U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    RBPJ recombination signal binding protein for immunoglobulin kappa J region [ Equus caballus (horse) ]

    Gene ID: 100055547, updated on 8-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RBPJprovided by VGNC
    Official Full Name
    recombination signal binding protein for immunoglobulin kappa J regionprovided by VGNC
    Primary source
    VGNC:VGNC:51302
    See related
    Ensembl:ENSECAG00000019257
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 3 NC_009146.3 (100479400..100594559, complement)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 3 NC_009146.2 (98664598..98730610, complement)

    Chromosome 3 - NC_009146.3Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 19 Neighboring gene cholecystokinin A receptor Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L23a Neighboring gene uncharacterized LOC111772935 Neighboring gene small integral membrane protein 20

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MAML1-RBP-Jkappa- ICN1 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    recombining binding protein suppressor of hairless
    Names
    recombining binding protein suppressor of hairless-like protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001301219.2 → NP_001288148.1  recombining binding protein suppressor of hairless

      See identical proteins and their annotated locations for NP_001288148.1

      Status: PROVISIONAL

      Source sequence(s)
      PJAA01000004
      UniProtKB/TrEMBL
      A0A3Q2I598
      Related
      ENSECAP00000017015.2, ENSECAT00000020717.4
      Conserved Domains (3) summary
      cd01176
      Location:336 → 432
      IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
      pfam09270
      Location:192 → 314
      BTD; Beta-trefoil DNA-binding domain
      pfam09271
      Location:34 → 159
      LAG1-DNAbind; LAG1, DNA binding

    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009146.3 Reference EquCab3.0 Primary Assembly

      Range
      100479400..100594559 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023636866.1 → XP_023492634.1  recombining binding protein suppressor of hairless isoform X1

      UniProtKB/TrEMBL
      F7E3E6
      Related
      ENSECAP00000082400.1, ENSECAT00000122970.1
      Conserved Domains (3) summary
      cd01176
      Location:453 → 549
      IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
      pfam09270
      Location:282 → 431
      BTD; Beta-trefoil DNA-binding domain
      pfam09271
      Location:151 → 280
      LAG1-DNAbind; LAG1, DNA binding
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous