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Scofield MD, Brüschweiler-Li L, Mou Z, Gardner PD. Transcription factor assembly on the nicotinic receptor beta4 subunit gene promoter. Neuroreport. 2008 Apr 16;19(6):687-90. doi: 10.1097/WNR.0b013e3282fbcef7. PubMed PMID: 18382288.
Bruschweiler-Li L, Fuentes Medel YF, Scofield MD, Trang EB, Binke SA, Gardner PD. Temporally- and spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor beta4 subunit gene promoter. Neuroscience. 2010 Mar 31;166(3):864-77. doi: 10.1016/j.neuroscience.2010.01.026. Epub 2010 Jan 20. PubMed PMID: 20096338; PubMed Central PMCID: PMC2837126.
Improgo MR, Scofield MD, Tapper AR, Gardner PD. From smoking to lung cancer: the CHRNA5/A3/B4 connection. Oncogene. 2010 Sep 2;29(35):4874-84. doi: 10.1038/onc.2010.256. Epub 2010 Jun 28. Review. PubMed PMID: 20581870; PubMed Central PMCID: PMC3934347.
Improgo MR, Scofield MD, Tapper AR, Gardner PD. The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer. Prog Neurobiol. 2010 Oct;92(2):212-26. doi: 10.1016/j.pneurobio.2010.05.003. Epub 2010 Jun 4. Review. PubMed PMID: 20685379; PubMed Central PMCID: PMC2939268.
Scofield MD, Tapper AR, Gardner PD. A transcriptional regulatory element critical for CHRNB4 promoter activity in vivo. Neuroscience. 2010 Nov 10;170(4):1056-64. doi: 10.1016/j.neuroscience.2010.08.007. Epub 2010 Aug 6. PubMed PMID: 20696214; PubMed Central PMCID: PMC2949541.
Scofield MD, Korutla L, Jackson TG, Kalivas PW, Mackler SA. Nucleus Accumbens 1, a Pox virus and Zinc finger/Bric-a-brac Tramtrack Broad protein binds to TAR DNA-binding protein 43 and has a potential role in Amyotrophic Lateral Sclerosis. Neuroscience. 2012 Dec 27;227:44-54. doi: 10.1016/j.neuroscience.2012.09.043. Epub 2012 Sep 25. PubMed PMID: 23022214; PubMed Central PMCID: PMC3505276.
Scofield MD, Kalivas PW. Forgiving the sins of the fathers. Nat Neurosci. 2013 Jan;16(1):4-5. doi: 10.1038/nn.3288. PubMed PMID: 23257926; PubMed Central PMCID: PMC4913885.
Kupchik YM, Scofield MD, Rice KC, Cheng K, Roques BP, Kalivas PW. Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum. J Neurosci. 2014 Jan 15;34(3):1057-66. doi: 10.1523/JNEUROSCI.4336-13.2014. PubMed PMID: 24431463; PubMed Central PMCID: PMC3891949.
Shen HW, Scofield MD, Boger H, Hensley M, Kalivas PW. Synaptic glutamate spillover due to impaired glutamate uptake mediates heroin relapse. J Neurosci. 2014 Apr 16;34(16):5649-57. doi: 10.1523/JNEUROSCI.4564-13.2014. PubMed PMID: 24741055; PubMed Central PMCID: PMC3988415.
Stankeviciute NM, Scofield MD, Kalivas PW, Gipson CD. Rapid, transient potentiation of dendritic spines in context-induced relapse to cocaine seeking. Addict Biol. 2014 Nov;19(6):972-4. doi: 10.1111/adb.12064. Epub 2013 May 6. PubMed PMID: 23648005; PubMed Central PMCID: PMC3742620.
Scofield MD, Kalivas PW. Astrocytic dysfunction and addiction: consequences of impaired glutamate homeostasis. Neuroscientist. 2014 Dec;20(6):610-22. doi: 10.1177/1073858413520347. Epub 2014 Feb 3. Review. PubMed PMID: 24496610; PubMed Central PMCID: PMC4913887.
Hogan EM, Casserly AP, Scofield MD, Mou Z, Zhao-Shea R, Johnson CW, Tapper AR, Gardner PD. miRNAome analysis of the mammalian neuronal nicotinic acetylcholine receptor gene family. RNA. 2014 Dec;20(12):1890-9. doi: 10.1261/rna.034066.112. Epub 2014 Oct 24. PubMed PMID: 25344397; PubMed Central PMCID: PMC4238110.
Smith AC, Kupchik YM, Scofield MD, Gipson CD, Wiggins A, Thomas CA, Kalivas PW. Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases. Nat Neurosci. 2014 Dec;17(12):1655-7. doi: 10.1038/nn.3846. Epub 2014 Oct 19. PubMed PMID: 25326689; PubMed Central PMCID: PMC4241163.
Reissner KJ, Gipson CD, Tran PK, Knackstedt LA, Scofield MD, Kalivas PW. Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement. Addict Biol. 2015 Mar;20(2):316-23. doi: 10.1111/adb.12127. Epub 2014 Feb 25. PubMed PMID: 24612076; PubMed Central PMCID: PMC4437505.
Farrand AQ, Gregory RA, Scofield MD, Helke KL, Boger HA. Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice. Neurobiol Aging. 2015 Mar;36(3):1569-76. doi: 10.1016/j.neurobiolaging.2014.11.017. Epub 2014 Dec 12. PubMed PMID: 25577412; PubMed Central PMCID: PMC4346478.
Scofield MD, Trantham-Davidson H, Schwendt M, Leong KC, Peters J, See RE, Reichel CM. Failure to Recognize Novelty after Extended Methamphetamine Self-Administration Results from Loss of Long-Term Depression in the Perirhinal Cortex. Neuropsychopharmacology. 2015 Oct;40(11):2526-35. doi: 10.1038/npp.2015.99. Epub 2015 Apr 13. PubMed PMID: 25865928; PubMed Central PMCID: PMC4569960.
Scofield MD, Boger HA, Smith RJ, Li H, Haydon PG, Kalivas PW. Gq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine Seeking. Biol Psychiatry. 2015 Oct 1;78(7):441-51. doi: 10.1016/j.biopsych.2015.02.016. Epub 2015 Feb 24. PubMed PMID: 25861696; PubMed Central PMCID: PMC4547911.
Smith AC, Scofield MD, Kalivas PW. The tetrapartite synapse: Extracellular matrix remodeling contributes to corticoaccumbens plasticity underlying drug addiction. Brain Res. 2015 Dec 2;1628(Pt A):29-39. doi: 10.1016/j.brainres.2015.03.027. Epub 2015 Mar 30. Review. PubMed PMID: 25838241; PubMed Central PMCID: PMC4589426.
Peters J, Scofield MD, Ghee SM, Heinsbroek JA, Reichel CM. Perirhinal Cortex mGlu5 Receptor Activation Reduces Relapse to Methamphetamine Seeking by Restoring Novelty Salience. Neuropsychopharmacology. 2016 May;41(6):1477-85. doi: 10.1038/npp.2015.283. Epub 2015 Sep 14. PubMed PMID: 26365953; PubMed Central PMCID: PMC4832007.
Scofield MD, Heinsbroek JA, Gipson CD, Kupchik YM, Spencer S, Smith AC, Roberts-Wolfe D, Kalivas PW. The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis. Pharmacol Rev. 2016 Jul;68(3):816-71. doi: 10.1124/pr.116.012484. Review. PubMed PMID: 27363441; PubMed Central PMCID: PMC4931870.
Scofield MD, Li H, Siemsen BM, Healey KL, Tran PK, Woronoff N, Boger HA, Kalivas PW, Reissner KJ. Cocaine Self-Administration and Extinction Leads to Reduced Glial Fibrillary Acidic Protein Expression and Morphometric Features of Astrocytes in the Nucleus Accumbens Core. Biol Psychiatry. 2016 Aug 1;80(3):207-15. doi: 10.1016/j.biopsych.2015.12.022. Epub 2015 Dec 31. PubMed PMID: 26946381; PubMed Central PMCID: PMC4930433.
Spencer S, Scofield M, Kalivas PW. The good and bad news about glutamate in drug addiction. J Psychopharmacol. 2016 Nov;30(11):1095-1098. doi: 10.1177/0269881116655248. Epub 2016 Jun 28. Review. PubMed PMID: 27353027; PubMed Central PMCID: PMC5234332.
Smith ACW, Scofield MD, Heinsbroek JA, Gipson CD, Neuhofer D, Roberts-Wolfe DJ, Spencer S, Garcia-Keller C, Stankeviciute NM, Smith RJ, Allen NP, Lorang MR, Griffin WC 3rd, Boger HA, Kalivas PW. Accumbens nNOS Interneurons Regulate Cocaine Relapse. J Neurosci. 2017 Jan 25;37(4):742-756. doi: 10.1523/JNEUROSCI.2673-16.2016. PubMed PMID: 28123012; PubMed Central PMCID: PMC5296777.
Scofield MD. Similitude in Methamphetamine-Induced Neuroadaptations Across Susceptibility and Chronic Drug Exposure Paradigms. Biol Psychiatry. 2017 Jun 1;81(11):e83-e84. doi: 10.1016/j.biopsych.2017.02.1178. PubMed PMID: 28502394; PubMed Central PMCID: PMC6459405.
Bobadilla AC, Garcia-Keller C, Heinsbroek JA, Scofield MD, Chareunsouk V, Monforton C, Kalivas PW. Accumbens Mechanisms for Cued Sucrose Seeking. Neuropsychopharmacology. 2017 Nov;42(12):2377-2386. doi: 10.1038/npp.2017.153. Epub 2017 Jul 20. PubMed PMID: 28726801; PubMed Central PMCID: PMC5645741.
Spencer S, Neuhofer D, Chioma VC, Garcia-Keller C, Schwartz DJ, Allen N, Scofield MD, Ortiz-Ithier T, Kalivas PW. A Model of Δ9-Tetrahydrocannabinol Self-administration and Reinstatement That Alters Synaptic Plasticity in Nucleus Accumbens. Biol Psychiatry. 2018 Oct 15;84(8):601-610. doi: 10.1016/j.biopsych.2018.04.016. Epub 2018 May 3. PubMed PMID: 29861097; PubMed Central PMCID: PMC6162175.
Scofield MD. Exploring the Role of Astroglial Glutamate Release and Association With Synapses in Neuronal Function and Behavior. Biol Psychiatry. 2018 Dec 1;84(11):778-786. doi: 10.1016/j.biopsych.2017.10.029. Epub 2017 Nov 11. Review. PubMed PMID: 29258653; PubMed Central PMCID: PMC5948108.
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