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    FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100345480, updated on 8-Mar-2024

    Summary

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    Gene symbol
    FDFT1
    Gene description
    farnesyl-diphosphate farnesyltransferase 1
    See related
    Ensembl:ENSOCUG00000005160
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 2 NC_067375.1 (38654813..38682579, complement)

    Chromosome 2 - NC_067375.1Genomic Context describing neighboring genes Neighboring gene defensin beta 136 Neighboring gene cathepsin B Neighboring gene nei like DNA glycosylase 2 Neighboring gene GATA binding protein 4 Neighboring gene pre-mRNA-splicing factor 38B-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067375.1 Chromosome 2 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables farnesyl-diphosphate farnesyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables squalene synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in farnesyl diphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    squalene synthase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067375.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      38654813..38682579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002709437.4 → XP_002709483.1  squalene synthase isoform X2

      UniProtKB/TrEMBL
      A0A5F9DGX2, G1SNB5
      Related
      ENSOCUP00000004469.2
      Conserved Domains (1) summary
      cl00210
      Location:38 → 370
      Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

    2. XM_008248858.3 → XP_008247080.1  squalene synthase isoform X1

      UniProtKB/TrEMBL
      A0A5F9CK73, U3KPG8
      Related
      ENSOCUP00000027128.2
      Conserved Domains (1) summary
      TIGR01559
      Location:93 → 425
      squal_synth; farnesyl-diphosphate farnesyltransferase
    Nucleotide Protein
    Heading Accession and Version

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