Similar articles for PMID: 28623128

Year	Number of Results
1977	1
1989	1
2002	1
2003	1
2005	2
2007	1
2008	1
2009	5
2010	6
2011	12
2012	16
2013	27
2014	22
2015	31
2016	29
2017	46
2018	55
2019	48
2020	51
2021	28
2022	34
2023	8
2024	0

1

Targeting PI3K-AKT-mTOR by LY3023414 inhibits human skin squamous cell carcinoma cell growth in vitro and in vivo.

Zou Y, Ge M, Wang X. Zou Y, et al. Biochem Biophys Res Commun. 2017 Aug 19;490(2):385-392. doi: 10.1016/j.bbrc.2017.06.052. Epub 2017 Jun 13. Biochem Biophys Res Commun. 2017. PMID: 28623128

2

Targeting sphingosine kinase 2 by ABC294640 inhibits human skin squamous cell carcinoma cell growth.

Zhou J, Chen J, Yu H. Zhou J, et al. Biochem Biophys Res Commun. 2018 Mar 4;497(2):535-542. doi: 10.1016/j.bbrc.2018.02.075. Epub 2018 Feb 8. Biochem Biophys Res Commun. 2018. PMID: 29428730

3

Characterization of LY3023414, a Novel PI3K/mTOR Dual Inhibitor Eliciting Transient Target Modulation to Impede Tumor Growth.

Smith MC, Mader MM, Cook JA, Iversen P, Ajamie R, Perkins E, Bloem L, Yip YY, Barda DA, Waid PP, Zeckner DJ, Young DA, Sanchez-Felix M, Donoho GP, Wacheck V. Smith MC, et al. Mol Cancer Ther. 2016 Oct;15(10):2344-2356. doi: 10.1158/1535-7163.MCT-15-0996. Epub 2016 Jul 20. Mol Cancer Ther. 2016. PMID: 27439478

4

GDC-0084 inhibits cutaneous squamous cell carcinoma cell growth.

Ding LT, Zhao P, Yang ML, Lv GZ, Zhao TL. Ding LT, et al. Biochem Biophys Res Commun. 2018 Sep 10;503(3):1941-1948. doi: 10.1016/j.bbrc.2018.07.139. Epub 2018 Jul 30. Biochem Biophys Res Commun. 2018. PMID: 30072096

5

PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer.

Herzog A, Bian Y, Vander Broek R, Hall B, Coupar J, Cheng H, Sowers AL, Cook JD, Mitchell JB, Chen Z, Kulkarni AB, Van Waes C. Herzog A, et al. Clin Cancer Res. 2013 Jul 15;19(14):3808-19. doi: 10.1158/1078-0432.CCR-12-2716. Epub 2013 May 2. Clin Cancer Res. 2013. PMID: 23640975 Free PMC article.

6

Targeting the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway: an emerging treatment strategy for squamous cell lung carcinoma.

Beck JT, Ismail A, Tolomeo C. Beck JT, et al. Cancer Treat Rev. 2014 Sep;40(8):980-9. doi: 10.1016/j.ctrv.2014.06.006. Epub 2014 Jul 3. Cancer Treat Rev. 2014. PMID: 25037117 Review.

7

Autophagy inhibition sensitizes LY3023414-induced anti-glioma cell activity in vitro and in vivo.

Zheng L, Li H, Mo Y, Qi G, Liu B, Zhao J. Zheng L, et al. Oncotarget. 2017 Oct 27;8(58):98964-98973. doi: 10.18632/oncotarget.22147. eCollection 2017 Nov 17. Oncotarget. 2017. PMID: 29228741 Free PMC article.

8

α-Mangostin inhibits DMBA/TPA-induced skin cancer through inhibiting inflammation and promoting autophagy and apoptosis by regulating PI3K/Akt/mTOR signaling pathway in mice.

Wang F, Ma H, Liu Z, Huang W, Xu X, Zhang X. Wang F, et al. Biomed Pharmacother. 2017 Aug;92:672-680. doi: 10.1016/j.biopha.2017.05.129. Epub 2017 Jun 3. Biomed Pharmacother. 2017. PMID: 28582759

9

Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice.

Chamcheu JC, Adhami VM, Esnault S, Sechi M, Siddiqui IA, Satyshur KA, Syed DN, Dodwad SM, Chaves-Rodriquez MI, Longley BJ, Wood GS, Mukhtar H. Chamcheu JC, et al. Antioxid Redox Signal. 2017 Jan 10;26(2):49-69. doi: 10.1089/ars.2016.6769. Epub 2016 Oct 4. Antioxid Redox Signal. 2017. PMID: 27393705 Free PMC article.

10

A First-in-Human Phase 1 Study of LY3023414, an Oral PI3K/mTOR Dual Inhibitor, in Patients with Advanced Cancer.

Bendell JC, Varghese AM, Hyman DM, Bauer TM, Pant S, Callies S, Lin J, Martinez R, Wickremsinhe E, Fink A, Wacheck V, Moore KN. Bendell JC, et al. Clin Cancer Res. 2018 Jul 15;24(14):3253-3262. doi: 10.1158/1078-0432.CCR-17-3421. Epub 2018 Apr 10. Clin Cancer Res. 2018. PMID: 29636360 Clinical Trial.

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