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  1. Lapierre LA, Kumar R, Hales CM, Navarre J, Bhartur SG, Burnette JO, Provance DW Jr, Mercer JA, Bähler M, Goldenring JR. Myosin vb is associated with plasma membrane recycling systems. Mol Biol Cell. 2001 Jun;12(6):1843-57. doi: 10.1091/mbc.12.6.1843. PubMed PMID: 11408590; PubMed Central PMCID: PMC37346.
  2. Jones KW, Gorzynski K, Hales CM, Fischer U, Badbanchi F, Terns RM, Terns MP. Direct interaction of the spinal muscular atrophy disease protein SMN with the small nucleolar RNA-associated protein fibrillarin. J Biol Chem. 2001 Oct 19;276(42):38645-51. doi: 10.1074/jbc.M106161200. Epub 2001 Aug 16. PubMed PMID: 11509571.
  3. Hales CM, Griner R, Hobdy-Henderson KC, Dorn MC, Hardy D, Kumar R, Navarre J, Chan EK, Lapierre LA, Goldenring JR. Identification and characterization of a family of Rab11-interacting proteins. J Biol Chem. 2001 Oct 19;276(42):39067-75. doi: 10.1074/jbc.M104831200. Epub 2001 Aug 8. PubMed PMID: 11495908.
  4. Hales CM, Vaerman JP, Goldenring JR. Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling. J Biol Chem. 2002 Dec 27;277(52):50415-21. doi: 10.1074/jbc.M209270200. Epub 2002 Oct 21. PubMed PMID: 12393859.
  5. Hobdy-Henderson KC, Hales CM, Lapierre LA, Cheney RE, Goldenring JR. Dynamics of the apical plasma membrane recycling system during cell division. Traffic. 2003 Oct;4(10):681-93. PubMed PMID: 12956871.
  6. Ducharme NA, Hales CM, Lapierre LA, Ham AJ, Oztan A, Apodaca G, Goldenring JR. MARK2/EMK1/Par-1Balpha phosphorylation of Rab11-family interacting protein 2 is necessary for the timely establishment of polarity in Madin-Darby canine kidney cells. Mol Biol Cell. 2006 Aug;17(8):3625-37. doi: 10.1091/mbc.e05-08-0736. Epub 2006 Jun 14. PubMed PMID: 16775013; PubMed Central PMCID: PMC1525241.
  7. Hales CM, Rolston JD, Potter SM. How to culture, record and stimulate neuronal networks on micro-electrode arrays (MEAs). J Vis Exp. 2010 May 30;(39). doi: 10.3791/2056. PubMed PMID: 20517199; PubMed Central PMCID: PMC3152853.
  8. Hales CM, Zeller-Townson R, Newman JP, Shoemaker JT, Killian NJ, Potter SM. Stimulus-evoked high frequency oscillations are present in neuronal networks on microelectrode arrays. Front Neural Circuits. 2012;6:29. doi: 10.3389/fncir.2012.00029. eCollection 2012. PubMed PMID: 22615686; PubMed Central PMCID: PMC3351760.
  9. Hales CM, Hu WT. From frontotemporal lobar degeneration pathology to frontotemporal lobar degeneration biomarkers. Int Rev Psychiatry. 2013 Apr;25(2):210-20. doi: 10.3109/09540261.2013.776522. Review. PubMed PMID: 23611350.
  10. Xu Z, Poidevin M, Li X, Li Y, Shu L, Nelson DL, Li H, Hales CM, Gearing M, Wingo TS, Jin P. Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7778-83. doi: 10.1073/pnas.1219643110. Epub 2013 Apr 3. PubMed PMID: 23553836; PubMed Central PMCID: PMC3651485.
  11. Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, Diner I, Heilman CJ, Rees HD, Wu H, Lin L, Szulwach KE, Gearing M, Mufson EJ, Bennett DA, Montine TJ, Seyfried NT, Wingo TS, Sun YE, Jin P, Hanfelt J, Willcock DM, Levey A, Lah JJ, Peng J. U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16562-7. doi: 10.1073/pnas.1310249110. Epub 2013 Sep 10. PubMed PMID: 24023061; PubMed Central PMCID: PMC3799305.
  12. Hales CM, Rees H, Seyfried NT, Dammer EB, Duong DM, Gearing M, Montine TJ, Troncoso JC, Thambisetty M, Levey AI, Lah JJ, Wingo TS. Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes. J Neuropathol Exp Neurol. 2013 Nov;72(11):1009-15. doi: 10.1097/01.jnen.0000435847.59828.db. PubMed PMID: 24128675; PubMed Central PMCID: PMC4037931.
  13. Hu WT, Watts K, Grossman M, Glass J, Lah JJ, Hales C, Shelnutt M, Van Deerlin V, Trojanowski JQ, Levey AI. Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP. Neurology. 2013 Nov 26;81(22):1945-52. doi: 10.1212/01.wnl.0000436625.63650.27. Epub 2013 Oct 30. PubMed PMID: 24174584; PubMed Central PMCID: PMC3843382.
  14. Herskowitz JH, Feng Y, Mattheyses AL, Hales CM, Higginbotham LA, Duong DM, Montine TJ, Troncoso JC, Thambisetty M, Seyfried NT, Levey AI, Lah JJ. Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model. J Neurosci. 2013 Dec 4;33(49):19086-98. doi: 10.1523/JNEUROSCI.2508-13.2013. PubMed PMID: 24305806; PubMed Central PMCID: PMC3850036.
  15. Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. PubMed PMID: 24450891; PubMed Central PMCID: PMC4159618.
  16. Hales CM, Seyfried NT, Dammer EB, Duong D, Yi H, Gearing M, Troncoso JC, Mufson EJ, Thambisetty M, Levey AI, Lah JJ. U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21. Mol Neurodegener. 2014 Apr 28;9:15. doi: 10.1186/1750-1326-9-15. PubMed PMID: 24773620; PubMed Central PMCID: PMC4022210.
  17. Lin L, Hales CM, Garber K, Jin P. Fat mass and obesity-associated (FTO) protein interacts with CaMKII and modulates the activity of CREB signaling pathway. Hum Mol Genet. 2014 Jun 15;23(12):3299-306. doi: 10.1093/hmg/ddu043. Epub 2014 Jan 31. PubMed PMID: 24488767; PubMed Central PMCID: PMC4030783.
  18. Hales CM, Dammer EB, Diner I, Yi H, Seyfried NT, Gearing M, Glass JD, Montine TJ, Levey AI, Lah JJ. Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease. Brain Pathol. 2014 Jul;24(4):344-51. doi: 10.1111/bpa.12133. Epub 2014 Apr 14. PubMed PMID: 24571648; PubMed Central PMCID: PMC4096308.
  19. Bai B, Chen PC, Hales CM, Wu Z, Pagala V, High AA, Levey AI, Lah JJ, Peng J. Integrated approaches for analyzing U1-70K cleavage in Alzheimer's disease. J Proteome Res. 2014 Nov 7;13(11):4526-34. doi: 10.1021/pr5003593. Epub 2014 Jun 13. PubMed PMID: 24902715; PubMed Central PMCID: PMC4227550.
  20. Hales C, Neill S, Gearing M, Cooper D, Glass J, Lah J. Late-stage CTE pathology in a retired soccer player with dementia. Neurology. 2014 Dec 9;83(24):2307-9. doi: 10.1212/WNL.0000000000001081. Epub 2014 Nov 5. PubMed PMID: 25378682; PubMed Central PMCID: PMC4277667.
  21. Diner I, Hales CM, Bishof I, Rabenold L, Duong DM, Yi H, Laur O, Gearing M, Troncoso J, Thambisetty M, Lah JJ, Levey AI, Seyfried NT. Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease. J Biol Chem. 2014 Dec 19;289(51):35296-313. doi: 10.1074/jbc.M114.562959. Epub 2014 Oct 29. PubMed PMID: 25355317; PubMed Central PMCID: PMC4271217.
  22. Hu WT, Watts KD, Tailor P, Nguyen TP, Howell JC, Lee RC, Seyfried NT, Gearing M, Hales CM, Levey AI, Lah JJ, Lee EK. CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease. Acta Neuropathol Commun. 2016 Feb 17;4:14. doi: 10.1186/s40478-016-0277-8. PubMed PMID: 26887322; PubMed Central PMCID: PMC4758165.
  23. Holler CJ, Taylor G, McEachin ZT, Deng Q, Watkins WJ, Hudson K, Easley CA, Hu WT, Hales CM, Rossoll W, Bassell GJ, Kukar T. Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia. Mol Neurodegener. 2016 Jun 24;11(1):46. doi: 10.1186/s13024-016-0114-3. PubMed PMID: 27341800; PubMed Central PMCID: PMC4919863.
  24. Preininger MK, Jha R, Maxwell JT, Wu Q, Singh M, Wang B, Dalal A, Mceachin ZT, Rossoll W, Hales CM, Fischbach PS, Wagner MB, Xu C. A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses. Dis Model Mech. 2016 Sep 1;9(9):927-39. doi: 10.1242/dmm.026823. Epub 2016 Aug 4. PubMed PMID: 27491078; PubMed Central PMCID: PMC5047684.
  25. Hales CM, Dammer EB, Deng Q, Duong DM, Gearing M, Troncoso JC, Thambisetty M, Lah JJ, Shulman JM, Levey AI, Seyfried NT. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. 2016 Dec;16(23):3042-3053. doi: 10.1002/pmic.201600057. PubMed PMID: 27718298; PubMed Central PMCID: PMC5462625.
  26. Seyfried NT, Dammer EB, Swarup V, Nandakumar D, Duong DM, Yin L, Deng Q, Nguyen T, Hales CM, Wingo T, Glass J, Gearing M, Thambisetty M, Troncoso JC, Geschwind DH, Lah JJ, Levey AI. A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease. Cell Syst. 2017 Jan 25;4(1):60-72.e4. doi: 10.1016/j.cels.2016.11.006. Epub 2016 Dec 15. PubMed PMID: 27989508; PubMed Central PMCID: PMC5269514.
  27. Konrad C, Kawamata H, Bredvik KG, Arreguin AJ, Cajamarca SA, Hupf JC, Ravits JM, Miller TM, Maragakis NJ, Hales CM, Glass JD, Gross S, Mitsumoto H, Manfredi G. Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients. Mol Neurodegener. 2017 Oct 24;12(1):76. doi: 10.1186/s13024-017-0217-5. PubMed PMID: 29065921; PubMed Central PMCID: PMC5655870.
  28. Cherry JD, Zeineddin A, Dammer EB, Webster JA, Duong D, Seyfried NT, Levey AI, Alvarez VE, Huber BR, Stein TD, Kiernan PT, McKee AC, Lah JJ, Hales CM. Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy. J Neuropathol Exp Neurol. 2018 Jan 1;77(1):40-49. doi: 10.1093/jnen/nlx100. PubMed PMID: 29145658; PubMed Central PMCID: PMC5939631.
  29. Chou CC, Zhang Y, Umoh ME, Vaughan SW, Lorenzini I, Liu F, Sayegh M, Donlin-Asp PG, Chen YH, Duong DM, Seyfried NT, Powers MA, Kukar T, Hales CM, Gearing M, Cairns NJ, Boylan KB, Dickson DW, Rademakers R, Zhang YJ, Petrucelli L, Sattler R, Zarnescu DC, Glass JD, Rossoll W. TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD. Nat Neurosci. 2018 Feb;21(2):228-239. doi: 10.1038/s41593-017-0047-3. Epub 2018 Jan 8. PubMed PMID: 29311743; PubMed Central PMCID: PMC5800968.
  30. Rangaraju S, Dammer EB, Raza SA, Gao T, Xiao H, Betarbet R, Duong DM, Webster JA, Hales CM, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins. Mol Neurodegener. 2018 Jun 28;13(1):34. doi: 10.1186/s13024-018-0266-4. PubMed PMID: 29954413; PubMed Central PMCID: PMC6025801.
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