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Mammalian ECD Protein Is a Novel Negative Regulator of the PERK Arm of the Unfolded Protein Response.

Olou AA, Sarkar A, Bele A, Gurumurthy CB, Mir RA, Ammons SA, Mirza S, Saleem I, Urano F, Band H, Band V. Olou AA, et al. Mol Cell Biol. 2017 Aug 28;37(18):e00030-17. doi: 10.1128/MCB.00030-17. Print 2017 Sep 15. Mol Cell Biol. 2017. PMID: 28652267 Free PMC article.

The Human Cytomegalovirus Endoplasmic Reticulum-Resident Glycoprotein UL148 Activates the Unfolded Protein Response.

Siddiquey MNA, Zhang H, Nguyen CC, Domma AJ, Kamil JP. Siddiquey MNA, et al. J Virol. 2018 Sep 26;92(20):e00896-18. doi: 10.1128/JVI.00896-18. Print 2018 Oct 15. J Virol. 2018. PMID: 30045994 Free PMC article.

Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.

Hulmi JJ, Hentilä J, DeRuisseau KC, Oliveira BM, Papaioannou KG, Autio R, Kujala UM, Ritvos O, Kainulainen H, Korkmaz A, Atalay M. Hulmi JJ, et al. Free Radic Biol Med. 2016 Oct;99:308-322. doi: 10.1016/j.freeradbiomed.2016.08.017. Epub 2016 Aug 20. Free Radic Biol Med. 2016. PMID: 27554968

TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.

Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A. Tsukumo Y, et al. PLoS One. 2014 Nov 13;9(11):e112761. doi: 10.1371/journal.pone.0112761. eCollection 2014. PLoS One. 2014. PMID: 25393282 Free PMC article.

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

Teske BF, Wek SA, Bunpo P, Cundiff JK, McClintick JN, Anthony TG, Wek RC. Teske BF, et al. Mol Biol Cell. 2011 Nov;22(22):4390-405. doi: 10.1091/mbc.E11-06-0510. Epub 2011 Sep 14. Mol Biol Cell. 2011. PMID: 21917591 Free PMC article.

The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout.

Ogborn DI, McKay BR, Crane JD, Parise G, Tarnopolsky MA. Ogborn DI, et al. Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15;307(6):R664-9. doi: 10.1152/ajpregu.00511.2013. Epub 2014 Jul 9. Am J Physiol Regul Integr Comp Physiol. 2014. PMID: 25009220 Free article. Clinical Trial.

The PERK Arm of the Unfolded Protein Response Negatively Regulates Transmissible Gastroenteritis Virus Replication by Suppressing Protein Translation and Promoting Type I Interferon Production.

Xue M, Fu F, Ma Y, Zhang X, Li L, Feng L, Liu P. Xue M, et al. J Virol. 2018 Jul 17;92(15):e00431-18. doi: 10.1128/JVI.00431-18. Print 2018 Aug 1. J Virol. 2018. PMID: 29769338 Free PMC article.

Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.

Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, Cavener DR, Imaizumi K. Saito A, et al. J Biol Chem. 2011 Feb 11;286(6):4809-18. doi: 10.1074/jbc.M110.152900. Epub 2010 Dec 6. J Biol Chem. 2011. PMID: 21135100 Free PMC article.

The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response.

Merlot AM, Porter GM, Sahni S, Lim EG, Peres P, Richardson DR. Merlot AM, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2094-2110. doi: 10.1016/j.bbadis.2019.04.007. Epub 2019 Apr 11. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30981813 Free article.

Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα.

Baird TD, Palam LR, Fusakio ME, Willy JA, Davis CM, McClintick JN, Anthony TG, Wek RC. Baird TD, et al. Mol Biol Cell. 2014 May;25(10):1686-97. doi: 10.1091/mbc.E14-02-0704. Epub 2014 Mar 19. Mol Biol Cell. 2014. PMID: 24648495 Free PMC article.

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