jun 15;190(12):5992-6003. doi: 10.4049/jimmunol.1201359. Epub 2013 May 15. PubMed PMID: 23677466; PubMed Central PMCID: PMC3679359.

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Henry RA, Kendall PL, Thomas JW. Autoantigen-specific B-cell depletion overcomes failed immune tolerance in type 1 diabetes. Diabetes. 2012 Aug;61(8):2037-44. doi: 10.2337/db11-1746. Epub 2012 Jun 14. PubMed PMID: 22698916; PubMed Central PMCID: PMC3402296.

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Henry RA, Kendall PL, Woodward EJ, Hulbert C, Thomas JW. Vkappa polymorphisms in NOD mice are spread throughout the entire immunoglobulin kappa locus and are shared by other autoimmune strains. Immunogenetics. 2010 Aug;62(8):507-20. doi: 10.1007/s00251-010-0457-9. Epub 2010 Jun 17. PubMed PMID: 20556377; PubMed Central PMCID: PMC2970566.

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Henry RA, Kendall PL. CXCL13 blockade disrupts B lymphocyte organization in tertiary lymphoid structures without altering B cell receptor bias or preventing diabetes in nonobese diabetic mice. J Immunol. 2010 Aug 1;185(3):1460-5. doi: 10.4049/jimmunol.0903710. Epub 2010 Jun 23. PubMed PMID: 20574003; PubMed Central PMCID: PMC3824617.

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Henry RA, Acevedo-Suárez CA, Thomas JW. Functional silencing is initiated and maintained in immature anti-insulin B cells. J Immunol. 2009 Mar 15;182(6):3432-9. doi: 10.4049/jimmunol.0803121. PubMed PMID: 19265121; PubMed Central PMCID: PMC3845364.

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Antar AA, Konopka JL, Campbell JA, Henry RA, Perdigoto AL, Carter BD, Pozzi A, Abel TW, Dermody TS. Junctional adhesion molecule-A is required for hematogenous dissemination of reovirus. Cell Host Microbe. 2009 Jan 22;5(1):59-71. doi: 10.1016/j.chom.2008.12.001. PubMed PMID: 19154988; PubMed Central PMCID: PMC2642927.

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Kendall PL, Yu G, Woodward EJ, Thomas JW. Tertiary lymphoid structures in the pancreas promote selection of B lymphocytes in autoimmune diabetes. J Immunol. 2007 May 1;178(9):5643-51. doi: 10.4049/jimmunol.178.9.5643. PubMed PMID: 17442947; NIHMSID:NIHMS527654.