NBR1 NBR1 autophagy cargo receptor [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: NBR1
Gene description: NBR1 autophagy cargo receptor
Locus tag: CR201_G0051413
See related: Ensembl:ENSPPYG00000008362
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	19	NC_072004.2 (73447922..73488560)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	Unplaced Scaffold	NW_026537337.1 (13712974..13753426)

Chromosome 19 - NC_072004.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D17S1970 (e-PCR)
- UniSTS:81438

G01753 (e-PCR)
- UniSTS:19797

GDB:439146 (e-PCR)
- UniSTS:157289

RH47766 (e-PCR)
- UniSTS:3434

WI-21206 (e-PCR)
- UniSTS:47800

D17S1221 (e-PCR)
- UniSTS:60879

RH25285 (e-PCR)
- UniSTS:34260

D17S1461E (e-PCR)
- UniSTS:150502

STS-U25764 (e-PCR)
- UniSTS:70137

RH70398 (e-PCR)
- UniSTS:82425

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ubiquitin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in macroautophagy	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in phagophore assembly site	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: next to BRCA1 gene 1 protein

Names: neighbor of BRCA1 gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001133837.1 → NP_001127309.1 next to BRCA1 gene 1 protein

See identical proteins and their annotated locations for NP_001127309.1

Status: PROVISIONAL

Source sequence(s)

CR858386

UniProtKB/Swiss-Prot

Q5RC94

UniProtKB/TrEMBL

A0A8I5TSH9

Related

ENSPPYP00000043413.1, ENSPPYT00000057934.1

Conserved Domains (4) summary

cd06396
Location:5 → 85

PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...

cd02340
Location:215 → 259

ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...

cd14319
Location:844 → 882

UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins

cd14947
Location:299 → 409

NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins