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31542863,31889239,25150284,28621624,31215469,26091668,32861131,29547090,33866029,31623667,34148105,32385699,31125770,35695190,35844028,30496526,35815721,34087795,30187121,24511544,23289977,32027343,31804140,28765916,34952640,31639630,33486679,31623593,34074252,31468161,31545245,29721688,28401334,29031038,28339723,33059718,32440969,32554237,26194445,29016839,30333046,32034446,32647886,34067658,30877769,33142244,36915208,27401154,30326163,27522495,32291242,29198322,28507382,27764705,35648306,30831643,34142341,33317554,26493382,31349875,27593971,29912767,28223536,25701198,26757882,35708480,30756272,32620753,29663171,29941484,31324999,36248907,28956184,26934681,30298540,26068765,34461927,35175545,30572911,30710203,31346613,33235995,25434382,32762688,32078014,33215342,33801093,30011045,27626492,33509914,23184331,35212929,28889246,25931051,28392842,30222900,27526690,15936158,25727226,36418240,29676695,29687258,27571882,28884377,34797526,33492602,33972663,28887717,33992170,34088969,34794192,19805672,25429835,31134296,34138894,28574310,23438035,37043844,33868245,34131647,35763095,34929638,34651653,24997139,31921684,34060283,32761533,36841906,35779193,32222932,35661403,33134923,26945349,34377594,27849434,34078827,33982756,34756799,31632497,36529434,32534425,33157564,33216326,31177992,34193272,33887544,36988764,29632085,35505351,31751860,31923345,35660939,31034050,33239433,30259105,34301201,34625582,20129251,23988086,35291535,35762826,34875075,35911637,29990498,30848102,35849035,35641844,33516867,34997451,31938968,34307160,36105052,35362874,22291905,36091049,34667950,34284982,28339964,30926639,30113792,31845844,35050747,36579028,31608326,20197289,33615225,34647022,33959491,32310827,35699848,32080088,35345371,29794775,26354773,33045388,34732244,34257410,31661039,31666247,33130898,32355162,30854062,29509313,24330732,32929611,35562131,35118384,32918998,32546647,23762372,24986561,27926792,22492960,32498488,32918970,36609243,31969485,19915670,23225805,35474131,32885540,20446891,24292886,33578746,33130858,33807423,33692940,34222249,33887763,29664032,33685995,25201236,25103728,34123575,32915403,36035640,33172155,32870144,36609238,35951724,31480372,24056404,33325513,35756624,32762134,31829033,32564972,20824044,35682709,31907277,34152549,32565936,33675391,35419733,35327982,35192890,33067480,31801254,30154718,31628288,34335936,33881725,36183188,33543653,35716311,31667475,34055603,36239836,36122307,24005813,33556173,27399113,35378641,36898299,31400201,30859746,33937133,24421847,23819258,34982879,31423255,34643775,24896337,30873456,24990827,33889755,23236348,35406793,34236262,35875139,36575552,34715662,36294373,32830856,33987411,22747609,32606935,33297360,35017570,32197147,32488994,36400876,34191225,33237934,28975017,36996926,33161654,35171829,33761391,36841881,33603461,27888226,35667845,35667844,34044551,31443071,34332627,34764443,35911333,25136839,32024367,29666969,31143523,35912242,32791525,23432647,32745649,32082376,33765226,36451503,30713788,35817573,34873478,37128507,32349217,31963499,35788291,33975256,37060448,33065606,35698739,33742279,32875565,34305772,35022089,35185770,24893890,37001387,34878541,36980184,34830766,35079543,36093544,31357584,23917401,31788085,35817574,31327527,35974956,33074125,36566697,25092745,33756171,24557936,31908666,35767937,27800031,35913110,33142709,33995529,36380219,35381788,36612169,35259554,35499760,33274363,32153627,21383741,34393714,36382106,33552257,37132598,30267146,33304303,25024889,26136784,34926307,34514585,33537891,36707424,36368458,32642673,36225424,24349039,34956900,32642725,31713017,35715666,37046694,31511900,28969132,32796143,35486306,32190845,34572759,29599982,35212838,35059640,33922652,32478280,30987226,33552990,34355171,35096403,31555453,35953681,31592000,29675108,29721393,34286278,31308765,36831791,35890294,33392505,28168132,27051584,30123089,32649821,30920523,28658749,36367033,31726354,32626586,36497413,31950162,34094991,35785151,35876685,36547116,31628474,36445104,35122081,29312129,31218286,30997093,32891454,36285199,32642665[uid]

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Negative prognostic impact of epidermal growth factor receptor copy number gain in young adults with isocitrate dehydrogenase wild-type glioblastoma.

Hoffman DI, Abdullah KG, McCoskey M, Binder ZA, O'Rourke DM, Desai AS, Nasrallah MP, Bigdeli A, Morrissette JJD, Brem S, Bagley SJ. Hoffman DI, et al. J Neurooncol. 2019 Nov;145(2):321-328. doi: 10.1007/s11060-019-03298-6. Epub 2019 Sep 21. J Neurooncol. 2019. PMID: 31542863

EGFR amplification is a real independent prognostic impact factor between young adults and adults over 45yo with wild-type glioblastoma?

Armocida D, Pesce A, Frati A, Santoro A, Salvati M. Armocida D, et al. J Neurooncol. 2020 Jan;146(2):275-284. doi: 10.1007/s11060-019-03364-z. Epub 2019 Dec 30. J Neurooncol. 2020. PMID: 31889239

Combined analysis of TERT, EGFR, and IDH status defines distinct prognostic glioblastoma classes.

Labussière M, Boisselier B, Mokhtari K, Di Stefano AL, Rahimian A, Rossetto M, Ciccarino P, Saulnier O, Paterra R, Marie Y, Finocchiaro G, Sanson M. Labussière M, et al. Neurology. 2014 Sep 23;83(13):1200-6. doi: 10.1212/WNL.0000000000000814. Epub 2014 Aug 22. Neurology. 2014. PMID: 25150284

Use of telomerase promoter mutations to mark specific molecular subsets with reciprocal clinical behavior in IDH mutant and IDH wild-type diffuse gliomas.

Akyerli CB, Yüksel Ş, Can Ö, Erson-Omay EZ, Oktay Y, Coşgun E, Ülgen E, Erdemgil Y, Sav A, von Deimling A, Günel M, Yakıcıer MC, Pamir MN, Özduman K. Akyerli CB, et al. J Neurosurg. 2018 Apr;128(4):1102-1114. doi: 10.3171/2016.11.JNS16973. Epub 2017 Jun 16. J Neurosurg. 2018. PMID: 28621624

Distribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohorts.

Umehara T, Arita H, Yoshioka E, Shofuda T, Kanematsu D, Kinoshita M, Kodama Y, Mano M, Kagawa N, Fujimoto Y, Okita Y, Nonaka M, Nakajo K, Uda T, Tsuyuguchi N, Fukai J, Fujita K, Sakamoto D, Mori K, Kishima H, Kanemura Y. Umehara T, et al. Acta Neuropathol Commun. 2019 Jun 18;7(1):99. doi: 10.1186/s40478-019-0749-8. Acta Neuropathol Commun. 2019. PMID: 31215469 Free PMC article.

DNA copy number analysis of Grade II-III and Grade IV gliomas reveals differences in molecular ontogeny including chromothripsis associated with IDH mutation status.

Cohen A, Sato M, Aldape K, Mason CC, Alfaro-Munoz K, Heathcock L, South ST, Abegglen LM, Schiffman JD, Colman H. Cohen A, et al. Acta Neuropathol Commun. 2015 Jun 20;3:34. doi: 10.1186/s40478-015-0213-3. Acta Neuropathol Commun. 2015. PMID: 26091668 Free PMC article.

Is Ki-67 index overexpression in IDH wild type glioblastoma a predictor of shorter Progression Free survival? A clinical and Molecular analytic investigation.

Armocida D, Frati A, Salvati M, Santoro A, Pesce A. Armocida D, et al. Clin Neurol Neurosurg. 2020 Nov;198:106126. doi: 10.1016/j.clineuro.2020.106126. Epub 2020 Aug 3. Clin Neurol Neurosurg. 2020. PMID: 32861131

Prognostic role of mitochondrial pyruvate carrier in isocitrate dehydrogenase-mutant glioma.

Karsy M, Guan J, Huang LE. Karsy M, et al. J Neurosurg. 2018 Mar 16;130(1):56-66. doi: 10.3171/2017.9.JNS172036. J Neurosurg. 2018. PMID: 29547090

Genomic Prognosticators and Extent of Resection in Molecularly Subtyped World Health Organization Grade II and III Gliomas-A Single-Institution, Nine-Year Data.

Lasica AB, Jaunmuktane Z, Fersht N, Kirkman MA, Dixon L, Hoskote C, Brandner S, Samandouras G. Lasica AB, et al. World Neurosurg. 2021 Jul;151:e217-e233. doi: 10.1016/j.wneu.2021.04.026. Epub 2021 Apr 15. World Neurosurg. 2021. PMID: 33866029

The prognostic role of IDH mutations in homogeneously treated patients with anaplastic astrocytomas and glioblastomas.

Christians A, Adel-Horowski A, Banan R, Lehmann U, Bartels S, Behling F, Barrantes-Freer A, Stadelmann C, Rohde V, Stockhammer F, Hartmann C. Christians A, et al. Acta Neuropathol Commun. 2019 Oct 17;7(1):156. doi: 10.1186/s40478-019-0817-0. Acta Neuropathol Commun. 2019. PMID: 31623667 Free PMC article.

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