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Byer SJ, Eckert JM, Brossier NM, Clodfelder-Miller BJ, Turk AN, Carroll AJ, Kappes JC, Zinn KR, Prasain JK, Carroll SL. Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent manner. Neuro Oncol. 2011 Jan;13(1):28-41. doi: 10.1093/neuonc/noq146. Epub 2010 Nov 12. PubMed PMID: 21075781; PubMed Central PMCID: PMC3018903.
Brossier NM, Byer SJ, Peavler LT, Carroll SL. ErbB membrane tyrosine kinase receptors: analyzing migration in a highly complex signaling system.. In: Mukai H, editor. Protein Kinase Technologies New York: Springer; 2012. Chapter 7; p.105-131.
Brossier NM, Carroll SL. Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system. Brain Res Bull. 2012 May 1;88(1):58-71. doi: 10.1016/j.brainresbull.2011.08.005. Epub 2011 Aug 10. Review. PubMed PMID: 21855613; PubMed Central PMCID: PMC3263419.
Kazmi SJ, Byer SJ, Eckert JM, Turk AN, Huijbregts RP, Brossier NM, Grizzle WE, Mikhail FM, Roth KA, Carroll SL. Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis. Am J Pathol. 2013 Mar;182(3):646-67. doi: 10.1016/j.ajpath.2012.11.017. Epub 2013 Jan 13. PubMed PMID: 23321323; PubMed Central PMCID: PMC3586689.
Byer SJ, Brossier NM, Peavler LT, Eckert JM, Watkins S, Roth KA, Carroll SL. Malignant peripheral nerve sheath tumor invasion requires aberrantly expressed EGF receptors and is variably enhanced by multiple EGF family ligands. J Neuropathol Exp Neurol. 2013 Mar;72(3):219-33. doi: 10.1097/NEN.0b013e3182859939. PubMed PMID: 23399900; PubMed Central PMCID: PMC3579504.
Kohli L, Kaza N, Coric T, Byer SJ, Brossier NM, Klocke BJ, Bjornsti MA, Carroll SL, Roth KA. 4-Hydroxytamoxifen induces autophagic death through K-Ras degradation. Cancer Res. 2013 Jul 15;73(14):4395-405. doi: 10.1158/0008-5472.CAN-12-3765. Epub 2013 May 30. PubMed PMID: 23722551; PubMed Central PMCID: PMC3715566.
Brosius SN, Turk AN, Byer SJ, Brossier NM, Kohli L, Whitmire A, Mikhail FM, Roth KA, Carroll SL. Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis. Acta Neuropathol. 2014 Apr;127(4):573-91. doi: 10.1007/s00401-013-1209-3. PubMed PMID: 24232507; PubMed Central PMCID: PMC3999224.
Brossier NM, Gutmann DH. Improving outcomes for neurofibromatosis 1-associated brain tumors. Expert Rev Anticancer Ther. 2015 Apr;15(4):415-23. doi: 10.1586/14737140.2015.1009043. Epub 2015 Feb 5. Review. PubMed PMID: 25652347.
Brossier NM, Prechtl AM, Longo JF, Barnes S, Wilson LS, Byer SJ, Brosius SN, Carroll SL. Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells. J Neuropathol Exp Neurol. 2015 Jun;74(6):568-86. doi: 10.1097/NEN.0000000000000201. PubMed PMID: 25946318; PubMed Central PMCID: PMC4433624.
Armstrong AE, Brossier NM, Hirbe AC. Neurofibromatosis type 1-related tumours in paediatrics: an evolving treatment landscape. Lancet Child Adolesc Health. 2020 Jul;4(7):488-490. doi: 10.1016/S2352-4642(20)30169-3. PubMed PMID: 32562630.
Brossier NM, Thondapu S, Cobb OM, Dahiya S, Gutmann DH. Temporal, spatial, and genetic constraints contribute to the patterning and penetrance of murine neurofibromatosis-1 optic glioma. Neuro Oncol. 2021 Apr 12;23(4):625-637. doi: 10.1093/neuonc/noaa237. PubMed PMID: 33080011; PubMed Central PMCID: PMC8041339.
Weber SM, Brossier NM, Prechtl A, Barnes S, Wilson LS, Brosius SN, Longo JF, Carroll SL. R-Ras subfamily proteins elicit distinct physiologic effects and phosphoproteome alterations in neurofibromin-null MPNST cells. Cell Commun Signal. 2021 Sep 16;19(1):95. doi: 10.1186/s12964-021-00773-4. PubMed PMID: 34530870; PubMed Central PMCID: PMC8447793.
Brossier NM, Strahle JM, Cler SJ, Wallendorf M, Gutmann DH. Children with supratentorial midline pilocytic astrocytomas exhibit multiple progressions and acquisition of neurologic deficits over time. Neurooncol Adv. 2022 Jan-Dec;4(1):vdab187. doi: 10.1093/noajnl/vdab187. eCollection 2022 Jan-Dec. PubMed PMID: 35036914; PubMed Central PMCID: PMC8757579.
Cantor E, Meyer A, Morris SM, Weisenberg JLZ, Brossier NM. Dose-dependent seizure control with MEK inhibitor therapy for progressive glioma in a child with neurofibromatosis type 1. Childs Nerv Syst. 2022 Nov;38(11):2245-2249. doi: 10.1007/s00381-022-05571-y. Epub 2022 Jun 1. PubMed PMID: 35648241; PubMed Central PMCID: PMC9617819.
Irshad K, Brossier NM, Pan Y. Neuronal Activity in Brain Tumor Pathogenesis: Adding to the Complexities of Central Nervous System Neoplasia. In: Amit M, Scheff NN, editors. Cancer Neuroscience Cham: Springer; 2023.
Cantor E, Berkovich R, Navalkele P, Brossier NM. Rapid symptomatic improvement in two patients with ganglioglioma after restarting BRAF inhibitor therapy. Pediatr Blood Cancer. 2023 Jul;70(7):e30296. doi: 10.1002/pbc.30296. Epub 2023 Mar 14. PubMed PMID: 36916822; PubMed Central PMCID: PMC10500853.
Gupta A, Lechpammer M, Brossier NM. Germline BRCA2 pathogenic variants in pediatric ganglioglioma: Case report and review of the literature. Childs Nerv Syst. 2024 May;40(5):1609-1612. doi: 10.1007/s00381-023-06267-7. Epub 2024 Jan 3. Review. PubMed PMID: 38168858.
Martin GE, Chan A, Brossier NM. Concurrent Collection of Fetal Murine Brain and Serum to Assess Effects of Maternal Diet on Nutrition and Neurodevelopment in Neurofibromatosis Type 1. J Vis Exp. 2024 May 17;(207). doi: 10.3791/66226. PubMed PMID: 38829109.
Chen Y, Buchanan P, Brossier NM, Navalkele P. Incidence and survival characteristics of pediatric ganglioglioma from 2004 to 2018, with focus on infratentorial sites. Neurooncol Pract. 2024 Jun;11(3):328-335. doi: 10.1093/nop/npae012. eCollection 2024 Jun. PubMed PMID: 38737603; PubMed Central PMCID: PMC11085854.
Chan A, Zhang K, Martin G, Bano S, Chatterjee J, Mahto S, Wang A, Gutmann DH, Brossier NM. Maternal obesogenic diet operates at the tumor cell of origin to increase incidence and decrease latency of Neurofibromatosis Type 1 optic pathway glioma. Neuro Oncol. 2024 Jul 18;. doi: 10.1093/neuonc/noae136. [Epub ahead of print] PubMed PMID: 39023130.
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