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Osmotic pressure measurement device and measurement method. Italy T02006A000508. 2006.
Dispositivo perfezionato di misura della pressione osmotica e relative procedimento di misura. Italy TO2007A000177. 2007.
Grattoni A, Merlo M, Ferrari M. Osmotic pressure beyond concentration restrictions. J Phys Chem B. 2007 Oct 11;111(40):11770-5. doi: 10.1021/jp075834j. Epub 2007 Sep 19. PubMed PMID: 17880133.
Grattoni A, Canavese G, Montevecchi FM, Ferrari M. Fast membrane osmometer as alternative to freezing point and vapor pressure osmometry. Anal Chem. 2008 Apr 1;80(7):2617-22. doi: 10.1021/ac7023987. Epub 2008 Mar 4. PubMed PMID: 18315010.
Yaroshchuk A. Comment on "Osmotic pressure beyond concentration restrictions". J Phys Chem B. 2008 Dec 11;112(49):15941-2; discussion 15943. doi: 10.1021/jp8031995. PubMed PMID: 19367952.
Quality Control Method and Micro/Nano-channeled Devices. USA patent application PCT/US2009/041957. 2009.
Grattoni A, De Rosa E, Ferrati S, Wang Z, Gianesini A, Liu X, Hussain F, Goodall R, Ferrari M. Analysis of a nanochanneled membrane structure through convective gas flow. Journal of Micromechanics and Microengineering. 2009; 19(11):115018-115029. doi: 10.1088/0960-1317/19/11/115018.
Grattoni A, Liu X, Wang Z, Gill J, Ziemys A, Ferrari M. Electrokinetic Transport of Molecules Through Nanochanneled Membranes. Proceedings of the ... ASME Design Engineering Technical Conferences. ASME Design Engineering Technical Conferences. 2010; 43925:131-134. doi: 10.1115/NEMB2010-13236.
Godin B, Sakamoto JH, Serda RE, Grattoni A, Bouamrani A, Ferrari M. Emerging applications of nanomedicine for the diagnosis and treatment of cardiovascular diseases. Trends Pharmacol Sci. 2010 May;31(5):199-205. doi: 10.1016/ Epub 2010 Feb 19. Review. PubMed PMID: 20172613; PubMed Central PMCID: PMC2862836.
Grattoni A, Fine D, Ziemys A, Gill J, Zabre E, Goodall R, Ferrari M. Nanochannel systems for personalized therapy and laboratory diagnostics. Curr Pharm Biotechnol. 2010 Jun;11(4):343-65. doi: 10.2174/138920110791233280. Review. PubMed PMID: 20199382.
Sakamoto JH, van de Ven AL, Godin B, Blanco E, Serda RE, Grattoni A, Ziemys A, Bouamrani A, Hu T, Ranganathan SI, De Rosa E, Martinez JO, Smid CA, Buchanan RM, Lee SY, Srinivasan S, Landry M, Meyn A, Tasciotti E, Liu X, Decuzzi P, Ferrari M. Enabling individualized therapy through nanotechnology. Pharmacol Res. 2010 Aug;62(2):57-89. doi: 10.1016/j.phrs.2009.12.011. Epub 2010 Jan 5. Review. PubMed PMID: 20045055; PubMed Central PMCID: PMC2886806.
Ziemys A, Grattoni A, Fine D, Hussain F, Ferrari M. Confinement effects on monosaccharide transport in nanochannels. J Phys Chem B. 2010 Sep 2;114(34):11117-26. doi: 10.1021/jp103519d. PubMed PMID: 20738139.
Fine D, Grattoni A, Hosali S, Ziemys A, De Rosa E, Gill J, Medema R, Hudson L, Kojic M, Milosevic M, Brousseau Iii L, Goodall R, Ferrari M, Liu X. A robust nanofluidic membrane with tunable zero-order release for implantable dose specific drug delivery. Lab Chip. 2010 Nov 21;10(22):3074-83. doi: 10.1039/c0lc00013b. Epub 2010 Aug 10. PubMed PMID: 20697650.
Sprintz M, Tasciotti E, Allegri M, Grattoni A, Driver LC, Ferrari M. Acute and Chronic Pain: Where we are and where we have to go Nanomedicine: ushering in a new era of pain management. European Journal of Pain Supplements. 2011; 5(2):317-322.
Grattoni A, Parazynski S, Hussain F. NanoGlands: NanoFluidic Implants for Personalized Medicine. ASME Mechanical Engineering. 2011; 133(2):23-26.
Ziemys A, Kojic M, Milosevic M, Kojic N, Hussain F, Ferrari M, Grattoni A. Hierarchical modeling of diffusive transport through nanochannels by coupling molecular dynamics with finite element method. Journal of Computational Physics. 2011; 230:5722-5731.
Grattoni A, Shen H, Fine D, Ziemys A, Gill JS, Hudson L, Hosali S, Goodall R, Liu X, Ferrari M. Nanochannel technology for constant delivery of chemotherapeutics: beyond metronomic administration. Pharm Res. 2011 Feb;28(2):292-300. doi: 10.1007/s11095-010-0195-6. Epub 2010 Jul 1. PubMed PMID: 20593302.
Grattoni A, Gill J, Zabre E, Fine D, Hussain F, Ferrari M. Device for rapid and agile measurement of diffusivity in micro- and nanochannels. Anal Chem. 2011 Apr 15;83(8):3096-103. doi: 10.1021/ac1033648. Epub 2011 Mar 24. PubMed PMID: 21434670.
Fine D, Grattoni A, Zabre E, Hussein F, Ferrari M, Liu X. A low-voltage electrokinetic nanochannel drug delivery system. Lab Chip. 2011 Aug 7;11(15):2526-34. doi: 10.1039/c1lc00001b. Epub 2011 Jun 15. PubMed PMID: 21677944.
Grattoni A, Fine D, Zabre E, Ziemys A, Gill J, Mackeyev Y, Cheney MA, Danila DC, Hosali S, Wilson LJ, Hussain F, Ferrari M. Gated and near-surface diffusion of charged fullerenes in nanochannels. ACS Nano. 2011 Dec 27;5(12):9382-91. doi: 10.1021/nn2037863. Epub 2011 Nov 14. PubMed PMID: 22032773.
Grattoni A, Tasciotti E, Fine D, Fernandez-Moure JS, Sakamoto J, Hu Y, Weiner B, Ferrari M, Parazynski S. Nanotechnologies and regenerative medical approaches for space and terrestrial medicine. Aviat Space Environ Med. 2012 Nov;83(11):1025-36. doi: 10.3357/asem.3307.2012. Review. PubMed PMID: 23156089.
Nanochanneled Device and Related Methods. USA patent application 13/264,069. 2013.
Pimpinelli A, Ferrari M, Grattoni A. Scaling and crossovers in molecular transport in nano-fluidic systems. Applied physics letters. 2013; 103(11):113104-113108. doi: 10.1063/1.4819156.
Nanochanneled device and related methods. USA 8,480,637. 2013.
Sustained Drug Delivery From Solid Implants with Nanochannel Membranes. USA patent application PCT/US2013/022987. 2013.
Device and Method for Sustained Release of Therapeutic Agent. USA patent application 13/659,064. 2013.
Nanochanneled Device and Related Methods. USA patent application 13/698,926. 2013.
Sih J, Bansal SS, Filippini S, Ferrati S, Raghuwansi K, Zabre E, Nicolov E, Fine D, Ferrari M, Palapattu G, Grattoni A. Characterization of nanochannel delivery membrane systems for the sustained release of resveratrol and atorvastatin: new perspectives on promoting heart health. Anal Bioanal Chem. 2013 Feb;405(5):1547-57. doi: 10.1007/s00216-012-6484-7. Epub 2012 Oct 23. PubMed PMID: 23090650.
Fine D, Grattoni A, Goodall R, Bansal SS, Chiappini C, Hosali S, van de Ven AL, Srinivasan S, Liu X, Godin B, Brousseau L 3rd, Yazdi IK, Fernandez-Moure J, Tasciotti E, Wu HJ, Hu Y, Klemm S, Ferrari M. Silicon micro- and nanofabrication for medicine. Adv Healthc Mater. 2013 May;2(5):632-66. doi: 10.1002/adhm.201200214. Epub 2013 Apr 15. Review. PubMed PMID: 23584841; PubMed Central PMCID: PMC3777663.
Bansal SS, Celia C, Ferrati S, Zabre E, Ferrari M, Palapattu G, Grattoni A. Validated RP-HPLC method for the simultaneous analysis of gemcitabine and LY-364947 in liposomal formulations. Curr Drug Targets. 2013 Aug;14(9):1061-9. doi: 10.2174/13894501113149990165. PubMed PMID: 23721184.
Sarpietro MG, Accolla ML, Celia C, Grattoni A, Castelli F, Fresta M, Ferrari M, Paolino D. Differential scanning calorimetry as a tool to investigate the transfer of anticancer drugs to biomembrane model. Curr Drug Targets. 2013 Aug;14(9):1053-60. doi: 10.2174/1389450111314090013. PubMed PMID: 23651164.
Sabek OM, Ferrati S, Fraga DW, Sih J, Zabre EV, Fine DH, Ferrari M, Gaber AO, Grattoni A. Characterization of a nanogland for the autotransplantation of human pancreatic islets. Lab Chip. 2013 Sep 21;13(18):3675-88. doi: 10.1039/c3lc50601k. PubMed PMID: 23884326.
Ferrati S, Fine D, You J, De Rosa E, Hudson L, Zabre E, Hosali S, Zhang L, Hickman C, Sunder Bansal S, Cordero-Reyes AM, Geninatti T, Sih J, Goodall R, Palapattu G, Kloc M, Ghobrial RM, Ferrari M, Grattoni A. Leveraging nanochannels for universal, zero-order drug delivery in vivo. J Control Release. 2013 Dec 28;172(3):1011-9. doi: 10.1016/j.jconrel.2013.09.028. Epub 2013 Oct 3. PubMed PMID: 24095805.
Anderson JR, Ferrati S, Karmonik C, Grattoni A. Functional validation of an implantable medical dosing device by MRI at 3T. Annu Int Conf IEEE Eng Med Biol Soc. 2014;2014:2346-7. doi: 10.1109/EMBC.2014.6944091. PubMed PMID: 25570459.
Nicolov E, Ferrati S, Goodall R, Hudson L, Hosali S, Crowley M, Palapattu G, Khera M, Grattoni A. Nanotechnology-based Implant for Long Term Testosterone Replacement. The Journal of urology. 2014; 191(4):e485–e486. doi: 10.1016/j.juro.2014.02.1177.
Geninatti T, Small E, Grattoni A. Robotic UV-Vis apparatus for long-term characterization of drug release from nanochannels. Measurement Science and Technology. 2014; 25(2):027003. doi: 10.1088/0957-0233/25/2/027003.
Celia C, Ferrati S, Bansal S, van de Ven AL, Ruozi B, Zabre E, Hosali S, Paolino D, Sarpietro MG, Fine D, Fresta M, Ferrari M, Grattoni A. Sustained zero-order release of intact ultra-stable drug-loaded liposomes from an implantable nanochannel delivery system. Adv Healthc Mater. 2014 Feb;3(2):230-8. doi: 10.1002/adhm.201300188. Epub 2013 Jul 23. PubMed PMID: 23881575; PubMed Central PMCID: PMC3970317.
Ferrati S, Nicolov E, Bansal S, Hosali S, Landis M, Grattoni A. Docetaxel/2-Hydroxypropyl β -Cyclodextrin Inclusion Complex Increases Docetaxel Solubility and Release from a Nanochannel Drug Delivery System. Curr Drug Targets. 2015;16(14):1645-9. doi: 10.2174/138945011614151119125541. PubMed PMID: 25706254.
Nanochanneled Device with Electrodes and Related Methods. USA patent application 61/861,070. 2015.
Geninatti T, Bruno G, Barile B, Hood RL, Farina M, Schmulen J, Canavese G, Grattoni A. Impedance characterization, degradation, and in vitro biocompatibility for platinum electrodes on BioMEMS. Biomed Microdevices. 2015 Feb;17(1):24. doi: 10.1007/s10544-014-9909-6. PubMed PMID: 25663443; PubMed Central PMCID: PMC4489853.
Ferrati S, Nicolov E, Bansal S, Zabre E, Geninatti T, Ziemys A, Hudson L, Ferrari M, Goodall R, Khera M, Palapattu G, Grattoni A. Delivering enhanced testosterone replacement therapy through nanochannels. Adv Healthc Mater. 2015 Feb 18;4(3):446-51. doi: 10.1002/adhm.201400348. Epub 2014 Oct 1. PubMed PMID: 25274059.
Bruno G, Geninatti T, Hood RL, Fine D, Scorrano G, Schmulen J, Hosali S, Ferrari M, Grattoni A. Leveraging electrokinetics for the active control of dendritic fullerene-1 release across a nanochannel membrane. Nanoscale. 2015 Mar 12;7(12):5240-8. doi: 10.1039/c4nr06209d. PubMed PMID: 25707848; PubMed Central PMCID: PMC4386861.
Ferrati S, Nicolov E, Zabre E, Geninatti T, Shirkey BA, Hudson L, Hosali S, Crawley M, Khera M, Palapattu G, Grattoni A. The nanochannel delivery system for constant testosterone replacement therapy. J Sex Med. 2015 Jun;12(6):1375-80. doi: 10.1111/jsm.12897. Epub 2015 Apr 30. PubMed PMID: 25930087.
Geninatti T, Hood RL, Bruno G, Jain P, Nicolov E, Ziemys A, Grattoni A. Sustained Administration of Hormones Exploiting Nanoconfined Diffusion through Nanochannel Membranes. Materials (Basel). 2015 Aug;8(8):5276-5288. doi: 10.3390/ma8085241. Epub 2015 Aug 13. PubMed PMID: 27293533; PubMed Central PMCID: PMC4898476.
Ballerini A, Filgueira CS, Nicolov E, Jain P, Bruno G, Hood RL, Scaglione F, Grattoni A. Sustained Delivery of Tamoxifen from a Nanofluidic Delivery Platform. Drug delivery letters. 2016; 6(2):127-133. doi: 10.2174/2210303106666161129163850.
Sabek OM, Farina 23, Fraga DW, Afshar S, Ballerini A, Filgueira CS, Thekkedath UR, Grattoni A, Gaber AO. 3D printed encapsulation system for human mesenchymal stem cells differentiated into islet-like insulin producing aggregates for diabetes treatment. J Tissue Eng.. 2016; 7:2041731416638198. doi: 10.1177/2041731416638198.
Tasciotti E, Cabrera FJ, Evangelopoulos M, Martinez JO, Thekkedath UR, Kloc M, Ghobrial RM, Li XC, Grattoni A, Ferrari M. The Emerging Role of Nanotechnology in Cell and Organ Transplantation. Transplantation. 2016 Aug;100(8):1629-38. doi: 10.1097/TP.0000000000001100. Review. PubMed PMID: 27257995; PubMed Central PMCID: PMC4961523.
Hood RL, Bruno G, Jain P, Anderson J, Wolfe T, Quini C, Schmulen J, Li XC, Butler EB, Krishnan S, Grattoni A. Nanochannel Implants for Minimally-Invasive Insertion and Intratumoral Delivery. J Biomed Nanotechnol. 2016 Oct;12(10):1907-15. doi: 10.1166/jbn.2016.2288. PubMed PMID: 29360309.
Filgueira CS, Nicolov E, Hood RL, Ballerini A, Garcia-Huidobro J, Lin JZ, Fraga D, Webb P, Sabek OM, Gaber AO, Phillips KJ, Grattoni A. Sustained zero-order delivery of GC-1 from a nanochannel membrane device alleviates metabolic syndrome. Int J Obes (Lond). 2016 Nov;40(11):1776-1783. doi: 10.1038/ijo.2016.129. Epub 2016 Jul 27. PubMed PMID: 27460601.
Bruno G, Canavese G, Liu X, Filgueira CS, Sacco A, Demarchi D, Ferrari M, Grattoni A. The active modulation of drug release by an ionic field effect transistor for an ultra-low power implantable nanofluidic system. Nanoscale. 2016 Nov 10;8(44):18718-18725. doi: 10.1039/c6nr06235k. PubMed PMID: 27787528; PubMed Central PMCID: PMC5166607.
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