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    P2RX7 purinergic receptor P2X 7 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 452318, updated on 29-Mar-2024

    Summary

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    Official Symbol
    P2RX7provided by VGNC
    Official Full Name
    purinergic receptor P2X 7provided by VGNC
    Primary source
    VGNC:VGNC:8488
    Locus tag
    CK820_G0021646
    See related
    Ensembl:ENSPTRG00000005554
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (127966530..128020870)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (126579035..126633408)

    Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene small nucleolar RNA SNORA70 Neighboring gene purinergic receptor P2X 4 Neighboring gene calcium/calmodulin dependent protein kinase kinase 2 Neighboring gene anaphase promoting complex subunit 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables extracellularly ATP-gated monoatomic cation channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables purinergic nucleotide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to ATP IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    P2X purinoceptor 7
    Names
    purinergic receptor P2X, ligand-gated ion channel, 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      127966530..128020870
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_509436.8 → XP_509436.2  P2X purinoceptor 7 isoform X2

      UniProtKB/TrEMBL
      A0A2J8MDJ1, A0A6D2WD36, H2R737
      Related
      ENSPTRP00000049853.2
      Conserved Domains (1) summary
      pfam00864
      Location:11 → 397
      P2X_receptor; ATP P2X receptor

    2. XM_063785117.1 → XP_063641187.1  P2X purinoceptor 7 isoform X1

    Nucleotide Protein
    Heading Accession and Version

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