My Bibliography

select

Philips RL, Wang Y, Cheon H, Kanno Y, Gadina M, Sartorelli V, Horvath CM, Darnell JE Jr, Stark GR, O'Shea JJ. The JAK-STAT pathway at 30: Much learned, much more to do. Cell. 2022 Oct 13;185(21):3857-3876. doi: 10.1016/j.cell.2022.09.023. Review. PubMed PMID: 36240739; PubMed Central PMCID: PMC9815833.

select

Cheon H, Wang Y, Wightman SM, Jackson MW, Stark GR. How cancer cells make and respond to interferon-I. Trends Cancer. 2023 Jan;9(1):83-92. doi: 10.1016/j.trecan.2022.09.003. Epub 2022 Oct 8. Review. PubMed PMID: 36216730; PubMed Central PMCID: PMC9797472.

select

Cheon H, Holvey-Bates EG, McGrail DJ, Stark GR. PD-L1 sustains chronic, cancer cell-intrinsic responses to type I interferon, enhancing resistance to DNA damage. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47). doi: 10.1073/pnas.2112258118. PubMed PMID: 34799452; PubMed Central PMCID: PMC8617513.

select

Kondratova A, Cheon H, Dong B, Holvey-Bates EG, Hasipek M, Taran I, Gaughan C, Jha BK, Silverman RH, Stark GR. Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death. EMBO J. 2020 Oct 15;39(20):e106593. doi: 10.15252/embj.2020106593. PubMed PMID: 33058249; PubMed Central PMCID: PMC7560197.

select

Kondratova AA, Cheon H, Dong B, Holvey-Bates EG, Hasipek M, Taran I, Gaughan C, Jha BK, Silverman RH, Stark GR. Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death. EMBO J. 2020 Jun 2;39(11):e101573. doi: 10.15252/embj.2019101573. Epub 2020 Apr 23. PubMed PMID: 32323871; PubMed Central PMCID: PMC7265237.

select

Doherty MR, Parvani JG, Tamagno I, Junk DJ, Bryson BL, Cheon HJ, Stark GR, Jackson MW. The opposing effects of interferon-beta and oncostatin-M as regulators of cancer stem cell plasticity in triple-negative breast cancer. Breast Cancer Res. 2019 Apr 29;21(1):54. doi: 10.1186/s13058-019-1136-x. PubMed PMID: 31036052; PubMed Central PMCID: PMC6489282.

select

Stark GR, Cheon H, Wang Y. Responses to Cytokines and Interferons that Depend upon JAKs and STATs. Cold Spring Harb Perspect Biol. 2018 Jan 2;10(1). doi: 10.1101/cshperspect.a028555. Review. PubMed PMID: 28620095; PubMed Central PMCID: PMC5749152.

select

Doherty MR, Cheon H, Junk DJ, Vinayak S, Varadan V, Telli ML, Ford JM, Stark GR, Jackson MW. Interferon-beta represses cancer stem cell properties in triple-negative breast cancer. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13792-13797. doi: 10.1073/pnas.1713728114. Epub 2017 Dec 11. PubMed PMID: 29229854; PubMed Central PMCID: PMC5748193.

select

Majoros A, Platanitis E, Szappanos D, Cheon H, Vogl C, Shukla P, Stark GR, Sexl V, Schreiber R, Schindler C, Müller M, Decker T. Response to interferons and antibacterial innate immunity in the absence of tyrosine-phosphorylated STAT1. EMBO Rep. 2016 Mar;17(3):367-82. doi: 10.15252/embr.201540726. Epub 2016 Feb 12. PubMed PMID: 26882544; PubMed Central PMCID: PMC4772975.

select

Sung PS, Cheon H, Cho CH, Hong SH, Park DY, Seo HI, Park SH, Yoon SK, Stark GR, Shin EC. Roles of unphosphorylated ISGF3 in HCV infection and interferon responsiveness. Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10443-8. doi: 10.1073/pnas.1513341112. Epub 2015 Jul 27. PubMed PMID: 26216956; PubMed Central PMCID: PMC4547285.

select

Wienerroither S, Shukla P, Farlik M, Majoros A, Stych B, Vogl C, Cheon H, Stark GR, Strobl B, Müller M, Decker T. Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex. Cell Rep. 2015 Jul 14;12(2):300-12. doi: 10.1016/j.celrep.2015.06.021. Epub 2015 Jul 2. PubMed PMID: 26146080; PubMed Central PMCID: PMC4521078.

select

Kolosenko I, Fryknäs M, Forsberg S, Johnsson P, Cheon H, Holvey-Bates EG, Edsbäcker E, Pellegrini P, Rassoolzadeh H, Brnjic S, Larsson R, Stark GR, Grandér D, Linder S, Tamm KP, De Milito A. Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs. Int J Cancer. 2015 Feb 15;136(4):E51-61. doi: 10.1002/ijc.29161. Epub 2014 Sep 4. PubMed PMID: 25156627.

select

Cheon H, Borden EC, Stark GR. Interferons and their stimulated genes in the tumor microenvironment. Semin Oncol. 2014 Apr;41(2):156-73. doi: 10.1053/j.seminoncol.2014.02.002. Epub 2014 Feb 14. Review. PubMed PMID: 24787290; PubMed Central PMCID: PMC4118773.

select

Wang Y, van Boxel-Dezaire AH, Cheon H, Yang J, Stark GR. STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16975-80. doi: 10.1073/pnas.1315862110. Epub 2013 Sep 30. PubMed PMID: 24082147; PubMed Central PMCID: PMC3801081.

select

Cheon H, Holvey-Bates EG, Schoggins JW, Forster S, Hertzog P, Imanaka N, Rice CM, Jackson MW, Junk DJ, Stark GR. IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage. EMBO J. 2013 Oct 16;32(20):2751-63. doi: 10.1038/emboj.2013.203. Epub 2013 Sep 24. PubMed PMID: 24065129; PubMed Central PMCID: PMC3801437.

select

Cheon H, Yang J, Stark GR. The functions of signal transducers and activators of transcriptions 1 and 3 as cytokine-inducible proteins. J Interferon Cytokine Res. 2011 Jan;31(1):33-40. doi: 10.1089/jir.2010.0100. Epub 2010 Dec 19. Review. PubMed PMID: 21166594; PubMed Central PMCID: PMC3021352.

select

Cheon H, Stark GR. Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9373-8. doi: 10.1073/pnas.0903487106. Epub 2009 May 28. PubMed PMID: 19478064; PubMed Central PMCID: PMC2688000.

select

Cheon H, Woo YS, Lee JY, Kim HS, Kim HJ, Cho S, Won NH, Sohn J. Signaling pathway for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages. Exp Mol Med. 2007 Aug 31;39(4):524-34. doi: 10.1038/emm.2007.58. PubMed PMID: 17934341.

select

Cheon H, Rho YH, Choi SJ, Lee YH, Song GG, Sohn J, Won NH, Ji JD. Prostaglandin E2 augments IL-10 signaling and function. J Immunol. 2006 Jul 15;177(2):1092-100. doi: 10.4049/jimmunol.177.2.1092. PubMed PMID: 16818766.

select

Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon H, Um JW, Sohn J, Song GG, Ji JD. 15-Deoxy-delta12,14-PGJ2 inhibits IL-6-induced Stat3 phosphorylation in lymphocytes. Exp Mol Med. 2005 Jun 30;37(3):179-85. doi: 10.1038/emm.2005.24. PubMed PMID: 16000871.

select

Ji JD, Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon HJ, Sohn J, Song GG. Inhibition of IL-10-induced STAT3 activation by 15-deoxy-Delta12,14-prostaglandin J2. Rheumatology (Oxford). 2005 Aug;44(8):983-8. doi: 10.1093/rheumatology/keh657. Epub 2005 Apr 19. PubMed PMID: 15840591.

select

Cheon H, Boyle DL, Firestein GS. Wnt1 inducible signaling pathway protein-3 regulation and microsatellite structure in arthritis. J Rheumatol. 2004 Nov;31(11):2106-14. PubMed PMID: 15517620.

select

Cheon H, Sun YK, Yu SJ, Lee YH, Ji JD, Song GG, Lee JH, Kim MK, Sohn J. Platelet-derived growth factor-AA increases IL-1beta and IL-8 expression and activates NF-kappaB in rheumatoid fibroblast-like synoviocytes. Scand J Immunol. 2004 Nov;60(5):455-62. doi: 10.1111/j.0300-9475.2004.01505.x. PubMed PMID: 15541037.

select

Chung S, Cho J, Cheon H, Paik S, Lee J. Cloning and characterization of a divergent alpha-tubulin that is expressed specifically in dividing amebae of Naegleria gruberi. Gene. 2002 Jun 26;293(1-2):77-86. doi: 10.1016/s0378-1119(02)00509-7. PubMed PMID: 12137945.

select

Cheon H, Yu SJ, Yoo DH, Chae IJ, Song GG, Sohn J. Increased expression of pro-inflammatory cytokines and metalloproteinase-1 by TGF-beta1 in synovial fibroblasts from rheumatoid arthritis and normal individuals. Clin Exp Immunol. 2002 Mar;127(3):547-52. doi: 10.1046/j.1365-2249.2002.01785.x. PubMed PMID: 11966774; PubMed Central PMCID: PMC1906321.

select

Ji JD, Cheon H, Jun JB, Choi SJ, Kim YR, Lee YH, Kim TH, Chae IJ, Song GG, Yoo DH, Kim SY, Sohn J. Effects of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) on the expression of inflammatory cytokines and apoptosis induction in rheumatoid synovial fibroblasts and monocytes. J Autoimmun. 2001 Nov;17(3):215-21. doi: 10.1006/jaut.2001.0542. PubMed PMID: 11712859.