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A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations.

Fan W, Waymire KG, Narula N, Li P, Rocher C, Coskun PE, Vannan MA, Narula J, Macgregor GR, Wallace DC.

Science. 2008 Feb 15;319(5865):958-62. doi: 10.1126/science.1147786.

PMID: 18276892 [PubMed - indexed for MEDLINE]

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