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Li L, Pulver SR, Kelley WP, Thirumalai V, Sweedler JV, Marder E. Orcokinin peptides in developing and adult crustacean stomatogastric nervous systems and pericardial organs. J Comp Neurol. 2002 Mar 12;444(3):227-44. doi: 10.1002/cne.10139. PubMed PMID: 11840477.
Masselon C, Pasa-Tolić L, Lee SW, Li L, Anderson GA, Harkewicz R, Smith RD. Identification of tryptic peptides from large databases using multiplexed tandem mass spectrometry: simulations and experimental results. Proteomics. 2003 Jul;3(7):1279-86. doi: 10.1002/pmic.200300448. PubMed PMID: 12872228.
Li L, Kelley WP, Billimoria CP, Christie AE, Pulver SR, Sweedler JV, Marder E. Mass spectrometric investigation of the neuropeptide complement and release in the pericardial organs of the crab, Cancer borealis. J Neurochem. 2003 Nov;87(3):642-56. doi: 10.1046/j.1471-4159.2003.02031.x. PubMed PMID: 14535947.
Kutz KK, Schmidt JJ, Li L. In situ tissue analysis of neuropeptides by MALDI FTMS in-cell accumulation. Anal Chem. 2004 Oct 1;76(19):5630-40. doi: 10.1021/ac049255b. PubMed PMID: 15456280.
Yew JY, Kutz KK, Dikler S, Messinger L, Li L, Stretton AO. Mass spectrometric map of neuropeptide expression in Ascaris suum. J Comp Neurol. 2005 Aug 8;488(4):396-413. doi: 10.1002/cne.20587. PubMed PMID: 15973679.
Messinger DI, Kutz KK, Le T, Verley DR, Hsu YW, Ngo CT, Cain SD, Birmingham JT, Li L, Christie AE. Identification and characterization of a tachykinin-containing neuroendocrine organ in the commissural ganglion of the crab Cancer productus. J Exp Biol. 2005 Sep;208(Pt 17):3303-19. doi: 10.1242/jeb.01787. PubMed PMID: 16109892.
Billimoria CP, Li L, Marder E. Profiling of neuropeptides released at the stomatogastric ganglion of the crab, Cancer borealis with mass spectrometry. J Neurochem. 2005 Oct;95(1):191-9. doi: 10.1111/j.1471-4159.2005.03355.x. PubMed PMID: 16181423.
Proekt A, Vilim FS, Alexeeva V, Brezina V, Friedman A, Jing J, Li L, Zhurov Y, Sweedler JV, Weiss KR. Identification of a new neuropeptide precursor reveals a novel source of extrinsic modulation in the feeding system of Aplysia. J Neurosci. 2005 Oct 19;25(42):9637-48. doi: 10.1523/JNEUROSCI.2932-05.2005. PubMed PMID: 16237168; PubMed Central PMCID: PMC6725720.
Fu Q, Christie AE, Li L. Mass spectrometric characterization of crustacean hyperglycemic hormone precursor-related peptides (CPRPs) from the sinus gland of the crab, Cancer productus. Peptides. 2005 Nov;26(11):2137-50. doi: 10.1016/j.peptides.2005.03.040. Epub 2005 Apr 21. PubMed PMID: 16269349.
Fu Q, Goy MF, Li L. Identification of neuropeptides from the decapod crustacean sinus glands using nanoscale liquid chromatography tandem mass spectrometry. Biochem Biophys Res Commun. 2005 Nov 25;337(3):765-78. doi: 10.1016/j.bbrc.2005.09.111. Epub 2005 Sep 28. PubMed PMID: 16214114.
Fu Q, Kutz KK, Schmidt JJ, Hsu YW, Messinger DI, Cain SD, de la Iglesia HO, Christie AE, Li L. Hormone complement of the Cancer productus sinus gland and pericardial organ: an anatomical and mass spectrometric investigation. J Comp Neurol. 2005 Dec 26;493(4):607-26. doi: 10.1002/cne.20773. PubMed PMID: 16304631.
Fu Q, Li L. Investigation of several unique tandem mass spectrometric fragmentation patterns of NFDEIDR, an orcokinin analog, and its N-terminal dimethylated form. Rapid Commun Mass Spectrom. 2006;20(4):553-62. doi: 10.1002/rcm.2337. PubMed PMID: 16419022.
DeKeyser SS, Li L. Matrix-assisted laser desorption/ionization Fourier transform mass spectrometry quantitation via in cell combination. Analyst. 2006 Feb;131(2):281-90. doi: 10.1039/b510831d. Epub 2005 Nov 28. PubMed PMID: 16440095.
Cruz-Bermúdez ND, Fu Q, Kutz-Naber KK, Christie AE, Li L, Marder E. Mass spectrometric characterization and physiological actions of GAHKNYLRFamide, a novel FMRFamide-like peptide from crabs of the genus Cancer. J Neurochem. 2006 May;97(3):784-99. doi: 10.1111/j.1471-4159.2006.03747.x. Epub 2006 Mar 3. PubMed PMID: 16515542.
Fu Q, Li L. Fragmentation of peptides with N-terminal dimethylation and imine/methylol adduction at the tryptophan side-chain. J Am Soc Mass Spectrom. 2006 Jun;17(6):859-866. doi: 10.1016/j.jasms.2006.03.002. Epub 2006 Apr 17. PubMed PMID: 16616858.
Dowell JA, Heyden WV, Li L. Rat neuropeptidomics by LC-MS/MS and MALDI-FTMS: Enhanced dissection and extraction techniques coupled with 2D RP-RP HPLC. J Proteome Res. 2006 Dec;5(12):3368-75. doi: 10.1021/pr0603452. PubMed PMID: 17137338.
Fu Q, Li L. Neutral loss of water from the b ions with histidine at the C-terminus and formation of the c ions involving lysine side chains. J Mass Spectrom. 2006 Dec;41(12):1600-7. doi: 10.1002/jms.1061. PubMed PMID: 16830357.
DeKeyser SS, Li L. Mass spectrometric charting of neuropeptides in arthropod neurons. Anal Bioanal Chem. 2007 Jan;387(1):29-35. doi: 10.1007/s00216-006-0596-x. PubMed PMID: 16955266.
Saideman SR, Ma M, Kutz-Naber KK, Cook A, Torfs P, Schoofs L, Li L, Nusbaum MP. Modulation of rhythmic motor activity by pyrokinin peptides. J Neurophysiol. 2007 Jan;97(1):579-95. doi: 10.1152/jn.00772.2006. Epub 2006 Oct 25. PubMed PMID: 17065249.
Ma M, Kutz-Naber KK, Li L. Methyl esterification assisted MALDI FTMS characterization of the orcokinin neuropeptide family. Anal Chem. 2007 Jan 15;79(2):673-81. doi: 10.1021/ac061536r. PubMed PMID: 17222036.
Christie AE, Kutz-Naber KK, Stemmler EA, Klein A, Messinger DI, Goiney CC, Conterato AJ, Bruns EA, Hsu YW, Li L, Dickinson PS. Midgut epithelial endocrine cells are a rich source of the neuropeptides APSGFLGMRamide (Cancer borealis tachykinin-related peptide Ia) and GYRKPPFNGSIFamide (Gly1-SIFamide) in the crabs Cancer borealis, Cancer magister and Cancer productus. J Exp Biol. 2007 Feb;210(Pt 4):699-714. doi: 10.1242/jeb.02696. PubMed PMID: 17267655.
Fu Q, Tang LS, Marder E, Li L. Mass spectrometric characterization and physiological actions of VPNDWAHFRGSWamide, a novel B type allatostatin in the crab, Cancer borealis. J Neurochem. 2007 May;101(4):1099-107. doi: 10.1111/j.1471-4159.2007.04482.x. Epub 2007 Mar 29. PubMed PMID: 17394556.
DeKeyser SS, Kutz-Naber KK, Schmidt JJ, Barrett-Wilt GA, Li L. Imaging mass spectrometry of neuropeptides in decapod crustacean neuronal tissues. J Proteome Res. 2007 May;6(5):1782-91. doi: 10.1021/pr060603v. Epub 2007 Mar 24. PubMed PMID: 17381149; PubMed Central PMCID: PMC2529365.
Li L, Sweedler JV. Peptides in the brain: mass spectrometry-based measurement approaches and challenges. Annu Rev Anal Chem (Palo Alto Calif). 2008;1:451-83. doi: 10.1146/annurev.anchem.1.031207.113053. Review. PubMed PMID: 20636086.
Wang J, Chen R, Ma M, Li L. MALDI MS sample preparation by using paraffin wax film: systematic study and application for peptide analysis. Anal Chem. 2008 Jan 15;80(2):491-500. doi: 10.1021/ac701614f. PubMed PMID: 18189446.
Schmidt JJ, McIlwain S, Page D, Christie AE, Li L. Combining MALDI-FTMS and bioinformatics for rapid peptidomic comparisons. J Proteome Res. 2008 Mar;7(3):887-96. doi: 10.1021/pr070390p. Epub 2008 Jan 19. PubMed PMID: 18205299.
Christie AE, Cashman CR, Brennan HR, Ma M, Sousa GL, Li L, Stemmler EA, Dickinson PS. Identification of putative crustacean neuropeptides using in silico analyses of publicly accessible expressed sequence tags. Gen Comp Endocrinol. 2008 Apr 1;156(2):246-64. doi: 10.1016/j.ygcen.2008.01.018. Epub 2008 Jan 31. PubMed PMID: 18321503.
Ma M, Chen R, Sousa GL, Bors EK, Kwiatkowski MA, Goiney CC, Goy MF, Christie AE, Li L. Mass spectral characterization of peptide transmitters/hormones in the nervous system and neuroendocrine organs of the American lobster Homarus americanus. Gen Comp Endocrinol. 2008 Apr 1;156(2):395-409. doi: 10.1016/j.ygcen.2008.01.009. Epub 2008 Jan 26. PubMed PMID: 18304551; PubMed Central PMCID: PMC2293973.
Cape SS, Rehm KJ, Ma M, Marder E, Li L. Mass spectral comparison of the neuropeptide complement of the stomatogastric ganglion and brain in the adult and embryonic lobster, Homarus americanus. J Neurochem. 2008 May;105(3):690-702. doi: 10.1111/j.1471-4159.2007.05154.x. Epub 2007 Dec 6. PubMed PMID: 18088365.
Wang J, Ma M, Chen R, Li L. Enhanced neuropeptide profiling via capillary electrophoresis off-line coupled with MALDI FTMS. Anal Chem. 2008 Aug 15;80(16):6168-77. doi: 10.1021/ac800382t. Epub 2008 Jul 22. PubMed PMID: 18642879; PubMed Central PMCID: PMC2546495.
Dowell JA, Frost DC, Zhang J, Li L. Comparison of two-dimensional fractionation techniques for shotgun proteomics. Anal Chem. 2008 Sep 1;80(17):6715-23. doi: 10.1021/ac8007994. Epub 2008 Aug 5. PubMed PMID: 18680313; PubMed Central PMCID: PMC2548321.
Behrens HL, Chen R, Li L. Combining microdialysis, NanoLC-MS, and MALDI-TOF/TOF to detect neuropeptides secreted in the crab, Cancer borealis. Anal Chem. 2008 Sep 15;80(18):6949-58. doi: 10.1021/ac800798h. Epub 2008 Aug 14. PubMed PMID: 18700782; PubMed Central PMCID: PMC2602843.
Christie AE, Cashman CR, Stevens JS, Smith CM, Beale KM, Stemmler EA, Greenwood SJ, Towle DW, Dickinson PS. Identification and cardiotropic actions of brain/gut-derived tachykinin-related peptides (TRPs) from the American lobster Homarus americanus. Peptides. 2008 Nov;29(11):1909-18. doi: 10.1016/j.peptides.2008.07.010. Epub 2008 Jul 24. PubMed PMID: 18706463; NIHMSID:NIHMS77597.
Ma M, Chen R, Ge Y, He H, Marshall AG, Li L. Combining bottom-up and top-down mass spectrometric strategies for de novo sequencing of the crustacean hyperglycemic hormone from Cancer borealis. Anal Chem. 2009 Jan 1;81(1):240-7. doi: 10.1021/ac801910g. PubMed PMID: 19046072; PubMed Central PMCID: PMC2652649.
Cape SS, Dowell JA, Li L. Mass spectrometric characterization of neuropeptides. Methods Mol Biol. 2009;492:381-93. doi: 10.1007/978-1-59745-493-3_23. PubMed PMID: 19241046.
Wei X, Li L. Mass spectrometry-based proteomics and peptidomics for biomarker discovery in neurodegenerative diseases. Int J Clin Exp Pathol. 2009;2(2):132-48. Epub 2008 Jun 20. PubMed PMID: 19079648; PubMed Central PMCID: PMC2583631.
Herbst A, McIlwain S, Schmidt JJ, Aiken JM, Page CD, Li L. Prion disease diagnosis by proteomic profiling. J Proteome Res. 2009 Feb;8(2):1030-6. doi: 10.1021/pr800832s. PubMed PMID: 19133784; PubMed Central PMCID: PMC2652651.
Cho YK, Chen I, Wei X, Li L, Shusta EV. A yeast display immunoprecipitation method for efficient isolation and characterization of antigens. J Immunol Methods. 2009 Feb 28;341(1-2):117-26. doi: 10.1016/j.jim.2008.11.005. Epub 2008 Nov 28. PubMed PMID: 19041873; PubMed Central PMCID: PMC2637942.
Yew JY, Wang Y, Barteneva N, Dikler S, Kutz-Naber KK, Li L, Kravitz EA. Analysis of neuropeptide expression and localization in adult drosophila melanogaster central nervous system by affinity cell-capture mass spectrometry. J Proteome Res. 2009 Mar;8(3):1271-84. doi: 10.1021/pr800601x. PubMed PMID: 19199706; PubMed Central PMCID: PMC2693453.
Wei X, Li L. Comparative glycoproteomics: approaches and applications. Brief Funct Genomic Proteomic. 2009 Mar;8(2):104-13. doi: 10.1093/bfgp/eln053. Epub 2008 Dec 17. Review. PubMed PMID: 19091783; PubMed Central PMCID: PMC2673949.
Chen R, Ma M, Hui L, Zhang J, Li L. Measurement of neuropeptides in crustacean hemolymph via MALDI mass spectrometry. J Am Soc Mass Spectrom. 2009 Apr;20(4):708-18. doi: 10.1016/j.jasms.2008.12.007. Epub 2008 Dec 24. PubMed PMID: 19185513; PubMed Central PMCID: PMC2756545.
Ma M, Bors EK, Dickinson ES, Kwiatkowski MA, Sousa GL, Henry RP, Smith CM, Towle DW, Christie AE, Li L. Characterization of the Carcinus maenas neuropeptidome by mass spectrometry and functional genomics. Gen Comp Endocrinol. 2009 May;161(3):320-34. doi: 10.1016/j.ygcen.2009.01.015. Epub 2009 Jan 31. PubMed PMID: 19523386; PubMed Central PMCID: PMC2888039.
Ma M, Wang J, Chen R, Li L. Expanding the Crustacean neuropeptidome using a multifaceted mass spectrometric approach. J Proteome Res. 2009 May;8(5):2426-37. doi: 10.1021/pr801047v. PubMed PMID: 19222238; PubMed Central PMCID: PMC2692460.
Chen R, Hui L, Sturm RM, Li L. Three dimensional mapping of neuropeptides and lipids in crustacean brain by mass spectral imaging. J Am Soc Mass Spectrom. 2009 Jun;20(6):1068-77. doi: 10.1016/j.jasms.2009.01.017. Epub 2009 Jan 31. PubMed PMID: 19264504; PubMed Central PMCID: PMC2756544.
Dowell JA, Johnson JA, Li L. Identification of astrocyte secreted proteins with a combination of shotgun proteomics and bioinformatics. J Proteome Res. 2009 Aug;8(8):4135-43. doi: 10.1021/pr900248y. PubMed PMID: 19469553; PubMed Central PMCID: PMC2866504.
Ma M, Szabo TM, Jia C, Marder E, Li L. Mass spectrometric characterization and physiological actions of novel crustacean C-type allatostatins. Peptides. 2009 Sep;30(9):1660-8. doi: 10.1016/j.peptides.2009.05.023. Epub 2009 Jun 6. PubMed PMID: 19505516; PubMed Central PMCID: PMC2721915.
Wang J, Jiang X, Sturm RM, Li L. Combining tissue extraction and off-line capillary electrophoresis matrix-assisted laser desorption/ionization Fourier transform mass spectrometry for neuropeptide analysis in individual neuronal organs using 2,5-dihydroxybenzoic acid as a multi-functional agent. J Chromatogr A. 2009 Nov 20;1216(47):8283-8. doi: 10.1016/j.chroma.2009.04.085. Epub 2009 May 4. PubMed PMID: 19473662; PubMed Central PMCID: PMC2783529.
Ma M, Sturm RM, Kutz-Naber KK, Fu Q, Li L. Immunoaffinity-based mass spectrometric characterization of the FMRFamide-related peptide family in the pericardial organ of Cancer borealis. Biochem Biophys Res Commun. 2009 Dec 11;390(2):325-30. doi: 10.1016/j.bbrc.2009.09.122. Epub 2009 Oct 1. PubMed PMID: 19800311; PubMed Central PMCID: PMC2767467.
Ma M, Gard AL, Xiang F, Wang J, Davoodian N, Lenz PH, Malecha SR, Christie AE, Li L. Combining in silico transcriptome mining and biological mass spectrometry for neuropeptide discovery in the Pacific white shrimp Litopenaeus vannamei. Peptides. 2010 Jan;31(1):27-43. doi: 10.1016/j.peptides.2009.10.007. Epub 2009 Oct 21. PubMed PMID: 19852991; PubMed Central PMCID: PMC2815327.
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