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Zhao J, Townsend KL, Schulz LC, Kunz TH, Li C, Widmaier EP. Leptin receptor expression increases in placenta, but not hypothalamus, during gestation in Mus musculus and Myotis lucifugus. Placenta. 2004 Sep-Oct;25(8-9):712-22. doi: 10.1016/j.placenta.2004.01.017. PubMed PMID: 15450389.
Schulz LC, Townsend K, Kunz TH, Widmaier EP. Inhibition of trophoblast invasiveness in vitro by immunoneutralization of leptin in the bat, Myotis lucifugus (Chiroptera). Gen Comp Endocrinol. 2007 Jan 1;150(1):59-65. doi: 10.1016/j.ygcen.2006.07.007. Epub 2006 Aug 30. PubMed PMID: 16938297.
Townsend KL, Kunz TH, Widmaier EP. Changes in body mass, serum leptin, and mRNA levels of leptin receptor isoforms during the premigratory period in Myotis lucifugus. J Comp Physiol B. 2008 Feb;178(2):217-23. doi: 10.1007/s00360-007-0215-y. Epub 2007 Oct 26. PubMed PMID: 17962952.
Townsend KL, Lorenzi MM, Widmaier EP. High-fat diet-induced changes in body mass and hypothalamic gene expression in wild-type and leptin-deficient mice. Endocrine. 2008 Apr;33(2):176-88. doi: 10.1007/s12020-008-9070-1. Epub 2008 May 16. PubMed PMID: 18483882.
Schulz TJ, Huang TL, Tran TT, Zhang H, Townsend KL, Shadrach JL, Cerletti M, McDougall LE, Giorgadze N, Tchkonia T, Schrier D, Falb D, Kirkland JL, Wagers AJ, Tseng YH. Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):143-8. doi: 10.1073/pnas.1010929108. Epub 2010 Dec 20. PubMed PMID: 21173238; PubMed Central PMCID: PMC3017184.
Townsend K, Tseng YH. Brown adipose tissue: Recent insights into development, metabolic function and therapeutic potential. Adipocyte. 2012 Jan 1;1(1):13-24. doi: 10.4161/adip.18951. PubMed PMID: 23700507; PubMed Central PMCID: PMC3661118.
Townsend KL, Suzuki R, Huang TL, Jing E, Schulz TJ, Lee K, Taniguchi CM, Espinoza DO, McDougall LE, Zhang H, He TC, Kokkotou E, Tseng YH. Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway. FASEB J. 2012 May;26(5):2187-96. doi: 10.1096/fj.11-199067. Epub 2012 Feb 13. PubMed PMID: 22331196; PubMed Central PMCID: PMC3336788.
Stanford KI, Middelbeek RJ, Townsend KL, An D, Nygaard EB, Hitchcox KM, Markan KR, Nakano K, Hirshman MF, Tseng YH, Goodyear LJ. Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. J Clin Invest. 2013 Jan;123(1):215-23. doi: 10.1172/JCI62308. Epub 2012 Dec 10. PubMed PMID: 23221344; PubMed Central PMCID: PMC3533266.
Liew CW, Boucher J, Cheong JK, Vernochet C, Koh HJ, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng YH, Hellerstein MK, Farmer SR, Goodyear L, Doria A, Blüher M, Hsu SI, Kulkarni RN. Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nat Med. 2013 Feb;19(2):217-26. doi: 10.1038/nm.3056. Epub 2013 Jan 6. PubMed PMID: 23291629; PubMed Central PMCID: PMC3567215.
Schulz TJ, Huang P, Huang TL, Xue R, McDougall LE, Townsend KL, Cypess AM, Mishina Y, Gussoni E, Tseng YH. Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat. Nature. 2013 Mar 21;495(7441):379-83. doi: 10.1038/nature11943. Epub 2013 Mar 13. PubMed PMID: 23485971; PubMed Central PMCID: PMC3623555.
Townsend KL, An D, Lynes MD, Huang TL, Zhang H, Goodyear LJ, Tseng YH. Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake. Antioxid Redox Signal. 2013 Jul 20;19(3):243-57. doi: 10.1089/ars.2012.4536. Epub 2012 Oct 9. PubMed PMID: 22938691; PubMed Central PMCID: PMC3691916.
Townsend KL, Tseng YH. Brown fat fuel utilization and thermogenesis. Trends Endocrinol Metab. 2014 Apr;25(4):168-77. doi: 10.1016/j.tem.2013.12.004. Epub 2014 Jan 2. Review. PubMed PMID: 24389130; PubMed Central PMCID: PMC3972344.
Townsend KL, Tseng Y. Of Mice and Men: Novel Insights Regarding Constitutive and Recuitable Brown Adipocytes. International Journal of Obesity Supplements. 2015; 5:S15-20.
Stanford KI, Middelbeek RJ, Townsend KL, Lee MY, Takahashi H, So K, Hitchcox KM, Markan KR, Hellbach K, Hirshman MF, Tseng YH, Goodyear LJ. A novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis. Diabetes. 2015 Jun;64(6):2002-14. doi: 10.2337/db14-0704. Epub 2015 Jan 20. PubMed PMID: 25605808; PubMed Central PMCID: PMC4439563.
Xue R, Lynes MD, Dreyfuss JM, Shamsi F, Schulz TJ, Zhang H, Huang TL, Townsend KL, Li Y, Takahashi H, Weiner LS, White AP, Lynes MS, Rubin LL, Goodyear LJ, Cypess AM, Tseng YH. Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes. Nat Med. 2015 Jul;21(7):760-8. doi: 10.1038/nm.3881. Epub 2015 Jun 15. PubMed PMID: 26076036; PubMed Central PMCID: PMC4496292.
Zhang H, Guan M, Townsend KL, Huang TL, An D, Yan X, Xue R, Schulz TJ, Winnay J, Mori M, Hirshman MF, Kristiansen K, Tsang JS, White AP, Cypess AM, Goodyear LJ, Tseng YH. MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1α signaling network. EMBO Rep. 2015 Oct;16(10):1378-93. doi: 10.15252/embr.201540837. Epub 2015 Aug 24. PubMed PMID: 26303948; PubMed Central PMCID: PMC4766451.
Blaszkiewicz M, Townsend KL. Adipose Tissue and Energy Expenditure: Central and Peripheral Neural Activation Pathways. Curr Obes Rep. 2016 Jun;5(2):241-50. doi: 10.1007/s13679-016-0216-9. Review. PubMed PMID: 27055864.
Townsend KL, Madden CJ, Blaszkiewicz M, McDougall L, Tupone D, Lynes MD, Mishina Y, Yu P, Morrison SF, Tseng YH. Reestablishment of Energy Balance in a Male Mouse Model With POMC Neuron Deletion of BMPR1A. Endocrinology. 2017 Dec 1;158(12):4233-4245. doi: 10.1210/en.2017-00212. PubMed PMID: 29040444; PubMed Central PMCID: PMC5711385.
Waldron AL, Schroder PA, Bourgon KL, Bolduc JK, Miller JL, Pellegrini AD, Dubois AL, Blaszkiewicz M, Townsend KL, Rieger S. Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity. J Diabetes Complications. 2018 Mar;32(3):249-257. doi: 10.1016/j.jdiacomp.2017.11.012. Epub 2017 Dec 6. PubMed PMID: 29306589; PubMed Central PMCID: PMC5820202.
Miller JL, Blaszkiewicz M, Beaton C, Johnson CP, Waible S 2nd, Dubois AL, Klemmer A, Kiebish M, Townsend KL. A peroxidized omega-3-enriched polyunsaturated diet leads to adipose and metabolic dysfunction. J Nutr Biochem. 2019 Feb;64:50-60. doi: 10.1016/j.jnutbio.2018.10.010. Epub 2018 Oct 26. PubMed PMID: 30439568.
Blaszkiewicz M, Willows JW, Johnson CP, Townsend KL. The Importance of Peripheral Nerves in Adipose Tissue for the Regulation of Energy Balance. Biology (Basel). 2019 Feb 12;8(1). doi: 10.3390/biology8010010. Review. PubMed PMID: 30759876; PubMed Central PMCID: PMC6466238.
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