rps6kb1b ribosomal protein S6 kinase b, polypeptide 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rps6kb1bprovided by ZNC
Official Full Name: ribosomal protein S6 kinase b, polypeptide 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2038
See related: Ensembl:ENSDARG00000058230 AllianceGenome:ZFIN:ZDB-GENE-040426-2038
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: S6K1; fc51h01; rps6kb1; zgc:55713; wu:fc51h01
Summary: Predicted to enable ribosomal protein S6 kinase activity. Predicted to be involved in TOR signaling and peptidyl-serine phosphorylation. Predicted to act upstream of or within protein phosphorylation and signal transduction. Predicted to be located in ribosome. Predicted to be active in cytoplasm and nucleus. Orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (17407002..17424270)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (17470980..17488248)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Formimidoyltransferase cyclodeaminase prevents the starvation-induced liver hepatomegaly and dysfunction through downregulating mTORC1.
Title: Formimidoyltransferase cyclodeaminase prevents the starvation-induced liver hepatomegaly and dysfunction through downregulating mTORC1.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in peptidyl-serine phosphorylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ribosomal protein S6 kinase beta-1

Names: ribosomal protein S6 kinase 1; ribosomal protein S6 kinase b, polypeptide 1; ribosomal protein S6 kinase, polypeptide 1

NP_998241.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213076.1 → NP_998241.1 ribosomal protein S6 kinase beta-1

See identical proteins and their annotated locations for NP_998241.1

Status: PROVISIONAL

Source sequence(s)

BC046888

UniProtKB/TrEMBL

Q802Y7

Related

ENSDARP00000075502.4, ENSDART00000081059.5

Conserved Domains (2) summary

smart00220
Location:65 → 326

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd05584
Location:68 → 390

STKc_p70S6K; Catalytic domain of the Serine/Threonine Kinase, 70 kDa ribosomal protein S6 kinase