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Wlodawer A. Protein crystallography: alive and well. FEBS J. 2021 Oct;288(20):5786-5787. doi: 10.1111/febs.15822. Epub 2021 Mar 24. PubMed PMID: 33759375.
Rosati M, Agarwal M, Hu X, Devasundaram S, Stellas D, Chowdhury B, Bear J, Burns R, Donohue D, Pessaint L, Andersen H, Lewis MG, Terpos E, Dimopoulos MA, Wlodawer A, Mullins JI, Venzon DJ, Pavlakis GN, Felber BK. Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques. PLoS Pathog. 2021 Sep;17(9):e1009701. doi: 10.1371/journal.ppat.1009701. eCollection 2021 Sep. PubMed PMID: 34551020; PubMed Central PMCID: PMC8489704.
Li M, Srp J, Mareš M, Wlodawer A, Gustchina A. Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI. Acta Crystallogr D Struct Biol. 2021 Aug 1;77(Pt 8):1084-1098. doi: 10.1107/S2059798321006483. Epub 2021 Jul 29. PubMed PMID: 34342281; PubMed Central PMCID: PMC8329858.
Lubkowski J, Wlodawer A. Structural and biochemical properties of L-asparaginase. FEBS J. 2021 Jul;288(14):4183-4209. doi: 10.1111/febs.16042. Epub 2021 Jun 19. Review. PubMed PMID: 34060231.
Grabowski M, Macnar JM, Cymborowski M, Cooper DR, Shabalin IG, Gilski M, Brzezinski D, Kowiel M, Dauter Z, Rupp B, Wlodawer A, Jaskolski M, Minor W. Rapid response to emerging biomedical challenges and threats. IUCrJ. 2021 May 1;8(Pt 3):395-407. doi: 10.1107/S2052252521003018. eCollection 2021 May 1. PubMed PMID: 33953926; PubMed Central PMCID: PMC8086160.
Jaskolski M, Dauter Z, Shabalin IG, Gilski M, Brzezinski D, Kowiel M, Rupp B, Wlodawer A. Crystallographic models of SARS-CoV-2 3CLpro: in-depth assessment of structure quality and validation. IUCrJ. 2021 Mar 1;8(Pt 2):238-256. doi: 10.1107/S2052252521001159. eCollection 2021 Mar 1. PubMed PMID: 33708401; PubMed Central PMCID: PMC7924243.
Hattori SI, Higashi-Kuwata N, Hayashi H, Allu SR, Raghavaiah J, Bulut H, Das D, Anson BJ, Lendy EK, Takamatsu Y, Takamune N, Kishimoto N, Murayama K, Hasegawa K, Li M, Davis DA, Kodama EN, Yarchoan R, Wlodawer A, Misumi S, Mesecar AD, Ghosh AK, Mitsuya H. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nat Commun. 2021 Jan 28;12(1):668. doi: 10.1038/s41467-021-20900-6. PubMed PMID: 33510133; PubMed Central PMCID: PMC7843602.
Jaskolski M, Wlodawer A, Dauter Z, Shabalin I, Chruszcz M. Celebrating the 75th birthday of Professor Wladek Minor, one of the most accomplished Polish-American structural biologists. Acta Biochim Pol. 2021 Jan 21;68(1):1-4. doi: 10.18388/abp.2020_5539. PubMed PMID: 33476109.
Rathore I, Mishra V, Patel C, Xiao H, Gustchina A, Wlodawer A, Yada RY, Bhaumik P. Activation mechanism of plasmepsins, pepsin-like aspartic proteases from Plasmodium, follows a unique trans-activation pathway. FEBS J. 2021 Jan;288(2):678-698. doi: 10.1111/febs.15363. Epub 2020 May 26. PubMed PMID: 32385863.
Brzezinski D, Kowiel M, Cooper DR, Cymborowski M, Grabowski M, Wlodawer A, Dauter Z, Shabalin IG, Gilski M, Rupp B, Jaskolski M, Minor W. Covid-19.bioreproducibility.org: A web resource for SARS-CoV-2-related structural models. Protein Sci. 2021 Jan;30(1):115-124. doi: 10.1002/pro.3959. Epub 2020 Oct 8. PubMed PMID: 32981130; PubMed Central PMCID: PMC7537053.
Beyer H, Virtanen S, Aranko A, Mikula K, Lountos G, Wlodawer A, Ollila O, Iwaï H. The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms. Int J Mol Sci. 2020 November; 21(21). doi: 10.3390/ijms21218367.
Strzelczyk P, Zhang D, Dyba M, Wlodawer A, Lubkowski J. Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria. Sci Rep. 2020 Oct 15;10(1):17516. doi: 10.1038/s41598-020-74480-4. PubMed PMID: 33060684; PubMed Central PMCID: PMC7567106.
Andrianova AG, Kudzhaev AM, Abrikosova VA, Gustchina AE, Smirnov IV, Rotanova TV. Involvement of the N Domain Residues E34, K35, and R38 in the Functionally Active Structure of Escherichia coli Lon Protease. Acta Naturae. 2020 Oct-Dec;12(4):86-97. doi: 10.32607/actanaturae.11197. PubMed PMID: 33456980; PubMed Central PMCID: PMC7800598.
Wlodawer A, Dauter Z, Shabalin IG, Gilski M, Brzezinski D, Kowiel M, Minor W, Rupp B, Jaskolski M. Ligand-centered assessment of SARS-CoV-2 drug target models in the Protein Data Bank. FEBS J. 2020 Sep;287(17):3703-3718. doi: 10.1111/febs.15366. Epub 2020 Jun 24. PubMed PMID: 32418327; PubMed Central PMCID: PMC7276724.
Lubkowski J, Vanegas J, Chan WK, Lorenzi PL, Weinstein JN, Sukharev S, Fushman D, Rempe S, Anishkin A, Wlodawer A. Mechanism of Catalysis by l-Asparaginase. Biochemistry. 2020 May 26;59(20):1927-1945. doi: 10.1021/acs.biochem.0c00116. Epub 2020 May 11. PubMed PMID: 32364696.
Beyer HM, Mikula KM, Li M, Wlodawer A, Iwaï H. The crystal structure of the naturally split gp41-1 intein guides the engineering of orthogonal split inteins from cis-splicing inteins. FEBS J. 2020 May;287(9):1886-1898. doi: 10.1111/febs.15113. Epub 2019 Nov 19. PubMed PMID: 31665813; PubMed Central PMCID: PMC7190452.
Botos I, Lountos GT, Wu W, Cherry S, Ghirlando R, Kudzhaev AM, Rotanova TV, de Val N, Tropea JE, Gustchina A, Wlodawer A. Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery. Current Research in Structural Biology. 2019 November; 1:13-20. doi: 10.1016/j.crstbi.2019.10.001.
Lubkowski J, Wlodawer A. Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase. Protein Sci. 2019 Oct;28(10):1850-1864. doi: 10.1002/pro.3709. Epub 2019 Aug 29. PubMed PMID: 31423681; PubMed Central PMCID: PMC6740147.
Rotanova TV, Andrianova AG, Kudzhaev AM, Li M, Botos I, Wlodawer A, Gustchina A. New insights into structural and functional relationships between LonA proteases and ClpB chaperones. FEBS Open Bio. 2019 Sep;9(9):1536-1551. doi: 10.1002/2211-5463.12691. Epub 2019 Jul 21. PubMed PMID: 31237118; PubMed Central PMCID: PMC6722904.
Lubkowski J, Chan W, Wlodawer A. Opportunistic complexes of E. coli L-asparaginases with citrate anions. Sci Rep. 2019 Jul 30;9(1):11070. doi: 10.1038/s41598-019-46432-0. PubMed PMID: 31363102; PubMed Central PMCID: PMC6667453.
Li M, Srp J, Gustchina A, Dauter Z, Mares M, Wlodawer A. Crystal structures of the complex of a kallikrein inhibitor from Bauhinia bauhinioides with trypsin and modeling of kallikrein complexes. Acta Crystallogr D Struct Biol. 2019 Jan 1;75(Pt 1):56-69. doi: 10.1107/S2059798318016492. Epub 2019 Jan 7. PubMed PMID: 30644845; PubMed Central PMCID: PMC6333282.
Wlodawer A, Li M, Gustchina A, Dauter Z, Uchida K, Oyama H, Goldfarb NE, Dunn BM, Oda K. Correction to "Inhibitor Complexes of the Pseudomonas Serine-Carboxyl Proteinase". Biochemistry. 2018 Nov 13;. doi: 10.1021/acs.biochem.8b01130. [Epub ahead of print] PubMed PMID: 30421926.
Lubkowski J, Sonmez C, Smirnov SV, Anishkin A, Kotenko SV, Wlodawer A. Crystal Structure of the Labile Complex of IL-24 with the Extracellular Domains of IL-22R1 and IL-20R2. J Immunol. 2018 Oct 1;201(7):2082-2093. doi: 10.4049/jimmunol.1800726. Epub 2018 Aug 15. PubMed PMID: 30111632; PubMed Central PMCID: PMC6143405.
Dauter Z, Wlodawer A. Crystallographically correct but confusing presentation of structural models deposited in the Protein Data Bank. Acta Crystallogr D Struct Biol. 2018 Sep 1;74(Pt 9):939-945. doi: 10.1107/S2059798318009828. Epub 2018 Sep 5. PubMed PMID: 30198902; PubMed Central PMCID: PMC6130463.
Wlodawer A, Dauter Z. Do structures matter any more?. FEBS J. 2018 Sep;285(18):3322-3323. doi: 10.1111/febs.14630. PubMed PMID: 30221844.
Raczynska JE, Shabalin IG, Minor W, Wlodawer A, Jaskolski M. A close look onto structural models and primary ligands of metallo-β-lactamases. Drug Resist Updat. 2018 Sep;40:1-12. doi: 10.1016/j.drup.2018.08.001. Epub 2018 Aug 25. Review. PubMed PMID: 30466711; PubMed Central PMCID: PMC6260963.
Mishra V, Rathore I, Arekar A, Sthanam LK, Xiao H, Kiso Y, Sen S, Patankar S, Gustchina A, Hidaka K, Wlodawer A, Yada RY, Bhaumik P. Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins - biochemical and structural insights. FEBS J. 2018 Aug;285(16):3077-3096. doi: 10.1111/febs.14598. Epub 2018 Jul 7. PubMed PMID: 29943906; PubMed Central PMCID: PMC6309945.
Dauter Z, Wlodawer A. Unexpected Specificity of a Trypsin-like Enzyme. Structure. 2018 Apr 3;26(4):530-531. doi: 10.1016/j.str.2018.03.007. PubMed PMID: 29617650.
Wlodawer A, Dauter Z, Porebski PJ, Minor W, Stanfield R, Jaskolski M, Pozharski E, Weichenberger CX, Rupp B. Detect, correct, retract: How to manage incorrect structural models. FEBS J. 2018 Feb;285(3):444-466. doi: 10.1111/febs.14320. Epub 2017 Nov 27. Review. PubMed PMID: 29113027; PubMed Central PMCID: PMC5799025.
Iwaï H, Mikula KM, Oeemig JS, Zhou D, Li M, Wlodawer A. Structural Basis for the Persistence of Homing Endonucleases in Transcription Factor IIB Inteins. J Mol Biol. 2017 Dec 8;429(24):3942-3956. doi: 10.1016/j.jmb.2017.10.016. Epub 2017 Oct 18. PubMed PMID: 29055778; PubMed Central PMCID: PMC6309676.
Wlodawer A. Online tools for enhancing presentation, understanding, and retention of 3D structural data. FEBS J. 2017 Dec;284(23):3974-3976. doi: 10.1111/febs.14316. PubMed PMID: 29205914; PubMed Central PMCID: PMC6293472.
Wlodawer A, Li M, Dauter Z. High-Resolution Cryo-EM Maps and Models: A Crystallographer's Perspective. Structure. 2017 Oct 3;25(10):1589-1597.e1. doi: 10.1016/j.str.2017.07.012. Epub 2017 Aug 31. PubMed PMID: 28867613; PubMed Central PMCID: PMC5657611.
Jha JK, Li M, Ghirlando R, Miller Jenkins LM, Wlodawer A, Chattoraj D. The DnaK Chaperone Uses Different Mechanisms To Promote and Inhibit Replication of Vibrio cholerae Chromosome 2. mBio. 2017 Apr 18;8(2). doi: 10.1128/mBio.00427-17. PubMed PMID: 28420739; PubMed Central PMCID: PMC5395669.
Ottaiano TF, Andrade SS, de Oliveira C, Silva MCC, Buri MV, Juliano MA, Girão MJBC, Sampaio MU, Schmaier AH, Wlodawer A, Maffei FHA, Oliva MLV. Plasma kallikrein enhances platelet aggregation response by subthreshold doses of ADP. Biochimie. 2017 Apr;135:72-81. doi: 10.1016/j.biochi.2017.01.010. Epub 2017 Jan 20. PubMed PMID: 28115185; PubMed Central PMCID: PMC5346445.
Wlodawer A, Dauter Z. `Atomic resolution': a badly abused term in structural biology. Acta Crystallogr D Struct Biol. 2017 Apr 1;73(Pt 4):379-380. doi: 10.1107/S205979831700225X. Epub 2017 Mar 31. PubMed PMID: 28375149; PubMed Central PMCID: PMC5379937.
Lubkowski J, Durbin SV, Silva MC, Farnsworth D, Gildersleeve JC, Oliva ML, Wlodawer A. Structural analysis and unique molecular recognition properties of a Bauhinia forficata lectin that inhibits cancer cell growth. FEBS J. 2017 Feb;284(3):429-450. doi: 10.1111/febs.13989. Epub 2017 Feb 1. PubMed PMID: 27973758; PubMed Central PMCID: PMC6257985.
Wlodawer A. Stereochemistry and Validation of Macromolecular Structures. Methods Mol Biol. 2017;1607:595-610. doi: 10.1007/978-1-4939-7000-1_24. Review. PubMed PMID: 28573590; PubMed Central PMCID: PMC5560084.
Rupp B, Wlodawer A, Minor W, Helliwell JR, Jaskolski M. Correcting the record of structural publications requires joint effort of the community and journal editors. FEBS J. 2016 Dec;283(24):4452-4457. doi: 10.1111/febs.13765. Epub 2016 Jun 10. PubMed PMID: 27229767; PubMed Central PMCID: PMC5124416.
Zhang D, Wlodawer A, Lubkowski J. Crystal Structure of a Complex of the Intracellular Domain of Interferon λ Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1. J Mol Biol. 2016 Nov 20;428(23):4651-4668. doi: 10.1016/j.jmb.2016.10.005. Epub 2016 Oct 7. PubMed PMID: 27725180; PubMed Central PMCID: PMC6288811.
Raczynska JE, Wlodawer A, Jaskolski M. Prior knowledge or freedom of interpretation? A critical look at a recently published classification of "novel" Zn binding sites. Proteins. 2016 Jun;84(6):770-6. doi: 10.1002/prot.25024. Epub 2016 Mar 10. PubMed PMID: 26914344; PubMed Central PMCID: PMC4870113.
Li M, Kandror O, Akopian T, Dharkar P, Wlodawer A, Maurizi MR, Goldberg AL. Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis. J Biol Chem. 2016 Apr 1;291(14):7465-76. doi: 10.1074/jbc.M115.700344. Epub 2016 Feb 8. PubMed PMID: 26858247; PubMed Central PMCID: PMC4817177.
Leal AR, Cruz R, Bur D, Huesgen PF, Faro R, Manadas B, Wlodawer A, Faro C, Simões I. Enzymatic properties, evidence for in vivo expression, and intracellular localization of shewasin D, the pepsin homolog from Shewanella denitrificans. Sci Rep. 2016 Mar 31;6:23869. doi: 10.1038/srep23869. PubMed PMID: 27029611; PubMed Central PMCID: PMC4814920.
Wlodawer A. Introducing Structural Snapshots. The FEBS journal. 2016 March; 283(5):815. doi: 10.1111/febs.13583.
Minor W, Dauter Z, Helliwell JR, Jaskolski M, Wlodawer A. Safeguarding Structural Data Repositories against Bad Apples. Structure. 2016 Feb 2;24(2):216-20. doi: 10.1016/j.str.2015.12.010. Review. PubMed PMID: 26840827; PubMed Central PMCID: PMC4743038.
Woodfolk JA, Glesner J, Wright PW, Kepley CL, Li M, Himly M, Muehling LM, Gustchina A, Wlodawer A, Chapman MD, Pomés A. Antigenic Determinants of the Bilobal Cockroach Allergen Bla g 2. J Biol Chem. 2016 Jan 29;291(5):2288-301. doi: 10.1074/jbc.M115.702324. Epub 2015 Dec 7. PubMed PMID: 26644466; PubMed Central PMCID: PMC4732212.
Wlodawer A, Jaskólski M. Inhibitors of HIV protease. In: Bradshaw RA, Stahl PD, editors. Encyclopedia of Cell Biology (Volume 1) Waltham, MA: Academic Press; 2016. p.738-745.
Dauter Z, Wlodawer A. Progress in protein crystallography. Protein Pept Lett. 2016;23(3):201-10. doi: 10.2174/0929866523666160106153524. PubMed PMID: 26732246; PubMed Central PMCID: PMC6287266.
Wlodawer A. Serendipity, politics, and crystal structures, or how I became a protein crystallographer. Postepy Biochem. 2016;62(3):239-241. PubMed PMID: 28132476; PubMed Central PMCID: PMC6292444.
Nunes NN, Ferreira RS, Silva-Lucca RA, de Sá LF, de Oliveira AE, Correia MT, Paiva PM, Wlodawer A, Oliva ML. Potential of the Lectin/Inhibitor Isolated from Crataeva tapia Bark (CrataBL) for Controlling Callosobruchus maculatus Larva Development. J Agric Food Chem. 2015 Dec 9;63(48):10431-6. doi: 10.1021/acs.jafc.5b03634. Epub 2015 Dec 1. PubMed PMID: 26568149; PubMed Central PMCID: PMC6290478.
Jaskolski M, Miller M, Mohana Rao JK, Gustchina A, Wlodawer A. Elucidation of the structure of retroviral proteases: a reminiscence. FEBS J. 2015 Nov;282(21):4059-66. doi: 10.1111/febs.13397. Epub 2015 Aug 28. PubMed PMID: 26258480; PubMed Central PMCID: PMC6310002.
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