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Tewes M, Schleucher N, Achterrath W, Wilke HJ, Frings S, Seeber S, Harstrick A, Rustum YM, Vanhoefer U. Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study. Ann Oncol. 2003 Sep;14(9):1442-8. doi: 10.1093/annonc/mdg376. PubMed PMID: 12954586.
Vanhoefer U, Tewes M, Rojo F, Dirsch O, Schleucher N, Rosen O, Tillner J, Kovar A, Braun AH, Trarbach T, Seeber S, Harstrick A, Baselga J. Phase I study of the humanized antiepidermal growth factor receptor monoclonal antibody EMD72000 in patients with advanced solid tumors that express the epidermal growth factor receptor. J Clin Oncol. 2004 Jan 1;22(1):175-84. doi: 10.1200/JCO.2004.05.114. PubMed PMID: 14701780.
Mross K, Richly H, Schleucher N, Korfee S, Tewes M, Scheulen ME, Seeber S, Beinert T, Schweigert M, Sauer U, Unger C, Behringer D, Brendel E, Haase CG, Voliotis D, Strumberg D. A phase I clinical and pharmacokinetic study of the camptothecin glycoconjugate, BAY 38-3441, as a daily infusion in patients with advanced solid tumors. Ann Oncol. 2004 Aug;15(8):1284-94. doi: 10.1093/annonc/mdh313. PubMed PMID: 15277271.
Strumberg D, Richly H, Hilger RA, Schleucher N, Korfee S, Tewes M, Faghih M, Brendel E, Voliotis D, Haase CG, Schwartz B, Awada A, Voigtmann R, Scheulen ME, Seeber S. Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. J Clin Oncol. 2005 Feb 10;23(5):965-72. doi: 10.1200/JCO.2005.06.124. Epub 2004 Dec 21. PubMed PMID: 15613696.
Tewes M, Aktas B, Welt A, Mueller S, Hauch S, Kimmig R, Kasimir-Bauer S. Molecular profiling and predictive value of circulating tumor cells in patients with metastatic breast cancer: an option for monitoring response to breast cancer related therapies. Breast Cancer Res Treat. 2009 Jun;115(3):581-90. doi: 10.1007/s10549-008-0143-x. Epub 2008 Aug 5. PubMed PMID: 18679793.
Aktas B, Tewes M, Fehm T, Hauch S, Kimmig R, Kasimir-Bauer S. Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients. Breast Cancer Res. 2009;11(4):R46. doi: 10.1186/bcr2333. Epub 2009 Jul 9. PubMed PMID: 19589136; PubMed Central PMCID: PMC2750105.
Aktas B, Müller V, Tewes M, Zeitz J, Kasimir-Bauer S, Loehberg CR, Rack B, Schneeweiss A, Fehm T. Comparison of estrogen and progesterone receptor status of circulating tumor cells and the primary tumor in metastatic breast cancer patients. Gynecol Oncol. 2011 Aug;122(2):356-60. doi: 10.1016/j.ygyno.2011.04.039. Epub 2011 May 24. PubMed PMID: 21605893.
Aktas B, Kasimir-Bauer S, Lehmann N, Kimmig R, Tewes M. Validity of bone marker measurements for monitoring response to bisphosphonate therapy with zoledronic acid in metastatic breast cancer. Oncol Rep. 2013 Jul;30(1):441-7. doi: 10.3892/or.2013.2409. Epub 2013 Apr 22. PubMed PMID: 23604361.
Wiesweg M, Ting S, Reis H, Worm K, Kasper S, Tewes M, Welt A, Richly H, Meiler J, Bauer S, Hense J, Gauler TC, Köhler J, Eberhardt WE, Darwiche K, Freitag L, Stamatis G, Breitenbücher F, Wohlschlaeger J, Theegarten D, Derks C, Cortes-Incio D, Linden G, Skottky S, Lütkes P, Dechêne A, Paul A, Markus P, Schmid KW, Schuler M. Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center. Eur J Cancer. 2013 Oct;49(15):3076-82. doi: 10.1016/j.ejca.2013.06.014. Epub 2013 Jul 19. PubMed PMID: 23876834.
Welt A, Tewes M, Aktas B, O Hoffmann O, Wiesweg M, Ting S, Reis H, Worm K, Richly H, Hense J, Palmer MR, Lee BH, Wendling J, Kossow J, Scheulen ME, Lehnerdt C, Kohl M, Derks C, Skottky S, Haus U, Schmid KW, Kimmig R, Schuler M, Kasper S. Preemptive tumor profiling for biomarker-stratified early clinical drug development in metastatic breast cancer patients. Breast Cancer Res Treat. 2013 Nov;142(1):81-8. doi: 10.1007/s10549-013-2718-4. PubMed PMID: 24122392.
Tewes M, Kasimir-Bauer S, Welt A, Schuler M, Kimmig R, Aktas B. Detection of disseminated tumor cells in bone marrow and circulating tumor cells in blood of patients with early-stage male breast cancer. J Cancer Res Clin Oncol. 2015 Jan;141(1):87-92. doi: 10.1007/s00432-014-1784-2. Epub 2014 Aug 10. PubMed PMID: 25108406.
Bredemeier M, Edimiris P, Tewes M, Mach P, Aktas B, Schellbach D, Wagner J, Kimmig R, Kasimir-Bauer S. Establishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment. Oncotarget. 2016 Jul 5;7(27):41677-41690. doi: 10.18632/oncotarget.9528. PubMed PMID: 27223437; PubMed Central PMCID: PMC5173087.
Aktas B, Kasimir-Bauer S, Müller V, Janni W, Fehm T, Wallwiener D, Pantel K, Tewes M. Comparison of the HER2, estrogen and progesterone receptor expression profile of primary tumor, metastases and circulating tumor cells in metastatic breast cancer patients. BMC Cancer. 2016 Jul 25;16:522. doi: 10.1186/s12885-016-2587-4. PubMed PMID: 27456970; PubMed Central PMCID: PMC4960681.
Bredemeier M, Kasimir-Bauer S, Kolberg HC, Herold T, Synoracki S, Hauch S, Edimiris P, Bankfalvi A, Tewes M, Kimmig R, Aktas B. Comparison of the PI3KCA pathway in circulating tumor cells and corresponding tumor tissue of patients with metastatic breast cancer. Mol Med Rep. 2017 May;15(5):2957-2968. doi: 10.3892/mmr.2017.6415. Epub 2017 Mar 30. PubMed PMID: 28358430; PubMed Central PMCID: PMC5428904.
Bredemeier M, Edimiris P, Mach P, Kubista M, Sjöback R, Rohlova E, Kolostova K, Hauch S, Aktas B, Tewes M, Kimmig R, Kasimir-Bauer S. Gene Expression Signatures in Circulating Tumor Cells Correlate with Response to Therapy in Metastatic Breast Cancer. Clin Chem. 2017 Oct;63(10):1585-1593. doi: 10.1373/clinchem.2016.269605. Epub 2017 Aug 3. PubMed PMID: 28778937.
Tewes M, Peis MW, Bogner S, Theysohn JM, Reinboldt MP, Schuler M, Welt A. Hepatic arterial infusion chemotherapy for extensive liver metastases of breast cancer: efficacy, safety and prognostic parameters. J Cancer Res Clin Oncol. 2017 Oct;143(10):2131-2141. doi: 10.1007/s00432-017-2462-y. Epub 2017 Jun 23. PubMed PMID: 28646261.
Tewes M, Rettler TM, Beckmann M, Scheer K, Ritterbusch U, Schuler M, Hense J. Patient-Reported-Outcome-Messung (PROM) psychosozialer Belastung und Symptome für ambulante Patienten unter kurativer oder palliative Tumortherapie – eine retrospektive Analyse eines Comprehensive Cancer Center. Der Onkologe : Organ der Deutschen Krebsgesellschaft e.V. 2018; 24(1):69-75. doi: 10.1007/s00761-017-0324-5.
Keup C, Mach P, Aktas B, Tewes M, Kolberg HC, Hauch S, Sprenger-Haussels M, Kimmig R, Kasimir-Bauer S. RNA Profiles of Circulating Tumor Cells and Extracellular Vesicles for Therapy Stratification of Metastatic Breast Cancer Patients. Clin Chem. 2018 Jul;64(7):1054-1062. doi: 10.1373/clinchem.2017.283531. Epub 2018 May 16. PubMed PMID: 29769179.
Berendt J, Thomas M, Neukirchen M, Schwartz J, Hense J, Tewes M. [Integration of Palliative Care into the Comprehensive Cancer Center of Germany - Consultation Hours and Fellowship Rotations of the Specialized Palliative Care]. Dtsch Med Wochenschr. 2018 Aug;143(17):e139-e145. doi: 10.1055/a-0626-9934. Epub 2018 Aug 22. PubMed PMID: 30134450.
Tewes M, Rettler T, Wolf N, Hense J, Schuler M, Teufel M, Beckmann M. Predictors of outpatients' request for palliative care service at a medical oncology clinic of a German comprehensive cancer center. Support Care Cancer. 2018 Oct;26(10):3641-3647. doi: 10.1007/s00520-018-4245-7. Epub 2018 May 5. PubMed PMID: 29730713.
Keup C, Storbeck M, Hauch S, Hahn P, Sprenger-Haussels M, Tewes M, Mach P, Hoffmann O, Kimmig R, Kasimir-Bauer S. Cell-Free DNA Variant Sequencing Using CTC-Depleted Blood for Comprehensive Liquid Biopsy Testing in Metastatic Breast Cancer. Cancers (Basel). 2019 Feb 18;11(2). doi: 10.3390/cancers11020238. PubMed PMID: 30781720; PubMed Central PMCID: PMC6406821.
Burmann SN, Neukirchen M, Ostgathe C, Beckmann M, Schwartz J, Scheer K, Klco-Brosius S, Hense J, Teufel M, Tewes M. Knowledge and Self-Efficacy Assessment of Residents and Fellows Following Palliative Care Unit Rotation: A Pilot Study. Am J Hosp Palliat Care. 2019 Jun;36(6):492-499. doi: 10.1177/1049909118823181. Epub 2019 Jan 8. PubMed PMID: 30621437.
Gahr S, Berendt J, Lödel S, Ostgathe C, Simon ST, Tewes M, Zader K, Schwartz J, Neukirchen M. [Palliative Care Teams in the German Comprehensive Cancer Centers]. Dtsch Med Wochenschr. 2019 Nov;144(23):e153-e159. doi: 10.1055/a-0961-7236. Epub 2019 Aug 27. PubMed PMID: 31454850.
Keup C, Benyaa K, Hauch S, Sprenger-Haussels M, Tewes M, Mach P, Bittner AK, Kimmig R, Hahn P, Kasimir-Bauer S. Targeted deep sequencing revealed variants in cell-free DNA of hormone receptor-positive metastatic breast cancer patients. Cell Mol Life Sci. 2020 Feb;77(3):497-509. doi: 10.1007/s00018-019-03189-z. Epub 2019 Jun 28. PubMed PMID: 31254045; PubMed Central PMCID: PMC7010653.
Frikkel J, Götte M, Beckmann M, Kasper S, Hense J, Teufel M, Schuler M, Tewes M. Fatigue, barriers to physical activity and predictors for motivation to exercise in advanced Cancer patients. BMC Palliat Care. 2020 Mar 31;19(1):43. doi: 10.1186/s12904-020-00542-z. PubMed PMID: 32234027; PubMed Central PMCID: PMC7110817.
Welt A, Bogner S, Arendt M, Kossow J, Huffziger A, Pohlkamp C, Steiniger H, Becker U, Alashkar F, Kohl M, Wiesweg M, Richly H, Hense J, Scheulen ME, Schuler M, Seeber S, Tewes M. Improved survival in metastatic breast cancer: results from a 20-year study involving 1033 women treated at a single comprehensive cancer center. J Cancer Res Clin Oncol. 2020 Jun;146(6):1559-1566. doi: 10.1007/s00432-020-03184-z. Epub 2020 Mar 18. PubMed PMID: 32189107; PubMed Central PMCID: PMC7230039.
Welt A, Wiesweg M, Theurer S, Abenhardt W, Groschek M, Müller L, Schröder J, Tewes M, Chiabudini M, Potthoff K, Bankfalvi A, Marschner N, Schuler M, Breitenbücher F. Buparlisib in combination with tamoxifen in pretreated patients with hormone receptor-positive, HER2-negative advanced breast cancer molecularly stratified for PIK3CA mutations and loss of PTEN expression. Cancer Med. 2020 Jul;9(13):4527-4539. doi: 10.1002/cam4.3092. Epub 2020 Apr 30. PubMed PMID: 32352244; PubMed Central PMCID: PMC7333856.
Musche V, Bäuerle A, Steinbach J, Schweda A, Hetkamp M, Weismüller B, Kohler H, Beckmann M, Herrmann K, Tewes M, Schadendorf D, Skoda EM, Teufel M. COVID-19-Related Fear and Health-Related Safety Behavior in Oncological Patients. Front Psychol. 2020;11:1984. doi: 10.3389/fpsyg.2020.01984. eCollection 2020. PubMed PMID: 32903780; PubMed Central PMCID: PMC7438892.
Bäuerle A, Musche V, Schmidt K, Schweda A, Fink M, Weismüller B, Kohler H, Herrmann K, Tewes M, Schadendorf D, Skoda EM, Teufel M. Mental Health Burden of German Cancer Patients before and after the Outbreak of COVID-19: Predictors of Mental Health Impairment. Int J Environ Res Public Health. 2021 Feb 26;18(5). doi: 10.3390/ijerph18052318. PubMed PMID: 33652949; PubMed Central PMCID: PMC7967708.
Tewes M, Baumann F, Teufel M, Ostgathe C. Symptoms During Outpatient Cancer Treatment and Options for Their Management. Dtsch Arztebl Int. 2021 Apr 30;118(17):291-7. doi: 10.3238/arztebl.m2021.0028. Review. PubMed PMID: 33531117; PubMed Central PMCID: PMC8289968.
Keup C, Suryaprakash V, Hauch S, Storbeck M, Hahn P, Sprenger-Haussels M, Kolberg HC, Tewes M, Hoffmann O, Kimmig R, Kasimir-Bauer S. Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer. Genome Med. 2021 May 17;13(1):85. doi: 10.1186/s13073-021-00902-1. PubMed PMID: 34001236; PubMed Central PMCID: PMC8130163.
Seifert R, Küper A, Tewes M, Heuschmid M, Welt A, Fendler WP, Herrmann K, Decker T. [18F]-Fluorodeoxyglucose Positron Emission Tomography/CT to Assess the Early Metabolic Response in Patients with Hormone Receptor-Positive HER2-Negative Metastasized Breast Cancer Treated with Cyclin-Dependent 4/6 Kinase Inhibitors. Oncol Res Treat. 2021;44(7-8):400-407. doi: 10.1159/000516422. Epub 2021 Jun 8. PubMed PMID: 34102639.
Frikkel J, Beckmann M, De Lazzari N, Götte M, Kasper S, Hense J, Schuler M, Teufel M, Tewes M. Changes in fatigue, barriers, and predictors towards physical activity in advanced cancer patients over a period of 12 months-a comparative study. Support Care Cancer. 2021 Sep;29(9):5127-5137. doi: 10.1007/s00520-021-06020-3. Epub 2021 Feb 19. PubMed PMID: 33608761; PubMed Central PMCID: PMC8295138.
De Lazzari N, Niels T, Tewes M, Götte M. A Systematic Review of the Safety, Feasibility and Benefits of Exercise for Patients with Advanced Cancer. Cancers (Basel). 2021 Sep 6;13(17). doi: 10.3390/cancers13174478. Review. PubMed PMID: 34503288; PubMed Central PMCID: PMC8430671.
Roch C, Heckel M, van Oorschot B, Alt-Epping B, Tewes M. Screening for Palliative Care Needs: Pilot Data From German Comprehensive Cancer Centers. JCO Oncol Pract. 2021 Oct;17(10):e1584-e1591. doi: 10.1200/OP.20.00698. Epub 2021 Feb 11. PubMed PMID: 33571007.
Berendt J, Ostgathe C, Simon ST, Tewes M, Schlieper D, Schallenburger M, Meier S, Gahr S, Schwartz J, Neukirchen M. [Cooperation between intensive care and palliative care : The status quo in German Comprehensive Cancer Centers]. Med Klin Intensivmed Notfmed. 2021 Oct;116(7):586-594. doi: 10.1007/s00063-020-00712-0. Epub 2020 Aug 7. PubMed PMID: 32767071; PubMed Central PMCID: PMC8494681.
Bäuerle A, Martus P, Erim Y, Schug C, Heinen J, Krakowczyk JB, Steinbach J, Damerau M, Bethge W, Dinkel A, Dries S, Mehnert-Theuerkauf A, Neumann A, Schadendorf D, Tewes M, Wiltink J, Wünsch A, Zipfel S, Graf J, Teufel M. Web-based mindfulness and skills-based distress reduction for patients with cancer: study protocol of the multicentre, randomised, controlled confirmatory intervention trial Reduct. BMJ Open. 2022 Jun 1;12(6):e056973. doi: 10.1136/bmjopen-2021-056973. PubMed PMID: 35649607; PubMed Central PMCID: PMC9161102.
Chwallek D, Schweda A, Neukirchen M, Hense J, Schwartz J, Mallmann B, Teufel M, Schuler M, Tewes M. [PARPACT: Paramedic Palliative Care Test : Validation of a questionnaire to assess palliative care knowledge and self-efficacy expectations of paramedics]. Schmerz. 2022 Oct;36(5):333-341. doi: 10.1007/s00482-021-00587-w. Epub 2021 Sep 29. PubMed PMID: 34586511; PubMed Central PMCID: PMC9512857.
Müller S, Fink M, Hense J, Comino MRS, Schuler M, Teufel M, Tewes M. Palliative care outpatients in a German comprehensive cancer center-identifying indicators for early and late referral. BMC Palliat Care. 2022 Dec 12;21(1):221. doi: 10.1186/s12904-022-01114-z. PubMed PMID: 36503625; PubMed Central PMCID: PMC9743520.
Fink M, Pasche S, Schmidt K, Tewes M, Schuler M, Mülley BW, Schadendorf D, Scherbaum N, Kowalski A, Skoda EM, Teufel M. Neurofeedback Treatment Affects Affective Symptoms, But Not Perceived Cognitive Impairment in Cancer Patients: Results of an Explorative Randomized Controlled Trial. Integr Cancer Ther. 2023 Jan-Dec;22:15347354221149950. doi: 10.1177/15347354221149950. PubMed PMID: 36691908; PubMed Central PMCID: PMC9893099.
Schmidt K, Krawutschke M, Kowalski A, Pasche S, Bialek A, Schweig T, Weismüller B, Tewes M, Schuler M, Hamacher R, Müller BW, Schadendorf D, Skoda EM, Teufel M, Fink M. Cancer Patients' Age-Related Benefits from Mobile Neurofeedback-Therapy in Quality of Life and Self-efficacy: A Clinical Waitlist Control Study. Appl Psychophysiol Biofeedback. 2023 Jun;48(2):217-227. doi: 10.1007/s10484-022-09571-1. Epub 2022 Nov 18. PubMed PMID: 36401150; PubMed Central PMCID: PMC9676905.
Warnecke E, Salvador Comino MR, Kocol D, Hosters B, Wiesweg M, Bauer S, Welt A, Heinzelmann A, Müller S, Schuler M, Teufel M, Tewes M. Electronic Patient-Reported Outcome Measures (ePROMs) Improve the Assessment of Underrated Physical and Psychological Symptom Burden among Oncological Inpatients. Cancers (Basel). 2023 Jun 1;15(11). doi: 10.3390/cancers15113029. PubMed PMID: 37296991; PubMed Central PMCID: PMC10252046.
Biersching T, Schweda A, Oechsle K, Nauck F, Rosenbruch J, Schuler U, Hense J, Neukirchen M, Weber M, Junghanss C, Kramer T, Ostgathe C, Thuss-Patience P, Van Oorschot B, Teufel M, Schuler M, Bausewein C, Tewes M. The OUTREACH study: oncologists of German university hospitals in rotation on a palliative care unit-evaluation of attitude and competence in palliative care and hospice. J Cancer Res Clin Oncol. 2023 Jul;149(7):2929-2936. doi: 10.1007/s00432-022-04131-w. Epub 2022 Jul 13. PubMed PMID: 35831764; PubMed Central PMCID: PMC10314826.
Braulke F, Para S, Alt-Epping B, Tewes M, Bäumer M, Haberland B, Mayer-Steinacker R, Hopprich A, de Wit M, Grabe M, Bender-Säbelkampf S, Weßling C, Aulmann C, Gerlach C, Regincos P, Fischer F, Haarmann S, Huys T, Drygas S, Rambau A, Kiani A, Schnabel A, Buhl C, Seipke S, Hiemer S, Polata S, Meßmann M, Hansmeier A, Anastasiadou L, Letsch A, Wecht D, Hellberg-Naegele M, Krug U, Wedding U, van Oorschot B. Systematic symptom screening in patients with advanced cancer treated in certified oncology centers: results of the prospective multicenter German KeSBa project. J Cancer Res Clin Oncol. 2023 Sep;149(11):8829-8842. doi: 10.1007/s00432-023-04818-8. Epub 2023 May 5. PubMed PMID: 37145199; PubMed Central PMCID: PMC10374724.
Rausch R, Bäuerle A, Rentrop V, Jansen C, Nensa F, Palm S, Tewes M, Schadendorf D, Skoda EM, Teufel M. Falling off the screening grid-Predictors for postponed utilization of psycho-oncological support in cancer patients and its implications for distress assessment and management. Psychooncology. 2023 Nov;32(11):1727-1735. doi: 10.1002/pon.6226. Epub 2023 Oct 3. PubMed PMID: 37789593.
Moukas SI, Kasimir-Bauer S, Tewes M, Kolberg HC, Hoffmann O, Kimmig R, Keup C. Ratios of monocytes and neutrophils to lymphocytes in the blood predict benefit of CDK4/6 inhibitor treatment in metastatic breast cancer. Sci Rep. 2023 Dec 2;13(1):21262. doi: 10.1038/s41598-023-47874-3. PubMed PMID: 38040730; PubMed Central PMCID: PMC10692150.
Nurtsch A, Teufel M, Jahre LM, Esber A, Rausch R, Tewes M, Schöbel C, Palm S, Schuler M, Schadendorf D, Skoda EM, Bäuerle A. Drivers and barriers of patients' acceptance of video consultation in cancer care. Digit Health. 2024 Jan-Dec;10:20552076231222108. doi: 10.1177/20552076231222108. eCollection 2024 Jan-Dec. PubMed PMID: 38188860; PubMed Central PMCID: PMC10768612.
Chwallek D, Schweda A, Neukirchen M, Risse J, Hense J, Teufel M, Tewes M. Comparison of Palliative Knowledge and Self-Efficacy Expectation of German Paramedics Between a Rural and an Urban Structured Emergency Medical Service Area. J Palliat Care. 2024 Feb 19;:8258597231221916. doi: 10.1177/08258597231221916. [Epub ahead of print] PubMed PMID: 38374646.
Berendt J, Brunner S, Heckel M, Tewes M, Ostgathe C, Gahr S. Symptom burden and relief in palliative care units of German Comprehensive Cancer Center and other hospitals. J Cancer Res Clin Oncol. 2024 Mar 27;150(3):160. doi: 10.1007/s00432-023-05557-6. PubMed PMID: 38532121; PubMed Central PMCID: PMC10965705.
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