SLC2A9 solute carrier family 2 member 9 [Homo sapiens (human)] - Gene

Summary

Official Symbol: SLC2A9provided by HGNC
Official Full Name: solute carrier family 2 member 9provided by HGNC
Primary source: HGNC:HGNC:13446
See related: Ensembl:ENSG00000109667 MIM:606142; AllianceGenome:HGNC:13446
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: GLUT9; GLUTX; UAQTL2; URATv1
Summary: This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Expression: Broad expression in kidney (RPKM 4.4), liver (RPKM 1.6) and 18 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 4p16.1

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	4	NC_000004.12 (9771025..10040270, complement)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	4	NC_060928.1 (9770809..10039839, complement)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	4	NC_000004.11 (9827848..10041894, complement)

Chromosome 4 - NC_000004.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Raised CK and acute kidney injury following intense exercise in three patients with a history of exercise intolerance due to homozygous mutations in SLC2A9.
Title: Raised CK and acute kidney injury following intense exercise in three patients with a history of exercise intolerance due to homozygous mutations in SLC2A9.
GLUT9 as a potential drug target for chronic kidney disease: Drug target validation by a Mendelian randomization study.
Title: GLUT9 as a potential drug target for chronic kidney disease: Drug target validation by a Mendelian randomization study.
Pathogenic Variants of SLC22A12 (URAT1) and SLC2A9 (GLUT9) in Spanish Patients with Renal Hypouricemia: Founder Effect of SLC2A9 Variant c.374C>T; p.(T125M).
Title: Pathogenic Variants of SLC22A12 (URAT1) and SLC2A9 (GLUT9) in Spanish Patients with Renal Hypouricemia: Founder Effect of SLC2A9 Variant c.374C>T; p.(T125M).
The in-silico evaluation of important GLUT9 residue for uric acid transport based on renal hypouricemia type 2.
Title: The in-silico evaluation of important GLUT9 residue for uric acid transport based on renal hypouricemia type 2.
The regulation effect of GLUT9/SLC2A9 on intrahepatic uric acid level and metabolic associated fatty liver disease.
Title: The regulation effect of GLUT9/SLC2A9 on intrahepatic uric acid level and metabolic associated fatty liver disease.
Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System.
Title: Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System.
The effects of hyperuricemia on endothelial cells are mediated via GLUT9 and the JAK2/STAT3 pathway.
Title: The effects of hyperuricemia on endothelial cells are mediated via GLUT9 and the JAK2/STAT3 pathway.
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus.
Title: Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus.
The haplotype of SLC2A9_rs3733591, PKD2_rs2725220 and ABCG2_rs2231142 increases the hyperuricaemia risk and alcohol, chicken and processed meat intakes and smoking interact with its risk.
Title: The haplotype of SLC2A9_rs3733591, PKD2_rs2725220 and ABCG2_rs2231142 increases the hyperuricaemia risk and alcohol, chicken and processed meat intakes and smoking interact with its risk.
Renal Reabsorptive Transport of Uric Acid Precursor Xanthine by URAT1 and GLUT9.
Title: Renal Reabsorptive Transport of Uric Acid Precursor Xanthine by URAT1 and GLUT9.

Submit: New GeneRIF Correction See all GeneRIFs (145)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description	Tests
Hypouricemia, renal, 2 MedGen: C2677549 OMIM: 612076 GeneReviews: Not available	Compare labs

EBI GWAS Catalog

Description
A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls. EBI GWAS Catalog EBI GWAS CatalogPubMed
A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population. EBI GWAS Catalog EBI GWAS CatalogPubMed
A genome-wide association study of serum uric acid in African Americans. EBI GWAS Catalog EBI GWAS CatalogPubMed
An atlas of genetic influences on human blood metabolites. EBI GWAS Catalog EBI GWAS CatalogPubMed
Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish. EBI GWAS Catalog EBI GWAS CatalogPubMed
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. EBI GWAS Catalog EBI GWAS CatalogPubMed
Evidence of gene-environment interaction for two genes on chromosome 4 and environmental tobacco smoke in controlling the risk of nonsyndromic cleft palate. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association of serum uric acid concentration: replication of sequence variants in an island population of the Adriatic coast of Croatia. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association study of Alzheimer's disease with psychotic symptoms. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association study of biochemical traits in Korcula Island, Croatia. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association study of hematological and biochemical traits in a Japanese population. EBI GWAS Catalog EBI GWAS CatalogPubMed
Human metabolic individuality in biomedical and pharmaceutical research. EBI GWAS Catalog EBI GWAS CatalogPubMed
Identification of low-frequency variants associated with gout and serum uric acid levels. EBI GWAS Catalog EBI GWAS CatalogPubMed
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. EBI GWAS Catalog EBI GWAS CatalogPubMed
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. EBI GWAS Catalog EBI GWAS CatalogPubMed
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. EBI GWAS Catalog EBI GWAS CatalogPubMed
SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. EBI GWAS Catalog EBI GWAS CatalogPubMed
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. EBI GWAS Catalog EBI GWAS CatalogPubMed
The genetic architecture of economic and political preferences. EBI GWAS Catalog EBI GWAS CatalogPubMed
The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D4S615 (e-PCR)
- UniSTS:36099

L18084 (e-PCR)
- UniSTS:46086

G65185 (e-PCR)
- UniSTS:230671

G65186 (e-PCR)
- UniSTS:230672

G65187 (e-PCR)
- UniSTS:230673

G65145 (e-PCR)
- UniSTS:230695

SHGC-50921 (e-PCR)
- UniSTS:18472

SHGC-25155 (e-PCR)
- UniSTS:36143

SHGC-154066 (e-PCR)
- UniSTS:183870

D4S1251 (e-PCR)
- UniSTS:9049

G65164 (e-PCR)
- UniSTS:230763

RH36271 (e-PCR)
- UniSTS:44913

D4S1268 (e-PCR)
- UniSTS:2434

D4S634 (e-PCR)
- UniSTS:52354

D4S317 (e-PCR)
- UniSTS:14487

SHGC-51391 (e-PCR)
- UniSTS:9398

D4S1365 (e-PCR)
- UniSTS:65209

SHGC-51591 (e-PCR)
- UniSTS:25553

G41975 (e-PCR)
- UniSTS:77779

SHGC-148773 (e-PCR)
- UniSTS:176600

SHGC-148774 (e-PCR)
- UniSTS:176601

SHGC-59716 (e-PCR)
- UniSTS:45281

G33346 (e-PCR)
- UniSTS:81640

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables carbohydrate:proton symporter activity	NAS Non-traceable Author Statement more info	PubMed
enables fructose transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables glucose transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables hexose transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables transmembrane transporter activity	TAS Traceable Author Statement more info
enables urate transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in fructose transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
involved_in glucose transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
involved_in glucose transmembrane transport	NAS Non-traceable Author Statement more info	PubMed
involved_in hexose transmembrane transport	TAS Traceable Author Statement more info
involved_in monosaccharide transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in urate metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in urate transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info
located_in basolateral plasma membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	TAS Traceable Author Statement more info

General protein information

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Preferred Names: solute carrier family 2, facilitated glucose transporter member 9

Names: GLUT-9; glucose transporter type 9; human glucose transporter-like protein-9; solute carrier family 2 (facilitated glucose transporter), member 9; urate transporter; urate voltage-driven efflux transporter 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_011540.2 RefSeqGene

Range

23773..219046

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001001290.2 → NP_001001290.1 solute carrier family 2, facilitated glucose transporter member 9 isoform 2

Status: REVIEWED

Description

Transcript Variant: This variant (2), also known as GLUT9deltaN, contains alternate in-frame segments in the 5' UTR and coding region and uses a different start codon, compared to variant 1. Isoform 2 has a shorter N-terminus, compared to isoform 1.

Source sequence(s)

AC005674, AL572022, BC018897, CD629822

Consensus CDS

CCDS3406.1

Related

ENSP00000311383.3, ENST00000309065.7

Conserved Domains (2) summary

cd06174
Location:32 → 469

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

pfam00083
Location:28 → 485

Sugar_tr; Sugar (and other) transporter
NM_020041.3 → NP_064425.2 solute carrier family 2, facilitated glucose transporter member 9 isoform 1

See identical proteins and their annotated locations for NP_064425.2

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the shorter transcript, and encodes the longer isoform (1).

Source sequence(s)

AC005674, AL572022, BC018897, BI821650, CD629819, CD629822

Consensus CDS

CCDS3407.1

UniProtKB/Swiss-Prot

Q0VGC4, Q4W5D1, Q8WV30, Q96P00, Q9NRM0

Related

ENSP00000264784.3, ENST00000264784.8

Conserved Domains (1) summary

cd17432
Location:59 → 510

MFS_GLUT_Class2; Class 2 Glucose transporters (GLUTs) of the Major Facilitator Superfamily

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000004.12 Reference GRCh38.p14 Primary Assembly

Range

9771025..10040270 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_011513867.4 → XP_011512169.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X21

Conserved Domains (1) summary

cd06174
Location:1 → 280

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
XM_011513858.2 → XP_011512160.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X3

See identical proteins and their annotated locations for XP_011512160.1

Conserved Domains (2) summary

cd06174
Location:32 → 437

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

TIGR00895
Location:26 → 433

2A0115; benzoate transport
XM_047415973.1 → XP_047271929.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X4
XM_011513856.4 → XP_011512158.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X1

Conserved Domains (2) summary

cd06174
Location:61 → 466

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

TIGR00895
Location:48 → 462

2A0115; benzoate transport
XM_017008457.3 → XP_016863946.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X2
XM_047415976.1 → XP_047271932.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X13
XM_024454151.2 → XP_024309919.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X12

Conserved Domains (1) summary

cl26863
Location:1 → 337

Sugar_tr; Sugar (and other) transporter
XM_017008459.2 → XP_016863948.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X16

Conserved Domains (1) summary

cl28910
Location:1 → 312

MFS; Major Facilitator Superfamily
XM_011513864.3 → XP_011512166.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X14

Conserved Domains (1) summary

cd06174
Location:10 → 330

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
XM_047415974.1 → XP_047271930.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X6
XM_006713968.5 → XP_006714031.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X5

Conserved Domains (2) summary

cd06174
Location:61 → 498

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

pfam00083
Location:57 → 514

Sugar_tr; Sugar (and other) transporter
XM_047415977.1 → XP_047271933.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X20
XM_011513861.4 → XP_011512163.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X11

Conserved Domains (2) summary

cd06174
Location:61 → 472

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

TIGR00895
Location:48 → 462

2A0115; benzoate transport
XM_017008458.3 → XP_016863947.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X10
XM_011513860.4 → XP_011512162.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X8

Conserved Domains (2) summary

cd06174
Location:61 → 498

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

pfam00083
Location:57 → 514

Sugar_tr; Sugar (and other) transporter
XM_011513859.4 → XP_011512161.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X7

Conserved Domains (2) summary

cd06174
Location:61 → 498

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

pfam00083
Location:57 → 514

Sugar_tr; Sugar (and other) transporter
XM_017008460.3 → XP_016863949.2 solute carrier family 2, facilitated glucose transporter member 9 isoform X22
XM_047415978.1 → XP_047271934.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X23
XM_047415975.1 → XP_047271931.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X9
XM_047415979.1 → XP_047271935.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X24
XM_011513865.3 → XP_011512167.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X17

Conserved Domains (2) summary

cd06174
Location:61 → 432

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

TIGR00895
Location:48 → 437

2A0115; benzoate transport
XM_011513866.3 → XP_011512168.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X18

Conserved Domains (1) summary

cd06174
Location:61 → 431

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
XM_047415980.1 → XP_047271936.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X25
XM_024454153.2 → XP_024309921.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X19

Conserved Domains (1) summary

cl26863
Location:57 → 432

Sugar_tr; Sugar (and other) transporter
XM_024454152.2 → XP_024309920.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X15

Conserved Domains (1) summary

cl26863
Location:57 → 433

Sugar_tr; Sugar (and other) transporter

Alternate T2T-CHM13v2.0

Genomic

NC_060928.1 Alternate T2T-CHM13v2.0

Range

9770809..10039839 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054350532.1 → XP_054206507.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X21
XM_054350514.1 → XP_054206489.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X3
XM_054350515.1 → XP_054206490.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X4
XM_054350512.1 → XP_054206487.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X1
XM_054350513.1 → XP_054206488.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X2
XM_054350524.1 → XP_054206499.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X13
XM_054350523.1 → XP_054206498.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X12
XM_054350527.1 → XP_054206502.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X16
XM_054350525.1 → XP_054206500.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X14
XM_054350517.1 → XP_054206492.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X6
XM_054350516.1 → XP_054206491.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X5
XM_054350531.1 → XP_054206506.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X20
XM_054350522.1 → XP_054206497.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X11
XM_054350521.1 → XP_054206496.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X10
XM_054350519.1 → XP_054206494.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X8
XM_054350518.1 → XP_054206493.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X7
XM_054350534.1 → XP_054206509.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X22
XM_054350535.1 → XP_054206510.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X23
XM_054350520.1 → XP_054206495.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X9
XM_054350536.1 → XP_054206511.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X24
XM_054350533.1 → XP_054206508.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X26
XM_054350528.1 → XP_054206503.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X17
XM_054350529.1 → XP_054206504.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X18
XM_054350537.1 → XP_054206512.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X25
XM_054350530.1 → XP_054206505.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X19
XM_054350526.1 → XP_054206501.1 solute carrier family 2, facilitated glucose transporter member 9 isoform X15