gda guanine deaminase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gdaprovided by ZNC
Official Full Name: guanine deaminaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-434
See related: Ensembl:ENSDARG00000002986 AllianceGenome:ZFIN:ZDB-GENE-050522-434
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:112282
Summary: Predicted to enable guanine deaminase activity and zinc ion binding activity. Predicted to be involved in guanine metabolic process. Predicted to be active in cytosol. Orthologous to human GDA (guanine deaminase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (25708369..25723059, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (25108216..25122906, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables guanine deaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables guanine deaminase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within guanine catabolic process	IEA Inferred from Electronic Annotation more info
involved_in guanine catabolic process	IEA Inferred from Electronic Annotation more info
involved_in guanine metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: guanine deaminase

NP_001018510.1

EC 3.5.4.3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020674.1 → NP_001018510.1 guanine deaminase

See identical proteins and their annotated locations for NP_001018510.1

Status: PROVISIONAL

Source sequence(s)

BC095728

UniProtKB/TrEMBL

Q502E8

Related

ENSDARP00000010155.7, ENSDART00000014013.9

Conserved Domains (1) summary

cl00281
Location:14 → 441

metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...