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csrnp1b cysteine-serine-rich nuclear protein 1b [ Danio rerio (zebrafish) ]

Gene ID: 322795, updated on 27-Mar-2024

Summary

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Official Symbol
csrnp1bprovided by ZNC
Official Full Name
cysteine-serine-rich nuclear protein 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1515
See related
Ensembl:ENSDARG00000038429 AllianceGenome:ZFIN:ZDB-GENE-030131-1515
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb73e11; zgc:66340; wu:fb73e11
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within diencephalon development and midbrain development. Predicted to be active in nucleus. Is expressed in several structures, including anterior neural rod; axial mesoderm; axis; nervous system; and trunk. Orthologous to human CSRNP1 (cysteine and serine rich nuclear protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See csrnp1b in Genome Data Viewer
Location:
chromosome: 24
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (19705481..19719251, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (19561062..19574840, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene sulfatase 1 Neighboring gene solute carrier organic anion transporter family member 5A1 Neighboring gene LIM domain-containing protein Neighboring gene solute carrier family 22 member 13b Neighboring gene solute carrier family 22 member 13-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Genome-wide analysis of Tol2 transposon reintegration in zebrafish. Kondrychyn I, et al. BMC Genomics, 2009 Sep 8. PMID 19737393, Free PMC Article
  2. In vivo analysis of choroid plexus morphogenesis in zebrafish. García-Lecea M, et al. PLoS One, 2008 Sep 1. PMID 18769618, Free PMC Article
  3. Cystein-serine-rich nuclear protein 1, Axud1/Csrnp1, is essential for cephalic neural progenitor proliferation and survival in zebrafish. Feijóo CG, et al. Dev Dyn, 2009 Aug. PMID 19544579
  4. csrnp1a is necessary for the development of primitive hematopoiesis progenitors in zebrafish. Espina J, et al. PLoS One, 2013. PMID 23326522, Free PMC Article
  5. Trapping cardiac recessive mutants via expression-based insertional mutagenesis screening. Ding Y, et al. Circ Res, 2013 Feb 15. PMID 23283723, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within diencephalon development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within midbrain development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cysteine/serine-rich nuclear protein 1; cysteine/serine-rich nuclear protein 1b
Names
DrAXUD1
axud1
csrnp1l
csrnpl

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199619.1 → NP_955913.1  cysteine/serine-rich nuclear protein 1b

    See identical proteins and their annotated locations for NP_955913.1

    Status: PROVISIONAL

    Source sequence(s)
    BC057518
    UniProtKB/TrEMBL
    Q6PFK3
    Related
    ENSDARP00000056081.3, ENSDART00000056082.5
    Conserved Domains (1) summary
    pfam16019
    Location:74 → 289
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    19705481..19719251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005162674.4 → XP_005162731.1  cysteine/serine-rich nuclear protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B9M0, E9QH67
    Related
    ENSDARP00000098740.3, ENSDART00000109107.5
    Conserved Domains (1) summary
    pfam16019
    Location:74 → 289
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
Nucleotide Protein Strain
Heading Accession and Version

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