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Choubey D, Gopinathan KP. Characterization of beta-lactamase from Mycobacterium butyricum ATCC 19979. Biochem Int. 1986 Feb;12(2):207-14. PubMed PMID: 3485977.
Kumar R, Choubey D, Lengyel P, Sen GC. Studies on the role of the 2'-5'-oligoadenylate synthetase-RNase L pathway in beta interferon-mediated inhibition of encephalomyocarditis virus replication. J Virol. 1988 Sep;62(9):3175-81. doi: 10.1128/JVI.62.9.3175-3181.1988. PubMed PMID: 2841470; PubMed Central PMCID: PMC253435.
Kingsmore SF, Snoddy J, Choubey D, Lengyel P, Seldin MF. Physical mapping of a family of interferon-activated genes, serum amyloid P-component, and alpha-spectrin on mouse chromosome 1. Immunogenetics. 1989;30(3):169-74. doi: 10.1007/bf02421202. PubMed PMID: 2476388.
Opdenakker G, Snoddy J, Choubey D, Toniato E, Pravtcheva DD, Seldin MF, Ruddle FH, Lengyel P. Interferons as gene activators: a cluster of six interferon-activatable genes is linked to the erythroid alpha-spectrin locus on murine chromosome 1. Virology. 1989 Aug;171(2):568-78. doi: 10.1016/0042-6822(89)90626-0. PubMed PMID: 2474894.
Choubey D, Snoddy J, Chaturvedi V, Toniato E, Opdenakker G, Thakur A, Samanta H, Engel DA, Lengyel P. Interferons as gene activators. Indications for repeated gene duplication during the evolution of a cluster of interferon-activatable genes on murine chromosome 1. J Biol Chem. 1989 Oct 15;264(29):17182-9. PubMed PMID: 2477366.
Choubey D, Lengyel P. Interferon action: nucleolar and nucleoplasmic localization of the interferon-inducible 72-kD protein that is encoded by the Ifi 204 gene from the gene 200 cluster. J Cell Biol. 1992 Mar;116(6):1333-41. doi: 10.1083/jcb.116.6.1333. PubMed PMID: 1541632; PubMed Central PMCID: PMC2289372.
Choubey D, Lengyel P. Interferon action: cytoplasmic and nuclear localization of the interferon-inducible 52-kD protein that is encoded by the Ifi 200 gene from the gene 200 cluster. J Interferon Res. 1993 Feb;13(1):43-52. doi: 10.1089/jir.1993.13.43. PubMed PMID: 8454910.
Choubey D, Lengyel P. Binding of an interferon-inducible protein (p202) to the retinoblastoma protein. J Biol Chem. 1995 Mar 17;270(11):6134-40. doi: 10.1074/jbc.270.11.6134. PubMed PMID: 7890747.
Choubey D, Gutterman JU. The interferon-inducible growth-inhibitory p202 protein: DNA binding properties and identification of a DNA binding domain. Biochem Biophys Res Commun. 1996 Apr 16;221(2):396-401. doi: 10.1006/bbrc.1996.0607. PubMed PMID: 8619867.
Choubey D, Li SJ, Datta B, Gutterman JU, Lengyel P. Inhibition of E2F-mediated transcription by p202. EMBO J. 1996 Oct 15;15(20):5668-78. PubMed PMID: 8896460; PubMed Central PMCID: PMC452311.
Choubey D, Gutterman JU. Inhibition of E2F-4/DP-1-stimulated transcription by p202. Oncogene. 1997 Jul 17;15(3):291-301. doi: 10.1038/sj.onc.1201184. PubMed PMID: 9233764.
Koul D, Lapushin R, Xu HJ, Mills GB, Gutterman JU, Choubey D. p202 prevents apoptosis in murine AKR-2B fibroblasts. Biochem Biophys Res Commun. 1998 Jun 18;247(2):379-82. doi: 10.1006/bbrc.1998.8804. PubMed PMID: 9642135.
Koul D, Obeyesekere NU, Gutterman JU, Mills GB, Choubey D. p202 self-associates through a sequence conserved among the members of the 200-family proteins. FEBS Lett. 1998 Oct 30;438(1-2):21-4. doi: 10.1016/s0014-5793(98)01263-0. PubMed PMID: 9821952.
Yan DH, Wen Y, Spohn B, Choubey D, Gutterman JU, Hung MC. Reduced growth rate and transformation phenotype of the prostate cancer cells by an interferon-inducible protein, p202. Oncogene. 1999 Jan 21;18(3):807-11. doi: 10.1038/sj.onc.1202369. PubMed PMID: 9989832.
Gutterman JU, Choubey D. Retardation of cell proliferation after expression of p202 accompanies an increase in p21(WAF1/CIP1). Cell Growth Differ. 1999 Feb;10(2):93-100. PubMed PMID: 10074903.
Chaturvedi V, Qin JZ, Denning MF, Choubey D, Diaz MO, Nickoloff BJ. Apoptosis in proliferating, senescent, and immortalized keratinocytes. J Biol Chem. 1999 Aug 13;274(33):23358-67. doi: 10.1074/jbc.274.33.23358. PubMed PMID: 10438513.
Qin JZ, Chaturvedi V, Denning MF, Choubey D, Diaz MO, Nickoloff BJ. Role of NF-kappaB in the apoptotic-resistant phenotype of keratinocytes. J Biol Chem. 1999 Dec 31;274(53):37957-64. doi: 10.1074/jbc.274.53.37957. PubMed PMID: 10608863.
Choubey D, Walter S, Geng Y, Xin H. Cytoplasmic localization of the interferon-inducible protein that is encoded by the AIM2 (absent in melanoma) gene from the 200-gene family. FEBS Lett. 2000 May 26;474(1):38-42. doi: 10.1016/s0014-5793(00)01571-4. PubMed PMID: 10828447.
Choubey D. P202: an interferon-inducible negative regulator of cell growth. J Biol Regul Homeost Agents. 2000 Jul-Sep;14(3):187-92. Review. PubMed PMID: 11037051.
Geng Y, D'Souza S, Xin H, Walter S, Choubey D. p202 levels are negatively regulated by serum growth factors. Cell Growth Differ. 2000 Sep;11(9):475-83. PubMed PMID: 11007452.
Geng Y, Choubey D. Differential induction of the 200-family proteins in Daudi Burkitt's lymphoma cells by interferon-alpha. J Biol Regul Homeost Agents. 2000 Oct-Dec;14(4):263-8. Review. PubMed PMID: 11215814.
D'Souza S, Xin H, Walter S, Choubey D. The gene encoding p202, an interferon-inducible negative regulator of the p53 tumor suppressor, is a target of p53-mediated transcriptional repression. J Biol Chem. 2001 Jan 5;276(1):298-305. doi: 10.1074/jbc.M007155200. PubMed PMID: 11013253.
Chaturvedi V, Qin JZ, Denning MF, Choubey D, Diaz MO, Nickoloff BJ. Abnormal NF-kappaB signaling pathway with enhanced susceptibility to apoptosis in immortalized keratinocytes. J Dermatol Sci. 2001 May;26(1):67-78. doi: 10.1016/s0923-1811(00)00157-2. PubMed PMID: 11323223.
Rozzo SJ, Allard JD, Choubey D, Vyse TJ, Izui S, Peltz G, Kotzin BL. Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus. Immunity. 2001 Sep;15(3):435-43. doi: 10.1016/s1074-7613(01)00196-0. PubMed PMID: 11567633.
Xin H, D'Souza S, Fang L, Lengyel P, Choubey D. p202, an interferon-inducible negative regulator of cell growth, is a target of the adenovirus E1A protein. Oncogene. 2001 Oct 18;20(47):6828-39. doi: 10.1038/sj.onc.1204844. PubMed PMID: 11687962.
Choubey D, Kotzin BL. Interferon-inducible p202 in the susceptibility to systemic lupus. Front Biosci. 2002 May 1;7:e252-62. doi: 10.2741/A921. Review. PubMed PMID: 11991834.
Qin JZ, Chaturvedi V, Denning MF, Bacon P, Panella J, Choubey D, Nickoloff BJ. Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes. Oncogene. 2002 May 2;21(19):2991-3002. doi: 10.1038/sj.onc.1205404. PubMed PMID: 12082529.
Chaturvedi V, Cesnjaj M, Bacon P, Panella J, Choubey D, Diaz MO, Nickoloff BJ. Role of INK4a/Arf locus-encoded senescent checkpoints activated in normal and psoriatic keratinocytes. Am J Pathol. 2003 Jan;162(1):161-70. doi: 10.1016/S0002-9440(10)63807-2. PubMed PMID: 12507899; PubMed Central PMCID: PMC1851109.
Xin H, Geng Y, Pramanik R, Choubey D. Induction of p202, a modulator of apoptosis, during oncogenic transformation of NIH 3T3 cells by activated H-Ras (Q61L) contributes to cell survival. J Cell Biochem. 2003 Jan 1;88(1):191-204. doi: 10.1002/jcb.10372. PubMed PMID: 12461788.
Pramanik R, Qi X, Borowicz S, Choubey D, Schultz RM, Han J, Chen G. p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity. J Biol Chem. 2003 Feb 14;278(7):4831-9. doi: 10.1074/jbc.M207732200. Epub 2002 Dec 9. PubMed PMID: 12475989.
Santiago-Raber ML, Baccala R, Haraldsson KM, Choubey D, Stewart TA, Kono DH, Theofilopoulos AN. Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice. J Exp Med. 2003 Mar 17;197(6):777-88. doi: 10.1084/jem.20021996. PubMed PMID: 12642605; PubMed Central PMCID: PMC2193854.
Amrani Y, Tliba O, Choubey D, Huang CD, Krymskaya VP, Eszterhas A, Lazaar AL, Panettieri RA Jr. IFN-gamma inhibits human airway smooth muscle cell proliferation by modulating the E2F-1/Rb pathway. Am J Physiol Lung Cell Mol Physiol. 2003 Jun;284(6):L1063-71. doi: 10.1152/ajplung.00363.2002. Epub 2003 Feb 14. PubMed PMID: 12588705.
Xin H, Pramanik R, Choubey D. Retinoblastoma (Rb) protein upregulates expression of the Ifi202 gene encoding an interferon-inducible negative regulator of cell growth. Oncogene. 2003 Jul 31;22(31):4775-85. doi: 10.1038/sj.onc.1206780. PubMed PMID: 12894219.
Xin H, Curry J, Johnstone RW, Nickoloff BJ, Choubey D. Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence. Oncogene. 2003 Jul 31;22(31):4831-40. doi: 10.1038/sj.onc.1206754. PubMed PMID: 12894224.
Choubey D, Pramanik R, Xin H. Subcellular localization and mechanisms of nucleocytoplasmic distribution of p202, an interferon-inducible candidate for lupus susceptibility. FEBS Lett. 2003 Oct 23;553(3):245-9. doi: 10.1016/s0014-5793(03)01006-8. PubMed PMID: 14572632.
Chaturvedi V, Qin JZ, Stennett L, Choubey D, Nickoloff BJ. Resistance to UV-induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53. J Cell Physiol. 2004 Jan;198(1):100-9. doi: 10.1002/jcp.10392. PubMed PMID: 14584049.
Pramanik R, Jørgensen TN, Xin H, Kotzin BL, Choubey D. Interleukin-6 induces expression of Ifi202, an interferon-inducible candidate gene for lupus susceptibility. J Biol Chem. 2004 Apr 16;279(16):16121-7. doi: 10.1074/jbc.M313140200. Epub 2004 Feb 5. PubMed PMID: 14764608.
Xin H, Pereira-Smith OM, Choubey D. Role of IFI 16 in cellular senescence of human fibroblasts. Oncogene. 2004 Aug 19;23(37):6209-17. doi: 10.1038/sj.onc.1207836. PubMed PMID: 15208661.
Albrecht M, Choubey D, Lengauer T. The HIN domain of IFI-200 proteins consists of two OB folds. Biochem Biophys Res Commun. 2005 Feb 18;327(3):679-87. doi: 10.1016/j.bbrc.2004.12.056. PubMed PMID: 15649401.
Alimirah F, Chen J, Xin H, Choubey D. Androgen receptor auto-regulates its expression by a negative feedback loop through upregulation of IFI16 protein. FEBS Lett. 2006 Mar 6;580(6):1659-64. doi: 10.1016/j.febslet.2006.02.015. Epub 2006 Feb 17. PubMed PMID: 16494870.
Alimirah F, Chen J, Basrawala Z, Xin H, Choubey D. DU-145 and PC-3 human prostate cancer cell lines express androgen receptor: implications for the androgen receptor functions and regulation. FEBS Lett. 2006 Apr 17;580(9):2294-300. doi: 10.1016/j.febslet.2006.03.041. Epub 2006 Mar 24. PubMed PMID: 16580667.
Basrawala Z, Alimirah F, Xin H, Mohideen N, Campbell SC, Flanigan RC, Choubey D. Androgen receptor levels are increased by interferons in human prostate stromal and epithelial cells. Oncogene. 2006 May 4;25(19):2812-7. doi: 10.1038/sj.onc.1209304. PubMed PMID: 16331249.
Xin H, D'Souza S, Jørgensen TN, Vaughan AT, Lengyel P, Kotzin BL, Choubey D. Increased expression of Ifi202, an IFN-activatable gene, in B6.Nba2 lupus susceptible mice inhibits p53-mediated apoptosis. J Immunol. 2006 May 15;176(10):5863-70. doi: 10.4049/jimmunol.176.10.5863. PubMed PMID: 16670293.
Alimirah F, Chen J, Davis FJ, Choubey D. IFI16 in human prostate cancer. Mol Cancer Res. 2007 Mar;5(3):251-9. doi: 10.1158/1541-7786.MCR-06-0269. Epub 2007 Mar 5. PubMed PMID: 17339605.
Alimirah F, Panchanathan R, Davis FJ, Chen J, Choubey D. Restoration of p53 expression in human cancer cell lines upregulates the expression of Notch1: implications for cancer cell fate determination after genotoxic stress. Neoplasia. 2007 May;9(5):427-34. doi: 10.1593/neo.07211. PubMed PMID: 17534448; PubMed Central PMCID: PMC1877974.
Alimirah F, Panchanathan R, Chen J, Zhang X, Ho SM, Choubey D. Expression of androgen receptor is negatively regulated by p53. Neoplasia. 2007 Dec;9(12):1152-9. doi: 10.1593/neo.07769. PubMed PMID: 18084622; PubMed Central PMCID: PMC2134911.
Kim MK, Mason JM, Li CM, Berkofsky-Fessler W, Jiang L, Choubey D, Grundy PE, Tycko B, Licht JD. A pathologic link between Wilms tumor suppressor gene, WT1, and IFI16. Neoplasia. 2008 Jan;10(1):69-78. doi: 10.1593/neo.07869. PubMed PMID: 18231640; PubMed Central PMCID: PMC2213901.
Choubey D, Deka R, Ho SM. Interferon-inducible IFI16 protein in human cancers and autoimmune diseases. Front Biosci. 2008 Jan 1;13:598-608. doi: 10.2741/2705. Review. PubMed PMID: 17981573.
Choubey D. Comment on: The candidate lupus susceptibility gene Ifi202a is largely dispensable for B-cell function. Rheumatology (Oxford). 2008 Apr;47(4):558-9; author reply 559. doi: 10.1093/rheumatology/ken018. Epub 2008 Feb 13. PubMed PMID: 18272531.
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