Similar articles for PMID: 31663025

Year	Number of Results
2001	2
2003	1
2006	2
2007	1
2010	1
2011	2
2012	3
2013	2
2014	5
2015	10
2016	19
2017	15
2018	19
2019	13
2020	4
2021	3
2022	1
2024	0

1

Bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation.

Delivoria DC, Chia S, Habchi J, Perni M, Matis I, Papaevgeniou N, Reczko M, Chondrogianni N, Dobson CM, Vendruscolo M, Skretas G. Delivoria DC, et al. Sci Adv. 2019 Oct 16;5(10):eaax5108. doi: 10.1126/sciadv.aax5108. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31663025 Free PMC article.

2

An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer's disease.

Habchi J, Arosio P, Perni M, Costa AR, Yagi-Utsumi M, Joshi P, Chia S, Cohen SI, Müller MB, Linse S, Nollen EA, Dobson CM, Knowles TP, Vendruscolo M. Habchi J, et al. Sci Adv. 2016 Feb 12;2(2):e1501244. doi: 10.1126/sciadv.1501244. eCollection 2016 Feb. Sci Adv. 2016. PMID: 26933687 Free PMC article.

3

A Fragment-Based Method of Creating Small-Molecule Libraries to Target the Aggregation of Intrinsically Disordered Proteins.

Joshi P, Chia S, Habchi J, Knowles TP, Dobson CM, Vendruscolo M. Joshi P, et al. ACS Comb Sci. 2016 Mar 14;18(3):144-53. doi: 10.1021/acscombsci.5b00129. Epub 2016 Feb 29. ACS Comb Sci. 2016. PMID: 26923286

4

Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease.

Habchi J, Chia S, Limbocker R, Mannini B, Ahn M, Perni M, Hansson O, Arosio P, Kumita JR, Challa PK, Cohen SI, Linse S, Dobson CM, Knowles TP, Vendruscolo M. Habchi J, et al. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E200-E208. doi: 10.1073/pnas.1615613114. Epub 2016 Dec 23. Proc Natl Acad Sci U S A. 2017. PMID: 28011763 Free PMC article.

5

A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer's disease.

Ikenoue T, Aprile FA, Sormanni P, Ruggeri FS, Perni M, Heller GT, Haas CP, Middel C, Limbocker R, Mannini B, Michaels TCT, Knowles TPJ, Dobson CM, Vendruscolo M. Ikenoue T, et al. Sci Rep. 2020 Sep 17;10(1):15280. doi: 10.1038/s41598-020-69626-3. Sci Rep. 2020. PMID: 32943652 Free PMC article.

6

Insights into the Molecular Mechanisms of Alzheimer's and Parkinson's Diseases with Molecular Simulations: Understanding the Roles of Artificial and Pathological Missense Mutations in Intrinsically Disordered Proteins Related to Pathology.

Coskuner-Weber O, Uversky VN. Coskuner-Weber O, et al. Int J Mol Sci. 2018 Jan 24;19(2):336. doi: 10.3390/ijms19020336. Int J Mol Sci. 2018. PMID: 29364151 Free PMC article. Review.

7

Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method.

Aprile FA, Sormanni P, Perni M, Arosio P, Linse S, Knowles TPJ, Dobson CM, Vendruscolo M. Aprile FA, et al. Sci Adv. 2017 Jun 21;3(6):e1700488. doi: 10.1126/sciadv.1700488. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28691099 Free PMC article.

8

A plant cell-based system that predicts aβ42 misfolding: potential as a drug discovery tool for Alzheimer's disease.

Zhao T, Zeng Y, Kermode AR. Zhao T, et al. Mol Genet Metab. 2012 Nov;107(3):571-9. doi: 10.1016/j.ymgme.2012.08.010. Epub 2012 Aug 18. Mol Genet Metab. 2012. PMID: 22944366

9

Molecular Dynamics Study on the Inhibition Mechanisms of Drugs CQ1-3 for Alzheimer Amyloid-β40 Aggregation Induced by Cu(2.).

Dong M, Li H, Hu D, Zhao W, Zhu X, Ai H. Dong M, et al. ACS Chem Neurosci. 2016 May 18;7(5):599-614. doi: 10.1021/acschemneuro.5b00343. Epub 2016 Feb 24. ACS Chem Neurosci. 2016. PMID: 26871000

10

N-Terminus Binding Preference for Either Tanshinone or Analogue in Both Inhibition of Amyloid Aggregation and Disaggregation of Preformed Amyloid Fibrils-Toward Introducing a Kind of Novel Anti-Alzheimer Compounds.

Dong M, Zhao W, Hu D, Ai H, Kang B. Dong M, et al. ACS Chem Neurosci. 2017 Jul 19;8(7):1577-1588. doi: 10.1021/acschemneuro.7b00080. Epub 2017 Apr 28. ACS Chem Neurosci. 2017. PMID: 28406293

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