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Miller DR, Bu M, Gopinath A, Martinez LR, Khoshbouei H. Methamphetamine Dysregulation of the Central Nervous System and Peripheral Immunity. J Pharmacol Exp Ther. 2021 Dec;379(3):372-385. doi: 10.1124/jpet.121.000767. Epub 2021 Sep 17. Review. PubMed PMID: 34535563.
Pires RH, Martinez LR, Mendes-Giannini MJS, Stoianoff MAR. Editorial: Pathogenesis of Fungal Biofilms in Different Environmental Conditions and Clinical Outcomes. Front Cell Infect Microbiol. 2021;11:778458. doi: 10.3389/fcimb.2021.778458. eCollection 2021. PubMed PMID: 34746037; PubMed Central PMCID: PMC8566804.
Costa-Orlandi CB, Martinez LR, Bila NM, Friedman JM, Friedman AJ, Mendes-Giannini MJS, Nosanchuk JD. Nitric Oxide-Releasing Nanoparticles Are Similar to Efinaconazole in Their Capacity to Eradicate Trichophyton rubrum Biofilms. Front Cell Infect Microbiol. 2021;11:684150. doi: 10.3389/fcimb.2021.684150. eCollection 2021. PubMed PMID: 34336712; PubMed Central PMCID: PMC8319823.
Hernandez-Santini AC, Mitha AN, Chow D, Hamed MF, Gucwa AL, Vaval V, Martinez LR. Methamphetamine facilitates pulmonary and splenic tissue injury and reduces T cell infiltration in C57BL/6 mice after antigenic challenge. Sci Rep. 2021 Apr 15;11(1):8207. doi: 10.1038/s41598-021-87728-4. PubMed PMID: 33859291; PubMed Central PMCID: PMC8050260.
Mitha AN, Chow D, Vaval V, Guerrero P, Rivera-Rodriguez DE, Martinez LR. Methamphetamine Compromises the Adaptive B Cell-Mediated Immunity to Antigenic Challenge in C57BL/6 Mice. Front Toxicol. 2021 Mar;3. doi: 10.3389/ftox.2021.629451. Epub 2021 Mar 15. PubMed PMID: 34109323; PubMed Central PMCID: PMC8186300.
Lee HH, Sudhakara P, Desai S, Miranda K, Martinez LR. Understanding the Basis of METH Mouth Using a Rodent Model of Methamphetamine Injection, Sugar Consumption, and Streptococcus mutans Infection. mBio. 2021 Mar 9;12(2). doi: 10.1128/mBio.03534-20. PubMed PMID: 33688011; PubMed Central PMCID: PMC8092307.
Woo YH, Martinez LR. Cryptococcus neoformans-astrocyte interactions: effect on fungal blood brain barrier disruption, brain invasion, and meningitis progression. Crit Rev Microbiol. 2021 Mar;47(2):206-223. doi: 10.1080/1040841X.2020.1869178. Epub 2021 Jan 21. Review. PubMed PMID: 33476528; PubMed Central PMCID: PMC8018722.
Belisario JC, Lee HH, Luknauth H, Rigel NW, Martinez LR. Acinetobacter baumannii Strains Deficient in the Clp Chaperone-Protease Genes Have Reduced Virulence in a Murine Model of Pneumonia. Pathogens. 2021 Feb 13;10(2). doi: 10.3390/pathogens10020204. PubMed PMID: 33668542; PubMed Central PMCID: PMC7917692.
Mancini JD, Yao S, Martinez LR, Shakil H, Li TS. Gut Microbiome Changes with Osteopathic Treatment of Constipation in Parkinson's Disease: A Pilot Study. Neurology (ECronicon). 2021 Feb;13(2):19-33. Epub 2021 Jan 30. PubMed PMID: 33899052; PubMed Central PMCID: PMC8061899.
Pruksaphon K, Ching MMN, Nosanchuk JD, Kaltsas A, Ratanabanangkoon K, Roytrakul S, Martinez LR, Youngchim S. Characterization of a novel yeast phase-specific antigen expressed during in vitro thermal phase transition of Talaromyces marneffei. Sci Rep. 2020 Dec 3;10(1):21169. doi: 10.1038/s41598-020-78178-5. PubMed PMID: 33273617; PubMed Central PMCID: PMC7713699.
Lee HH, Aslanyan L, Vidyasagar A, Brennan MB, Tauber MS, Carrillo-Sepulveda MA, Dores MR, Rigel NW, Martinez LR. Depletion of Alveolar Macrophages Increases Pulmonary Neutrophil Infiltration, Tissue Damage, and Sepsis in a Murine Model of Acinetobacter baumannii Pneumonia. Infect Immun. 2020 Jun 22;88(7). doi: 10.1128/IAI.00128-20. Print 2020 Jun 22. PubMed PMID: 32366576; PubMed Central PMCID: PMC7309625.
Vargas AM, Rivera-Rodriguez DE, Martinez LR. Methamphetamine alters the TLR4 signaling pathway, NF-κB activation, and pro-inflammatory cytokine production in LPS-challenged NR-9460 microglia-like cells. Mol Immunol. 2020 May;121:159-166. doi: 10.1016/j.molimm.2020.03.013. Epub 2020 Mar 26. PubMed PMID: 32222586; PubMed Central PMCID: PMC8079139.
Azzam SZ, Cayme GJ, Martinez LR. Polymicrobial interactions involving fungi and their importance for the environment and in human disease. Microb Pathog. 2020 Mar;140:103942. doi: 10.1016/j.micpath.2019.103942. Epub 2019 Dec 24. Review. PubMed PMID: 31881258; PubMed Central PMCID: PMC7105396.
Han G, Havnaer A, Lee HH, Carmichael DJ, Martinez LR. Biological depletion of neutrophils attenuates pro-inflammatory markers and the development of the psoriatic phenotype in a murine model of psoriasis. Clin Immunol. 2020 Jan;210:108294. doi: 10.1016/j.clim.2019.108294. Epub 2019 Oct 31. PubMed PMID: 31678366; PubMed Central PMCID: PMC8043213.
Lee HH, Del Pozzo J, Salamanca SA, Hernandez H, Martinez LR. Reduced phagocytosis and killing of Cryptococcus neoformans biofilm-derived cells by J774.16 macrophages is associated with fungal capsular production and surface modification. Fungal Genet Biol. 2019 Nov;132:103258. doi: 10.1016/j.fgb.2019.103258. Epub 2019 Jul 26. PubMed PMID: 31356873; PubMed Central PMCID: PMC6905497.
DiCaro D, Lee HH, Belisario C, Ramos RL, Martinez LR. Combination of acute intravenous methamphetamine injection and LPS challenge facilitate leukocyte infiltration into the central nervous system of C57BL/6 mice. Int Immunopharmacol. 2019 Oct;75:105751. doi: 10.1016/j.intimp.2019.105751. Epub 2019 Jul 15. PubMed PMID: 31319359; PubMed Central PMCID: PMC6905393.
Hernandez H, Erives VH, Martinez LR. Coccidioidomycosis: Epidemiology, Fungal Pathogenesis, and Therapeutic Development. Curr Trop Med Rep. 2019 Sep 15;6(3):132-144. doi: 10.1007/s40475-019-00184-z. Epub 2019 Jun 14. PubMed PMID: 34367879; PubMed Central PMCID: PMC8340492.
Guimarães AJ, de Cerqueira MD, Zamith-Miranda D, Lopez PH, Rodrigues ML, Pontes B, Viana NB, DeLeon-Rodriguez CM, Rossi DCP, Casadevall A, Gomes AMO, Martinez LR, Schnaar RL, Nosanchuk JD, Nimrichter L. Host membrane glycosphingolipids and lipid microdomains facilitate Histoplasma capsulatum internalisation by macrophages. Cell Microbiol. 2019 Mar;21(3):e12976. doi: 10.1111/cmi.12976. Epub 2018 Dec 7. PubMed PMID: 30427108; PubMed Central PMCID: PMC6805151.
Sanchez DA, Martinez LR. Underscoring interstrain variability and the impact of growth conditions on associated antimicrobial susceptibilities in preclinical testing of novel antimicrobial drugs. Crit Rev Microbiol. 2019 Feb;45(1):51-64. doi: 10.1080/1040841X.2018.1538934. Epub 2018 Dec 6. Review. PubMed PMID: 30522365; PubMed Central PMCID: PMC6905375.
Aslanyan L, Lee HH, Ekhar VV, Ramos RL, Martinez LR. Methamphetamine Impairs IgG1-Mediated Phagocytosis and Killing of Cryptococcus neoformans by J774.16 Macrophage- and NR-9640 Microglia-Like Cells. Infect Immun. 2019 Feb;87(2). doi: 10.1128/IAI.00113-18. Print 2019 Feb. PubMed PMID: 30510106; PubMed Central PMCID: PMC6346126.
Gwin CM, Prakash N, Christian Belisario J, Haider L, Rosen ML, Martinez LR, Rigel NW. The apolipoprotein N-acyl transferase Lnt is dispensable for growth in Acinetobacter species. Microbiology (Reading). 2018 Dec;164(12):1547-1556. doi: 10.1099/mic.0.000726. Epub 2018 Oct 11. PubMed PMID: 30307391; PubMed Central PMCID: PMC7008215.
Martinez LR, Boucaud DW, Casadevall A, August A. Factors Contributing to the Success of NIH-Designated Underrepresented Minorities in Academic and Nonacademic Research Positions. CBE Life Sci Educ. 2018 Jun;17(2):ar32. doi: 10.1187/cbe.16-09-0287. PubMed PMID: 29799320; PubMed Central PMCID: PMC5998319.
Hernandez H, Martinez LR. Relationship of environmental disturbances and the infectious potential of fungi. Microbiology (Reading). 2018 Mar;164(3):233-241. doi: 10.1099/mic.0.000620. Epub 2018 Feb 5. Review. PubMed PMID: 29458659; PubMed Central PMCID: PMC5885008.
Ramos RL, Guercio E, Martinez LR. Pre-Medical Preparation in Microbiology among Applicants and Matriculants in Osteopathic Medical School in the United States. J Microbiol Biol Educ. 2017;18(3). doi: 10.1128/jmbe.v18i3.1372. eCollection 2017. PubMed PMID: 29854054; PubMed Central PMCID: PMC5976050.
Ramos RL, Alviña K, Martinez LR. Diversity of Graduates from Bachelor's, Master's and Doctoral Degree Neuroscience Programs in the United States. J Undergrad Neurosci Educ. 2017 Fall;16(1):A6-A13. eCollection 2017 Fall. PubMed PMID: 29371835; PubMed Central PMCID: PMC5777839.
Zhang L, Wiles C, Martinez LR, Han G. Neutrophil-to-lymphocyte ratio decreases after treatment of psoriasis with therapeutic antibodies. J Eur Acad Dermatol Venereol. 2017 Nov;31(11):e491-e492. doi: 10.1111/jdv.14334. Epub 2017 Jul 3. PubMed PMID: 28502119; PubMed Central PMCID: PMC5685943.
Koutsouras GW, Ramos RL, Martinez LR. Role of microglia in fungal infections of the central nervous system. Virulence. 2017 Aug 18;8(6):705-718. doi: 10.1080/21505594.2016.1261789. Epub 2016 Nov 18. Review. PubMed PMID: 27858519; PubMed Central PMCID: PMC5626199.
Aslanyan L, Ekhar VV, DeLeon-Rodriguez CM, Martinez LR. Capsular specific IgM enhances complement-mediated phagocytosis and killing of Cryptococcus neoformans by methamphetamine-treated J774.16 macrophage-like cells. Int Immunopharmacol. 2017 Aug;49:77-84. doi: 10.1016/j.intimp.2017.05.024. Epub 2017 May 25. PubMed PMID: 28551495; PubMed Central PMCID: PMC5599138.
Aslanyan L, Sanchez DA, Valdebenito S, Eugenin EA, Ramos RL, Martinez LR. The Crucial Role of Biofilms in Cryptococcus neoformans Survival within Macrophages and Colonization of the Central Nervous System. J Fungi (Basel). 2017 Feb 24;3(1). doi: 10.3390/jof3010010. Review. PubMed PMID: 29371529; PubMed Central PMCID: PMC5715963.
Mihu MR, Cabral V, Pattabhi R, Tar MT, Davies KP, Friedman AJ, Martinez LR, Nosanchuk JD. Sustained Nitric Oxide-Releasing Nanoparticles Interfere with Methicillin-Resistant Staphylococcus aureus Adhesion and Biofilm Formation in a Rat Central Venous Catheter Model. Antimicrob Agents Chemother. 2017 Jan;61(1). doi: 10.1128/AAC.02020-16. Print 2017 Jan. PubMed PMID: 27821454; PubMed Central PMCID: PMC5192117.
Delfiner MS, Martinez LR, Pavia CS. A Gram Stain Hands-On Workshop Enhances First Year Medical Students' Technique Competency in Comprehension and Memorization. PLoS One. 2016;11(10):e0163658. doi: 10.1371/journal.pone.0163658. eCollection 2016. PubMed PMID: 27711118; PubMed Central PMCID: PMC5053596.
Castellano P, Nwagbo C, Martinez LR, Eugenin EA. Methamphetamine compromises gap junctional communication in astrocytes and neurons. J Neurochem. 2016 May;137(4):561-75. doi: 10.1111/jnc.13603. Epub 2016 Apr 18. PubMed PMID: 26953131; PubMed Central PMCID: PMC5050922.
Ahmadi MS, Lee HH, Sanchez DA, Friedman AJ, Tar MT, Davies KP, Nosanchuk JD, Martinez LR. Sustained Nitric Oxide-Releasing Nanoparticles Induce Cell Death in Candida albicans Yeast and Hyphal Cells, Preventing Biofilm Formation In Vitro and in a Rodent Central Venous Catheter Model. Antimicrob Agents Chemother. 2016 Apr;60(4):2185-94. doi: 10.1128/AAC.02659-15. Print 2016 Apr. PubMed PMID: 26810653; PubMed Central PMCID: PMC4808184.
Shah HR, Martinez LR. Current Approaches in Implementing Citizen Science in the Classroom. J Microbiol Biol Educ. 2016 Mar;17(1):17-22. doi: 10.1128/jmbe.v17i1.1032. eCollection 2016 Mar. PubMed PMID: 27047583; PubMed Central PMCID: PMC4798802.
Cordero RJ, Liedke SC, de S Araújo GR, Martinez LR, Nimrichter L, Frases S, Peralta JM, Casadevall A, Rodrigues ML, Nosanchuk JD, Guimaraes AJ. Enhanced virulence of Histoplasma capsulatum through transfer and surface incorporation of glycans from Cryptococcus neoformans during co-infection. Sci Rep. 2016 Feb 24;6:21765. doi: 10.1038/srep21765. PubMed PMID: 26908077; PubMed Central PMCID: PMC4764860.
Krishnamoorthy S, Shah BP, Lee HH, Martinez LR. Microbicides Alter the Expression and Function of RND-Type Efflux Pump AdeABC in Biofilm-Associated Cells of Acinetobacter baumannii Clinical Isolates. Antimicrob Agents Chemother. 2016 Jan;60(1):57-63. doi: 10.1128/AAC.01045-15. Print 2016 Jan. PubMed PMID: 26459900; PubMed Central PMCID: PMC4704159.
Mihu MR, Roman-Sosa J, Varshney AK, Eugenin EA, Shah BP, Ham Lee H, Nguyen LN, Guimaraes AJ, Fries BC, Nosanchuk JD, Martinez LR. Methamphetamine Alters the Antimicrobial Efficacy of Phagocytic Cells during Methicillin-Resistant Staphylococcus aureus Skin Infection. mBio. 2015 Oct 27;6(6):e01622-15. doi: 10.1128/mBio.01622-15. PubMed PMID: 26507236; PubMed Central PMCID: PMC4626859.
Grguric-Smith LM, Lee HH, Gandhi JA, Brennan MB, DeLeon-Rodriguez CM, Coelho C, Han G, Martinez LR. Neutropenia exacerbates infection by Acinetobacter baumannii clinical isolates in a murine wound model. Front Microbiol. 2015;6:1134. doi: 10.3389/fmicb.2015.01134. eCollection 2015. PubMed PMID: 26528277; PubMed Central PMCID: PMC4607880.
Martinez LR. Commentary: Role of Sterylglucosidase 1 (Sgl1) on the pathogenicity of Cryptococcus neoformans: potential applications for vaccine development. Front Microbiol. 2015;6:1112. doi: 10.3389/fmicb.2015.01112. eCollection 2015. PubMed PMID: 26500643; PubMed Central PMCID: PMC4599045.
Martinez LR, Casadevall A. Biofilm Formation by Cryptococcus neoformans. Microbiol Spectr. 2015 Jun;3(3). doi: 10.1128/microbiolspec.MB-0006-2014. PubMed PMID: 26185073.
Salamanca SA, Sorrentino EE, Nosanchuk JD, Martinez LR. Impact of methamphetamine on infection and immunity. Front Neurosci. 2014;8:445. doi: 10.3389/fnins.2014.00445. eCollection 2014. Review. PubMed PMID: 25628526; PubMed Central PMCID: PMC4290678.
Abdulkareem AF, Lee HH, Ahmadi M, Martinez LR. Fungal serotype-specific differences in bacterial-yeast interactions. Virulence. 2015;6(6):652-7. doi: 10.1080/21505594.2015.1066962. PubMed PMID: 26132337; PubMed Central PMCID: PMC4720249.
Parisi DN, Martinez LR. Intracellular Haemophilus influenzae invades the brain: is zyxin a critical blood brain barrier component regulated by TNF-α?. Virulence. 2014 Aug 15;5(6):645-7. doi: 10.4161/viru.36086. PubMed PMID: 25127527; PubMed Central PMCID: PMC4139403.
Tar MT, Martinez LR, Nosanchuk JD, Davies KP. The effect of methamphetamine on an animal model of erectile function. Andrology. 2014 Jul;2(4):531-6. doi: 10.1111/j.2047-2927.2014.00212.x. Epub 2014 Apr 3. PubMed PMID: 24706617; PubMed Central PMCID: PMC4151273.
Gandhi JA, Ekhar VV, Asplund MB, Abdulkareem AF, Ahmadi M, Coelho C, Martinez LR. Alcohol enhances Acinetobacter baumannii-associated pneumonia and systemic dissemination by impairing neutrophil antimicrobial activity in a murine model of infection. PLoS One. 2014;9(4):e95707. doi: 10.1371/journal.pone.0095707. eCollection 2014. PubMed PMID: 24752133; PubMed Central PMCID: PMC3994102.
Varshney AK, Wang X, Scharff MD, MacIntyre J, Zollner RS, Kovalenko OV, Martinez LR, Byrne FR, Fries BC. Staphylococcal Enterotoxin B-specific monoclonal antibody 20B1 successfully treats diverse Staphylococcus aureus infections. J Infect Dis. 2013 Dec 15;208(12):2058-66. doi: 10.1093/infdis/jit421. Epub 2013 Aug 6. PubMed PMID: 23922375; PubMed Central PMCID: PMC3836467.
Orsinger-Jacobsen SJ, Patel SS, Vellozzi EM, Gialanella P, Nimrichter L, Miranda K, Martinez LR. Use of a stainless steel washer platform to study Acinetobacter baumannii adhesion and biofilm formation on abiotic surfaces. Microbiology (Reading). 2013 Dec;159(Pt 12):2594-2604. doi: 10.1099/mic.0.068825-0. Epub 2013 Sep 11. PubMed PMID: 24025603; PubMed Central PMCID: PMC3853682.
Manepalli S, Gandhi JA, Ekhar VV, Asplund MB, Coelho C, Martinez LR. Characterization of a cyclophosphamide-induced murine model of immunosuppression to study Acinetobacter baumannii pathogenesis. J Med Microbiol. 2013 Nov;62(Pt 11):1747-1754. doi: 10.1099/jmm.0.060004-0. Epub 2013 Sep 2. PubMed PMID: 24000227; PubMed Central PMCID: PMC4083505.
Eugenin EA, Greco JM, Frases S, Nosanchuk JD, Martinez LR. Methamphetamine alters blood brain barrier protein expression in mice, facilitating central nervous system infection by neurotropic Cryptococcus neoformans. J Infect Dis. 2013 Aug 15;208(4):699-704. doi: 10.1093/infdis/jit117. Epub 2013 Mar 26. PubMed PMID: 23532099; PubMed Central PMCID: PMC3719895.
Asplund MB, Coelho C, Cordero RJ, Martinez LR. Alcohol impairs J774.16 macrophage-like cell antimicrobial functions in Acinetobacter baumannii infection. Virulence. 2013 Aug 15;4(6):467-72. doi: 10.4161/viru.25641. Epub 2013 Jul 10. PubMed PMID: 23863607; PubMed Central PMCID: PMC5359719.
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